Archivos argentinos de pediatria最新文献_第4页

IF 0.5 4区医学

Archivos argentinos de pediatria Pub Date : 2025-09-18 DOI: 10.5546/aap.2025-10819.eng

Paulo Cáceres Guido, Julieta González

引用次数: 0

Evaluation of the effectiveness of the respiratory syncytial virus vaccine in children under 6 months of age in Córdoba, Argentina. 阿根廷Córdoba 6个月以下儿童呼吸道合胞病毒疫苗有效性评价。

IF 0.5 4区医学

Archivos argentinos de pediatria Pub Date : 2025-09-18 DOI: 10.5546/aap.2025-10741.eng

Graciela F Scruzzi, Carlos G Franchini, Ana C Giorgetti, Lautaro Fonseca Ingüe, Daiana D Sarmiento, Sandra M Belfiore, Ana P Willington, Fernando Canna, María E Vittori, Sonia Nieva, Gustavo J Klein

{"title":"Evaluation of the effectiveness of the respiratory syncytial virus vaccine in children under 6 months of age in Córdoba, Argentina.","authors":"Graciela F Scruzzi, Carlos G Franchini, Ana C Giorgetti, Lautaro Fonseca Ingüe, Daiana D Sarmiento, Sandra M Belfiore, Ana P Willington, Fernando Canna, María E Vittori, Sonia Nieva, Gustavo J Klein","doi":"10.5546/aap.2025-10741.eng","DOIUrl":"https://doi.org/10.5546/aap.2025-10741.eng","url":null,"abstract":"ntroduction. The recently approved vaccine against respiratory syncytial virus (RSV) is administered to pregnant women and confers immunity to their babies; however, the evaluation of its effectiveness is limited. Objective. To evaluate the effectiveness of the vaccine against hospitalization due to RSV in children under 6 months of age during the vaccination campaign for pregnant women. Population and methods. Case-control study nested in a cohort of newborns whose mothers were indicated for RSV vaccination in Córdoba, Argentina. We included 180 cases with positive laboratory results for RSV and 1,069 asymptomatic controls who attended routine check-ups. Multiple logistic regression models were performed considering the presence of RSV as the primary response variable, adjusted for maternal age, gestational age, birth weight, maternal influenza vaccination, maternal education level, and multiple births. Vaccine effectiveness was calculated using the formula EV = (1 - OR) × 100. Results. The RSV vaccine reduces the likelihood of becoming ill with RSV by 74.0% (OR: 0.26; CI: 0.170.39); the influenza vaccine reduces it by 70% (OR: 0.30; CI: 0.21-0.43). For each completed week of gestational age, protection against the disease increases by 10% (OR: 0.90; CI: 0.81-0.99). Conclusion. The vaccine is effective against hospitalization due to RSV in children under 6 months of age, who are the most vulnerable population, and could be an essential tool for reducing morbidity and mortality due to RSV.","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510741"},"PeriodicalIF":0.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From the beginning to 2023; did the COVID-19 pandemic affect the anxiety of parents and preschool children equally over the time? 从开始到2023年；在这段时间里，COVID-19大流行对父母和学龄前儿童焦虑的影响是否相同？

IF 0.5 4区医学

Archivos argentinos de pediatria Pub Date : 2025-09-18 DOI: 10.5546/aap.2025-10768.eng

Şenay Türe, Sevtap Velipaşaoğlu

{"title":"From the beginning to 2023; did the COVID-19 pandemic affect the anxiety of parents and preschool children equally over the time?","authors":"Şenay Türe, Sevtap Velipaşaoğlu","doi":"10.5546/aap.2025-10768.eng","DOIUrl":"https://doi.org/10.5546/aap.2025-10768.eng","url":null,"abstract":"Background. The COVID-19 pandemic is perceived as a major threat to health and the economy worldwide, and its effects have been ongoing for about five years. Studies were generally conducted in the early stages of the pandemic, and usually included adults or adolescents. Studies examining the impact of the pandemic on preschool children (3-6 years old) are quite scarce. This study aimed to evaluate the perceived anxiety levels of children aged 3 to 6 years and their parents, focusing on anxiety-related behavioral patterns in children and the frequency of anxiety-related expressions. The assessment was conducted at four distinct time points over four years following the onset of the COVID-19 pandemic. Method. This descriptive-cross-sectional study was conducted between May 17, 2020 and October 30, 2023. An online questionnaire form was used at four different time points. Results. 3732 parents with children aged 3-6 participated in the study. Children's anxiety-related behaviors and expressions were more frequent during the first and second time points. Anxiety-related behaviors were more common in children during the long-term bans. Conclusion. Perceived anxiety levels of the children aged 3-6 years at different time points during COVID-19 pandemic reflected the epidemic trends of the disease and parental anxiety levels. Understanding how the effects are distributed is important for the future.","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510768"},"PeriodicalIF":0.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment-associated posterior reversible encephalopathy syndrome in an adolescent with Crohn's disease: A case report. 青春期克罗恩病治疗相关的后部可逆性脑病综合征：一例报告

IF 0.5 4区医学

Archivos argentinos de pediatria Pub Date : 2025-09-18 DOI: 10.5546/aap.2025-10654.eng

Manuel Feuerstein, Micaela Salas Victoria, Cynthia Slaifstein, Estanislao Díaz Pumará

引用次数: 0

Processes applied to the manufacture of infant formulas and foods for special medical purposes. 用于生产婴儿配方奶粉和特殊医疗用途食品的工艺。

IF 0.5 4区医学

Archivos argentinos de pediatria Pub Date : 2025-09-18 DOI: 10.5546/aap.2025-10755.eng

Diana Kabbache, Natalia V Ratti, Silvina Tasat, Gabriel Vinderola

引用次数: 0

Refractory multisystem Langerhans cell histiocytosis in an infant: use of vemurafenib as a therapeutic option. 婴儿难治性多系统朗格汉斯细胞组织细胞增多症：使用vemurafenib作为治疗选择。

IF 0.5 4区医学

Archivos argentinos de pediatria Pub Date : 2025-09-18 DOI: 10.5546/aap.2025-10774.eng

M Victoria Tata, M Natalia Mantero, Laura Caristia, Tatiana Alfaro, Mercedes Morici, Gisela Venialgo, Patricia Della Giovanna

引用次数: 0

Examinations (OSCEs) for Medical School Graduation: A Comparison of the borderline and Hofstee methods. 医学院校毕业考试：边界法与霍夫斯蒂法之比较。

IF 0.5 4区医学

Archivos argentinos de pediatria Pub Date : 2025-08-28 DOI: 10.5546/aap.2025-10758.eng

Marcelo R García Diéguez, Marta P Del Valle, Alejandro G Cragno

{"title":"Examinations (OSCEs) for Medical School Graduation: A Comparison of the borderline and Hofstee methods.","authors":"Marcelo R García Diéguez, Marta P Del Valle, Alejandro G Cragno","doi":"10.5546/aap.2025-10758.eng","DOIUrl":"https://doi.org/10.5546/aap.2025-10758.eng","url":null,"abstract":"Introduction. Setting the cut-off point in objective structured clinical examinations (OSCEs) is a controversial aspect of assessment. In resource-limited settings, the Hofstee method requires additional tasks from other teachers outside the examination time. In contrast, the borderline group method is applied during the assessment, allowing for a more efficient use of time and resources. Objective. To compare the reliability of the borderline group and Hofstee methods applied in a graduation OSCE at an Argentine public university, providing local evidence to an internationally relevant debate. Population and methods. Cross-sectional study of 56 students in a 12-station OSCE. Two standardsetting methods were applied: borderline group (using observers during the exam) and Hofstee (electronic consultation with expert judges). Cut-off points, failure rates, and reliability (phi coefficient λ) were compared using generalizability theory. Results. The average score was 66.1 (SD 4.7). The cut-off point using the borderline group method was 54 (overall) with a reliability of 0.89 and no failures. The Hofstee method defined cut-off points of 60.7 (overall), with 3 and 1 students failing, respectively, and reliability of 0.68 and 0.82. Conclusions. Both methods show adequate reliability; however, they differ in their practical consequences, as the borderline group method was more lenient, generating a higher number of passing students.","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510758"},"PeriodicalIF":0.5,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144940477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The continued relevance of monoclonal antibodies. 单克隆抗体的持续相关性。

IF 0.5 4区医学

Archivos argentinos de pediatria Pub Date : 2025-08-28 DOI: 10.5546/aap.2025-10829.eng

M Susana Rodríguez

引用次数: 0

Cyclic Cushing syndrome and endocrine disorders in two children with Carney complex. 循环库欣综合征和内分泌紊乱2例卡尼综合征患儿。

IF 0.5 4区医学

Archivos argentinos de pediatria Pub Date : 2025-08-21 DOI: 10.5546/aap.2025-10743.eng

Ana Feller, Lincolns Mendoza, Cynthia Ferrari, María C Mattone, Mariana Aziz, Julieta Strambach, Carolina Pérez Espinosa, Paula- Flores, Laura Galluzzo Mutti, Pablo Ramírez, Mariana Costanzo

{"title":"Cyclic Cushing syndrome and endocrine disorders in two children with Carney complex.","authors":"Ana Feller, Lincolns Mendoza, Cynthia Ferrari, María C Mattone, Mariana Aziz, Julieta Strambach, Carolina Pérez Espinosa, Paula- Flores, Laura Galluzzo Mutti, Pablo Ramírez, Mariana Costanzo","doi":"10.5546/aap.2025-10743.eng","DOIUrl":"10.5546/aap.2025-10743.eng","url":null,"abstract":"Carney complex (CC) is characterized by myxomas, pigmented skin lesions, and endocrine hyperactivity, with a predisposition to tumors. Primary pigmented nodular adrenocortical disease (PPNAD) is notable, manifesting with subclinical, progressive, or cyclical symptoms of Cushing's syndrome (CS) caused by endogenous adrenocorticotropic hormone-independent hypercortisolism, and characterized by a paradoxical increase in urinary free cortisol after a corticosteroid suppression test. PPNAD should be suspected in patients with cyclic CS, and its association with CC should be considered. In cases of strong clinical suspicion, a suppression test should be performed to demonstrate the characteristic paradoxical response and ensure an early diagnosis to avoid the long-term repercussions of hypercortisolism. We describe two patients with clinical and molecular diagnosis of CC who presented with PPNAD with a characteristic biochemical pattern treated with bilateral adrenalectomy in both cases.","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510743"},"PeriodicalIF":0.5,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of an assessment protocol to operationalize the core set of the International Classification of Functioning for people with cerebral palsy. 制定评估方案，以便为脑瘫患者实施国际功能分类核心集。

IF 0.5 4区医学

Archivos argentinos de pediatria Pub Date : 2025-08-21 DOI: 10.5546/aap.2024-10550.eng

L Johana Escobar Zuluaga, María de Las M Ruiz Brunner, Eduardo Cuestas, Elisabeth Cieri, Ana L Condinanzi, Carolina Ayllon, Verónica Schiariti

引用次数: 0