Archives of Gynecology and Obstetrics最新文献

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Awareness and barriers of sacral neuromodulation in women with overactive bladder. 膀胱过度活动症妇女对骶神经调节疗法的认识和障碍。
IF 2.1 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2024-10-01 Epub Date: 2024-07-31 DOI: 10.1007/s00404-024-07664-2
Christl Reisenauer, Jürgen Andress
{"title":"Awareness and barriers of sacral neuromodulation in women with overactive bladder.","authors":"Christl Reisenauer, Jürgen Andress","doi":"10.1007/s00404-024-07664-2","DOIUrl":"10.1007/s00404-024-07664-2","url":null,"abstract":"","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":"2273-2277"},"PeriodicalIF":2.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11393171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141854560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenging biases in delivery mode decisions for women with pelvic fracture history: a call for evidence-based practices and patient-centered care. 挑战有骨盆骨折史的妇女在决定分娩方式时的偏见:呼吁循证实践和以患者为中心的护理。
IF 2.1 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2024-10-01 Epub Date: 2024-08-31 DOI: 10.1007/s00404-024-07705-w
Maya Guhan, Oluwarotimi S Nettey
{"title":"Challenging biases in delivery mode decisions for women with pelvic fracture history: a call for evidence-based practices and patient-centered care.","authors":"Maya Guhan, Oluwarotimi S Nettey","doi":"10.1007/s00404-024-07705-w","DOIUrl":"10.1007/s00404-024-07705-w","url":null,"abstract":"<p><p>Pelvic fractures significantly impact young individuals, with a prevalence of 20 per 100,000, leading to long-term complications such as chronic pain and genitourinary dysfunction. Notably, women with a history of pelvic fractures face increased cesarean section (C-sections) rates during childbirth. This editorial investigates the factors contributing to higher C-section rates in these women, including provider assumptions about delivery complications and systemic hospital biases. Despite these trends, evidence suggests that vaginal delivery can be successful, especially when considering factors like pelvic displacement and the timing of delivery post-fracture. We advocate for education programs to challenge provider biases, transparent patient communication, and evidence-based practices prioritizing patient-centered care. Addressing these issues can enhance maternal and fetal outcomes, supporting women in making informed decisions about their delivery options.</p>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":"2269-2271"},"PeriodicalIF":2.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor: Allert et al. "The influence of epidural anesthesia in pregnancies with scheduled vaginal breech delivery at term: a hospital-based retrospective analysis" in the Archives of Gynecology and Obstetrics (published online: 20th November 2023). 致编辑的信:Allert等人在《妇产科档案》(Archives of Gynecology and Obstetrics)上发表的 "硬膜外麻醉对足月阴道臀位分娩妊娠的影响:基于医院的回顾性分析"(在线发表日期:2023年11月20日)。
IF 2.1 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2024-10-01 Epub Date: 2024-04-30 DOI: 10.1007/s00404-024-07517-y
Massimiliano Lia, Holger Stepan
{"title":"Letter to the Editor: Allert et al. \"The influence of epidural anesthesia in pregnancies with scheduled vaginal breech delivery at term: a hospital-based retrospective analysis\" in the Archives of Gynecology and Obstetrics (published online: 20th November 2023).","authors":"Massimiliano Lia, Holger Stepan","doi":"10.1007/s00404-024-07517-y","DOIUrl":"10.1007/s00404-024-07517-y","url":null,"abstract":"","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":"2279-2280"},"PeriodicalIF":2.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11393192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140847371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pregnancy cholestasis typically occurs in the third trimester of pregnancy and is a significant clinical condition 妊娠胆汁淤积症通常发生在妊娠的第三个三个月,是一种重要的临床症状。
IF 2.1 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2024-10-01 DOI: 10.1007/s00404-024-07736-3
Ayça Kubat Küçükyurt, Nil Atakul, Yağmur Solak
{"title":"Pregnancy cholestasis typically occurs in the third trimester of pregnancy and is a significant clinical condition","authors":"Ayça Kubat Küçükyurt,&nbsp;Nil Atakul,&nbsp;Yağmur Solak","doi":"10.1007/s00404-024-07736-3","DOIUrl":"10.1007/s00404-024-07736-3","url":null,"abstract":"<div><h3>Aim</h3><p>The aim of this study is to determine the albumin/bilirubin ratio index and the aspartate aminotransferase (AST)/alanine aminotransferase ratio (ALT) index in patients diagnosed with cholestasis during pregnancy, and to demonstrate their correlation with liver damage. Additionally, potential strategies to prevent liver damage will be elucidated.</p><h3>Materials and method</h3><p>Our study is a retrospective study. A total of 4019 pregnant women aged between 18 and 40 years, presenting with itching complaints at 32–36 weeks of gestation, were screened at the Department of Obstetrics and Gynecology, Istanbul Training and Research Hospital of Health Sciences University between January 1, 2018, and December 31, 2023. Among them, 104 pregnant women without any other accompanying diseases were diagnosed with Gestational Cholestasis. Among the 104 diagnosed women, 78 met the inclusion criteria and were included in the study. Twenty-six women were excluded from the study due to missing albumin and total bilirubin values or due to blood samples being taken at different times. The serum albumin/bilirubin ratio index and the alanine aminotransferase/aspartate aminotransferase ratio index were calculated and statistically compared between pregnant women diagnosed with cholestasis and healthy pregnant women at the same gestational week.</p><h3>Findings</h3><p>We found that AST, ALT, albumin, and total bilirubin levels were significantly higher in pregnant women diagnosed with cholestasis compared to the control group (<i>p</i> &lt; 0.05). The AST/ALT index in the case group was significantly lower compared to the control group. However, there were no significant differences found between the case and control groups regarding the albumin/total bilirubin index and ALBI grade. When comparing ALBI grades in cases, no significant differences were found in terms of patients' age, gestational week, AST, ALT, and AST/ALT index. When compared according to ALBI grades, the albumin level was higher in patients with ALBI grade I compared to grade II, and in patients with grade II compared to grade III. The total bilirubin level was significantly higher in patients with ALBI grade III compared to grades I and II, but there was no significant difference between grades I and II. No significant differences were found among the groups separated according to ALBI grades when FBA values were compared.</p><h3>Conclusion</h3><p>In this study, the negative correlation between lower AST/ALT ratio and FBA values in patients with severe cholestasis suggests the need for careful consideration regarding future liver damage. The lack of difference in ALBI score between the case and control groups, as well as the absence of correlation with FBA values, indicates the necessity to evaluate ALBI score based on patients' long-term prognosis.</p></div>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":"310 5","pages":"2531 - 2539"},"PeriodicalIF":2.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fetal heart diseases and neonatal mortality: Risk factors and management 胎儿心脏病和新生儿死亡率:风险因素和管理。
IF 2.1 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2024-09-30 DOI: 10.1007/s00404-024-07759-w
Mucize Eric Ozdemir, Oya Demirci, Pinar Kumru, Omer Gokhan Eyisoy, Ozge Burcin Topcu Bas, Busra Cambaztepe, Karolin Ohanoglu, Ilker Kemal Yucel
{"title":"Fetal heart diseases and neonatal mortality: Risk factors and management","authors":"Mucize Eric Ozdemir,&nbsp;Oya Demirci,&nbsp;Pinar Kumru,&nbsp;Omer Gokhan Eyisoy,&nbsp;Ozge Burcin Topcu Bas,&nbsp;Busra Cambaztepe,&nbsp;Karolin Ohanoglu,&nbsp;Ilker Kemal Yucel","doi":"10.1007/s00404-024-07759-w","DOIUrl":"10.1007/s00404-024-07759-w","url":null,"abstract":"<div><h3>Purpose</h3><p>Fetal heart diseases significantly contribute to neonatal mortality. Improved prenatal diagnostics enable defect detection before delivery, emphasizing the need for a personalized approach to address anomalies and predict outcomes. Categorizing diseases into risk classes aids obstetricians in counseling and delivery decisions. This study classifies fetal heart diseases by severity, examining factors related to maternal, fetal, and delivery that affect neonatal mortality. The aim is to identify key determinants of neonatal mortality and create an individual approach to assess and manage risks in the first days of a newborn's life.</p><h3>Methods</h3><p>A prospective study from 2019 to 2023 at a tertiary care institute involved pregnant women diagnosed with fetal heart disease. 382 women were categorized into three groups based on potential risk for hemodynamic instability at birth: Group-1 (no or low risk, n = 114), Group-2 (moderate risk, n = 201), and Group-3 (high risk, n = 67). Antenatal follow-up used fetal echocardiography. The study explored the association between maternal–fetal-delivery-related factors and neonatal mortality, with statistical significance set at p &lt; 0.05.</p><h3>Results</h3><p>Significant associations with neonatal mortality were found in cases with birth weight &lt; 2500 g (p = 0.002), presence of genitourinary system anomaly (p = 0.001), group-2 and 3 heart disease (p &lt; 0.001), and induction of labor (p = 0.01).</p><h3>Conclusion</h3><p>Factors influencing neonatal mortality in fetal heart disease cases include heart disease severity (group-3 heart disease), low birth weight, and extracardiac anomalies. While labor induction with prostaglandin ± oxytocin appears to elevate neonatal mortality, this observation requires further validation with larger sample sizes. Obstetricians should consider selective use of prostaglandin for labor induction.</p></div>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":"310 5","pages":"2497 - 2505"},"PeriodicalIF":2.1,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ovarian reserve does not influence natural conception: insights from infertile women 卵巢储备并不影响自然受孕:不孕妇女的启示。
IF 2.1 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2024-09-28 DOI: 10.1007/s00404-024-07741-6
Giulia Galati, Marco Reschini, Alessandra Chine’, Laura Benaglia, Paola Vigano’, Edgardo Somigliana, Paolo Vercellini, Ludovico Muzii
{"title":"Ovarian reserve does not influence natural conception: insights from infertile women","authors":"Giulia Galati,&nbsp;Marco Reschini,&nbsp;Alessandra Chine’,&nbsp;Laura Benaglia,&nbsp;Paola Vigano’,&nbsp;Edgardo Somigliana,&nbsp;Paolo Vercellini,&nbsp;Ludovico Muzii","doi":"10.1007/s00404-024-07741-6","DOIUrl":"10.1007/s00404-024-07741-6","url":null,"abstract":"<div><h3>Purpose</h3><p>There is several albeit not univocal evidence suggesting that ovarian reserve is not related to the chance of natural pregnancy, provided that the remnant follicular pool is sufficient to ensure regular menstrual cycles. Nevertheless, available studies have some methodological limitations, and the issue cannot be considered definitively ascertained.</p><h3>Methods</h3><p>To further address this issue, we retrospectively selected infertile women whose infertility diagnostic work-up was unremarkable (unexplained infertility-cases) and matched them by age and study period to a group of infertile women who were diagnosed with severe male infertility (controls). If ovarian reserve impacts on natural fertility, one had to expect lower ovarian reserve among women with unexplained infertility. Tested biomarkers included AMH, AFC and day 2–3 serum FSH. The primary aim was the frequency of women with serum AMH &lt; 0.7 ng/ml.</p><h3>Results</h3><p>Two-hundred fifty-two women with unexplained infertility and 252 women with male infertility were included. All biomarkers of ovarian reserve did not differ between the study groups. AMH levels &lt; 0.7 ng/mL were observed in 26 (10%) women with unexplained infertility and 35 (14%) women with male infertility (<i>p</i> = 0.28). The adjusted OR was 0.76 (95% CI: 0.44–1.33). Significant differences did not also emerge when repeating this dichotomous analysis using other biomarkers and other thresholds for the definition of low-ovarian reserve.</p><h3>Conclusion</h3><p>This study confirms that ovarian reserve is unremarkable to natural conception. Physicians and patients should be aware of this concept to avoid inappropriate counseling and undue clinical decisions.</p></div>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":"310 5","pages":"2691 - 2696"},"PeriodicalIF":2.1,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00404-024-07741-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ovarian tissue cryopreservation and transplantation as a natural means to delay menopause 将卵巢组织冷冻保存和移植作为推迟绝经期的自然手段。
IF 2.1 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2024-09-28 DOI: 10.1007/s00404-024-07752-3
Koray Gorkem Sacinti, Rowaida Sadat, Sinan Ozkavukcu, Meltem Sonmezer, Murat Sonmezer
{"title":"Ovarian tissue cryopreservation and transplantation as a natural means to delay menopause","authors":"Koray Gorkem Sacinti,&nbsp;Rowaida Sadat,&nbsp;Sinan Ozkavukcu,&nbsp;Meltem Sonmezer,&nbsp;Murat Sonmezer","doi":"10.1007/s00404-024-07752-3","DOIUrl":"10.1007/s00404-024-07752-3","url":null,"abstract":"<div><p>Ovarian tissue cryopreservation and transplantation (OTCT) offers hope for preserving fertility and endocrine functions in patients undergoing gonadotoxic treatments. Advancements in techniques for the procedure have transformed OTCT from an experimental procedure into a viable option. There is a growing interest in utilizing OTCT to delay menopause and alleviate associated health issues. Menopausal transition affects women globally, leading to symptoms and long- term health risks. OTCT has the potential to restore endocrine functions, reducing menopause-related symptoms while mitigating health consequences such as osteoporosis and cardiovascular diseases. Although the use of OTCT for delaying menopause is not clinically proven, the discussion around shows potential for future utilization. In essence, the remarkable advancements in OTCT have bestowed upon us the ability to safeguard fertility and sustain the delicate endocrine functions of the ovaries. However, it is the tantalizing prospect of utilizing this technique to postpone menopause and alleviate its associated symptoms that truly captivates the imagination. Further research is imperative to substantiate the clinical efficacy of OTCT; nonetheless, its potential in menopausal therapy is both promising and warrants comprehensive exploration. This review highlights advancements and the feasibility of OTCT to postpone menopause as an alternative approach to currently used conventional menopause therapy methods.</p></div>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":"310 5","pages":"2305 - 2313"},"PeriodicalIF":2.1,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comprehensive diagnostic approach to differentiate intrauterine arteriovenous malformation in cases of enhanced myometrial vascularity 在子宫肌层血管增强的病例中鉴别宫内动静脉畸形的综合诊断方法。
IF 2.1 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2024-09-28 DOI: 10.1007/s00404-024-07754-1
Carolina Ercolino, Enrico Ferrazzi, Manuela Wally Ossola, Eugenia Di Loreto, Pierpaolo Biondetti, Serena Carriero, Ottavio Cassardo, Carolina Lanza, Francesco D’Ambrosi
{"title":"A comprehensive diagnostic approach to differentiate intrauterine arteriovenous malformation in cases of enhanced myometrial vascularity","authors":"Carolina Ercolino,&nbsp;Enrico Ferrazzi,&nbsp;Manuela Wally Ossola,&nbsp;Eugenia Di Loreto,&nbsp;Pierpaolo Biondetti,&nbsp;Serena Carriero,&nbsp;Ottavio Cassardo,&nbsp;Carolina Lanza,&nbsp;Francesco D’Ambrosi","doi":"10.1007/s00404-024-07754-1","DOIUrl":"10.1007/s00404-024-07754-1","url":null,"abstract":"<div><h3>Purpose</h3><p>The differentiation between conditions such as uterine arteriovenous malformation, pseudoaneurysm, gestational trophoblastic disease, and retained trophoblastic tissue can be challenging. Ultrasound imaging and Doppler interrogation are the primary diagnostic tools to assess cases of enhanced myometrial vascularity and differentiate intrauterine vascular anomalies. However, some cases remain of difficult differentiation. This study aims to analyze suspected cases and describe their diagnostic management and outcomes.</p><h3>Methods</h3><p>We reviewed post-abortion cases that underwent pelvic transvaginal U/S imaging and Doppler examinations due to suspected uterine vascular anomalies. CT scans were performed in cases in which ultrasound did not reach a diagnosis. Simple follow-up, medical or surgical therapy, or embolization of uterine arteries were performed according to the final diagnosis.</p><h3>Results</h3><p>From 2015 to 2022, we retrieved from electronic ultrasound records 22 cases of suspected vascular malformations. In eight cases, first-line U/S at admission excluded the suspected anomaly. In Five of the remaining 14 patients, uterine vascular anomalies were excluded upon a second-level  U/S based on angio-Doppler imaging and Doppler peak velocity interrogation. Nine cases underwent CT scan, and a digital angiography and embolization were performed in eight of these cases, of whom only two had a documented uterine arteriovenous malformation.</p><h3>Conclusion</h3><p>Our triage proved that only two out of 22 suspected cases had a uterine arteriovenous malformation. This diagnosis is frequently misused in clinical practice. Our data confirm that enhanced myometrial vascularity should be used to encompass the spectrum of possible differential diagnosis. A precise step-by-step diagnostic method is of paramount importance to prevent unnecessary interventions.</p></div>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":"310 5","pages":"2523 - 2529"},"PeriodicalIF":2.1,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of 2-year reproductive outcomes of tubal ectopic pregnancies treated with surgery, methotrexate or expectant management 采用手术、甲氨蝶呤或期待疗法治疗输卵管异位妊娠的 2 年生殖效果比较。
IF 2.1 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2024-09-27 DOI: 10.1007/s00404-024-07747-0
Fahri Burçin Fıratlıgil, Sadun Sucu, Serap Topkara Sucu, Merve Ayas Ozkan, Yildiz Akdas Reis, Murat Levent Dereli, Sadullah Ozkan, Yaprak Engin-Ustun
{"title":"Comparison of 2-year reproductive outcomes of tubal ectopic pregnancies treated with surgery, methotrexate or expectant management","authors":"Fahri Burçin Fıratlıgil,&nbsp;Sadun Sucu,&nbsp;Serap Topkara Sucu,&nbsp;Merve Ayas Ozkan,&nbsp;Yildiz Akdas Reis,&nbsp;Murat Levent Dereli,&nbsp;Sadullah Ozkan,&nbsp;Yaprak Engin-Ustun","doi":"10.1007/s00404-024-07747-0","DOIUrl":"10.1007/s00404-024-07747-0","url":null,"abstract":"<div><h3>Introduction</h3><p>To compare the 2-year reproductive outcomes of tubal ectopic pregnancies (EP) treated with surgery, methotrexate (MTX) or expectant management.</p><h3>Materials and methods</h3><p>This case–control study was conducted retrospectively at the Obstetrics-Gynecology and Perinatology Clinics of Etlik Zubeyde Hanim Women’s Health Education and Training Hospital. 985 of 1156 patients, who were managed between January 2015 and December 2019 for a tubal EP, tried to conceive in 2 years after treatment: 366 patients underwent surgical treatment; 549 patients were treated with MTX, and 70 patients had expectant management. Clinical data and fertility outcomes were retrieved by medical and hospital records. We compared the three groups based on the 2-year reproductive outcomes of three treatment modalities of tubal EP.</p><h3>Results</h3><p>There was a significant difference in the frequency of no pregnancy in patients who underwent surgery compared to patients who received expectant management and MTX therapy (<i>p</i> &lt; 0.001). The frequency of no pregnancy was higher in patients who underwent surgery. There was no significant difference between expectant management and MTX therapy (<i>p</i> = 0.411). In the reproductive outcomes of patients who underwent surgery, the incidence of viable pregnancies was statistically lower than in the group treated with expectant management and MTX therapy (<i>p</i> = 0.003).</p><h3>Conclusions</h3><p>Patients with an EP often have a future desire to have children, the treatment options are also important. The earlier the diagnosis is made, the more likely it is that expectant management or MTX treatment will be considered. With these two treatment methods, the likelihood of having a child in the future is higher than with surgical treatment.</p></div>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":"310 5","pages":"2561 - 2568"},"PeriodicalIF":2.1,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of outcomes and risk factors for recurrent preeclampsia in a subsequent pregnancy 评估再次怀孕时子痫前期复发的结果和风险因素。
IF 2.1 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2024-09-27 DOI: 10.1007/s00404-024-07751-4
Qingwen Nie, Boxin Zhou, Yafei Wang, Minqing Ye, Dunjin Chen, Fang He
{"title":"Evaluation of outcomes and risk factors for recurrent preeclampsia in a subsequent pregnancy","authors":"Qingwen Nie,&nbsp;Boxin Zhou,&nbsp;Yafei Wang,&nbsp;Minqing Ye,&nbsp;Dunjin Chen,&nbsp;Fang He","doi":"10.1007/s00404-024-07751-4","DOIUrl":"10.1007/s00404-024-07751-4","url":null,"abstract":"<div><h3>Purpose</h3><p>The aim was to evaluate the pregnancy outcomes and identify risk factors for recurrent preeclampsia (PE).</p><h3>Methods</h3><p>Retrospective analysis of patients discharged with PE between January 1, 2010, and January 1, 2023, from two tertiary referral hospitals. They were classified into recurrent and non-recurrent groups based on the presence of PE in subsequent pregnancies.</p><h3>Results</h3><p>Among 519 women who had a subsequent pregnancy after a history of PE, 153 developed recurrent PE while 366 did not. The recurrent cases included 81 preterm PE, of which 41 were early-onset PE (EOPE). Recurrent PE correlated significantly with prior EOPE, HELLP syndrome, placental abruption, and stillbirth, as well as with current chronic hypertension (CH) and type 2 diabetes. The recurrent group showed a 5.8-fold higher risk of preterm birth (PTB) compared to the non-recurrent group (50.7% vs. 8.7%). Notably, 58.1% of the PTBs in the non-recurrent group were spontaneous. Logistic regression identified previous EOPE (aOR: 4.22 [95% CI: 2.50–7.13]) and current CH (aOR: 1.86 [95% CI: 1.09–3.18]) as independent contributors for recurrent PE. Furthermore, recurrent preterm PE shared the same risk factors: previous EOPE (aOR: 5.27 [95% CI: 2.82–9.85]) and current CH (aOR: 2.99 [95% CI: 1.57–5.71]). The morbidity of CH in subsequent pregnancy peaked at 31.9% when women with a history of EOPE delivered within three years.</p><h3>Conclusion</h3><p>Previous EOPE and current CH were sequentially crucial risk factors for the development of PE and preterm PE during the next pregnancy. This may clarify risk stratification in prenatal management for women with a history of PE.</p></div>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":"310 5","pages":"2487 - 2495"},"PeriodicalIF":2.1,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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