{"title":"Mask-Type Switching Trajectories and CPAP Use in Long-Term Obstructive Sleep Apnoea: The SwitchAdene Real-World Cohort Study.","authors":"Celia Vidal, Jean-Pierre Mallet, Raphaël Gilson, Olivier Gaubert, Jean-Christian Borel, Frédéric Gagnadoux, Arnaud Prigent, Arnaud Bourdin, Nicolas Molinari, Dany Jaffuel","doi":"10.1016/j.arbres.2026.07.008","DOIUrl":"10.1016/j.arbres.2026.07.008","url":null,"abstract":"<p><strong>Objective: </strong>To characterise long-term mask-type trajectories among patients receiving continuous positive airway pressure (CPAP) and assess their associations with CPAP nonadherence and treatment termination.</p><p><strong>Methods: </strong>This real-world longitudinal cohort study included newly diagnosed adults treated with CPAP for more than 1 month. Patients had unrestricted access to 48 models across 4 mask types: nasal masks (NMs), oronasal masks (ONMs), and nasal-pillow masks (NPMs), with the latter subdivided into nasal-cradle masks (NCMs) and intranasal masks (INMs). Sequence analysis was used to identify mask trajectories, and multivariable models were used to estimate odds ratios (ORs) for CPAP nonadherence and treatment termination.</p><p><strong>Results: </strong>Among 4675 patients, the median duration of CPAP treatment was 1.5 years (IQR, 0.7-2.8 years); 21.8% were nonadherent, and 26.1% terminated treatment. Adherent patients changed mask type less frequently than nonadherent patients and those who terminated treatment (43.7% vs 50.4% and 53.8%, respectively; p<.001). NM use decreased from 72.3% to 43.1%, whereas ONM use increased from 19.8% to 37.0%, INM use from 2.4% to 6.5%, and NCM use from 5.5% to 13.4%. Fifteen trajectories were identified. Compared with NM renewal, ONM and INM renewal were not associated with a higher risk of nonadherence or treatment termination, whereas NCM renewal was associated with CPAP termination (OR, 1.60; 95%CI, 1.04-2.47; p=.034). Switching from an initial NM to an INM (OR, 1.68; 95%CI, 1.18-2.39; p=.004), NCM (OR, 1.76; 95%CI, 1.26-2.45; p=.001), or ONM (OR, 1.31; 95%CI, 1.01-1.70; p=.046) was associated with CPAP termination.</p><p><strong>Conclusions: </strong>In routine clinical practice, NM, ONM, and INM renewal trajectories were comparable, whereas NCM renewal was associated with unfavourable outcomes. Switching from an NM to an ONM or NPM was associated with poorer CPAP use. NCMs and INMs should not be pooled under the general NPM category.</p><p><strong>Trial registration: </strong>The SwitchAdene study is registered with the Health Data Hub under registration No. 19334378.</p>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148719843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ignacio Boira, Néstor Rodríguez-Melean, Leticia De Las Vecillas, David Romero, Ana Noblejas, Andrea Trisán, Violeta Esteban-Ronda, Elena Villamañán, Javier Dominguez-Ortega, Luis Gómez-Carrera, Ignacio Robles-Barrena, Santiago Quirce, Rodolfo Álvarez-Sala, Eusebi Chiner, Daniel Laorden
{"title":"Early Mepolizumab Plus Glucocorticoids in Newly Diagnosed Eosinophilic Granulomatosis With Polyangiitis: A 52-Week Multicenter Retrospective Cohort Study.","authors":"Ignacio Boira, Néstor Rodríguez-Melean, Leticia De Las Vecillas, David Romero, Ana Noblejas, Andrea Trisán, Violeta Esteban-Ronda, Elena Villamañán, Javier Dominguez-Ortega, Luis Gómez-Carrera, Ignacio Robles-Barrena, Santiago Quirce, Rodolfo Álvarez-Sala, Eusebi Chiner, Daniel Laorden","doi":"10.1016/j.arbres.2026.07.012","DOIUrl":"10.1016/j.arbres.2026.07.012","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148719814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Isolated Exertional Hypoxaemia in Pulmonary Fibrosis: A Complex Story Without a Satisfying Ending.","authors":"Anne E Holland, Yet H Khor","doi":"10.1016/j.arbres.2026.07.013","DOIUrl":"https://doi.org/10.1016/j.arbres.2026.07.013","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148688522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Carlos Gasca Aldama, Karen Harumi López Rodriguez, Osvaldo Alexis Marche Fernández
{"title":"Venous Excess Ultrasound in Acute Pulmonary Embolism Reflects Right Ventricular Uncoupling Rather Than Congestion.","authors":"José Carlos Gasca Aldama, Karen Harumi López Rodriguez, Osvaldo Alexis Marche Fernández","doi":"10.1016/j.arbres.2026.07.003","DOIUrl":"https://doi.org/10.1016/j.arbres.2026.07.003","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148668174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Belén Picazos Pérez, Tomás Sabater Fajardo, Raquel López Reyes
{"title":"Sheehan Syndrome as a Hidden Cause of Postpartum Clinical Deterioration in Severe Idiopathic Pulmonary Arterial Hypertension.","authors":"María Belén Picazos Pérez, Tomás Sabater Fajardo, Raquel López Reyes","doi":"10.1016/j.arbres.2026.07.005","DOIUrl":"https://doi.org/10.1016/j.arbres.2026.07.005","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148668181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utility of Z Scores for Defining Progressive Pulmonary Fibrosis in Interstitial Lung Disease","authors":"Aimé Alarcón-Dionet, Mauricio González-Garcia, Ricardo Villafuerte, Emily Rincón-Alvarez, Moises Selman, Ivette Buendia-Roldan","doi":"10.1016/j.arbres.2026.01.021","DOIUrl":"10.1016/j.arbres.2026.01.021","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 8","pages":"Pages 589-592"},"PeriodicalIF":8.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146224895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria João Oliveira, Mafalda Pais, Pedro Viegas, Leonor Roseta, Carla Nogueira, Sara Conde, Ana Machado, Carla Ribeiro
{"title":"Assessment of Quality of Life at the End of Life in Patients Undergoing Home Mechanical Ventilation","authors":"Maria João Oliveira, Mafalda Pais, Pedro Viegas, Leonor Roseta, Carla Nogueira, Sara Conde, Ana Machado, Carla Ribeiro","doi":"10.1016/j.arbres.2026.01.017","DOIUrl":"10.1016/j.arbres.2026.01.017","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 8","pages":"Pages 583-585"},"PeriodicalIF":8.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorine E. Hartman, Selina Caspar Anthony, Karin Klooster, Dirk-Jan Slebos
{"title":"Minimal Important Difference of FEV1 and FVC in COPD Patients Undergoing Bronchoscopic Lung Volume Reduction","authors":"Jorine E. Hartman, Selina Caspar Anthony, Karin Klooster, Dirk-Jan Slebos","doi":"10.1016/j.arbres.2026.04.003","DOIUrl":"10.1016/j.arbres.2026.04.003","url":null,"abstract":"<div><h3>Objectives</h3><div>Spirometry is essential for the diagnosis, severity assessment and longitudinal monitoring of Chronic Obstructive Pulmonary Disease (COPD). However, the minimal important difference (MID) for key spirometric parameters such as forced expiratory volume in one second (FEV<sub>1</sub>) and forced vital capacity (FVC) remains poorly defined, particularly in patients with severe COPD. This study aimed was to determine the MID for FEV<sub>1</sub> and FVC in patients with severe COPD undergoing bronchoscopic lung volume reduction treatment.</div></div><div><h3>Methods</h3><div>We retrospectively analyzed data from patients with severe COPD who underwent bronchoscopic lung volume reduction between 2009 and 2024 at the University Medical Center Groningen. Anchor-based methods were used to calculate the MID for FEV<sub>1</sub> and FVC using the 6-minute walk distance and St. George's Respiratory Questionnaire (SGRQ) as anchors.</div></div><div><h3>Results</h3><div>A total of 543 patients with severe COPD were included, predominantly female (68%) with a mean age of 62<!--> <!-->±<!--> <!-->8 years and baseline FEV<sub>1</sub> of 27%<!--> <!-->±<!--> <!-->8 predicted. Anchor-based analyses yielded MIDs of approximately 139<!--> <!-->mL (relative: 19%) for FEV<sub>1</sub> and 349<!--> <!-->mL (16%) for FVC at 6 months, and 127<!--> <!-->mL (17%) for FEV<sub>1</sub> and 379<!--> <!-->mL (17%) for FVC at 12 months.</div></div><div><h3>Conclusions</h3><div>The overall estimated MID for FEV<sub>1</sub> in our population of patients with severe emphysema was 133<!--> <!-->mL (18%) and for FVC 364<!--> <!-->mL (16%). While the MID should not be interpreted as a strict cut-off, consensus on its values is essential to facilitate comparability across studies and to guide appropriate sample size calculations. Validation of these estimates in other COPD populations would be valuable.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"62 8","pages":"Pages 542-547"},"PeriodicalIF":8.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147863452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}