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School violence: An oxymoron. 校园暴力：一种矛盾修辞法。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-06-25 DOI: 10.5546/aap.2026-11166.eng
María S Ciruzzi
{"title":"School violence: An oxymoron.","authors":"María S Ciruzzi","doi":"10.5546/aap.2026-11166.eng","DOIUrl":"https://doi.org/10.5546/aap.2026-11166.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202611166"},"PeriodicalIF":0.5,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148300331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bean syndrome in childhood: Use of sirolimus in a severe case. 儿童豆豆综合征：西罗莫司在严重病例中的应用。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-06-18 DOI: 10.5546/aap.2025-10937.eng
Nadia Dell, Nicolás Affranchino, Laura Busquet, Fernanda Conde, Carla Vaccaro, María V Ponce, Jesica Ciavatta, Jordana Tartara
{"title":"Bean syndrome in childhood: Use of sirolimus in a severe case.","authors":"Nadia Dell, Nicolás Affranchino, Laura Busquet, Fernanda Conde, Carla Vaccaro, María V Ponce, Jesica Ciavatta, Jordana Tartara","doi":"10.5546/aap.2025-10937.eng","DOIUrl":"https://doi.org/10.5546/aap.2025-10937.eng","url":null,"abstract":"<p><p>Bean syndrome, also known as blue rubber bleb nevus syndrome, is a rare congenital disorder characterized by multiple venous malformations affecting the skin, soft tissues, and gastrointestinal tract. Its main complication is chronic gastrointestinal bleeding, which can lead to iron-deficiency anemia and a lower quality of life. We present the case of a pediatric patient diagnosed with Bean syndrome, in whom typical skin lesions and gastrointestinal involvement were identified. We describe the clinical course, the diagnostic tests performed, and the treatment regimen initiated with sirolimus. This case highlights the importance of recognizing this condition in children for early diagnosis and timely treatment, as well as the need for multidisciplinary follow-up. Sirolimus represents a promising therapeutic option for severe cases, although it requires close monitoring.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510937"},"PeriodicalIF":0.5,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148263212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geleophysical dysplasia associated with FBN1 variants and phenotypic variability: A case series in Argentine children. 与FBN1变异和表型变异相关的血管物理发育不良：阿根廷儿童的病例系列。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-06-11 DOI: 10.5546/aap.2025-10995.eng
Sofía L Melgarejo, Rosario Ramos Mejía, Mayra Arbelo, Victoria Huckstad, Mariana Del Pino
{"title":"Geleophysical dysplasia associated with FBN1 variants and phenotypic variability: A case series in Argentine children.","authors":"Sofía L Melgarejo, Rosario Ramos Mejía, Mayra Arbelo, Victoria Huckstad, Mariana Del Pino","doi":"10.5546/aap.2025-10995.eng","DOIUrl":"https://doi.org/10.5546/aap.2025-10995.eng","url":null,"abstract":"<p><p>Geleophysical skeletal dysplasia is an extremely rare condition characterized by predominantly acral skeletal involvement with a progressive course, associated with short stature and short limbs. Skin, joint, and organ involvement have been described; cardiorespiratory involvement is fatal. It is inherited in an autosomal dominant or recessive manner and is associated with variants in genes encoding extracellular matrix proteins: ADAMTSL2, LTBP3, and FBN1. This article describes a series of children with FBN1-associated geleophysical dysplasia who were followed up at a pediatric hospital. All presented with severe short stature and short limbs. Radiological findings were consistent in the hands (brachymetacarpal and brachyphalangeal features, notches in the metacarpals, and delayed ossification of the carpus). There was variability in severity and organ involvement indicators. Given the complexity of the condition and the multiple systems involved, there is a need for recommendations regarding a multidisciplinary approach throughout life and the importance of genetic counseling.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510995"},"PeriodicalIF":0.5,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148203804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health-related quality of life in children and adolescents with myelomeningocele: A cross-sectional study. 儿童和青少年脊髓脊膜膨出患者的健康相关生活质量：一项横断面研究
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-06-11 DOI: 10.5546/aap.2025-10931.eng
Clara Meyer, Lucía Pérez, Marcelina Carretero, Santiago Portillo, Cristina Cortines
{"title":"Health-related quality of life in children and adolescents with myelomeningocele: A cross-sectional study.","authors":"Clara Meyer, Lucía Pérez, Marcelina Carretero, Santiago Portillo, Cristina Cortines","doi":"10.5546/aap.2025-10931.eng","DOIUrl":"https://doi.org/10.5546/aap.2025-10931.eng","url":null,"abstract":"<p><p>Introduction. Myelomeningocele (MMC) is the most severe form of neural tube defects, characterized by physical, cognitive, and social sequelae. Despite advances in treatment, its impact on health-related quality of life (HRQoL) remains significant. In Argentina, no studies have been found that assess HRQoL in this population using locally validated tools. Objective. To assess lung function in children and adolescents with MMC and compare it with that of a healthy control group matched for age and sex.Population and methods. An observational, analytical, cross-sectional study was conducted between December 2023 and December 2024. Patients aged 2 to 18 years were included at a tertiary care hospital. The PedsQL™ 4.0 generic version (proxy-report) questionnaire, validated in Argentina, was used to assess physical, emotional, social, and academic aspects in both sick and healthy children. Results. The study included 68 children with MMC and 68 controls (median age: 9 years). The total PedsQL score was significantly lower in the MMC group compared with the controls (median 65.8 vs. 82.2; p <0.001). The greatest differences were observed in the physical domain (median 56.3 vs. 96.9; p <0.001); emotional functioning showed a smaller difference (median 70 vs. 80; p<0.01). No differences in the HRQoL were observed between patients with or without prenatal surgery, ventriculoperitoneal shunt, or intermittent clean catheterization.Conclusion. The study found that children with MMC have significantly lower HRQoL scores compared to their healthy peers.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510931"},"PeriodicalIF":0.5,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148203848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epstein-Barr virus-associated thymic lymphoepithelial carcinoma in a child. 儿童爱泼斯坦-巴尔病毒相关胸腺淋巴上皮癌
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-06-04 DOI: 10.5546/aap.2025-11002.eng
Marlene M Sepich, María L Herrera Andino, Alejandra A Cano, Ana V Sánchez, Carlos H Hollmann
{"title":"Epstein-Barr virus-associated thymic lymphoepithelial carcinoma in a child.","authors":"Marlene M Sepich, María L Herrera Andino, Alejandra A Cano, Ana V Sánchez, Carlos H Hollmann","doi":"10.5546/aap.2025-11002.eng","DOIUrl":"https://doi.org/10.5546/aap.2025-11002.eng","url":null,"abstract":"<p><p>Thymic lymphoepithelial carcinoma is a rare neoplasm in children, with histological features similar to those of nasopharyngeal carcinoma and a frequent association with the Epstein-Barr virus (EBV). Diagnosis is challenging due to clinical and imaging overlaps with lymphomas and mediastinal germ cell tumors. We present the case of a 12-year-old patient with a mediastinal mass, supraclavicular lymphadenopathy, and pulmonary metastases, histologically diagnosed as EBV-positive thymic lymphoepithelial carcinoma. He received chemotherapy with cisplatin and gemcitabine, immunotherapy with pembrolizumab, and radiation therapy, and achieved complete remission. The literature reports few pediatric cases, with a poor prognosis and a median survival of less than 24 months. However, the addition of anti-PD-1 immunotherapy in EBV-positive tumors appears to offer clinical benefit. This case highlights the importance of a multidisciplinary approach and the potential benefits of combination therapies, including immunotherapy, in EBV-positive mediastinal tumors in children.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202511002"},"PeriodicalIF":0.5,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148148335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dishonest behavior in biomedical journals: analysis of two cases and reflections on their detection. 生物医学期刊失信行为：两例分析及侦查思考。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-06-01 Epub Date: 2026-03-26 DOI: 10.5546/aap.2025-10813.eng
Alfredo Eymann, Mariana Rapoport, Daniel Matusevich
{"title":"Dishonest behavior in biomedical journals: analysis of two cases and reflections on their detection.","authors":"Alfredo Eymann, Mariana Rapoport, Daniel Matusevich","doi":"10.5546/aap.2025-10813.eng","DOIUrl":"10.5546/aap.2025-10813.eng","url":null,"abstract":"<p><p>Introduction. Scientific dishonesty is a persistent, increasingly sophisticated phenomenon that poses a growing challenge for editorial work in biomedical journals. Objectives. To describe the process of detecting fraudulent publication of articles submitted to a scientific journal in health sciences during 2024. Methods. A retrospective observational documentary study was conducted. All original manuscripts received during 2024 by a scientific journal in health sciences were included. Each text was evaluated using the Similarity Check software and analyzed by the editorial committee in accordance with the Committee on Publication Ethics (COPE) criteria. Results. Of the 71 manuscripts evaluated, two cases of fraud were identified. The first corresponded to duplicate publication by the same author; the second, to covert plagiarism by translation from another author. In both cases, the manuscripts were rejected, the authors were notified, and the right of reply was offered, which was not satisfactory. Conclusion. Two attempts at fraudulent publication were documented in 2024, detected using similarity tools and confirmed by editorial analysis.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510813"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147503077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception of vaccine myths in daily clinical practice: A survey of healthcare professionals. 在日常临床实践中对疫苗的误解：一项对卫生保健专业人员的调查。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-06-01 Epub Date: 2026-02-19 DOI: 10.5546/aap.2025-10921.eng
Vanesa E Castellano, Mariela Del Pino, Sofía Diana Menéndez, Pablo Bonvehí, Fernando Fernández, Fernando Burgos, Mirtha Valdeolmillos, Romina Gigliotti, Mariano Díaz
{"title":"Perception of vaccine myths in daily clinical practice: A survey of healthcare professionals.","authors":"Vanesa E Castellano, Mariela Del Pino, Sofía Diana Menéndez, Pablo Bonvehí, Fernando Fernández, Fernando Burgos, Mirtha Valdeolmillos, Romina Gigliotti, Mariano Díaz","doi":"10.5546/aap.2025-10921.eng","DOIUrl":"10.5546/aap.2025-10921.eng","url":null,"abstract":"<p><p>Introduction. Misinformation is a barrier to immunization. The objective was to describe and categorize vaccine-related myths reported by healthcare professionals (HCPs). Population and methods. A descriptive, retrospective study was conducted using a survey administered during registration for a vaccine symposium, in which HCPs were invited to identify myths they had encountered in their practice. The open-ended responses were classified into their main categories and themes and synthesized using artificial intelligence. Results. A total of 679 HCPs responses were recorded; 751 myths were mentioned. Main categories: harm (46.2%), vaccine-specific myths (20.9%), and false contraindications (16.1%). Most frequent topics: \"they cause autism\" (23.0%), \"they are harmful\" (22.5%), \"the flu vaccine causes the flu\" (15.2%). Conclusion. The main myths were related to harm, and autism remains the most frequent myth. Communication tools are essential for daily practice.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510921"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146193989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Esophageal lung in a 4-month-old infant. 4个月婴儿食管肺。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-06-01 Epub Date: 2026-01-22 DOI: 10.5546/aap.2025-10796.eng
Carlos Giuseppucci, Ramiro Ortiz, Luciano Korman, María S Canestrari, Juliana Lostra, María C Castro Coria, Daniela Quirós, Camila Marossero, Luciana Cotignola, Verónica Giubergia
{"title":"Esophageal lung in a 4-month-old infant.","authors":"Carlos Giuseppucci, Ramiro Ortiz, Luciano Korman, María S Canestrari, Juliana Lostra, María C Castro Coria, Daniela Quirós, Camila Marossero, Luciana Cotignola, Verónica Giubergia","doi":"10.5546/aap.2025-10796.eng","DOIUrl":"10.5546/aap.2025-10796.eng","url":null,"abstract":"<p><p>Esophageal lung is an extremely rare congenital malformation characterized by an abnormal connection between the esophagus and the bronchial tree, without communication with the airway. We present the case of a 4-month-old female patient who was admitted to the hospital with a diagnosis of pneumonia. Complementary studies confirmed the presumptive diagnosis of esophageal lung. Surgical treatment was then decided upon, and a pneumonectomy with esophageal repair was performed. The patient progressed favorably.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510796"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perspectives on Neonatology in the context of global declining birth rates. 全球出生率下降背景下的新生儿学展望。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-06-01 Epub Date: 2026-03-05 DOI: 10.5546/aap.2025-10957.eng
Jorge L Alvarado Socarras, Erika J Vallejo López
{"title":"Perspectives on Neonatology in the context of global declining birth rates.","authors":"Jorge L Alvarado Socarras, Erika J Vallejo López","doi":"10.5546/aap.2025-10957.eng","DOIUrl":"10.5546/aap.2025-10957.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510957"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147343452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brain abscess caused by Mycobacterium avium complex in an adolescent with an inborn error of immunity. 由鸟分枝杆菌复合体引起的先天性免疫错误的青少年脑脓肿。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-06-01 Epub Date: 2025-12-26 DOI: 10.5546/aap.2025-10852.eng
Manuel Feuerstein, Luciana Santelli, Carolina Garrigue, María C Gonçalves Neiva Novo, Gabriela Manonelles, Andrea Gómez Raccio, Isabel Squassi
{"title":"Brain abscess caused by Mycobacterium avium complex in an adolescent with an inborn error of immunity.","authors":"Manuel Feuerstein, Luciana Santelli, Carolina Garrigue, María C Gonçalves Neiva Novo, Gabriela Manonelles, Andrea Gómez Raccio, Isabel Squassi","doi":"10.5546/aap.2025-10852.eng","DOIUrl":"10.5546/aap.2025-10852.eng","url":null,"abstract":"<p><p>Mycobacterium avium complex (MAC) infections of the central nervous system are rare and represent a diagnostic challenge, especially in immunocompromised patients. Comprehensive management requires early diagnosis, prolonged antimicrobial treatment, and, in some cases, neurosurgical interventions. We present the case of a 16-year-old patient with an inborn error of immunity caused by a variant in the NFKB1A gene, who consulted for paresis of the left upper limb. A diagnosis of brain abscess was made using central nervous system (CNS) imaging, and the etiological agent was confirmed by neurosurgical biopsy culture after an unfavorable clinical course with initial empirical treatment. The patient was treated with rifampicin, ethambutol, levofloxacin, linezolid, clarithromycin, and high-dose dexamethasone, achieving significant clinical and radiological improvement after prolonged treatment.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510852"},"PeriodicalIF":0.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145809306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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