Laura Beaudoin, Maximiliano Ferraris, Leticia Pacheco Hernández, Alejandro Balestracci
{"title":"Extended versus standard corticosteroid treatment in primary nephrotic syndrome onset.","authors":"Laura Beaudoin, Maximiliano Ferraris, Leticia Pacheco Hernández, Alejandro Balestracci","doi":"10.5546/aap.2024-10534.eng","DOIUrl":"10.5546/aap.2024-10534.eng","url":null,"abstract":"<p><p>Introduction. The standard treatment for the onset of primary nephrotic syndrome (PNS) consists of 8 weeks of prednisone. Alternatively, it was postulated that extending treatment to 12 weeks is associated with fewer relapses. We aimed to evaluate whether relapses' cumulative incidence (CI) at 2 years was lower with extended treatment. Population and methods. This is a retrospective cohort study of patients with PNS who were followed for 2 years and grouped according to the initial treatment received. Results. Thirty-seven patients were included per regimen. The time to first relapse was similar (p = 0.63), and the CI of relapses at 2 years was 75.6% with standard treatment and 72.9% (p = 0.79) with extended treatment; relative risk was 0.96 (95%CI 0.73-1.26). Relapse-free survival in the 2 years of follow-up was also similar (log-rank test = 0.51). Conclusion. Relapse CI at 2 years was similar with both treatment regimens.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410534"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Venezuela´s migrant children.","authors":"Fernando Ferrero","doi":"10.5546/aap.2024-10567.eng","DOIUrl":"10.5546/aap.2024-10567.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410567"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Foreign bodies in the gastrointestinal tract of children: A clinical analysis and guidelines for management.","authors":"Qin Chen, Lei Song, Yan-Mei Yang","doi":"10.5546/aap.2024-10475.eng","DOIUrl":"10.5546/aap.2024-10475.eng","url":null,"abstract":"<p><p>Objective: In this paper, we analyzed the outcomes of foreign bodies in the digestive tract of 42 children who were hospitalized in the pediatric department of a tertiary hospital in a medium-sized city in China. The focus is on discussing the indications for removal of foreign bodies via digestive endoscopy. Methods: Forty-two children with foreign bodies in the digestive tract, hospitalized from June 2020 to October 2022 were selected. Results: (1) The majority of the children (52.4%) who had coins in their digestive tracts were between the ages of 3 to 6 years. (2) Symptoms were most commonly observed in the esophagus (62.5%), and gastroscopy was used to remove all foreign bodies. (3) There were 13 cases with foreign bodies in the stomach, and only 4 required removal of the foreign bodies. (4) Among 4 cases where imaging was unable to detect the foreign bodies, gastroscopy revealed the foreign bodies in the esophagi of 2 symptomatic cases, and were removed; the other 2 asymptomatic cases excreted the foreign bodies in the stools. Conclusion: The timing for foreign body removal via digestive endoscopy depends on factors such as location, nature, and symptoms. Single foreign bodies that migrate within the stomach and intestine may be observed without intervention if asymptomatic. Sharp foreign bodies usually pass spontaneously if beyond the esophagus. Emergency gastroscopy is recommended for symptomatic cases; otherwise, clinical observation is suggested.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410475"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Cohen Arazi, Patricia G Suárez, Susana Villa Nova, Victoria Laporta, Daniel A Díaz Sandoval, Kathya A Rojas Jaramillo
{"title":"Urticaria multiforme in school age: A case report.","authors":"Laura Cohen Arazi, Patricia G Suárez, Susana Villa Nova, Victoria Laporta, Daniel A Díaz Sandoval, Kathya A Rojas Jaramillo","doi":"10.5546/aap.2024-10442.eng","DOIUrl":"10.5546/aap.2024-10442.eng","url":null,"abstract":"<p><p>Urticaria multiforme is an allergic hypersensitivity reaction. It manifests as a skin reaction with a vascular response pattern in the dermis. Urticaria multiforme is a benign, self-limited condition of unknown etiology, with onset in pediatric age and a more frequent range of presentation in children from 4 months to 4 years old. It is considered a subtype of urticaria in which the skin lesion corresponds to particular annular and polycyclic wheals, with a purple center and evanescent nature, frequently associated with acral edema and fever. The clinical recognition of urticaria multiforme, together with an adequate symptomatology, are sufficient for the diagnosis and provide peace of mind to parents. The most important differential diagnoses include acute urticaria, urticarial vasculitis, and erythema multiforme. The objectives of this article are to train pediatricians in recognizing urticaria multiforme and the differential diagnoses and to highlight the importance of symptomatology in reaching a diagnosis.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410442"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142131691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tuberculosis in children and adolescents: diagnostic criteria and treatment.","authors":"Norma E González","doi":"10.5546/aap.2024-10498.eng","DOIUrl":"10.5546/aap.2024-10498.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410498"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María S Ciruzzi, Gisela M Delmonte, Estela Di Cola, Verónica Dussel, Eugenia Ensabella, Karina V Gómez, Ma Fernanda Marchetti, Fernanda Peserico, Jimena Saldeña, Estela M Torrecilla
{"title":"[Consensus on therapeutic effort limitation, with a palliative care approach].","authors":"María S Ciruzzi, Gisela M Delmonte, Estela Di Cola, Verónica Dussel, Eugenia Ensabella, Karina V Gómez, Ma Fernanda Marchetti, Fernanda Peserico, Jimena Saldeña, Estela M Torrecilla","doi":"10.5546/aap.2024-10491","DOIUrl":"10.5546/aap.2024-10491","url":null,"abstract":"<p><p>The National Committee for Palliative Care expressed their commitment to approach the decision of foregoing life sustaining treatment from a palliative care perspective, allowing the implementation of a care program to prevent therapeutic obstinacy, respect the dignity of the patient and their parents, and evaluate a rational, reasonable and adequate use of health and technological resources by focusing on the quality of life of the child, in order to realize their best interest, providing a guide that facilitates the decision-making process in dilemmatic situations in pediatrics.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410491"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142131689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complex glycerol kinase deficiency: A case report.","authors":"Mauro Islas Abdenur","doi":"10.5546/aap.2024-10354.eng","DOIUrl":"10.5546/aap.2024-10354.eng","url":null,"abstract":"<p><p>Glycerol kinase deficiency is a rare X-linked genetic disorder, which may be associated with adrenal hypoplasia congenita and Duchenne muscular dystrophy. Here we describe a complex pediatric case of adrenal insufficiency with persistent hyponatremia and hyperkalemia despite an adequate management with corticosteroids, hypertriglyceridemia since birth, and chronic malnutrition in nutritional recovery. No cases have been reported in the Argentine literature, which increases the relevance of this case in pediatric clinical practice due to its unusual presentation.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410354"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Digital detoxification: An urgent need for teen well-being.","authors":"Fernando Lamas, Martín Saban","doi":"10.5546/aap.2024-10574.eng","DOIUrl":"10.5546/aap.2024-10574.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410574"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142754448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Feller, Deborah De Guevara, Viviana Herzovich, Noelia Dujovne, Marta Ciaccio, Natalia Gazek
{"title":"Intrathyroidal neurofibroma, a case report.","authors":"Ana Feller, Deborah De Guevara, Viviana Herzovich, Noelia Dujovne, Marta Ciaccio, Natalia Gazek","doi":"10.5546/aap.2024-10460.eng","DOIUrl":"10.5546/aap.2024-10460.eng","url":null,"abstract":"<p><p>Neurofibromatosis type 1 (NF1) is the most common neurocutaneous disease. It is characterized by café-au-lait spots, melanocytic hamartomas of the iris, pseudo-freckles, neurofibromas, and tumor predisposition. The presence of neurofibromas in the thyroid gland is extremely rare. Here we present the case of a 6-year-old male patient with NF1 who consulted at the Department of Endocrinology due to a thyroid tumor and whose ultrasound confirmed a heterogeneous mass at the posterior level of the right lobe. A cervical surgery found the tumor was adhered to the larynx and trachea, with the recurrent laryngeal nerve entering the tumor. Due to the impossibility of dissection, a right hemithyroidectomy was performed and the pathological examination confirmed the presence of plexiform neurofibroma and intrathyroidal neurofibroma. This is the second case reported in childhood and the youngest case to date. Neurofibroma with thyroid involvement should be suspected in patients with cervical mass and NF1, since diagnostic guidance allows avoiding unnecessary studies and guide treatment.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410460"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guillermina Chattás, María Maluenda, Amalia Holmberg, Lucila Scotto, Belén Madero, Calvin Steel, Damasia Sánchez De Bustamante, Inés Vivot, Zaira Nuñez Olmos, María V Brunelli
{"title":"Use of neonatal active humidification: an observational study in high complexity maternity wards.","authors":"Guillermina Chattás, María Maluenda, Amalia Holmberg, Lucila Scotto, Belén Madero, Calvin Steel, Damasia Sánchez De Bustamante, Inés Vivot, Zaira Nuñez Olmos, María V Brunelli","doi":"10.5546/aap.2024-10482.eng","DOIUrl":"10.5546/aap.2024-10482.eng","url":null,"abstract":"<p><p>Introduction. Active humidification treatment in incubators effectively reduces risks related to loss of barrier function in preterm infants. However, no conclusive evidence exists on the criteria for active humidification care. This study aimed to describe active humidification in incubators in newborn infants under 32 weeks in high-complexity public maternity hospitals in Argentina. Methods. An observational and cross-sectional study in supervisors of 68 neonatal intensive care units (NICU) in 2023, using a digital survey, designed ad hoc, anonymous, and voluntary, with four dimensions (sociodemographic variables, humidification criteria, nursing care, and humidity decrease, and withdrawal criteria) and 35 questions. Results. Sixty-four responses were obtained (94%); 84.3% of the NICUs use humidity in the incubators, ranging between 80-90% relative humidity; 57.8% use it, considering the gestational age. The average active humidification time was 11 days. During this period, 84.4% did not perform skin-to-skin contact. The patient's clinical condition was used in 35.9% as a criterion for withdrawal; 30% did not perceive any risk associated with the treatment, and although 48.4% identified a risk of infection, no measures were implemented to reduce it. Conclusions. The findings of this study show great variability in the criteria for initiation, duration, and withdrawal of active humidification in incubators in newborns younger than 32 weeks.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410482"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142754452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}