Archivos De Bronconeumologia最新文献

{"title":"Pulmonary Metastasis of Malignant Peripheral Nerve Sheath Tumor with Extensive Calcification","authors":"Wei Weng , Xiaoxi Jin , Yaomeng Chen","doi":"10.1016/j.arbres.2025.10.015","DOIUrl":"10.1016/j.arbres.2025.10.015","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 5","pages":"Pages 348-349"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145457490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous Infusion Versus Intermittent Boluses of Cisatracurium in the Early Management of Pediatric Acute Respiratory Distress Syndrome: A Multicenter, Randomized Controlled Trial","authors":"Mohamed K. Talaat ,&nbsp;Hanan M. Ibrahim ,&nbsp;Hebatallah A. Bedair ,&nbsp;Osama M. Ibrahim","doi":"10.1016/j.arbres.2026.02.003","DOIUrl":"10.1016/j.arbres.2026.02.003","url":null,"abstract":"<div><h3>Objectives</h3><div>Pediatric acute respiratory distress syndrome (PARDS) is a critical condition associated with considerable morbidity and mortality. Trials in adults showed controversial results about neuromuscular blocking agents (NMBAs) use in adult acute respiratory distress syndrome. With limited data in PARDS, we sought to compare the outcomes of continuous cisatracurium infusion versus intermittent bolus administration in children with PARDS.</div></div><div><h3>Methods</h3><div>This multicenter randomized controlled study was performed on patients with PARDS. Enrolled patients were categorized into: group I: patients treated with intermittent boluses of cisatracurium and group II: patients treated with intravenous infusion of cisatracurium for 24<!--> <!-->h. The primary outcome was the duration on mechanical ventilator (MV). Additional results included changes in ventilatory parameters, and length of pediatric intensive care unit (PICU) stay.</div></div><div><h3>Results</h3><div>Group II was associated with a significantly higher extubation from MV compared to group I, after accounting for death as a competing event. This association was confined to moderate-to-severe PARDS (subdistribution hazard ratio (SHR) 3.25, 95% CI 1.69–6.25, <em>p</em> <!-->&lt;<!--> <!-->0.001) and not observed in mild PARDS. Similar with earlier PICU discharge, with stronger effect in moderate-to-severe disease (SHR 3.16, 95% CI 1.64–6.11, <em>p</em> <!-->&lt;<!--> <!-->0.001). By day 7, patients with moderate-to-severe PARDS in group II showed lower fraction of inspired oxygen, mean airway pressure, and oxygenation index.</div></div><div><h3>Conclusions</h3><div>In PARDS, cisatracurium infusion was associated with better oxygenation, earlier extubation from MV and shorter PICU stay compared to intermittent boluses, with benefits limited to moderate-to-severe disease. Outcomes were similar in mild PARDS.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 5","pages":"Pages 317-324"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147316153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CO1","authors":"","doi":"10.1016/S0300-2896(26)00127-4","DOIUrl":"10.1016/S0300-2896(26)00127-4","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 5","pages":"Page CO1"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147801776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of 1.1-mm and 1.7-mm Probes in Transbronchial Mediastinal Cryobiopsy: A Randomized Trial","authors":"Ren-Hai Zhong ,&nbsp;Na Wu ,&nbsp;Yi-Ding Li ,&nbsp;Jing Zhang ,&nbsp;Wan-Lei Fu ,&nbsp;Zan-Sheng Huang ,&nbsp;Yu Zhang ,&nbsp;Shuo-Xin Zhang ,&nbsp;Yun-Qiu Jiang ,&nbsp;Yuan-Yuan Yu ,&nbsp;Konstantina Kontogianni ,&nbsp;Felix J.F. Herth ,&nbsp;Ye Fan ,&nbsp;Yan Zhang","doi":"10.1016/j.arbres.2026.01.015","DOIUrl":"10.1016/j.arbres.2026.01.015","url":null,"abstract":"<div><h3>Introduction</h3><div>Recent studies have shown that combined use of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and cryobiopsy provides a higher diagnostic yield for mediastinal lesions as compared with EBUS-TBNA alone. Currently, cryoprobes with diameters of 1.1<!--> <!-->mm and 1.7<!--> <!-->mm have been reported to be used for mediastinal cryobiopsy.</div></div><div><h3>Methods</h3><div>We conducted a randomized controlled trial to evaluate and compare the diagnostic safety and efficacy profile the two cryoprobes in mediastinal disease. Consecutive patients with mediastinal lesions (≥1<!--> <!-->cm in the short axis) were prospectively enrolled. After four passes of needle aspiration, participants underwent mediastinal cryobiopsy with 1.1-mm and 1.7-mm cryoprobes in a randomized order. The main endpoints included procedural success rate, diagnostic yield, and safety.</div></div><div><h3>Results</h3><div>A total of 137 patients were recruited and randomized. Both 1.1-mm and 1.7-mm probe cryobiopsies added diagnostic value to EBUS-TBNA. (94.2% vs 75.9%; <em>p</em> <!-->&lt;<!--> <!-->0.001; 92.0% vs 75.9%; <em>p</em> <!-->&lt;<!--> <!-->0.001; respectively). Supplementing EBUS-TBNA with either 1.1-mm or 1.7-mm probe-cryobiopsy resulted in no differences in overall diagnostic yield (94.2% vs 92.0%; <em>p</em> <!-->=<!--> <!-->0.48). Nevertheless, direct comparison revealed a significantly improved overall diagnostic yield with 1.1-mm cryoprobe relative to 1.7-mm cryoprobe, primarily due to technical failures associated with the latter (88.3% vs 79.6%; <em>p</em> <!-->=<!--> <!-->0.048). Additionally, 1.1-mm and 1.7-mm cryoprobes yielded mediastinal specimens of similar size. Both approaches were safe, with no serious adverse events reported.</div></div><div><h3>Conclusions</h3><div>1.1-mm cryoprobe demonstrates better performance in transbronchial mediastinal cryobiopsy vs 1.7-mm cryoprobe, making it a viable adjunct to traditional needle biopsy.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 5","pages":"Pages 310-316"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147301056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary Hypoplasia and Congenital Dextrocardia Presenting With Hypercapnia in Advanced Age","authors":"Mónica Matute-Villacís ,&nbsp;Macarena Lovera ,&nbsp;Adriana Martín Pascual","doi":"10.1016/j.arbres.2025.11.013","DOIUrl":"10.1016/j.arbres.2025.11.013","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 5","pages":"Pages 354-355"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145899145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pneumoconiosis Associated With Occupational Exposure to Calcium Stearate: First Case With Mineralogical Confirmation","authors":"Marina Acebo Castro,&nbsp;Juan Diego Álvarez Mavárez","doi":"10.1016/j.arbres.2025.11.008","DOIUrl":"10.1016/j.arbres.2025.11.008","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 5","pages":"Pages 346-347"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145803190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Persistence of Indocyanine Green One Week After Percutaneous Injection into Pulmonary Nodules","authors":"Miguel J. Arrarás Martínez ,&nbsp;Karol de Aguiar Quevedo ,&nbsp;Maria Barrios Benito","doi":"10.1016/j.arbres.2025.10.014","DOIUrl":"10.1016/j.arbres.2025.10.014","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 5","pages":"Pages 344-345"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145457426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary Venous Anatomical Variation: V6 and Middle Lobe Vein Forming an Independent Trunk","authors":"Álvaro Fuentes-Martín ,&nbsp;Natalia Cenci Nizzo ,&nbsp;Ángel Cilleruelo Ramos","doi":"10.1016/j.arbres.2025.10.019","DOIUrl":"10.1016/j.arbres.2025.10.019","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 5","pages":"Pages 352-353"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145522724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nintedanib Combined With Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis or Progressive Pulmonary Fibrosis: A Long-Term Retrospective Multicentre Study (Combi-PF)","authors":"Corentin Meersseman ,&nbsp;Elisa Martínez Besteiro ,&nbsp;Nicolas Romain-Scelle ,&nbsp;Bruno Crestani ,&nbsp;Sylvain Marchand-Adam ,&nbsp;Hilario Nunes ,&nbsp;Lidwine Wémeau-Stervinou ,&nbsp;Raphael Borie ,&nbsp;Rémi Diesler ,&nbsp;Claudia Valenzuela ,&nbsp;Vincent Cottin ,&nbsp;OrphaLung network","doi":"10.1016/j.arbres.2025.10.004","DOIUrl":"10.1016/j.arbres.2025.10.004","url":null,"abstract":"<div><h3>Background</h3><div>Antifibrotic therapy only reduces disease progression in patients with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF), highlighting the need for more effective therapeutic strategies. Whether combining nintedanib and pirfenidone is safe and tolerable in real-world setting is poorly known.</div></div><div><h3>Methods</h3><div>We conducted a multicentre, retrospective study of patients with IPF or PPF who had received a combination of nintedanib and pirfenidone and primarily assessed safety and tolerability. Secondary objectives included assessment of dose reduction, treatment cessation, survival, and lung function outcomes.</div></div><div><h3>Results</h3><div>We included 38 patients (84.2% with IPF) who received combination therapy between 2014 and 2024. Adverse drug reactions occurred in 84.2% of patients (severe in 28.9%): weight loss (52.6%), diarrhoea (36.8%), abdominal pain (28.9%). Dose was reduced in 28.9% of patients, and combination was discontinued in 26.3%. Median follow-up was 17.4 months; the median duration of combination therapy was 12.8 months. The rate of decline in FVC decreased from −26.7 before the initiation of the combination to −11.1<!--> <!-->mL/months during combination therapy. The median survival from diagnosis was 28.5 months, with a 5-yr survival of 21.7%. Among patients listed for lung transplantation, 11 (52.4%) underwent transplantation, of whom 6 had continued the combination until the transplantation.</div></div><div><h3>Conclusion</h3><div>Although no new safety signal arose, combination therapy is challenging in real-world setting due to poor tolerability especially weight loss. It can nevertheless be a viable treatment option in some patients, particularly as a bridge to lung transplantation. Further studies are needed to confirm the efficacy of this combined therapeutic strategy.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 5","pages":"Pages 301-309"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145386332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combination Therapy in Pulmonary Fibrosis: A New Era","authors":"Fabrizio Luppi ,&nbsp;Giovanni Ferrara ,&nbsp;Carlo Vancheri","doi":"10.1016/j.arbres.2026.01.012","DOIUrl":"10.1016/j.arbres.2026.01.012","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 5","pages":"Pages 287-288"},"PeriodicalIF":9.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}