Annals of Nutrition and Metabolism最新文献

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The 33rd Annual Congress of ECOG, Ghent, Belgium, October 8-10, 2024, Abstracts. 第 33 届 ECOG 年会,比利时根特,2024 年 10 月 8-10 日,摘要。
IF 3.2 3区 医学
Annals of Nutrition and Metabolism Pub Date : 2024-01-01 Epub Date: 2024-10-07 DOI: 10.1159/000540849
{"title":"The 33rd Annual Congress of ECOG, Ghent, Belgium, October 8-10, 2024, Abstracts.","authors":"","doi":"10.1159/000540849","DOIUrl":"10.1159/000540849","url":null,"abstract":"","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":" ","pages":"337-353"},"PeriodicalIF":3.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Protein Intake after Intensive Care Unit on Discharge Destination for Critically Ill Patients: A Single-Center Prospective Observational Study. 重症监护室后蛋白质摄入对重症患者出院去向的影响:单中心前瞻性观察研究。
IF 3.2 3区 医学
Annals of Nutrition and Metabolism Pub Date : 2024-01-01 Epub Date: 2024-07-18 DOI: 10.1159/000540301
Yoshifumi Katsumata, Tomoaki Yatabe, Hajime Kuroiwa, Hideki Iwata, Shota Oda, Takashi Kawano
{"title":"Impact of Protein Intake after Intensive Care Unit on Discharge Destination for Critically Ill Patients: A Single-Center Prospective Observational Study.","authors":"Yoshifumi Katsumata, Tomoaki Yatabe, Hajime Kuroiwa, Hideki Iwata, Shota Oda, Takashi Kawano","doi":"10.1159/000540301","DOIUrl":"10.1159/000540301","url":null,"abstract":"<p><strong>Introduction: </strong>Although nutritional therapy may be able to enable intensive care unit (ICU) survivors to return home instead of being discharged to a rehabilitation facility, post-ICU discharge nutritional therapy lacks investigation. This study evaluated the impact of nutritional therapy after ICU on discharge destination in critically ill patients.</p><p><strong>Methods: </strong>We enrolled consecutive adult patients who spent &gt;72 h in the ICU from December 2020 to March 2023. The primary outcome was discharge destination. Energy and protein intake during the ICU stay and on days 7 and 14 after ICU discharge were evaluated. The target protein intake during the intensive treatment and general ward phases were 0.8 and 1.0 g/kg/day, respectively. Patients were categorized into home discharge (group A) and rehabilitation transfer (group B) groups. Factors affecting the discharge destination were evaluated using logistic regression analysis.</p><p><strong>Results: </strong>Of the 183 patients included, 134 belonged to group A and 49 to group B. In group A, more patients reached the protein intake target than in group B. Logistic regression analysis identified achieving the protein intake target as an independent predictor of home discharge.</p><p><strong>Conclusion: </strong>Further studies are required to confirm the relationship between nutritional therapy during general ward and patient outcomes.</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":" ","pages":"287-294"},"PeriodicalIF":3.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141615834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Update on the Diagnosis and Management of Faltering Growth and Catch-Up Growth in Young Children. 幼儿生长迟缓和追赶性生长的诊断和管理最新情况。
IF 3.2 3区 医学
Annals of Nutrition and Metabolism Pub Date : 2024-01-01 Epub Date: 2024-11-12 DOI: 10.1159/000540930
Rosan Meyer
{"title":"An Update on the Diagnosis and Management of Faltering Growth and Catch-Up Growth in Young Children.","authors":"Rosan Meyer","doi":"10.1159/000540930","DOIUrl":"10.1159/000540930","url":null,"abstract":"<p><strong>Background: </strong>The term \"faltering growth\" (FG) is widely used to refer to a slower rate of weight gain in childhood than expected for age and gender. The prevalence varies depending on the definition and the studied population. Early recognition is important when considering the short- and long-term consequences, which include reduced cognitive development and increased risk of morbidity and mortality.</p><p><strong>Summary: </strong>The causes of FG are traditionally classified into being either illness- or non-illness-related. However, such a rigid classification does not acknowledge the fact that poor growth may be multifactorial. While many definitions for FG exist, a recent consensus document suggested that a drop of weight-for-height of 1 z-score warrants the consideration for FG. The nutritional assessment supports the calculation of energy and protein requirements, which should be tailored to the underlying cause.</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":" ","pages":"18-28"},"PeriodicalIF":3.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What Is Normal Growth? Principles, Practicalities and Pitfalls of Growth Assessments in Infants and Children. 什么是正常生长?婴儿和儿童生长评估的原则、实用性和误区》。
IF 3.2 3区 医学
Annals of Nutrition and Metabolism Pub Date : 2024-01-01 Epub Date: 2024-11-27 DOI: 10.1159/000541226
Tanis R Fenton, Nicole Gilbert, Seham Elmrayed, Carol J Fenton, Dana L Boctor
{"title":"What Is Normal Growth? Principles, Practicalities and Pitfalls of Growth Assessments in Infants and Children.","authors":"Tanis R Fenton, Nicole Gilbert, Seham Elmrayed, Carol J Fenton, Dana L Boctor","doi":"10.1159/000541226","DOIUrl":"10.1159/000541226","url":null,"abstract":"<p><strong>Background: </strong>Growth assessments are a pillar of public health surveillance, individual health screening, and clinical care. Normal growth is defined differently for individuals versus populations. The World Health Organization (WHO) growth standards were developed to describe the pattern of growth in healthy children without socioeconomic limitations whose mothers planned to breastfeed. The growth standards' cut-off points of ±2 standard deviations (z-scores) were defined for population assessments, based on attained size, to describe stunting and wasting at the lower end and overweight at the higher end. In a healthy population, one would expect 2.3% of the population to be above and below these cut-points. Higher child mortality rates associated with higher rates of stunting and wasting noted in observational studies validated these WHO cut-offs. There are knowledge gaps influencing the accuracy and effectiveness of growth assessments in individual children, posing challenges for health care providers.</p><p><strong>Summary: </strong>The principles of assessing normal growth in children and preterm infants are reviewed, along with pitfalls to be avoided. Growth is determined by genetics and modified by the interplay with nutritional, environmental, socioeconomic, and possibly intergenerational factors. This complexity is reflected at both the population and individual level. However, normal growth in an individual has unique-specific factors so requires a comprehensive assessment. Normal growth for an individual child could be defined as the progression of changes in anthropometric measurements to achieve the individual's genetic potential. A misdiagnosis of growth faltering can occur if infants and children are assessed with one-time rather than serial measures, and if age is not corrected for prematurity. Health care provider sensitivity and cognizance when communicating about a child's size is important for parental reassurance and avoiding stigma and unnecessary pressures or restrictions around feeding.</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":" ","pages":"7-17"},"PeriodicalIF":3.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142738300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Shifting Sands of Infant Feeding Policy. 婴儿喂养政策的风云变幻。
IF 3.2 3区 医学
Annals of Nutrition and Metabolism Pub Date : 2024-01-01 Epub Date: 2024-10-04 DOI: 10.1159/000541712
Stewart Forsyth
{"title":"The Shifting Sands of Infant Feeding Policy.","authors":"Stewart Forsyth","doi":"10.1159/000541712","DOIUrl":"10.1159/000541712","url":null,"abstract":"","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":" ","pages":"334-336"},"PeriodicalIF":3.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11614412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142379977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beneficial Effects of Ketoanalogues on the Evolution of Renal Function and Bone Mineral Disorders in Patients with Advanced Chronic Kidney Disease: A Pilot Study. 酮类似物对晚期慢性肾脏病患者肾功能和骨矿物质紊乱演变的有益影响:一项试点研究。
IF 3.2 3区 医学
Annals of Nutrition and Metabolism Pub Date : 2024-01-01 Epub Date: 2024-07-21 DOI: 10.1159/000540472
Georgios Kosmadakis, Aura Necoara, Fanny Fuentes, Nathalie Ramade, Julien Baudenon, Clemence Deville, Ioana Enache, Claudine Gueret, Abraham Haskour
{"title":"Beneficial Effects of Ketoanalogues on the Evolution of Renal Function and Bone Mineral Disorders in Patients with Advanced Chronic Kidney Disease: A Pilot Study.","authors":"Georgios Kosmadakis, Aura Necoara, Fanny Fuentes, Nathalie Ramade, Julien Baudenon, Clemence Deville, Ioana Enache, Claudine Gueret, Abraham Haskour","doi":"10.1159/000540472","DOIUrl":"10.1159/000540472","url":null,"abstract":"<p><strong>Introduction: </strong>The supplementation with Ketoanalogues in patients on very low-protein diets has shown a favorable effect on the evolution of renal function. The aim of the present study was to evaluate the progression of renal function in advanced chronic kidney disease patients on a low-protein diet (<0.8 g/kg/d) with or without additional Ketoanalogues.</p><p><strong>Methods: </strong>The primary criterion is the evolution of the renal function at 6, 12, and 24 months for the two groups. The secondary criteria comprise the evolution of the body weight, mean blood pressure, 24-h proteinuria, salt and protein consumption, energy consumption, hemoglobin levels, serum albumin, prealbumin, C-reactive protein, liver function tests, serum electrolyte and phosphate levels, parathormone as well as calcium levels at the same time periods.</p><p><strong>Results: </strong>There was a significant nephroprotective effect of the Ketoanalogues after 12 and 24 months with no differences in the protein consumption between the two groups. Mean blood pressure, hemoglobin levels, 24-hour proteinuria, serum electrolyte, liver function tests, salt and protein consumption, and serum albumin and prealbumin did not present any significant differences. Serum bicarbonate and calcium levels were higher while serum phosphate and parathormone levels were lower in the Ketoanalogue group at all follow-up time points. During the 24-month follow-up period, 4 patients from the Ketoanalogue group and 8 patients from the control group quit the study.</p><p><strong>Conclusion: </strong>A low-protein diet supplemented with Ketoanalogues exerts significant nephroprotective effects and better bone mineral metabolism parameters compared to a low-protein diet only.</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":" ","pages":"315-322"},"PeriodicalIF":3.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FINUT 2024 Conference Abstracts. FINUT 2024 会议摘要。
IF 3.2 3区 医学
Annals of Nutrition and Metabolism Pub Date : 2024-01-01 Epub Date: 2024-10-21 DOI: 10.1159/000541491
{"title":"FINUT 2024 Conference Abstracts.","authors":"","doi":"10.1159/000541491","DOIUrl":"https://doi.org/10.1159/000541491","url":null,"abstract":"<p><p>This supplement compiles most of the special lectures, symposia sessions, oral communications, and poster communications abstracts of the FINUT 2024 Conference, taking place in Medellin Colombia on October 24-26, 2024, under the motto \"Nutrition at the forefront of a sustainable planet\" This third edition of the FINUT Conference has as a specific objective the continuity of the space for the exchange and discussion of ideas and integration of new teams in which all the stakeholders that influence the areas of food, nutrition, health, and sustainability in Ibero-America participate to face the main challenges of the region, and thus offer solutions aimed at improving the health status of the population, considering the impact of social inequalities in Ibero-America. The scientific program of the FINUT 2024 Conference includes 45 parallel symposia, 10 special lectures, 4 \"with-science\" meals, and the presentations of 41 oral communications and 210 poster communications. The four main thematic areas of the Conference are: • Healthy nutrition in the life cycle and clinical nutrition • Nutritional epidemiology and public health challenges in Ibero-America • Safe, healthy, sustainable, and social nutrition • Methods and tools in nutrition The Ibero-American Nutrition Foundation (FINUT) which was established in 2011. FINUT is a non-profit and financially self-supporting entity; our vision is to promote research and training, identify problems of public interest and provide scientific answers; and involve all stakeholders in our cause. Every other year the FINUT Conference allows us to meet in person with the FINUT community and continue the education, information, and research activities in food sciences, nutrition, and health that are carried out virtually daily. We are deeply grateful to the Organizing Committee, the Local Committee, and all the entities represented therein, for their commitment and effort, the Scientific Committee members for their dedicated work and participation in the scientific program, and the University of Antioquia for their interest in hosting this event in Medellin and for all the support received by its authorities, directors, and professors during the organization and execution of the event. We thank all the sponsors who have supported and participated in carrying out this science-based, international event. Our most sincere thanks to the delegates (professionals, academics, researchers, clinicians, and students) who have once again trusted FINUT and who, with their participation, have made it possible to showcase scientific development in food, nutrition, health, and sustainability of the Ibero-American region at the FINUT Conference. ¡See you at the FINUT 2026 Conference!</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":"80 Suppl 2 ","pages":"8-183"},"PeriodicalIF":3.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Large Neutral Amino Acids Moderate the Effects of Metabolic Syndrome on Cognitive Performance in Middle-Aged Adults. 大分子中性氨基酸缓和代谢综合征对中年人认知能力的影响
IF 3.2 3区 医学
Annals of Nutrition and Metabolism Pub Date : 2024-01-01 Epub Date: 2024-03-26 DOI: 10.1159/000538273
Cherry Youn, Marie L Caillaud, Yanrong Li, Isabelle A Gallagher, Barbara Strasser, Dietmar Fuchs, Hirofumi Tanaka, Andreana P Haley
{"title":"Large Neutral Amino Acids Moderate the Effects of Metabolic Syndrome on Cognitive Performance in Middle-Aged Adults.","authors":"Cherry Youn, Marie L Caillaud, Yanrong Li, Isabelle A Gallagher, Barbara Strasser, Dietmar Fuchs, Hirofumi Tanaka, Andreana P Haley","doi":"10.1159/000538273","DOIUrl":"10.1159/000538273","url":null,"abstract":"<p><strong>Introduction: </strong>Two large neutral amino acids (LNAA), tryptophan and tyrosine, are precursors to cerebral neurotransmitters and are involved in cognitive function. Higher levels of LNAA in young adults are associated with improved cognition, although these associations appear to reverse over time. Given that exposure to metabolic syndrome (MetS) may induce premature cognitive aging, the current project aims to fill the gap in the literature by examining the effect of LNAA on cognitive performance in midlife adults with metabolic risks.</p><p><strong>Methods: </strong>Eighty-eight adults, ages 40-61 years, participated in this cross-sectional study. LNAA metabolites were quantified, MetS components were measured using high-performance liquid chromatography, and MetS components were assessed in the laboratory. Composite verbal memory and executive functioning scores were computed using principal component analysis. We used linear regression models to test the interaction between LNAA and MetS while covarying for sex, age, and education.</p><p><strong>Results: </strong>The kynurenine/tryptophan ratio moderated the relation between MetS and verbal memory, even after adjusting for relevant covariates. Tyrosine metabolites were not significant moderators of the association between MetS and executive functioning.</p><p><strong>Conclusion: </strong>Our findings suggest that the detected weaker memory performance in adults with a high number of MetS components may be related to relative tryptophan depletion and possible decreases in serotonin production. Further investigation is warranted to examine the potential role of LNAA in associations between cognitive performance and metabolic risks over time.</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":" ","pages":"226-234"},"PeriodicalIF":3.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140292616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of a School-Based Intervention on Sugar-Sweetened Beverage Intake Substitution by Water in Mexican Scholars. 以学校为基础的干预措施对墨西哥学生以水替代含糖饮料摄入量的影响。
IF 3.2 3区 医学
Annals of Nutrition and Metabolism Pub Date : 2024-01-01 Epub Date: 2024-03-04 DOI: 10.1159/000538142
Laura Gabriela Téllez Olvera, Lilia Castillo Martínez, Bárbara da Silva Nalin de Souza, Rosely Sichieri, Liliana Ruíz Arregui, Wendy D Rodríguez Garcia, Guadalupe Silvia García de la Torre
{"title":"Impact of a School-Based Intervention on Sugar-Sweetened Beverage Intake Substitution by Water in Mexican Scholars.","authors":"Laura Gabriela Téllez Olvera, Lilia Castillo Martínez, Bárbara da Silva Nalin de Souza, Rosely Sichieri, Liliana Ruíz Arregui, Wendy D Rodríguez Garcia, Guadalupe Silvia García de la Torre","doi":"10.1159/000538142","DOIUrl":"10.1159/000538142","url":null,"abstract":"<p><strong>Introduction: </strong>The prevalence of overweight and obesity in children has increased in recent years, associated with substituting plain water intake with sugar-sweetened beverages. The aim of the study was to evaluate the impact of a school-based intervention that aimed to replace sugar-sweetened beverages with water on Mexican scholars.</p><p><strong>Methods: </strong>We included 314 children aged 9-11 from three public schools of the State of Hidalgo, Mexico, randomized to intervention (two schools from the municipality of Apan; six classes with 146 participants) or control group (one school from the municipality of Emiliano Zapata; six classes with 168 participants) and followed for 6 months. The intervention consisted of placing drinking fountains at schools and classrooms with nutritional education lessons to increase water consumption and decrease sugar-sweetened beverages. Mixed models for repeated measures were used to assess the impact of the intervention.</p><p><strong>Results: </strong>At the end of the study, water consumption was higher (200 mL/day, p = 0.005), and flavored milk consumption was lower (94 mL/day, p = 0.044) in the intervention group compared with the control group. There was also a statistically significant reduction in energy (p = 0.016) and sugar intake (p = 0.007).</p><p><strong>Conclusions: </strong>The school-based intervention favorably modified the consumption pattern of sugar-sweetened beverages and water in Mexican students.</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":" ","pages":"136-142"},"PeriodicalIF":3.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140027254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Growth Patterns of 11-29-Month-Old Children Consuming Young Child Formula: Secondary Analysis of a Randomized, Controlled Study. 食用幼儿配方奶粉的 11 至 29 个月大儿童的生长模式:随机对照研究的二次分析。
IF 3.2 3区 医学
Annals of Nutrition and Metabolism Pub Date : 2024-01-01 Epub Date: 2024-04-26 DOI: 10.1159/000539037
Outi Sirkka, Jacques Bindels, Pantipa Chatchatee, Pensri Kosuwon, Way S Lee, Nipat SimaKachorn, Maya Marintcheva-Petrova, Marieke Abrahamse-Berkeveld
{"title":"Growth Patterns of 11-29-Month-Old Children Consuming Young Child Formula: Secondary Analysis of a Randomized, Controlled Study.","authors":"Outi Sirkka, Jacques Bindels, Pantipa Chatchatee, Pensri Kosuwon, Way S Lee, Nipat SimaKachorn, Maya Marintcheva-Petrova, Marieke Abrahamse-Berkeveld","doi":"10.1159/000539037","DOIUrl":"10.1159/000539037","url":null,"abstract":"<p><strong>Introduction: </strong>The impact of young child formula (YCF) consumption on children's growth, particularly under suboptimal conditions, has scarcely been studied. In the current study, weight-for-age (WAZ), length-for-age (LAZ), and BMI-for-age (BAZ) z-score development was evaluated in children from five different countries (n = 668) who participated in a double-blind, randomized, controlled trial.</p><p><strong>Methods: </strong>The children (1-3 years old) were randomized to one of two intervention YCFs (with presence or absence of prebiotics and n-3 LCPUFAs) during 52 weeks of intervention. Additional stratified analyses evaluated the growth patterns of underweight, overweight, or stunted children.</p><p><strong>Results: </strong>No apparent differences in anthropometric measurements were observed between the intervention groups. In both YCF intervention groups, mean WAZ, LAZ and BAZ development was indicative of adequate growth during the intervention period. Stratified analyses showed stable WAZ and BAZ development among children with a healthy weight or overweight at baseline. Among underweight and stunted children, normalization in mean weight (∼1 SD) and length (∼0.8 SD) gain, respectively, was observed.</p><p><strong>Conclusion: </strong>The current study suggests that consumption of YCF, either or not containing prebiotics and n-3 LCPUFAs, is associated with adequate growth among young children. This association may depend on the child's baseline nutritional status. Future studies to assess the potential role of YCF in supporting adequate weight/length gain among children at risk for undernutrition are warranted.</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":" ","pages":"211-225"},"PeriodicalIF":3.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140847052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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