Annals of Nutrition and Metabolism最新文献

{"title":"IUNS-ICN Message","authors":"Hisanori Kato, Nobuko Murayama, J. Delarue, J. A. Martínez","doi":"10.1159/000530788","DOIUrl":"https://doi.org/10.1159/000530788","url":null,"abstract":"","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":"79 1","pages":"12 - 13"},"PeriodicalIF":3.9,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47226407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FINUT 2022 Conference Abstracts; October 9-11, 2022.","authors":"","doi":"10.1159/000526958","DOIUrl":"10.1159/000526958","url":null,"abstract":"<p><p>The following document is dedicated to compiling the abstracts of the communications and lectures of the FINUT 2022 Conference. The document comprises 111 abstracts of the guest speakers participating in the scientific symposia and special lectures and more than 230 abstracts for oral and poster communications, representing more than 20 countries. FINUT Conferences seek to open a place for contrasted science shared by the Ibero-American region, a necessary space to open opportunities and to display the research work done in Food and Nutrition. The main objective of the FINUT 2022 Conference is to create a space for the exchange and discussion of ideas related to the main challenges of Food and Nutrition in Iberoamerica, in order to offer solutions aimed at improving the health status of populations, taking into account the impact of social inequalities in the region. The scientific program of the Conference includes 40 parallel symposia, 5 breakfasts with the experts, and 11 special lectures. In this second edition the Conference focused on 4 topics: • Healthy Nutrition in the Life Cycle and Clinical Nutrition • Nutritional Epidemiology and Public Health Challenges in Iberoamerica • Safe, Healthy, Sustainable, and Social Food • Methods and Tools in Nutrition The entity organizing the Conference is the Ibero-American Nutrition Foundation (FINUT) which was established in 2011. FINUT is a non-profit and financially self-supporting entity; our vision is to promote research and training, identify problems of public interest and provide scientific answers; and involve all stakeholders in our cause. We work throughout the year in many scientific virtual activities with a large number of beneficiaries and the FINUT Conferences give us the opportunity to meet them personally. We wish to thank the Organizing, Scientific, and Local Committees for the enthusiasm and commitment dedicated to this conference, our sponsors for trusting us again, and take the opportunity we offer them to contact the most valuable part of our event, the delegates; professionals, academics, clinicians, researchers, and students in the areas of Food, Nutrition, and Health, to whom we also extend our most sincere gratitude. ¡See you at FINUT 2024!</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":"79 1","pages":"49-218"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating THBS1: A Risk Factor for Nonalcoholic Fatty Liver Disease in Obese Children.","authors":"Min Li,&nbsp;Lujie Liu,&nbsp;Yurong Kang,&nbsp;Shanlong Huang,&nbsp;Yanfeng Xiao","doi":"10.1159/000527780","DOIUrl":"https://doi.org/10.1159/000527780","url":null,"abstract":"<p><strong>Introduction: </strong>Thrombospondin 1 (THBS1) is a highly expressed adipokine in adults with obesity. In the present study, we aimed to investigate the clinical significance of THBS1in children with obesity and nonalcoholic fatty liver disease (NAFLD) and determine the effect of metformin on THBS1 expression in dietary-induced obese (DIO) mice.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 78 obese children and 35 nonobese children. Anthropometric parameters, clinical data, and circulating THBS1 levels were measured. The expression of THBS1 was detected in the serum and liver tissue from diet-induced obese mice (C57BL/6) with or without metformin treatment.</p><p><strong>Results: </strong>Higher THBS1 levels were observed in children with NAFLD and higher SDS-BMI. Individuals in the higher THBS1 quartile had a higher prevalence of hypo-high-density lipoprotein cholesterol (HDL-C). Logistic regression analysis showed a significant correlation between THBS1 and NAFLD, as well as between hip circumference and leptin levels. Receiver-operating characteristic (ROC) analysis revealed that THBS1 was a more sensitive predictor of NAFLD than leptin. Additionally, metformin ameliorated hepatic steatosis and decreased hepatic THBS1 expression in high-fat diet (HFD)-fed mice.</p><p><strong>Conclusions: </strong>Circulating THBS1 level may be a risk factor for NAFLD in obese children. Our findings provided a novel approach of metformin administration for the prevention and treatment of NAFLD. This study also confirmed that metformin decreased the expression of hepatic THBS in DIO mice.</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":"79 1","pages":"16-28"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9305319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of Concern.","authors":"","doi":"10.1159/000529287","DOIUrl":"https://doi.org/10.1159/000529287","url":null,"abstract":"","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":"79 2","pages":"107"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10400815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"European JRC Report: One More Stone for the (Scientific) Building of Nutri-Score.","authors":"Serge Hercberg,&nbsp;Pilar Galan,&nbsp;Mathilde Touvier","doi":"10.1159/000527852","DOIUrl":"https://doi.org/10.1159/000527852","url":null,"abstract":"No.","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":"79 1","pages":"3-4"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9305324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of Concern.","authors":"","doi":"10.1159/000529248","DOIUrl":"https://doi.org/10.1159/000529248","url":null,"abstract":"","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":"79 2","pages":"106"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10400361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Skeletal Muscle Mass and Bone Mass at Different Sites in Older Adults.","authors":"Lingyan Chen, Jiayu Wu, Weiying Ren, Xi Li, Man Luo, Yu Hu","doi":"10.1159/000528585","DOIUrl":"10.1159/000528585","url":null,"abstract":"<p><strong>Introduction: </strong>It has been well recognized that sarcopenia is closely related with osteoporosis, while the relationship between bone mass at different sites and muscle mass remains largely unexplored. This study aims to explore the relationship between bone mass at different sites and skeletal muscle mass in older adults.</p><p><strong>Methods: </strong>A total of 228 patients over 65 years old were enrolled in this study, and then 180 valid participants with accessible dual-energy X-ray absorptiometry (DXA) scanning data and absence of malignant tumors, mobility disorders, serious liver and kidney disease, and cardiac insufficiency were selected (138 male and 42 female). These individuals were further divided into control group and low skeletal muscle mass index (SMI) group. DXA scanning was used to access skeletal muscle mass and bone mass. SMI or body mass index was defined as appendicular muscle mass or weight divided by squared height, respectively. Low SMI <7.0 kg/m2 in male or <5.4 kg/m2 in female was defined as low SMI; while the bone density score at or below 2.5 standard deviations (T-score) below normal peak bone values, was regarded as osteoporosis.</p><p><strong>Results: </strong>The average age of enrolled patients was 82.72 years; the ratios of osteoporosis, low SMI, and low SMI with osteoporosis were 48.8%, 23.3%, and 15.0%, respectively. Compared with the control group, the prevalence of osteoporosis was higher, and the total bone mass and bone mass at various sites including limbs, spine, and pelvis, were all lower in low SMI group. Correlation analysis showed that SMI was positively related with total bone mass and bone mass at various sites. Covariance analysis showed that only total bone mass and appendicular bone mass decreased with decreasing SMI. After multiple adjustment, osteoporosis was positively related with the prevalence of low SMI, as evidenced by logistic regression analysis (odds ratio = 1.33, 95% confidential interval: 1.04-3.24, p = 0.045). Furthermore, compared with the highest quartile of appendicular bone mass, the lowest quartile was related with the increasing prevalence of low SMI (odds ratio = 7.29, 95% confidential interval: 1.21-67.45, p = 0.042).</p><p><strong>Conclusion: </strong>Compared with the other sites, the bone mass reduction at limbs of older adults was positively associated with skeletal muscle loss. It may be more beneficial to increase bone mass at the limbs for improved sarcopenia prevention and therapy. Further investigations are needed to explore the effects of other confounders (e.g., energy, calcium and vitamin D intake, and physical activity) on the osteoporosis and sarcopenia in older adults.</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":"79 2","pages":"256-262"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10043251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total Energy Expenditure in Healthy Ambulatory Older Adults Aged ≥80 Years: A Doubly Labelled Water Study.","authors":"Kay Nguo, Helen Truby, Judi Porter","doi":"10.1159/000528872","DOIUrl":"10.1159/000528872","url":null,"abstract":"<p><strong>Introduction: </strong>The life expectancy of older adults continues to increase; however, knowledge regarding their total energy requirements is lacking. This study aimed to compare the total energy expenditure (TEE) of older adults ≥80 years measured using doubly labelled water (DLW), with estimated TEE. The hypothesis was that the Mifflin, Ikeda, and Livingston equations will more closely estimate energy requirements than the commonly used Schofield equation.</p><p><strong>Methods: </strong>Resting metabolic rate (RMR) and TEE were measured using the reference methods of indirect calorimetry and DLW, respectively. Bland-Altman plots compared measured RMR and TEE with predicted RMR using equations (Mifflin, Ikeda, Livingston, Schofield) and predicted TEE (predicted RMR × physical activity level).</p><p><strong>Results: </strong>Twenty-one older adults (age range 80.7-90.1 years, BMI 26.1 ± 5.5 kg/m2) were included. The Schofield equation demonstrated the greatest bias from measured RMR, overestimating approximately up to double the mean difference (865 ± 662 kJ/day) compared with the three other equations. The Schofield equation exhibited the greatest bias (overestimation of 641 ± 1,066 kJ/day) compared with measured TEE. The other three equations underestimated TEE, with the least bias from Ikeda (37 ± 1,103 kJ/day), followed by Livingston (251 ± 1,108 kJ/day), and Mifflin (354 ± 1,140 kJ/day). Data are mean ± SD.</p><p><strong>Conclusions: </strong>In older adults ≥80 years, the Ikeda, Mifflin, and Livingston equations provide closer estimates of TEE than the widely used Schofield equation. The development of nutrition guidelines therefore should consider the utilization of equations which more accurately reflect age-specific requirements.</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":"79 2","pages":"263-273"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10045263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1159/000533253","DOIUrl":"10.1159/000533253","url":null,"abstract":"","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":" ","pages":"410"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10050859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Sleeve Gastrectomy on Skeletal Muscular Fat Infiltration Measured by MRI in Patients with Metabolic Syndrome: Preliminary Results.","authors":"Qiang Ma, Xiaoyue Cheng, Xinmeng Hou, Yuanyuan Yan, Chenglin Zhao, Zhenghan Yang","doi":"10.1159/000527941","DOIUrl":"10.1159/000527941","url":null,"abstract":"<p><strong>Introduction: </strong>Several researchers have focused on the role of skeletal muscle in metabolic problems in recent years. We aimed to evaluate influence of sleeve gastrectomy on skeletal muscular fat infiltration determined by magnetic resonance imaging in patients with metabolic syndrome (MetS).</p><p><strong>Methods: </strong>Sixty five MetS patients (male/female, 20/45; mean age, 35.5 years ± 6.6 [standard deviation]; age range, 22-59 years) enrolled in our study. Prior to and 1 year after sleeve gastrectomy, patients underwent routine measurement of skeletal muscular fat concentration (denoted by proton density fat fraction, PDFF) and chemical indexes. The associations of skeletal muscular fat concentration with other variables were determined using multiple linear regression analysis.</p><p><strong>Results: </strong>Difference between skeletal muscular PDFF at baseline (4.46 ± 2.01%) and PDFF 1-year after sleeve gastrectomy (3.00 ± 1.47%) was significant. Multivariable predictors of baseline skeletal muscular PDFF by descending order of standardized coefficient were fasting serum glucose (0.459; p = 0.001), age (0.395; p < 0.001), systolic pressure (0.319; p = 0.029), insulin (0.030; p = 0.026), white cell count (0.302; p = 0.007), diastolic pressure (-0.301; p = 0.046), and total alkaline phosphatase (-0.474; p < 0.001) all at baseline. Furthermore, multivariable predictors of change in PDFF were serum total cholesterol (3.510; p < 0.001), total alkaline phosphatase (0.535; p < 0.001), estrogen (0.457; p < 0.001), diastolic pressure (0.352; p < 0.001), systolic pressure (-0.409; p < 0.001), high-density lipoprotein cholesterol (-0.719; p < 0.001), insulin (-0.774; p < 0.001), C-reactive protein (-0.900; p < 0.001), triglyceride (-1.756; p < 0.001), and low-density lipoprotein cholesterol (-2.854; p < 0.001) all at baseline.</p><p><strong>Conclusion: </strong>Sleeve gastrectomy could alleviate myosteatosis in MetS patients during 1-year follow-up. The extent of remission on skeletal muscular fat infiltration after sleeve gastrectomy was influenced by baseline metabolic problems related to serum glucose, serum lipid, and blood pressure level.</p>","PeriodicalId":8269,"journal":{"name":"Annals of Nutrition and Metabolism","volume":"79 2","pages":"246-255"},"PeriodicalIF":3.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10417695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}