Archives of Medical Research最新文献

筛选
英文 中文
COVID-19 policy response: Perspectives of key stakeholders in Mexico's health system and implications for resilience COVID-19 政策回应:墨西哥卫生系统主要利益攸关方的观点及其对复原力的影响
IF 4.7 3区 医学
Archives of Medical Research Pub Date : 2024-10-15 DOI: 10.1016/j.arcmed.2024.103097
Lina Díaz-Castro , Christian Díaz de León-Castañeda , Galileo Pérez-Hernández , José Carlos Suárez-Herrera
{"title":"COVID-19 policy response: Perspectives of key stakeholders in Mexico's health system and implications for resilience","authors":"Lina Díaz-Castro ,&nbsp;Christian Díaz de León-Castañeda ,&nbsp;Galileo Pérez-Hernández ,&nbsp;José Carlos Suárez-Herrera","doi":"10.1016/j.arcmed.2024.103097","DOIUrl":"10.1016/j.arcmed.2024.103097","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aims to analyze the perspectives of key stakeholders within Mexico's health system regarding the policy response to COVID-19 in 2020 to inform future policy formulation.</div></div><div><h3>Methods</h3><div>This qualitative study is based on a secondary data analysis (SDA) derived from a broader primary research on governance in Mexico during the COVID-19 pandemic. The analysis adopted a grounded theory approach to examine 15 semi-structured interviews with prominent figures in the health system between June and November 2020. The interviews were audio-recorded and analyzed through the lens of the Health Policy Triangle which includes context, key actors, and the Mexican health policy process. Moreover, the analysis was enriched by incorporating the framework outlined in the World Health Organization's COVID-19 Strategic Preparedness and Response Plan (SPRP).</div></div><div><h3>Results</h3><div>The findings indicate that key stakeholders perceived a centralized approach to policymaking with a strong emphasis on cross-sector communication, expert panels, equity-focused measures, accessibility to healthcare services (promoting portability), and improvements in the health information system.</div></div><div><h3>Conclusion</h3><div>Key stakeholders recognized the response to COVID-19 was complex, involving multiple dimensions and levels of action. The importance of preparedness and response in building health system resilience is emphasized. Recommendations include explicitly integrating resilience into national and local policy agendas, addressing systemic structural deficiencies, promoting equity in the pandemic response, improving risk governance, strengthening coordination mechanisms, ensuring supply chain resilience, improving personnel training, and enhancing local diagnostic capacity to better prepare for future public health emergencies.</div></div>","PeriodicalId":8318,"journal":{"name":"Archives of Medical Research","volume":"56 2","pages":"Article 103097"},"PeriodicalIF":4.7,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142432021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post COVID-19: Advancing medical laboratory service integration in nigeria and progress towards establishing integration guideline 后 COVID-19:推进尼日利亚医学实验室服务一体化以及在制定一体化准则方面取得的进展
IF 4.7 3区 医学
Archives of Medical Research Pub Date : 2024-10-14 DOI: 10.1016/j.arcmed.2024.103094
Augustine Onyeaghala , Nkechi Nwoke , Kingsley Odiabara , Ughweroghene Kingston Omo-Emmanuel , Jibrin Kama , Bashir Mahmud , Charles Michael Etoroma , Gaius Mathew
{"title":"Post COVID-19: Advancing medical laboratory service integration in nigeria and progress towards establishing integration guideline","authors":"Augustine Onyeaghala ,&nbsp;Nkechi Nwoke ,&nbsp;Kingsley Odiabara ,&nbsp;Ughweroghene Kingston Omo-Emmanuel ,&nbsp;Jibrin Kama ,&nbsp;Bashir Mahmud ,&nbsp;Charles Michael Etoroma ,&nbsp;Gaius Mathew","doi":"10.1016/j.arcmed.2024.103094","DOIUrl":"10.1016/j.arcmed.2024.103094","url":null,"abstract":"<div><h3>Background</h3><div>The Nigerian healthcare system, including medical laboratories, operates in a three-tiered structure across public and private sectors. Lessons from COVID-19 show the urgent need for a guideline to drive medical laboratory service integration.</div></div><div><h3>Problem</h3><div>Lack of operational guideline to drive the integration of laboratory services has resulted in siloed operations across different medical laboratories causing duplication of resources, coordination issues, and inefficiencies.</div></div><div><h3>Aim</h3><div>To highlight the development processes of medical laboratory service integration guideline and discuss its key provisions.</div></div><div><h3>Method</h3><div>The Medical Laboratory Services Division (MLSD), Federal Ministry of Health (FMoH) initiated the development of a national guideline for integrating medical laboratory services. Partnering with stakeholders and engaging two consultants, a technical workshop was facilitated in January 2024. The Consultants garnered the initial inputs stakeholders made at the five-day meeting. The inputs were collated and organized to produce the guideline. The guideline was circulated to participants and other stakeholders for review and feedback received was used to finalize the document. The MLSD with support from partners further held a three-day stakeholders’ meeting in May 2024 to validate the document before submitting it to the Health Minister for endorsement.</div></div><div><h3>Result</h3><div>The guideline sets standards for achieving medical laboratory services and systems integration across different medical laboratories. The contents of the guideline are enumerated and respective recommendations made under each element are highlighted.</div></div><div><h3>Conclusion</h3><div>The implementation of the guideline will help harmonize services, improve access to diagnostics, streamline processes, reduce redundancies, optimize resource utilization, enhance communication, data sharing, and pandemic preparedness.</div></div>","PeriodicalId":8318,"journal":{"name":"Archives of Medical Research","volume":"56 1","pages":"Article 103094"},"PeriodicalIF":4.7,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Masseter Muscle Volume and Its Association with Sarcopenia and Muscle Determinants in Older Japanese Adults: the Bunkyo Health Study 日本老年人的肌肉量及其与肌肉疏松症和肌肉决定因素的关系:文化健康研究
IF 4.7 3区 医学
Archives of Medical Research Pub Date : 2024-10-14 DOI: 10.1016/j.arcmed.2024.103095
Abulaiti Abudurezake , Saori Kakehi , Futaba Umemura , Hideyoshi Kaga , Yuki Someya , Hiroki Tabata , Yasuyo Yoshizawa , Hitoshi Naito , Tsubasa Tajima , Naoaki Ito , Hikaru Otsuka , Huicong Shi , Mari Sugimoto , Shota Sakamoto , Yukiko Muroga , Hidetaka Wakabayashi , Ryuzo Kawamori , Hirotaka Watada , Yoshifumi Tamura
{"title":"Masseter Muscle Volume and Its Association with Sarcopenia and Muscle Determinants in Older Japanese Adults: the Bunkyo Health Study","authors":"Abulaiti Abudurezake ,&nbsp;Saori Kakehi ,&nbsp;Futaba Umemura ,&nbsp;Hideyoshi Kaga ,&nbsp;Yuki Someya ,&nbsp;Hiroki Tabata ,&nbsp;Yasuyo Yoshizawa ,&nbsp;Hitoshi Naito ,&nbsp;Tsubasa Tajima ,&nbsp;Naoaki Ito ,&nbsp;Hikaru Otsuka ,&nbsp;Huicong Shi ,&nbsp;Mari Sugimoto ,&nbsp;Shota Sakamoto ,&nbsp;Yukiko Muroga ,&nbsp;Hidetaka Wakabayashi ,&nbsp;Ryuzo Kawamori ,&nbsp;Hirotaka Watada ,&nbsp;Yoshifumi Tamura","doi":"10.1016/j.arcmed.2024.103095","DOIUrl":"10.1016/j.arcmed.2024.103095","url":null,"abstract":"<div><h3>Aim</h3><div>Sarcopenia has been with a decrease in masseter muscle (MM) thickness in high-risk older populations. However, the relationship between sarcopenia and determinants of MM volume (MMV) in the general elderly population remains unclear.</div></div><div><h3>Method</h3><div>In a cross-sectional study of 1,484 older adults in Tokyo, we evaluated MMV using 3D MRI scanning, appendicular skeletal muscle mass (ASMM), handgrip strength, dietary intake, smoking, insulin-like growth factor 1 (IGF-1) levels, and the ACTN3 R577X polymorphism. Participants were divided into quintiles based on MMV (<em>Q1</em>–5).</div></div><div><h3>Results</h3><div>Participants in our study had a mean age of 73.0 ± 5.3 years and their MMV (Men: 35.3 ± 7.8 mL, Women: 25.0 ± 5.1 mL) was significantly higher in men than in women. A significant association between MMV and sarcopenia was observed, with the lowest quintile (<em>Q1</em>) showing a higher risk compared to the highest quintile (<em>Q5</em>) in both sexes. Body mass index (BMI) and age were independent determinants of ASMM in both sexes, whereas BMI, but interestingly not age, was a determinant of MMV. Moreover, IGF-1 was positively correlated with MMV in both sexes; smoking was negatively correlated with MMV in women. The ACTN3 577XX genotype was only associated with smaller MMV in men.</div></div><div><h3>Conclusion</h3><div>Low MMV increased the risk of sarcopenia, particularly in men. BMI and age strongly influenced ASMM, while MMV was only weakly associated with BMI and not with age. Notably, IGF-1 level was positively associated with MMV only, and ACTN3 genotype was associated to reduced MMV only in men.</div></div>","PeriodicalId":8318,"journal":{"name":"Archives of Medical Research","volume":"56 1","pages":"Article 103095"},"PeriodicalIF":4.7,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142432866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kidney growth progression patterns in autosomal dominant polycystic kidney disease 常染色体显性多囊肾的肾脏发育模式
IF 4.7 3区 医学
Archives of Medical Research Pub Date : 2024-10-10 DOI: 10.1016/j.arcmed.2024.103099
Aaron Pérez-Segovia , Gabriel Cojuc-Konigsberg , Estefania Reul-Linares , Elisa Naomi Hernández-Paredes , Mónica Chapa-Ibargüengoitia , Juan C. Ramírez-Sandoval
{"title":"Kidney growth progression patterns in autosomal dominant polycystic kidney disease","authors":"Aaron Pérez-Segovia ,&nbsp;Gabriel Cojuc-Konigsberg ,&nbsp;Estefania Reul-Linares ,&nbsp;Elisa Naomi Hernández-Paredes ,&nbsp;Mónica Chapa-Ibargüengoitia ,&nbsp;Juan C. Ramírez-Sandoval","doi":"10.1016/j.arcmed.2024.103099","DOIUrl":"10.1016/j.arcmed.2024.103099","url":null,"abstract":"<div><h3>Background</h3><div>Prognosis for autosomal dominant polycystic kidney disease (ADPKD), the main inherited cause of kidney failure, relies on estimating cystic growth using linear formulas derived from height-adjusted total kidney volume (Ht-TKV). However, nonlinear renal growth patterns may occur in typical ADPKD.</div></div><div><h3>Aims</h3><div>To determine kidney outcomes of subjects diagnosed with typical ADPKD exhibiting nonlinear, and unpredictable cystic growth during follow-up.</div></div><div><h3>Methods</h3><div>Retrospective cohort study. We categorized TKV changes in individuals with typical ADPKD according to observed kidney growth trajectories. Ht-TKV was calculated from consecutive CT or MRI using the ellipsoid method. We compared estimated glomerular filtration rate (eGFR) trajectories with linear mixed models.</div></div><div><h3>Results</h3><div>We included 83 individuals with ADPKD (67% women; age 47 ± 12 years; follow-up 5.2 years [IQR 2.8–9.0]). Three kidney growth patterns were observed: slow progression (24%, &lt;3%/year linear increase), fast progression (39%, ≥3%/year linear increase), and atypical progression (37%, nonlinear growth). Adjusted ht-TKV change in mL/m/year was +1.4 (IQR –4.5 to +10.0), +40.3 (+16.9 to +89.3), and +32.8 (+15.9 to +85.9) for slow, fast, and atypical progressors, respectively (<em>p</em> &lt; 0.001). Atypical progressors exhibited a significantly greater decline in eGFR in mL/min/m²/year (–7.9, 95% CI –6.5, –3.9) compared to slow (–0.5, 95% CI –3.1 to +0.5) and fast progressors (–3.4, 95% CI –7.9, –2.0; between-group <em>p</em> &lt; 0.001). Atypical progressors had a higher proportion of acute complications, including hemorrhages, infections, and urolithiasis (84%), compared to slow (20%) and fast progressors (31%) (<em>p</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>In typical ADPKD, nonlinear, abrupt, and unpredictable cyst growth occurs frequently, leading to a higher risk of acute complications and kidney function decline.</div></div>","PeriodicalId":8318,"journal":{"name":"Archives of Medical Research","volume":"56 2","pages":"Article 103099"},"PeriodicalIF":4.7,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Theranostics advances in the treatment and diagnosis of neurological and neurosurgical diseases Theranostics 推进了神经和神经外科疾病的治疗和诊断。
IF 4.7 3区 医学
Archives of Medical Research Pub Date : 2024-10-05 DOI: 10.1016/j.arcmed.2024.103085
Wireko Andrew Awuah , Arjun Ahluwalia , Joecelyn Kirani Tan , Vivek Sanker , Sakshi Roy , Adam Ben-Jaafar , Devansh Mitesh Shah , Pearl Ohenewaa Tenkorang , Nicholas Aderinto , Toufik Abdul-Rahman , Oday Atallah , Athanasios Alexiou
{"title":"Theranostics advances in the treatment and diagnosis of neurological and neurosurgical diseases","authors":"Wireko Andrew Awuah ,&nbsp;Arjun Ahluwalia ,&nbsp;Joecelyn Kirani Tan ,&nbsp;Vivek Sanker ,&nbsp;Sakshi Roy ,&nbsp;Adam Ben-Jaafar ,&nbsp;Devansh Mitesh Shah ,&nbsp;Pearl Ohenewaa Tenkorang ,&nbsp;Nicholas Aderinto ,&nbsp;Toufik Abdul-Rahman ,&nbsp;Oday Atallah ,&nbsp;Athanasios Alexiou","doi":"10.1016/j.arcmed.2024.103085","DOIUrl":"10.1016/j.arcmed.2024.103085","url":null,"abstract":"<div><div>Theranostics represents a significant advance in the fields of neurology and neurosurgery, offering innovative approaches that combine the diagnosis and treatment of various neurological disorders. This innovation serves as a cornerstone of personalized medicine, where therapeutic strategies are closely integrated with diagnostic tools to enable precise and targeted interventions. Primary research results emphasize the profound impact of theranostics in Neuro Oncol. In this context, it has provided valuable insights into the complexity of the tumor microenvironment and mechanisms of resistance. In addition, in the field of neurodegenerative diseases (NDs), theranostics has facilitated the identification of distinct disease subtypes and novel therapeutic targets. It has also unravelled the intricate pathophysiology underlying conditions such as cerebrovascular disease (CVD) and epilepsy, setting the stage for more refined treatment approaches. As theranostics continues to evolve through ongoing research and refinement, its goals include further advancing the field of precision medicine, developing practical biomarkers for clinical use, and opening doors to new therapeutic opportunities. Nevertheless, the integration of these approaches into clinical settings presents challenges, including ethical considerations, the need for advanced data interpretation, standardization of procedures, and ensuring cost-effectiveness. Despite these obstacles, the promise of theranostics to significantly improve patient outcomes in the fields of neurology and neurosurgery remains a source of optimism for the future of healthcare.</div></div>","PeriodicalId":8318,"journal":{"name":"Archives of Medical Research","volume":"56 1","pages":"Article 103085"},"PeriodicalIF":4.7,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Follicle-stimulating hormone sweetness: How carbohydrate structures impact on the biological function of the hormone 促卵泡激素的甜味:碳水化合物结构如何影响激素的生物功能。
IF 4.7 3区 医学
Archives of Medical Research Pub Date : 2024-10-05 DOI: 10.1016/j.arcmed.2024.103091
Alfredo Ulloa-Aguirre , Regina Llamosas , James A. Dias
{"title":"Follicle-stimulating hormone sweetness: How carbohydrate structures impact on the biological function of the hormone","authors":"Alfredo Ulloa-Aguirre ,&nbsp;Regina Llamosas ,&nbsp;James A. Dias","doi":"10.1016/j.arcmed.2024.103091","DOIUrl":"10.1016/j.arcmed.2024.103091","url":null,"abstract":"<div><div>Follicle-stimulating hormone (FSH), or follitropin, exists in multiple molecular forms due largely to its protein-carbohydrate composition and the complexity of the glycans attached to the protein core. The heterogeneity of gonadotropins exists in two forms, macroheterogeneity, which results from the absence of one or two oligosaccharide chains in the ß-subunit, and microheterogeneity which results from variation in the structures and complexity of the glycans attached to the hormone. In the clinical arena, FSH compounds are widely used by fertility specialists to promote ovarian follicle growth and maturation to a preovulatory follicle containing a fertilization-competent oocyte. Several genetically engineered recombinant human FSH preparations have been added to the arsenal of follitropin preparations in several countries for the treatment of infertility, particularly in women attending assisted reproduction clinics. Although the primary structure of these recombinant proteins is identical to that of naturally occurring FSH, the cell context and variations in the production and purification processes may impact the glycosidic profile of the recombinant FSH macro- and micro-heterogeneity, which may potentially influence the pharmacokinetics and pharmacodynamics of the compound. This review concentrates on the structure-function correlates of follitropin, with emphasis on the physiological and biological importance of the carbohydrates attached to its protein core, including its pharmacokinetics and biological activity. Emphasis is placed on pituitary FSH, and the available data on the various recombinant FSH preparations employed in therapeutics are also discussed, considering that this gonadotropin represents the cornerstone for the treatment of infertility in modern assisted reproduction.</div></div>","PeriodicalId":8318,"journal":{"name":"Archives of Medical Research","volume":"55 8","pages":"Article 103091"},"PeriodicalIF":4.7,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on “Serendipitous adrenal hyperplasia in patients admitted to the emergency department for suspected SARS-CoV-2 infection is linked to increased mortality” 就 "急诊科收治的疑似 SARS-CoV-2 感染者偶然出现的肾上腺增生与死亡率升高有关 "发表评论
IF 4.7 3区 医学
Archives of Medical Research Pub Date : 2024-10-05 DOI: 10.1016/j.arcmed.2024.103088
Hinpetch Daungsupawong , Viroj Wiwanitkit
{"title":"Comment on “Serendipitous adrenal hyperplasia in patients admitted to the emergency department for suspected SARS-CoV-2 infection is linked to increased mortality”","authors":"Hinpetch Daungsupawong ,&nbsp;Viroj Wiwanitkit","doi":"10.1016/j.arcmed.2024.103088","DOIUrl":"10.1016/j.arcmed.2024.103088","url":null,"abstract":"","PeriodicalId":8318,"journal":{"name":"Archives of Medical Research","volume":"56 1","pages":"Article 103088"},"PeriodicalIF":4.7,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design and implementation of a stakeholder consultation process for rapid health technology assessments in Argentina 阿根廷快速卫生技术评估利益相关者磋商程序的设计与实施。
IF 4.7 3区 医学
Archives of Medical Research Pub Date : 2024-10-05 DOI: 10.1016/j.arcmed.2024.103093
Andrea Alcaraz, Emiliano Navarro, Verónica Alfie, Lucas Perelli, Sebastián García Martí, Agustín Ciapponi, Ariel Bardach, Andrés Pichon-Riviere, Federico Augustovski
{"title":"Design and implementation of a stakeholder consultation process for rapid health technology assessments in Argentina","authors":"Andrea Alcaraz,&nbsp;Emiliano Navarro,&nbsp;Verónica Alfie,&nbsp;Lucas Perelli,&nbsp;Sebastián García Martí,&nbsp;Agustín Ciapponi,&nbsp;Ariel Bardach,&nbsp;Andrés Pichon-Riviere,&nbsp;Federico Augustovski","doi":"10.1016/j.arcmed.2024.103093","DOIUrl":"10.1016/j.arcmed.2024.103093","url":null,"abstract":"<div><h3>Introduction</h3><div>Health technology assessment (HTA) is a standardized methodology that allows the assessment technologies’ value. By incorporating the perspective of stakeholders in a public consultation process, transparency and quality of decisions can be improved.</div></div><div><h3>Objective</h3><div>To describe the active stakeholder consultation process for rapid HTAs in an Argentinean, independent, academic, non-profit HTA agency, assessing its initial five years.</div></div><div><h3>Methods</h3><div>Since 2017, we have been conducting an active public consultation process for rapid HTA documents, inviting producers, healthcare professionals, and patient organizations to provide comments, and their input may lead to changes in the HTA documents. Changes were classified as major (changes to the coverage recommendation), intermediate (changes in efficacy, net benefit, or cost-effectiveness that did not change coverage recommendations), and minor modifications (other changes).</div></div><div><h3>Results</h3><div>From May 2017–August 2022, 308 rapid HTA (rHTA) reports were published, and 3,438 invitations were sent. 140 rHTA (45.5%) received a total of 228 comments. Comments came from producers in 53% (<em>n</em> = 112) and healthcare professional organizations in 31.2% (<em>n</em> = 66). Technologies evaluated were drugs in 37% (<em>n</em> = 114), procedures in 35.5% (<em>n</em> = 109), diagnostic methods in 15.3% (<em>n</em> = 47), and devices in 12.2% (<em>n</em> = 38). Out of 308 rHTA documents, 120 (39%) were modified—mostly minor adjustments (<em>n</em> = 100; 80%), followed by major (<em>n</em> = 12; 10%) and intermediate modifications (<em>n</em> = 8; 6.4%).</div></div><div><h3>Conclusion</h3><div>Implementing an active stakeholder involvement process in HTA is feasible in a low- to middle-income country context and strengthens and improves the HTA process.</div></div>","PeriodicalId":8318,"journal":{"name":"Archives of Medical Research","volume":"56 1","pages":"Article 103093"},"PeriodicalIF":4.7,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bypassing sources of care by level and coverage: Access to essential services in Peru and Uruguay in the post-pandemic era 按级别和覆盖范围划分的绕过医疗来源:后流行病时代秘鲁和乌拉圭的基本服务获取情况。
IF 4.7 3区 医学
Archives of Medical Research Pub Date : 2024-10-05 DOI: 10.1016/j.arcmed.2024.103087
Jesús Medina-Ranilla , Hannah H. Leslie , Javier Roberti , Laura Espinoza-Pajuelo , Marina Guglielmino , Agustina Mazzoni , Ezequiel García-Elorrio , Patricia J. García
{"title":"Bypassing sources of care by level and coverage: Access to essential services in Peru and Uruguay in the post-pandemic era","authors":"Jesús Medina-Ranilla ,&nbsp;Hannah H. Leslie ,&nbsp;Javier Roberti ,&nbsp;Laura Espinoza-Pajuelo ,&nbsp;Marina Guglielmino ,&nbsp;Agustina Mazzoni ,&nbsp;Ezequiel García-Elorrio ,&nbsp;Patricia J. García","doi":"10.1016/j.arcmed.2024.103087","DOIUrl":"10.1016/j.arcmed.2024.103087","url":null,"abstract":"<div><h3>Background and aims</h3><div>Healthcare provision to distinct social groups in Latin America contributes to inequities. Individuals make active choices by bypassing their coverage and intended healthcare source. After the pandemic, we sought to characterize bypassing behaviors and quantify their effects on access to essential services.</div></div><div><h3>Methods</h3><div>Cross-sectional data from a population-based telephone survey in Peru and Uruguay were analyzed. Participants were selected by random digit dialing. Outcomes were defined as access to preventive screenings and satisfaction of emerging health needs. Bypassing by level was defined as when participants went around primary care for the usual source of care or last preventive visit; bypassing by coverage when care was sought outside of public coverage or social security. Sociodemographic characteristics were included, and the adjusted average treatment effect was calculated.</div></div><div><h3>Results</h3><div>Data from 1,255 participants in Peru and 1,237 participants in Uruguay were analyzed. Bypassing behaviors by level (32% Peru; 60% Uruguay) and coverage (29% Peru; 21% Uruguay) were more prevalent in more privileged groups, especially in Peru. System competence was low overall and varied by bypassing mode, especially in Peru. In the adjusted analysis, statistically significant differences were found in bypassing by coverage in Peru (–8% difference in unmet health needs) and by level in Uruguay (5% more unmet needs).</div></div><div><h3>Conclusion</h3><div>Provision of essential preventive services was insufficient in both countries. In Peru, bypassing could serve as a proxy measure of inequities. Reminders of preventive services could be offered to bypassers of primary care. Profound health system reforms are needed to ensure equitable access to essential services.</div></div>","PeriodicalId":8318,"journal":{"name":"Archives of Medical Research","volume":"56 1","pages":"Article 103087"},"PeriodicalIF":4.7,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetics in reproductive medicine 生殖医学遗传学。
IF 4.7 3区 医学
Archives of Medical Research Pub Date : 2024-09-28 DOI: 10.1016/j.arcmed.2024.103092
Isabel Ochando , Antonio Urbano , Joaquín Rueda
{"title":"Genetics in reproductive medicine","authors":"Isabel Ochando ,&nbsp;Antonio Urbano ,&nbsp;Joaquín Rueda","doi":"10.1016/j.arcmed.2024.103092","DOIUrl":"10.1016/j.arcmed.2024.103092","url":null,"abstract":"<div><div>Thanks to advances in technology, genetic testing is now available to explore the causes of infertility and to assess the risk of a given couple passing on a genetic disorder to their offspring. This allows at-risk couples to make an informed decision when opting for assisted reproduction and allows professionals to offer pre-implantation diagnosis when appropriate. Genetic screening of an infertile couple has thus become standard practice for an appropriate diagnosis, treatment, and prognostic assessment. This review aims to highlight the conditions under which genetic screening plays a role in improving reproductive outcomes for infertile couples.</div></div>","PeriodicalId":8318,"journal":{"name":"Archives of Medical Research","volume":"55 8","pages":"Article 103092"},"PeriodicalIF":4.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信