Archivos De Bronconeumologia最新文献

{"title":"Changes in the Functional Classification of Spirometry Using the New Interpretation Standard 2022: A Multicenter Study","authors":"Santiago C. Arce ,&nbsp;Carlos Aguirre-Franco ,&nbsp;Patricia Schonffeldt-Guerrero ,&nbsp;Cecilia Rodríguez-Flores ,&nbsp;Laura Gochicoa-Rangel","doi":"10.1016/j.arbres.2024.07.005","DOIUrl":"10.1016/j.arbres.2024.07.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Pulmonary function tests are vital for diagnosing lung diseases, assessing treatment responses, and monitoring respiratory health. Recent updates to interpretive standards by the European Respiratory and American Thoracic Societies (ERS/ATS) in 2022 introduced significant changes compared to the 2005 standards. They include incorporating lung volume measurements, non-specific and mixed disorders, introducing <em>z</em>-scores for functional abnormality assessment, reducing severity categories from five to three, and revising criteria for positive bronchodilator responses.</div></div><div><h3>Methods</h3><div>We conducted a retrospective, multi-center study across four centers using spirometric data spanning from 2002 to 2022. We categorized spirometry results using both the 2005 and 2022 ATS/ERS standards and calculated predicted values following the GLI 2012 equation (Caucasian subset).</div></div><div><h3>Results</h3><div>Among 79,039 subjects, we observed that 23% shifted from an obstructive diagnosis under the 2005 standard to a mixed pattern diagnosis under the 2022 standard, necessitating lung volume assessments. In the evaluation of bronchodilator responses among 59,203 tests, 12.3% of those initially classified as responders were reclassified as non-responders with the new standards. We found variations in severity categorization across age groups, with older patients tending to receive milder severity classifications and younger individuals receiving greater severity classifications under the 2022 standards.</div></div><div><h3>Conclusions</h3><div>The 2022 document emphasizes early lung volume assessment, potentially leading to increased utilization of more complex tests. Furthermore, the bronchodilator response was predominant in extreme age groups and among individuals with milder spirometric impairments. This shift may impact treatment decisions, potentially initiating medication in milder cases and de-escalating treatment in more severe cases.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 76-81"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141700843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Thoracic Complication of an Abdominal Procedure: Massive Hemothorax Following Percutaneous Transhepatic Portal Vein Angioplasty","authors":"Luis Gorospe ,&nbsp;Rut Romera-Sánchez ,&nbsp;Gemma María Muñoz-Molina","doi":"10.1016/j.arbres.2024.10.016","DOIUrl":"10.1016/j.arbres.2024.10.016","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 122-123"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative Proteomics Analysis of Serum and Urine With DIA Mass Spectrometry Reveals Biomarkers for Pediatric Obstructive Sleep Apnea","authors":"Yunxiao Wu ,&nbsp;Mansheng Li ,&nbsp;Kai Zhang ,&nbsp;Jie Ma ,&nbsp;David Gozal ,&nbsp;Yunping Zhu ,&nbsp;Zhifei Xu","doi":"10.1016/j.arbres.2024.06.017","DOIUrl":"10.1016/j.arbres.2024.06.017","url":null,"abstract":"<div><h3>Objectives</h3><div>Identification of suitable biomarkers that facilitate the screening and evaluation of pediatric obstructive sleep apnea (OSA) and its severity was explored.</div></div><div><h3>Methods</h3><div><span>Data-independent acquisition quantitative proteomic<span> analysis was employed to identify serum and urine proteins with differential expression patterns between children with OSA and controls. Differentially expressed proteins that gradually increased or decreased with the severity of OSA were retained as potential biomarkers and underwent </span></span>ELISA validation.</div></div><div><h3>Results</h3><div><span>We found that with increasing severity of OSA, there was a gradual upregulation of 34 proteins in the serum and 124 proteins in the urine, along with a respective downregulation<span><span><span> of 10 serum proteins and 64 </span>urinary proteins in the initial cohort of 40 children. These proteins primarily participate in immune activation, the complement pathway, oxygen transport, and reactive oxygen metabolism. Notably, </span>cathepsin Z<span> exhibited a positive correlation with the obstructive apnea hypopnea index, whereas sex hormone-binding globulin (SHBG) was negatively correlated. These proteins were then validated by ELISA in an independent cohort (</span></span></span><em>n</em> <!-->=<!--> <span>21). Circulating cathepsin Z and SHBG levels displayed acceptable diagnostic performance of OSA with AUC values of 0.863 and 0.738, respectively.</span></div></div><div><h3>Conclusions</h3><div>We identified two promising circulating proteins as novel biomarkers for clinical diagnosis and assessment of pediatric OSA severity. Furthermore, the comprehensive proteomic profile in pediatric OSA should aid in exploring the underlying pathophysiological mechanisms associated with this prevalent condition.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 67-75"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141698539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The New Tobacco Companies Offensive: The Nicotine Pouches","authors":"José Ignacio de Granda-Orive ,&nbsp;Carlos A. Jiménez-Ruiz ,&nbsp;Mina Gaga","doi":"10.1016/j.arbres.2024.10.017","DOIUrl":"10.1016/j.arbres.2024.10.017","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 65-66"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individual and Structural Factors Influencing Participation to Low-Dose Computed Tomography Screening in a Chinese Centralized Lung Cancer Screening Cohort","authors":"Shenglin Zhao ,&nbsp;Bibo Li ,&nbsp;Zhikai Yu ,&nbsp;Jia Du ,&nbsp;Hong Zhou ,&nbsp;Mei He","doi":"10.1016/j.arbres.2024.09.009","DOIUrl":"10.1016/j.arbres.2024.09.009","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 96-100"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary Hamartoma With Rare Imaging Features","authors":"Xu-ping Chen ,&nbsp;Xiao-Dong Yang ,&nbsp;Shi-xu He","doi":"10.1016/j.arbres.2024.09.015","DOIUrl":"10.1016/j.arbres.2024.09.015","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Page 119"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silicone-induced Lymphadenopathy Mimicking Metastatic Lung Cancer","authors":"Sara González-Castro ,&nbsp;Natalia Cadavid-Fernández ,&nbsp;Luis Gorospe Sarasúa","doi":"10.1016/j.arbres.2024.10.013","DOIUrl":"10.1016/j.arbres.2024.10.013","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 120-121"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of PIKO-6® and COPD-6® Devices in COPD Screening","authors":"Miguel A. Hernández-Mezquita ,&nbsp;Idania de los Santos-Ventura ,&nbsp;Vanesa Hidalgo-Sierra ,&nbsp;Alfonso Pérez-Trullen ,&nbsp;Enrique Barrueco-Otero","doi":"10.1016/j.arbres.2024.10.002","DOIUrl":"10.1016/j.arbres.2024.10.002","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 110-112"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Five-Repetition Sit-to-Stand Test as Predictor of Mortality in High Risk COPD Patients","authors":"Roberto Bernabeu-Mora ,&nbsp;Elisa Valera-Novella ,&nbsp;Elodia Teresa Bernabeu-Serrano ,&nbsp;Juan José Soler-Cataluña ,&nbsp;Myriam Calle-Rubio ,&nbsp;Francesc Medina-Mirapeix","doi":"10.1016/j.arbres.2024.07.026","DOIUrl":"10.1016/j.arbres.2024.07.026","url":null,"abstract":"<div><h3>Objective</h3><div>To determine if adding performance on the five-repetition sit-to-stand test (5-STS) to chronic obstructive pulmonary disease (COPD) high-risk criteria, proposed by the Spanish COPD guidelines (GesEPOC), affects mortality prognosis.</div></div><div><h3>Methods</h3><div>Observational study of COPD outpatients involved prospective follow-up for 5 years. Patients were classified based on 5-STS performance and risk criteria proposed by GesEPOC version 2021. Outcome measures were 5-year mortality timing and rate. Kaplan–Meier curves and univariate and multivariate Cox proportional-hazard analyses, analysis of variance, and univariate and multivariate linear and logistic regression models were used.</div></div><div><h3>Results</h3><div>One hundred and thirty-seven patients were included. Mean age was 66<!--> <!-->±<!--> <!-->8.3 years, and 87.6% were men. Of them, 115 (83.9%) were classified as high risk, 43 (34.4%) of whom had poor performance on the 5-STS. Overall mortality at 5 years was 27% and was significantly higher in the high-risk (29.6%) compared with the low-risk (13.6%) group. Among high-risk patients, mortality at 5 years was significantly worse with poor 5-STS performance (60.5%) compared with non-poor performance (11.1%). Poor performance on the 5-STS was independently associated with increased 5-year mortality risk (HR 4.70; 95% CI: 1.96–11.27) in a model adjusted for history of heart disease and dyspnea.</div></div><div><h3>Conclusion</h3><div>Among high-risk COPD patients, those with poor performance on the 5-STS have a significantly higher mortality at 5 years than those with non-poor 5-STS performance.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 90-95"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142153065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Nomogram for Genetic Risk of PAH","authors":"Alejandro Cruz-Utrilla ,&nbsp;Fernando Vargas-Ursúa ,&nbsp;Alberto Fernández-Villar ,&nbsp;Pilar Escribano-Subías","doi":"10.1016/j.arbres.2024.10.001","DOIUrl":"10.1016/j.arbres.2024.10.001","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 107-109"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}