Rosario Fernández-Plata , Laura Gochicoa-Rangel , Rogelio Pérez-Padilla , Anjarath Higuera-Iglesias , Christian Rodríguez-Hernández , Dalia Cano-Jimenez , Midori Pérez-Kawabe , Manuel Castillejos-López , David Martínez-Briseño
{"title":"Evaluation of the Adjustment of Reference Equations for Impulse Oscillometry in Subjects With Down Syndrome Living in Mexico City","authors":"Rosario Fernández-Plata , Laura Gochicoa-Rangel , Rogelio Pérez-Padilla , Anjarath Higuera-Iglesias , Christian Rodríguez-Hernández , Dalia Cano-Jimenez , Midori Pérez-Kawabe , Manuel Castillejos-López , David Martínez-Briseño","doi":"10.1016/j.arbres.2024.12.018","DOIUrl":"10.1016/j.arbres.2024.12.018","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 5","pages":"Pages 305-307"},"PeriodicalIF":8.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Denise Rossato Silva , Emanuele Pontali , Yousra Kherabi , Lia D’Ambrosio , Rosella Centis , Giovanni Battista Migliori
{"title":"Post-TB Lung Disease: Where are we to Respond to This Priority?","authors":"Denise Rossato Silva , Emanuele Pontali , Yousra Kherabi , Lia D’Ambrosio , Rosella Centis , Giovanni Battista Migliori","doi":"10.1016/j.arbres.2025.03.001","DOIUrl":"10.1016/j.arbres.2025.03.001","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 5","pages":"Pages 262-263"},"PeriodicalIF":8.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuel Casal-Guisande , Cristina Represas-Represas , Rafael Golpe , Alberto Fernández-García , Almudena González-Montaos , Alberto Comesaña-Campos , Alberto Ruano-Raviña , Alberto Fernández-Villar
{"title":"Clinical and Social Characterization of Patients Hospitalized for COPD Exacerbation Using Machine Learning Tools","authors":"Manuel Casal-Guisande , Cristina Represas-Represas , Rafael Golpe , Alberto Fernández-García , Almudena González-Montaos , Alberto Comesaña-Campos , Alberto Ruano-Raviña , Alberto Fernández-Villar","doi":"10.1016/j.arbres.2024.10.010","DOIUrl":"10.1016/j.arbres.2024.10.010","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to employ machine learning (ML) tools to cluster patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease (COPD) based on their diverse social and clinical characteristics. This clustering is intended to facilitate the subsequent analysis of differences in clinical outcomes.</div></div><div><h3>Methods</h3><div>We analysed a cohort of patients with severe COPD from two Pulmonary Departments in north-western Spain using the k-prototypes algorithm, incorporating demographic, clinical, and social data. The resulting clusters were correlated with metrics such as readmissions, mortality, and place of death. Additionally, we developed an intelligent clinical decision support system (ICDSS) using a supervised ML model (Random Forest) to assign new patients to these clusters based on a reduced set of variables.</div></div><div><h3>Results</h3><div>The cohort consisted of 524 patients, with an average age of 70.30<!--> <!-->±<!--> <!-->9.35 years, 77.67% male, and an average FEV<sub>1</sub> of 44.43<!--> <!-->±<!--> <!-->15.4. Four distinct clusters (A–D) were identified with varying clinical–demographic and social profiles. Cluster D showed the highest levels of dependency, social isolation, and increased rates of readmissions and mortality. Cluster B was characterized by prevalent cardiovascular comorbidities. Cluster C included a younger demographic, with a higher proportion of women and significant psychosocial challenges. The ICDSS, using five key variables, achieved areas under the ROC curve of at least 0.91.</div></div><div><h3>Conclusions</h3><div>ML tools effectively facilitate the social and clinical clustering of patients with severe COPD, closely related to resource utilization and prognostic profiles. The ICDSS enhances the ability to characterize new patients in clinical settings.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 5","pages":"Pages 264-273"},"PeriodicalIF":8.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142685869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MeiLan K. Han , Michal Shteinberg , Deborah Assayag , Florence Schleich , Martino Pengo , Victoria M. Scicluna , Carolina Lombardi , Miriam Barrecheguren , Luis Jara-Palomares
{"title":"Respiratory Diseases in Women","authors":"MeiLan K. Han , Michal Shteinberg , Deborah Assayag , Florence Schleich , Martino Pengo , Victoria M. Scicluna , Carolina Lombardi , Miriam Barrecheguren , Luis Jara-Palomares","doi":"10.1016/j.arbres.2024.10.009","DOIUrl":"10.1016/j.arbres.2024.10.009","url":null,"abstract":"<div><div>Respiratory diseases exhibit diverse patterns in prevalence, clinical presentations, and outcomes between men and women. Historically, certain conditions were more prevalent in men, but trends have shifted, highlighting the need to understand sex disparities in respiratory health. Social, environmental, and healthcare changes have reshaped the landscape of respiratory diseases, complicating diagnosis and treatment. Moreover, the underrepresentation of women in clinical trials has limited our understanding of their specific needs. In this review, we explore the sex differences in the prevalence, clinical characteristics, and presentation of respiratory diseases, emphasizing the importance of tailored approaches to diagnosis and management. By recognizing and addressing these disparities, we can advance toward more equitable and effective respiratory healthcare for all individuals.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 5","pages":"Pages 290-298"},"PeriodicalIF":8.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142685870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marieke C. van der Molen , Rein Posthuma , Anouk W. Vaes , Martijn A. Spruit , Harry R. Gosker , Alain R. Viddeleer , Tineke P. Willems , Lowie E.G.W. Vanfleteren , Dirk-Jan Slebos , Jorine E. Hartman , on behalf of the SoLVE consortium group
{"title":"Metabolic Changes After Bronchoscopic Lung Volume Reduction With Endobronchial Valves in COPD Patients","authors":"Marieke C. van der Molen , Rein Posthuma , Anouk W. Vaes , Martijn A. Spruit , Harry R. Gosker , Alain R. Viddeleer , Tineke P. Willems , Lowie E.G.W. Vanfleteren , Dirk-Jan Slebos , Jorine E. Hartman , on behalf of the SoLVE consortium group","doi":"10.1016/j.arbres.2024.11.003","DOIUrl":"10.1016/j.arbres.2024.11.003","url":null,"abstract":"<div><h3>Objectives</h3><div>Little is known about the effect of bronchoscopic lung volume reduction using endobronchial valves (BLVR-EBV) on extrapulmonary manifestations like body composition, muscle function or metabolism. Pulmonary rehabilitation (PR) clearly addresses extrapulmonary manifestations of COPD, including physical inactivity and low muscle mass. However, the added impact of BLVR-EBV<!--> <!-->+<!--> <!-->PR remains unknown. Therefore, this study aimed to assess the effect of BLVR-EBV on body composition, muscle function and metabolic markers and whether PR has an additional impact on these outcomes.</div></div><div><h3>Methods</h3><div>Subjects with severe COPD eligible for both PR and BLVR-EBV were randomized into three groups: PR<!--> <!-->+<!--> <!-->BLVR-EBV, BLVR-EBV<!--> <!-->+<!--> <!-->PR, or only BLVR-EBV (<em>n</em> <!-->=<!--> <!-->97). Assessments included Dual Energy X-ray Absorptiometry, thigh muscle Computed Tomography, muscle strength measurements, accelerometry, and plasma (leptin, adiponectin, insulin, and triglycerides) at baseline and six months after the last intervention.</div></div><div><h3>Results</h3><div>A total of 74 participants completed the study. At follow-up, there were significant increases in the groups combined and both groups separated in total weight, lean mass, fat mass, muscle strength, daily physical activity, and triglyceride levels while leptin/fat mass ratio levels were significantly reduced. No differences were found between groups who underwent BLVR-EVR alone or BLVR-EBV with PR.</div></div><div><h3>Conclusions</h3><div>BLVR-EBV results in significant increases in body weight, lean and fat mass, muscle strength and daily physical activity level, and impacts on adipokine profile, irrespective of PR. This underscores the systemic benefits of addressing lung hyperinflation in patients with severe COPD.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 5","pages":"Pages 282-289"},"PeriodicalIF":8.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Gephine , Gaelle Terce , Gilles Brulois , Cécile Chenivesse , Olivier Le Rouzic , Jean-Marie Grosbois
{"title":"Home Versus Outpatient Pulmonary Rehabilitation in People With Chronic Obstructive Pulmonary Disease: An Unselected and Propensity-Matched Real-Life Study","authors":"Sarah Gephine , Gaelle Terce , Gilles Brulois , Cécile Chenivesse , Olivier Le Rouzic , Jean-Marie Grosbois","doi":"10.1016/j.arbres.2025.01.007","DOIUrl":"10.1016/j.arbres.2025.01.007","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 5","pages":"Pages 308-310"},"PeriodicalIF":8.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Organizing Pneumonia Caused by Letrozole Therapy for Breast Cancer: A Case Report","authors":"César Picado , Nestor Soler","doi":"10.1016/j.arbres.2025.01.016","DOIUrl":"10.1016/j.arbres.2025.01.016","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 5","pages":"Pages 319-320"},"PeriodicalIF":8.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucia Cayuela , Anna Michela Gaeta , Remedios Otero , Luis Jara-Palomares , Isabel Mendo Pedrajas , Aurelio Cayuela
{"title":"Regional Disparities and Trends in Venous Thromboembolism Mortality in Spain (1999–2022)","authors":"Lucia Cayuela , Anna Michela Gaeta , Remedios Otero , Luis Jara-Palomares , Isabel Mendo Pedrajas , Aurelio Cayuela","doi":"10.1016/j.arbres.2024.10.015","DOIUrl":"10.1016/j.arbres.2024.10.015","url":null,"abstract":"<div><h3>Aim</h3><div>This study aims to analyze trends in venous thromboembolism (VTE) mortality in the Spanish Autonomous Communities (ACs) from 1999 to 2022, with a focus on identifying regional disparities and informing targeted public health interventions.</div></div><div><h3>Methods</h3><div>Age-standardized mortality rates (ASMRs) were calculated using the European standard population as a reference. Joinpoint regression analysis was employed to identify significant changes in mortality trends, and geographical analysis was conducted using Bayesian inference to assess regional variations in mortality risk.</div></div><div><h3>Results</h3><div>From 1999 to 2022, Spain recorded 59,515 VTE-related deaths, with a higher proportion in women (59.4%) compared to men (40.6%). On a nationwide scale, VTE ASMRs showed a general decline for both men and women, with rates decreasing from 11.0 to 5.1 per 100,000 in men and from 9.2 to 4.4 per 100,000 in women. However, this decline was not uniform across all regions or demographic groups. Notably, mortality rates among younger individuals, particularly men, increased during the study period, highlighting the need for targeted interventions. Analysis revealed significant regional disparities, with higher mortality risks observed in Extremadura, Aragon, Navarre, and Andalusia, particularly for women.</div></div><div><h3>Conclusions</h3><div>This study provides valuable insights into the complex landscape of VTE mortality in Spain. While the overall decline in mortality is encouraging, persistent regional disparities and rising rates among younger individuals underscore the need for ongoing surveillance and targeted interventions.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 5","pages":"Pages 274-281"},"PeriodicalIF":8.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}