Archivos De Bronconeumologia最新文献

{"title":"The Worldwide Puzzle of Bronchiectasis Etiology in Adults","authors":"Miguel Angel Martinez-Garcia,&nbsp;Timothy Aksamit,&nbsp;Takanori Asakura,&nbsp;Lucy Burr,&nbsp;Chang Chia-Ling,&nbsp;Rosa Maria Giron,&nbsp;Wei-jie Guan,&nbsp;Deniz Kizilirmak,&nbsp;Yeon-Mok Oh,&nbsp;Miguel Penizzotto,&nbsp;Felix C. Ringshausen,&nbsp;Anthony de Soyza,&nbsp;Christina Thornton,&nbsp;Conroy Wong","doi":"10.1016/j.arbres.2025.11.012","DOIUrl":"10.1016/j.arbres.2025.11.012","url":null,"abstract":"<div><div>Bronchiectasis represents in frequency the third chronic inflammatory airway disease after chronic obstructive pulmonary disease (COPD) and asthma. It is produced by more than one hundred causes, both pulmonary and extrapulmonary. Despite advances in recent years in the understanding of this condition and the publication of several national and international guidelines on its management, in most cases the etiology remains unknown. Among the identified etiological forms, post-infectious and post-tuberculous are the most frequent. It is also striking how bronchiectasis associated with COPD and severe asthma has been progressively increasing over the years, probably due to greater awareness among healthcare professionals of the importance of such associations and the wider use of chest computed tomography (the diagnostic method of choice for bronchiectasis from a radiological perspective). However, it is remarkable, according to data obtained from national and international bronchiectasis registries, the considerable geographic heterogeneity in their etiology. Thus, in socially disadvantaged regions or in those with poorer healthcare access, post-infectious and particularly post-tuberculous forms clearly predominate. It is always necessary to perform the appropriate complementary tests, as highlighted in all bronchiectasis guidelines, to exclude at least the treatable etiologies (treatable trait), since this is undoubtedly associated with a better patient prognosis.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 644-652"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tracheal Laceration by Atypical Blunt Force Trauma: Rampant Gate","authors":"Susana Pipa,&nbsp;Ana Raquel Afonso,&nbsp;Sara Raimundo","doi":"10.1016/j.arbres.2026.02.010","DOIUrl":"10.1016/j.arbres.2026.02.010","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 680-681"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extensive Ground-Glass Nodules With Sequential Responses to the FLAURA2 and MARIPOSA Regimens in EGFR-Mutated NSCLC","authors":"Fumihiro Kashizaki,&nbsp;Ryusuke Orii,&nbsp;Mai Kaneko","doi":"10.1016/j.arbres.2026.03.004","DOIUrl":"10.1016/j.arbres.2026.03.004","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 682-683"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147618272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to: “Reconsidering the Diagnostic Utility of the Six-Biomarker Panel in Pulmonary Rapid Diagnosis Units”","authors":"Antonio Barco-Sánchez,&nbsp;Jaume Trapé","doi":"10.1016/j.arbres.2026.05.012","DOIUrl":"10.1016/j.arbres.2026.05.012","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 672-673"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148275842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CD126+ Central Memory CD8+ T Cells Are Enriched in the Airway in Asthma and Associated With Disease Severity","authors":"Bizhou Li,&nbsp;Xiaolong Ji,&nbsp;Ziyuan Xiang,&nbsp;Fengming Zhao,&nbsp;Haopeng Zhi,&nbsp;Zhangyu Sun,&nbsp;Tao Liu,&nbsp;Yiting Luo,&nbsp;Xiaoying Chen,&nbsp;Rui Feng,&nbsp;Xinhua Tan,&nbsp;Jiayi Chen,&nbsp;Chen Zhan,&nbsp;Ruchong Chen,&nbsp;Yinhuan Li","doi":"10.1016/j.arbres.2026.03.001","DOIUrl":"10.1016/j.arbres.2026.03.001","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 657-660"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147626987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Validation of the RADAR Score in Primary Care: Prognostic Value for Exacerbations and Short-term Changes in Health and Control Status","authors":"Myriam Calle Rubio,&nbsp;Soha Esmaili,&nbsp;Imán Esmaili,&nbsp;Medardo Montenegro,&nbsp;Gianna Vargas Centanaro,&nbsp;Norma Doria Carlin,&nbsp;María Carmen Antón Sanz,&nbsp;Elías Ekech Mesa,&nbsp;José Antonio Fernández Ruiz,&nbsp;Patricia Privado Martínez,&nbsp;Alberto Serrano López de las Hazas,&nbsp;Beatriz Garcia Serrano Jiménez,&nbsp;Juan Luis Rodríguez Hermosa","doi":"10.1016/j.arbres.2026.03.014","DOIUrl":"10.1016/j.arbres.2026.03.014","url":null,"abstract":"<div><h3>Introduction</h3><div>The longitudinal validity of the RADAR score for predicting short-term risk in primary care remains unestablished. We aimed to evaluate its prognostic performance for adverse events and to describe short-term changes in control status and patient-reported health status in a real-world prospective cohort.</div></div><div><h3>Methods</h3><div>In this multicenter study, 706 primary care patients with COPD receiving maintenance triple therapy were assessed at baseline and after a median follow-up of 91 days. We analyzed the association between baseline RADAR control status (≥4 vs &lt;4) and 3-month outcomes (all-cause mortality, severe exacerbations, moderate exacerbations, and composite events). We also described 3-month changes in RADAR score (ΔRADAR) and COPD Assessment Test score (ΔCAT).</div></div><div><h3>Results</h3><div>Baseline poor control (RADAR ≥4) was strongly associated with severe exacerbations (16.2% vs 4.9%; OR, 3.75) and composite events (33.8% vs 22.9%; OR, 1.72). No significant difference was observed for moderate exacerbations (18.0% vs 18.9%). However, when modeled as a frequency count, each 1-point increase in RADAR score was associated with a 21% higher rate of moderate exacerbations (incidence rate ratio, 1.21; 95% CI, 1.15–1.27; <em>P</em> <!-->&lt;<!--> <!-->.001). Patients with RADAR ≥4 exhibited a high-risk profile characterized by worse airflow limitation, active smoking, higher symptom burden, and poorer adherence. Over 3 months, significant changes were observed in the distributions of both ΔCAT and ΔRADAR when analyzed by clinical phenotype and risk level.</div></div><div><h3>Conclusions</h3><div>The RADAR score effectively predicts short-term clinical risk in primary care and provides a practical tool for monitoring COPD and guiding clinical decision-making. It demonstrates significant prognostic value for identifying patients at high short-term risk of severe exacerbations and serves as an initial risk stratification tool to identify individuals requiring further assessment. The observed short-term changes highlight the dynamic nature of COPD control.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 627-634"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147925950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secondary Pulmonary Alveolar Proteinosis Due to MonoMAC Syndrome Associated With a Novel GATA2 Mutation","authors":"Jesús Fernández Francés,&nbsp;Alejandro Vázquez Ramo,&nbsp;Guillermo Calero Rodríguez","doi":"10.1016/j.arbres.2026.04.010","DOIUrl":"10.1016/j.arbres.2026.04.010","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 674-675"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147863511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pneumonitis and Sacituzumab Govitecan: A Case of Metastatic Triple-Negative Breast Cancer","authors":"Jorge Alberto Fong Gutiérrez,&nbsp;Ana Lopez Gonzalez,&nbsp;Javier Juan Garcia","doi":"10.1016/j.arbres.2026.05.003","DOIUrl":"10.1016/j.arbres.2026.05.003","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 676-677"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148004278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ventilator-associated Brain Injury (VABI): Current Understanding","authors":"Thiago Bassi,&nbsp;Martin Dres","doi":"10.1016/j.arbres.2026.04.016","DOIUrl":"10.1016/j.arbres.2026.04.016","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 615-617"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147947683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structured Approach to Mechanical Ventilation and Training Standardization: Multinational Modified Delphi Survey","authors":"Nirmala Manjappachar,&nbsp;Oguz Kilickaya,&nbsp;Kim Duc Chu,&nbsp;Yue Dong,&nbsp;Dimitrios Kantas,&nbsp;Baiyong Wang,&nbsp;Marko Nemet,&nbsp;Ognjen Gajic,&nbsp;Alexander Niven,&nbsp;Richard A. Oeckler,&nbsp;Amos Lal,&nbsp;on behalf of CERTAIN STOP collaborators","doi":"10.1016/j.arbres.2026.03.009","DOIUrl":"10.1016/j.arbres.2026.03.009","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 9","pages":"Pages 665-669"},"PeriodicalIF":8.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147760716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}