Jorge R Ferraris, Rosario Luxardo, Alfredo M Eymann, Martina Turano, Soledad Crucelegui, Guillermo Rosa-Diez
{"title":"Quality of life and social characteristics of young adults in chronic hemodialysis with pediatric-onset renal disease.","authors":"Jorge R Ferraris, Rosario Luxardo, Alfredo M Eymann, Martina Turano, Soledad Crucelegui, Guillermo Rosa-Diez","doi":"10.5546/aap.2024-10555.eng","DOIUrl":"10.5546/aap.2024-10555.eng","url":null,"abstract":"<p><p>Introduction. Health-related quality of life (HRQL) and its social consequences have not been evaluated in adults who started renal replacement therapy (RRT) in childhood/adolescence and are currently on hemodialysis. Population and methods. We compared 26 patients who started their RRT at <18 years with a group that started their RRT at 18 years or more. We studied social variables and HRQL with the KDQOL-36 questionnaire. Scores >50 indicate good HRQL. Results. The study was conducted in 2018. The scores were: physical health: 55 and 58.1; mental health: 61.2 and 66.7; disease burden: 39.2 and 37.3; symptoms and problems: 75.6 and 78.5; effects: 65.9 and 51.6 (p < 0.019) for those who started RRT at pediatric age or adult age respectively. Socioeconomic status and education were similar in both groups. Fifty percent of the patients with RRT from pediatric age and 38.5% of those who started with RRT in adulthood were unemployed. In the group who started RRT at pediatric age, 61.5% lived with their parents vs. 19% of those who started RRT in adulthood; 11.5% of the patients with RRT at pediatric age had a partner vs. 42.3% of those who started RRT as adults. Conclusions. Adults with the onset of RRT in childhood who are currently on hemodialysis have a good perception of HRQL, superior to adults with a recent onset of RRT. They have a good education, but their lack of work, independent living, and having a partner is related to the burden of illness.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410555"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guillermo G Barrenechea, Rocío Sánchez, Leonardo S Bastos
{"title":"Impact of single-dose varicella vaccination in Argentina, by province: a time series study.","authors":"Guillermo G Barrenechea, Rocío Sánchez, Leonardo S Bastos","doi":"10.5546/aap.2024-10412.eng","DOIUrl":"10.5546/aap.2024-10412.eng","url":null,"abstract":"<p><p>Introduction. Argentina implemented the varicella vaccine in 2015. This study aimed to evaluate the impact of vaccine implementation in each province of Argentina. Materials and methods. An observational, ecological analytic study using secondary data sources. We performed a time series description of varicella cases and built generalized additive models using a negative binomial distribution. We modeled the behavior of varicella in the period 2005-2014 and made a forecast of the most likely behavior until 2019. We assessed the impact by comparing expected and observed incidence rates. We studied whether 2015 was a turning point in the incidence trend in each jurisdiction. We used R and Joinpoint software. Results. Between 2005 and 2019, Argentina had an incidence rate of varicella of 5.93 cases/100,000 population. At the national level, the incidence rate significantly decreased after 2015. In Argentina in general and in 6 provinces, 2015 was a breakpoint, whereas in the rest of the provinces, it occurred before (n = 2) or after (n = 1), or there was none in the time series analyzed (n = 15). Conclusions. The work demonstrates the impact of vaccine implementation in each of Argentina's provinces and highlights the importance of evaluating national policies at the provincial level.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410412"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Beaudoin, Maximiliano Ferraris, Leticia Pacheco Hernández, Alejandro Balestracci
{"title":"Extended versus standard corticosteroid treatment in primary nephrotic syndrome onset.","authors":"Laura Beaudoin, Maximiliano Ferraris, Leticia Pacheco Hernández, Alejandro Balestracci","doi":"10.5546/aap.2024-10534.eng","DOIUrl":"10.5546/aap.2024-10534.eng","url":null,"abstract":"<p><p>Introduction. The standard treatment for the onset of primary nephrotic syndrome (PNS) consists of 8 weeks of prednisone. Alternatively, it was postulated that extending treatment to 12 weeks is associated with fewer relapses. We aimed to evaluate whether relapses' cumulative incidence (CI) at 2 years was lower with extended treatment. Population and methods. This is a retrospective cohort study of patients with PNS who were followed for 2 years and grouped according to the initial treatment received. Results. Thirty-seven patients were included per regimen. The time to first relapse was similar (p = 0.63), and the CI of relapses at 2 years was 75.6% with standard treatment and 72.9% (p = 0.79) with extended treatment; relative risk was 0.96 (95%CI 0.73-1.26). Relapse-free survival in the 2 years of follow-up was also similar (log-rank test = 0.51). Conclusion. Relapse CI at 2 years was similar with both treatment regimens.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410534"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Foreign bodies in the gastrointestinal tract of children: A clinical analysis and guidelines for management.","authors":"Qin Chen, Lei Song, Yan-Mei Yang","doi":"10.5546/aap.2024-10475.eng","DOIUrl":"10.5546/aap.2024-10475.eng","url":null,"abstract":"<p><p>Objective: In this paper, we analyzed the outcomes of foreign bodies in the digestive tract of 42 children who were hospitalized in the pediatric department of a tertiary hospital in a medium-sized city in China. The focus is on discussing the indications for removal of foreign bodies via digestive endoscopy. Methods: Forty-two children with foreign bodies in the digestive tract, hospitalized from June 2020 to October 2022 were selected. Results: (1) The majority of the children (52.4%) who had coins in their digestive tracts were between the ages of 3 to 6 years. (2) Symptoms were most commonly observed in the esophagus (62.5%), and gastroscopy was used to remove all foreign bodies. (3) There were 13 cases with foreign bodies in the stomach, and only 4 required removal of the foreign bodies. (4) Among 4 cases where imaging was unable to detect the foreign bodies, gastroscopy revealed the foreign bodies in the esophagi of 2 symptomatic cases, and were removed; the other 2 asymptomatic cases excreted the foreign bodies in the stools. Conclusion: The timing for foreign body removal via digestive endoscopy depends on factors such as location, nature, and symptoms. Single foreign bodies that migrate within the stomach and intestine may be observed without intervention if asymptomatic. Sharp foreign bodies usually pass spontaneously if beyond the esophagus. Emergency gastroscopy is recommended for symptomatic cases; otherwise, clinical observation is suggested.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410475"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Cohen Arazi, Patricia G Suárez, Susana Villa Nova, Victoria Laporta, Daniel A Díaz Sandoval, Kathya A Rojas Jaramillo
{"title":"Urticaria multiforme in school age: A case report.","authors":"Laura Cohen Arazi, Patricia G Suárez, Susana Villa Nova, Victoria Laporta, Daniel A Díaz Sandoval, Kathya A Rojas Jaramillo","doi":"10.5546/aap.2024-10442.eng","DOIUrl":"10.5546/aap.2024-10442.eng","url":null,"abstract":"<p><p>Urticaria multiforme is an allergic hypersensitivity reaction. It manifests as a skin reaction with a vascular response pattern in the dermis. Urticaria multiforme is a benign, self-limited condition of unknown etiology, with onset in pediatric age and a more frequent range of presentation in children from 4 months to 4 years old. It is considered a subtype of urticaria in which the skin lesion corresponds to particular annular and polycyclic wheals, with a purple center and evanescent nature, frequently associated with acral edema and fever. The clinical recognition of urticaria multiforme, together with an adequate symptomatology, are sufficient for the diagnosis and provide peace of mind to parents. The most important differential diagnoses include acute urticaria, urticarial vasculitis, and erythema multiforme. The objectives of this article are to train pediatricians in recognizing urticaria multiforme and the differential diagnoses and to highlight the importance of symptomatology in reaching a diagnosis.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410442"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142131691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Venezuela´s migrant children.","authors":"Fernando Ferrero","doi":"10.5546/aap.2024-10567.eng","DOIUrl":"10.5546/aap.2024-10567.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410567"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tuberculosis in children and adolescents: diagnostic criteria and treatment.","authors":"Norma E González","doi":"10.5546/aap.2024-10498.eng","DOIUrl":"10.5546/aap.2024-10498.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410498"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María S Ciruzzi, Gisela M Delmonte, Estela Di Cola, Verónica Dussel, Eugenia Ensabella, Karina V Gómez, Ma Fernanda Marchetti, Fernanda Peserico, Jimena Saldeña, Estela M Torrecilla
{"title":"[Consensus on therapeutic effort limitation, with a palliative care approach].","authors":"María S Ciruzzi, Gisela M Delmonte, Estela Di Cola, Verónica Dussel, Eugenia Ensabella, Karina V Gómez, Ma Fernanda Marchetti, Fernanda Peserico, Jimena Saldeña, Estela M Torrecilla","doi":"10.5546/aap.2024-10491","DOIUrl":"10.5546/aap.2024-10491","url":null,"abstract":"<p><p>The National Committee for Palliative Care expressed their commitment to approach the decision of foregoing life sustaining treatment from a palliative care perspective, allowing the implementation of a care program to prevent therapeutic obstinacy, respect the dignity of the patient and their parents, and evaluate a rational, reasonable and adequate use of health and technological resources by focusing on the quality of life of the child, in order to realize their best interest, providing a guide that facilitates the decision-making process in dilemmatic situations in pediatrics.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410491"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142131689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complex glycerol kinase deficiency: A case report.","authors":"Mauro Islas Abdenur","doi":"10.5546/aap.2024-10354.eng","DOIUrl":"10.5546/aap.2024-10354.eng","url":null,"abstract":"<p><p>Glycerol kinase deficiency is a rare X-linked genetic disorder, which may be associated with adrenal hypoplasia congenita and Duchenne muscular dystrophy. Here we describe a complex pediatric case of adrenal insufficiency with persistent hyponatremia and hyperkalemia despite an adequate management with corticosteroids, hypertriglyceridemia since birth, and chronic malnutrition in nutritional recovery. No cases have been reported in the Argentine literature, which increases the relevance of this case in pediatric clinical practice due to its unusual presentation.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410354"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Feller, Deborah De Guevara, Viviana Herzovich, Noelia Dujovne, Marta Ciaccio, Natalia Gazek
{"title":"Intrathyroidal neurofibroma, a case report.","authors":"Ana Feller, Deborah De Guevara, Viviana Herzovich, Noelia Dujovne, Marta Ciaccio, Natalia Gazek","doi":"10.5546/aap.2024-10460.eng","DOIUrl":"10.5546/aap.2024-10460.eng","url":null,"abstract":"<p><p>Neurofibromatosis type 1 (NF1) is the most common neurocutaneous disease. It is characterized by café-au-lait spots, melanocytic hamartomas of the iris, pseudo-freckles, neurofibromas, and tumor predisposition. The presence of neurofibromas in the thyroid gland is extremely rare. Here we present the case of a 6-year-old male patient with NF1 who consulted at the Department of Endocrinology due to a thyroid tumor and whose ultrasound confirmed a heterogeneous mass at the posterior level of the right lobe. A cervical surgery found the tumor was adhered to the larynx and trachea, with the recurrent laryngeal nerve entering the tumor. Due to the impossibility of dissection, a right hemithyroidectomy was performed and the pathological examination confirmed the presence of plexiform neurofibroma and intrathyroidal neurofibroma. This is the second case reported in childhood and the youngest case to date. Neurofibroma with thyroid involvement should be suspected in patients with cervical mass and NF1, since diagnostic guidance allows avoiding unnecessary studies and guide treatment.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410460"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}