Archivos De Bronconeumologia最新文献

{"title":"Venlafaxine-Induced Eosinophilic Pleural Effusion and Peripheral Eosinophilia: First Reported Case and the Role of an SNRI.","authors":"Matilde Ferreira de Almeida, Inês Estalagem, Carlos Couto","doi":"10.1016/j.arbres.2025.02.018","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.02.018","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Out With the Old, in With the New: What Changes in the 9th Edition of the TNM Classification for Lung Cancer?","authors":"Ramón Rami-Porta, Hisao Asamura, Valerie W Rusch","doi":"10.1016/j.arbres.2025.02.016","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.02.016","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Where are we With Home-Based Noninvasive Mechanical Ventilation and How Can we Go Further?","authors":"Léo Grassion, Jesús González-Bermejo","doi":"10.1016/j.arbres.2025.03.002","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.03.002","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catheter-Protected Cryobiopsy of a Peripheral Nodule Using Linear Endobronchial Ultrasound.","authors":"Iker Fernández-Navamuel Basozabal, Borja Recalde Zamacona, Andrés Giménez Velando, Javier Alfayate Sánchez, Javier Flandes Aldeyturriaga","doi":"10.1016/j.arbres.2025.02.017","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.02.017","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reassessing the Landscape of Viral Respiratory Infections After the COVID-19 Pandemic","authors":"Elena Generali , Stefano Aliberti , Maurizio Cecconi , Antonio Voza","doi":"10.1016/j.arbres.2024.11.005","DOIUrl":"10.1016/j.arbres.2024.11.005","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 3","pages":"Pages 125-126"},"PeriodicalIF":8.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The COPD Kaleidoscope: Breaking Bad Dogmatic Recommendations","authors":"Juan Marco Figueira-Gonçalves , José Luis Lopez-Campos","doi":"10.1016/j.arbres.2024.11.010","DOIUrl":"10.1016/j.arbres.2024.11.010","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 3","pages":"Pages 127-128"},"PeriodicalIF":8.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resectable Non-Small Cell Lung Cancer Heterogeneity and Recurrence Assessed by Tissue Next-Generation Sequencing Genotyping and Circulating Tumor Cell EZH2 Characterization","authors":"Abel Garcia-Diaz ,&nbsp;María José Moyano-Rodríguez ,&nbsp;María del Carmen Garrido-Navas ,&nbsp;Diego de Miguel-Perez ,&nbsp;Jose Expósito-Hernández ,&nbsp;Bernardino Alcázar-Navarrete ,&nbsp;Francisco Ortuño ,&nbsp;David Landeira ,&nbsp;Pedro J. Romero ,&nbsp;Adrian Garcia-Moreno ,&nbsp;Jose A. Lorente ,&nbsp;Javier Lopez-Hidalgo ,&nbsp;Clara Bayarri-Lara ,&nbsp;Maria Jose Serrano","doi":"10.1016/j.arbres.2024.08.006","DOIUrl":"10.1016/j.arbres.2024.08.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Non-small cell lung cancer (NSCLC) is the most common type of lung neoplasm. Despite surgical resection, it has a high relapse rate, accounting for 30–55% of all cases. Next-generation sequencing (NGS) based on a customized gene panel and the analysis of circulating tumor cells (CTCs) can help identify heterogeneity, stratify high-risk patients, and guide treatment decisions. In this descriptive study involving a small prospective cohort, we focus on the phenotypic characterization of CTCs, particularly concerning EZH2 expression (a member of the Polycomb Repression Complex 2), as well as on the mutation profiles of the tissue using a customized gene panel and their association with poor outcomes in NSCLC.</div></div><div><h3>Methods</h3><div>Isolation and characterization of EZH2 on CTCs were evaluated before surgical resection (CTC1) and one month after surgery (CTC2) in resectable NSCLC patients. Targeted NGS was performed using a customized 50-gene panel on tissue samples from a subset of patients.</div></div><div><h3>Results</h3><div>76 patients with resectable NSCLC were recruited. The top mutated genes in the cohort included <em>TP53</em>, <em>FLT1</em>, <em>MUC5AC</em>, <em>EGFR</em>, and <em>NLRP3</em>. Pair of genes that had mutually exclusive mutations was <em>TP53-RIN3</em>, and pairs of genes with co-occurring mutations were <em>CD163-TLR4</em>, <em>FGF10-FOXP2</em>, <em>ADAMTSL3-FLT1</em>, <em>ADAMTSL3-MUC5AC</em> and <em>MUC5AC-NLRP3</em>. CTCs decreased significantly between the two time points CTC1 and CTC2 (<em>p</em> <!-->&lt;<!--> <!-->0.0001), and CTCs+ patients with high EZH2 expression had an 87% increased risk of death (<em>p</em> <!-->=<!--> <!-->0.018).</div></div><div><h3>Conclusions</h3><div>Integrating molecular profiling of tumors and CTC characterization can provide valuable insights into tumor heterogeneity and improve patient stratification for resectable NSCLC.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 3","pages":"Pages 156-165"},"PeriodicalIF":8.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of an In-Hospital Motivational Programme on Physical Activity Levels of Individuals with Chronic Heart Failure or Chronic Obstructive Pulmonary Disease Undergoing Rehabilitation: A Randomized Controlled Trial","authors":"Michele Vitacca ,&nbsp;Mara Paneroni ,&nbsp;Emanuela Zanelli ,&nbsp;Beatrice Salvi ,&nbsp;Gloria Fiorini Aloisi ,&nbsp;Nicolino Ambrosino ,&nbsp;Simonetta Scalvini","doi":"10.1016/j.arbres.2024.11.008","DOIUrl":"10.1016/j.arbres.2024.11.008","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 3","pages":"Pages 173-175"},"PeriodicalIF":8.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Obstructive Sleep Apnea on Subclinical Target Organ Damage in Patients With Resistant Hypertension","authors":"Mireia Dalmases ,&nbsp;Manuel Sánchez-de-la-Torre ,&nbsp;Dolores Martinez ,&nbsp;Olga Minguez ,&nbsp;Rafaela Vaca ,&nbsp;Lydia Pascual ,&nbsp;Maria Aguilá ,&nbsp;Esther Gracia-Lavedan ,&nbsp;Ivan D. Benitez ,&nbsp;Lucía Pinilla ,&nbsp;Anunciación Cortijo ,&nbsp;Clara Gort-Paniello ,&nbsp;Ramon Bascompte Claret ,&nbsp;Miguel Ángel Martinez-Garcia ,&nbsp;Olga Mediano ,&nbsp;Sofía Romero Peralta ,&nbsp;Ana Maria Fortuna-Gutierrez ,&nbsp;Paola Ponte Marquez ,&nbsp;Luciano F. Drager ,&nbsp;Mayara Cabrini ,&nbsp;Gerard Torres","doi":"10.1016/j.arbres.2024.07.018","DOIUrl":"10.1016/j.arbres.2024.07.018","url":null,"abstract":"<div><h3>Introduction</h3><div>Among all patients with hypertension, those with resistant hypertension (RH) have the highest rates of subclinical organ damage (SOD). The prevalence of obstructive sleep apnea (OSA) is high in RH patients, and it could contribute to SOD. We aimed to investigate how OSA and its treatment are related to SOD in a large cohort of RH patients.</div></div><div><h3>Methods</h3><div>This is an ancillary analysis to the SARAH study, a multicentre observational cohort aiming to evaluate the impact of OSA on RH. Individuals with RH who were undergoing a sleep study and have information on at least one of the SOD variables (vascular, cardiac or renal damage) were selected. Patients were followed-up for three years.</div></div><div><h3>Results</h3><div>In total, 503 subjects were included. The participants were predominantly male, obese, and the median (IQR) apnea–hypopnea index (AHI) was 15.5 (7.90–31.5)<!--> <!-->events/h. No differences in the presence of vascular or cardiac damage were observed between OSA and non-OSA patients. A lower estimated glomerular filtration rate (eGFR) was observed in participants with OSA than in those without OSA, with an adjusted effect of −8.69<!--> <!-->mL/min/1.73<!--> <!-->m² (−13.59, −3.79; <em>p</em> value<!--> <!-->&lt;<!--> <!-->0.001). Kidney damage was also greater in subjects with OSA, with an adjusted OR (95% CI) of 1.77 (1.09, 2.87; <em>p</em> value<!--> <!-->=<!--> <!-->0.02). The eGFR showed a linear dose–response relationship with OSA severity. Among patients treated with CPAP, lower eGFR values were observed in noncompliant subjects.</div></div><div><h3>Conclusions</h3><div>OSA could contribute to worsening renal function in patients with RH. No compliance with CPAP was associated with lower values of eGFR.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 3","pages":"Pages 147-155"},"PeriodicalIF":8.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary EBV+ DLBCL in the Trachea","authors":"Yong Chen ,&nbsp;Peng Chen ,&nbsp;Shanping Huang ,&nbsp;Gang Li ,&nbsp;Shenbo Fu ,&nbsp;Rong Yang","doi":"10.1016/j.arbres.2024.11.007","DOIUrl":"10.1016/j.arbres.2024.11.007","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 3","pages":"Pages 184-185"},"PeriodicalIF":8.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}