Annals of the New York Academy of Sciences最新文献_第3页

Time spent alone and loneliness in Mexican‐origin youth: The role of social relationships and personality 墨西哥裔青年的独处时间和孤独感：社会关系和个性的作用

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-05-01 DOI: 10.1111/nyas.15348

Geneva M. Jost, Sally Hang, Anna C. Wysocki, Mijke Rhemtulla, Richard W. Robins, Camelia E. Hostinar

{"title":"Time spent alone and loneliness in Mexican‐origin youth: The role of social relationships and personality","authors":"Geneva M. Jost, Sally Hang, Anna C. Wysocki, Mijke Rhemtulla, Richard W. Robins, Camelia E. Hostinar","doi":"10.1111/nyas.15348","DOIUrl":"https://doi.org/10.1111/nyas.15348","url":null,"abstract":"Loneliness is a pressing public health concern, particularly among adolescents and young adults. This preregistered study examined changes in time spent alone from 7th to 12th grade, as well as relationship and personality predictors of time spent alone in adolescence and loneliness in early adulthood, using data from a longitudinal study of 674 Mexican‐origin youth in the United States, a rapidly growing yet understudied demographic. Time spent alone showed linear increases from 7th to 12th grade, with greater increases in time spent alone in high school for youth who spent a high proportion of time alone at the start of high school (9th grade). Greater time spent alone in 9th grade was significantly predicted by gender, lower peer relationship quality, parent–child support, parental warmth, higher parent–child conflict, parental hostility, and youth neuroticism. However, there were no significant predictors of change in time spent alone throughout the course of high school (from 9th to 12th grade). Lastly, loneliness in young adulthood was predicted by spending a high proportion of time alone, higher neuroticism, and lower extraversion in the 9th grade. Thus, time spent alone in adolescence may be a crucial early indicator of later loneliness.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"56 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143893576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mass spectrometry reveals age‐dependent collagen decline in murine atria 质谱分析显示小鼠心房年龄依赖性胶原蛋白下降

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-29 DOI: 10.1111/nyas.15341

Nathalie Ringström, Charlotte Edling, Giovanna Nalesso, Javier Barallobre‐Barreiro, Kamalan Jeevaratnam

{"title":"Mass spectrometry reveals age‐dependent collagen decline in murine atria","authors":"Nathalie Ringström, Charlotte Edling, Giovanna Nalesso, Javier Barallobre‐Barreiro, Kamalan Jeevaratnam","doi":"10.1111/nyas.15341","DOIUrl":"https://doi.org/10.1111/nyas.15341","url":null,"abstract":"The cardiac atrial extracellular matrix (ECM) is central to age‐associated cardiac remodeling and subsequent decline in cardiac functioning. Despite this, the composition of the atrial ECM and how it changes with age is not yet known. This study utilized mass spectrometry to evaluate the composition of murine atria in young (12 weeks) and old (77 weeks) C57BL/6J mice. The tissue was decellularized, ECM and ECM‐associated proteins were extracted with GuHCl, and proteins were deglycosylated to enable identification of glycosylated peptides. Two hundred and thirty‐seven ECM and ECM‐associated proteins were found to be significantly differentially expressed with age. Some proteins (MMP9, S100A9, VWA3A, CTSD, CCL8) were more than threefold increased with age, proteoglycans were modestly decreased, while the overall collagen content was markedly decreased. STRING network mapping of physical associations predicted that both PLOD3 and PDGFA interact with the collagens that decreased with age. The results suggest that the mechanism behind age‐associated atrial stiffness is not due to an increase in collagen content as previously believed, but an increase in cross‐linking, potentially facilitated by PLOD3. Additionally, several of the significant proteins have not previously been associated with cardiac aging and thus are potential drug targets for age‐associated cardiac fibrosis and other age‐associated conditions.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"35 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143884602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of artificial intelligence in general, and large language models specifically, for understanding addictive behaviors 人工智能在理解成瘾行为方面的作用，特别是大型语言模型

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-29 DOI: 10.1111/nyas.15337

Christian Montag, Haibo Yang, Anise M. S. Wu, Raian Ali, Jon D. Elhai

引用次数: 0

Detecting loneliness among late adolescents: Validation and testing of a detection tool based on the UCLA Loneliness Scale 晚期青少年孤独感的检测：基于UCLA孤独感量表的检测工具的验证与测试

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-28 DOI: 10.1111/nyas.15316

Anne Bo, Berit Kjærside Nielsen, Astrid Fyrstenborg Christensen, Julie Christiansen, Pamela Qualter, Mathilde Graulund Severinsen, Mathias Lasgaard

{"title":"Detecting loneliness among late adolescents: Validation and testing of a detection tool based on the UCLA Loneliness Scale","authors":"Anne Bo, Berit Kjærside Nielsen, Astrid Fyrstenborg Christensen, Julie Christiansen, Pamela Qualter, Mathilde Graulund Severinsen, Mathias Lasgaard","doi":"10.1111/nyas.15316","DOIUrl":"https://doi.org/10.1111/nyas.15316","url":null,"abstract":"The high prevalence of loneliness among adolescents, combined with their tendency to conceal it, highlights the need for strategies that identify and support those youth who experience loneliness. This study aimed to validate and test a detection tool for late adolescents within educational settings in Denmark. The tool, which was based on nine items from the UCLA Loneliness Scale (UCLA-9), underwent a three-stage refinement and testing process. In Stage 1, psychometric analyses and cognitive interviews investigated the reliability, validity, and usability of the tool among adolescents ages 16–20 years; potential cut-off scores for identification of cases on the three-dimensional scale were explored. Stage 2 involved a feasibility test in three educational institutions. Field observations and qualitative interviews with participants offered insights and recommendations for implementation of the tool in educational settings. Stage 3 involved 1728 students engaged in the Danish Lift program run in three municipalities. Among those youth, the refined UCLA-9 demonstrated robust psychometric properties, identifying 9% of adolescents as cases with a cut-off score of ≥10 on each subscale. The UCLA-9 showed promise in identifying adolescents experiencing loneliness, which often co-occurred with poor mental health. Challenges remain in determining appropriate cut-off scores for the identification of cases.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"9 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143885024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to “Neurostimulation improves reading and alters communication within reading networks in dyslexia” 对“神经刺激提高阅读能力并改变阅读网络中的交流”的更正

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-28 DOI: 10.1111/nyas.15361

引用次数: 0

Using the process model of eco-anxiety in group work 小组工作中生态焦虑的过程模型

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-28 DOI: 10.1111/nyas.15344

Panu Pihkala

{"title":"Using the process model of eco-anxiety in group work","authors":"Panu Pihkala","doi":"10.1111/nyas.15344","DOIUrl":"https://doi.org/10.1111/nyas.15344","url":null,"abstract":"Group work is regarded as an especially promising method for engaging with eco-anxiety and other difficult eco-emotions. This article introduces a new method for facilitated group work based on the process model of eco-anxiety and ecological grief (hereafter, the process model). The method combines elements from timeline exercises, social learning, spectrum line methods, and somatic methods. Observations and feedback from a pilot workshop are used to develop the method further. Participants explored their eco-anxiety journeys in small groups. The phases and dimensions of the process model were printed on paper, and people could move in space while they reflected on them. The participants were encouraged to experiment with somatic movements and sounds. The possible balance or imbalance between action, distancing (including self-care), and grieving (including other emotional engagement) was explored. The workshop ended with creative co-thinking about how to find more balance. This method was clearly useful for the participants, but more research is needed to explore its use with different audiences. This method can be facilitated by people other than therapists if they have suitable skills, but it also allows for in-depth use in therapy and psychological interventions. Variations of using the method or parts of it are discussed.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"40 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143885025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Natural mutants in mammalian facial morphology: A review of palate clefting in bats 哺乳动物面部形态的自然突变：蝙蝠腭裂的研究综述

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-27 DOI: 10.1111/nyas.15353

Greta M. Keller, Karen E. Sears

引用次数: 0

A network analysis of statistics anxiety symptoms and their antecedents in UK higher education students 英国高等教育学生焦虑症状及其前因的统计网络分析

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-27 DOI: 10.1111/nyas.15350

Joshua J. March, David Hamilton, Dawn McCormack, Ross Brisco, Amy Grech

{"title":"A network analysis of statistics anxiety symptoms and their antecedents in UK higher education students","authors":"Joshua J. March, David Hamilton, Dawn McCormack, Ross Brisco, Amy Grech","doi":"10.1111/nyas.15350","DOIUrl":"10.1111/nyas.15350","url":null,"abstract":"Statistics anxiety is a widespread, multifaceted phenomenon affecting many students in higher education. Feelings of excessive worry when exposed to statistical content impact student performance and heighten negative perceptions of statistics. While many factors have been identified as relevant antecedents of statistics anxiety, it is unclear how they relate to different components of this phenomenon, and which factors are most influential. Additionally, no research has investigated the impact of peer attitudes toward statistics anxiety. The current study describes a preregistered network analysis of statistics anxiety, peer attitudes, and related variables with a sample of 279 UK higher education students. After performing reliability checks, results support the distinction made in previous literature between attitudes toward statistics and statistics anxiety per se. The former were influenced by feelings of statistics self-efficacy, age, and peer attitudes toward statistics, and the latter was influenced by negative problem orientation and intolerance of uncertainty. The most influential nodes were the negative problem orientation variables, inhibitory anxiety, and interpretation anxiety. The findings are discussed in relation to addressing statistics anxiety from multiple angles.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"1547 1","pages":"220-232"},"PeriodicalIF":4.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/nyas.15350","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143880230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extraesophageal reflux: Clinical manifestations and tools for diagnosis and treatment 食管外反流：临床表现及诊断和治疗工具

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-27 DOI: 10.1111/nyas.15349

Simon Blaine-Sauer, Jonathan Bock, Serhat Bor, Jacqueline Allen, Derrick R. Randall, Sumeet Mittal, Thomas L. Carroll

{"title":"Extraesophageal reflux: Clinical manifestations and tools for diagnosis and treatment","authors":"Simon Blaine-Sauer, Jonathan Bock, Serhat Bor, Jacqueline Allen, Derrick R. Randall, Sumeet Mittal, Thomas L. Carroll","doi":"10.1111/nyas.15349","DOIUrl":"10.1111/nyas.15349","url":null,"abstract":"Extraesophageal reflux is a complex clinical entity, classically presenting with laryngopharyngeal symptoms including chronic cough and vocal changes, but it is also implicated in conditions such as subglottic stenosis and lung injury. Diagnosis is challenging, in large part due to the oftentimes vague presenting symptoms with multiple possible etiologies, as well as limited consistency of currently available diagnostic tests. Furthermore, effective medical treatment is limited, and acid suppression therapy such as proton pump inhibitors has shown low to mixed efficacy in relieving signs and symptoms of reflux outside the esophagus. In this review, we will address laryngopharyngeal reflux and its diagnosis based on symptoms and exam findings, and diagnostic tools such as impedance monitoring and salivary pepsin testing. A summary of the use and limitations of acid-suppressing therapies for extraesophageal reflux and the rationale for targeting pepsin as a nonacid component of reflux will be presented. Finally, the current literature on the potential role of reflux in subglottic stenosis and lessons learned regarding reflux in the lung transplant surgery field in higher risk patient populations will be discussed.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"1547 1","pages":"233-244"},"PeriodicalIF":4.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143880251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Latexin and calretinin together define a novel excitatory neuron subclass in the claustrum of the short-tailed fruit bat, Carollia perspicillata 在短尾果蝠（Carollia perspicillata）的屏状体中，乳胶蛋白和calretinin共同定义了一种新的兴奋性神经元亚类

IF 5.2 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-04-27 DOI: 10.1111/nyas.15346

Timothy Morello, Richard Kollmar, Mark Stewart, Rena Orman

{"title":"Latexin and calretinin together define a novel excitatory neuron subclass in the claustrum of the short-tailed fruit bat, Carollia perspicillata","authors":"Timothy Morello, Richard Kollmar, Mark Stewart, Rena Orman","doi":"10.1111/nyas.15346","DOIUrl":"https://doi.org/10.1111/nyas.15346","url":null,"abstract":"The claustrum is a telencephalic structure with inputs from and outputs to many other brain structures. This central arrangement has motivated research on the claustrum's role in cognition and highlights the need to understand its intrinsic connectivity. In the fruit bat, Carollia perspicillata, the large size of the claustrum offers access to its intrinsic structure. Previously, we defined the structure of the C. perspicillata claustrum with antibodies against latexin as an excitatory cell marker and against calcium-binding proteins as inhibitory cell markers. Using this immunohistochemical method, we have now identified an unexpected cell type with concurrent latexin and calretinin immunoreactivity. The calretinin+ neurons of the claustrum, including those that coexpress GAD67 (another inhibitory cell marker) and those that coexpress latexin, are located in the claustral shell subregion. Neuronal latexin+/calretinin+ somata are smaller than either latexin−/calretinin+ or latexin+/calretinin− somata. Since latexin labels glutamatergic neurons in multiple brain areas and has never been found to colocalize with GAD, we conclude that the latexin+/calretinin+ neurons in the claustral shell are excitatory. They represent one of three excitatory cell types that are identifiable in the claustral shell and demonstrate that calretinin can label both inhibitory and excitatory cells in the C. perspicillata claustrum.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"7 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143880218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0