Annals of Medical Research最新文献

{"title":"Prognostic factors and the role of adjuvant radiation therapy in Non-melanoma skin cancer: Retrospective, A single-center experience","authors":"Emine Y lmaz","doi":"10.5455/annalsmedres.2023.03.068","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.03.068","url":null,"abstract":"Objective: Non-melanoma skin cancer (NMSC) is the most prevalent malignancy worldwide, with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) representing the most common types of NMSC. In this retrospective analysis, patients with NMSC who had adjuvant radiotherapy (RT) had their treatment results and prognostic variables evaluated. Material and Methods: A total of 115 patients with NMSC who had adjuvant RT in our clinic during January 2006 and September 2021 were assessed. The average age was 74 years, and the male to female ratio was 1.95:1. (range: 25–95). The most often diagnosed kind of NMSC was SCC (93%, n=107), preceded by BCC (7%, n=8). The extremities (17.4%, n=20), the trunk (1.7%, n=2), and the head and neck area (80.9%, n=93) were where the bulk of NMSC lesions were discovered. Results: The mean follow-up period was 60.7 months (the range was 4.2–194.7); metastases were found in six patients (5.2%), and locoregional recurrence was identified in 24 patients (20.8%). The 3- and 5-year total survival percentages were 71.2% and 59.3%, respectively, and the median overall survival (OS) time was 87.1 months. Tumor size and surgical margin status were linked to a worse OS in multivariate analysis of prognostic variables (hazard rate [HR]=3.0, 95% confidence interval [CI]: 1.8-5.2; p=0,001 and HR=2.4, 95% CI: 1.4-4.1; P=0,002, respectively). Conclusion: Postoperative RT is an efficient, acceptable therapeutic option for NMSC in high-risk individuals. Our results suggest that surgical margin and tumor size were independent predictors of OS in NMSC patients; nevertheless, future studies including more patients are required to corroborate these results.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"149 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79391280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Cardiology Consultation at Long-Term Video EEG Monitoring","authors":"A. M. Res, C. Gunbey, H. Aykan, T. Karagoz, G. Turanlı, M. Topçu, D. Yalnızoǧlu","doi":"10.5455/annalsmedres.2022.09.281","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.09.281","url":null,"abstract":"Objective: In children, a broad range of paroxysmal events, including syncope and arrhythmias, may mimic true epileptic seizures. When a definitive diagnosis could not be established, long-term video electroencephalogram monitoring (LTVEM) should be taken into consideration. Furthermore, epilepsy patients have a higher rate of cardiac comorbidities. The purpose of this study is to evaluate the rationale and results of the pediatric cardiology consultations in patients admitted to the LTVEM unit. Methods: We retrospectively analyzed the files of children who were admitted to LTVEM unit and consulted with the pediatric cardiology department between January 2006 and May 2014. The patients who had both echocardiography and 24-hour ambulatory electrocardiogram monitoring were included. Results: Among 70 children, 74.3% (n: 52) were classified as having epilepsy, 21.4%. (n: 15) with nonepileptic events, and 4.3% (n: 3) could not be classified. In epilepsy group, 21 children (40.4%) were consulted with pediatric cardiology due to rhythm disturbances detected during LTVEM, the remaining consultations (59.6%) were due to history of known cardiac diagnosis (arrythmias n: 2, structural/congenital heart disease: 5), tuberosclerosis (n: 6), drop attacks (n: 5), murmur (n: 5), and other reasons. The cardiac evaluation revealed previously undetected arrhythmia (n:3) and mitral valve prolapse (n:1) in four patients with epilepsy. In addition to the pre-existing long QT syndrome, one child experienced his typical attack, subsequently he was diagnosed as epilepsy. The remaining group consisted of 18 children, with syncope being the most common diagnosis for consultation (n: 10, 55.5%). Conclusion: Our study revealed that a subgroup of children with epilepsy had cardiovascular comorbidities. Additionally, epilepsy was confirmed in some patients who already had cardiac problems. Pediatricians should be aware of potential mimickers of epilepsy and note that epilepsy and cardiac problems may also co-exist. Correct diagnosis and appropriate treatment are crucial in this patient group.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84876967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Rate of Locomotor System Disability in Patients Undergoing Electroneuromyography","authors":"Zeynep nal, Z. Bahtiyarca, D. Cankurtaran, Ece z","doi":"10.5455/annalsmedres.2023.06.135","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.06.135","url":null,"abstract":"Aim: It was aimed to evaluate the characteristics of the patients who were referred to our electroneuromiyography (ENMG) Laboratory to evaluate the rate of locomotor system disability from the Disabled Health Board (DMB). Materials and Methods: Patients aged 18 years and over who applied to our hospital's DMB in the last three years (01.01.2019-31.12.2021) and were referred to the ENMG Laboratory to determine the disability rates related to the locomotor system were included. With the retrospective analysis, demographic characteristics of the patients, ambulatory levels, etiological factors, reasons for applying to the ENMG Laboratory, and diagnoses in ENMG reports were noted. Results: Files of 1306 patients were reviewed, ENMG was performed in 139 (10.64%). The mean age was 45.34±12.2 years. One-hundred and eleven (79.9%) patients were male and 28 (20.21%) were female. Eighteen (12.9%) of the patients needed an assistive walking device. The most common etiological factors in locomotor system disability was disc herniation in 24 (17.2%) patients. The most common preliminary diagnosis was peripheral nerve injury in 67 (48.2%) patients. Peripheral nerve injury was the most frequently reported pathology in ENMG reports with 52 (37.4%) patients. While the ENMG report of 26 (18.7%) patients was normal; entrapment neuropathy was found in 14 (10.1%) patients, polyneuropathy in 10 (7.2%) patients, plexopathy in 8 (5.8%) patients, and cranial neuropathy in 1 (0.7%) patient. Conclusion: Peripheral nerve injuries are the most common pathology in both preliminary diagnosis and ENMG reports. ENMG provides information such as the location and the severity of the lesion, so electrodiagnostic tests are very important in the evaluation of locomotor system disability.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84546342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the Effects of Direct Current Stimulation on Parkinson Disease in vitro","authors":"Bet man, M-W Rul, Bet ek, A. Lu, M. z","doi":"10.5455/annalsmedres.2023.05.108","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.05.108","url":null,"abstract":"Objective: Parkinson’s disease (PD) is a progressive, neurodegenerative disease associated with the loss of dopaminergic neurons. Multiple possible mechanisms such as oxidative stress, mitochondrial dysfunction or excitotoxicity caused by glutamate are thought to mediate neuronal loss in PD. It is stated that transcranial direct current stimulation (tDCS) has positive effects on PD, but underlying mechanisms are still largely undefined. So, in this study, the effects of tDCS on PD and the relationship of these effects with glutamate and NMDA levels were investigated. Materials and Methods: To induce the PD model, 6-OHDA (200 µM) was administered to SH-SY5Y cells for 24 hours. Electrical stimulation was applied to the SH-SY5Y cells at 20 minutes and 7 hours after 24 hours. The effect of tDCS on cell viability was investigated by MTT 3-(4, 5-Dimethylthiazol-2-yl) method. Glutamate and NMDA receptor levels were measured using commercial kit. Results: It has been observed that 6-OHDA increases cell death in SH-SY5Y cells, while electrical stimulation reverses this effect. While 6-OHDA increased the glutamate level, tDCS therapy reversed this effect. No significant difference was found between the groups in NMDA levels. Conclusion: Our findings suggest that tDCS can be a functional therapy on PD by reducing glutamate toxicity.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"55 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80695516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A DEFICIENCY OR DEVELOPMENTAL DEFECT IN PANETH CELLS MAY LEAD TO ACUTE APPENDICITIS IN CHILDREN","authors":"B. Harma, F. Tecellioglu","doi":"10.5455/annalsmedres.2023.02.041","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.02.041","url":null,"abstract":"Objective The aim of this study was to investigate whether there were differences in the Paneth cells between children with acute appendicitis (AA) and those with normal appendix (NA), and to reveal the distribution of and morphological changes in Paneth cells in appendix inflammation. Materials and Methods The data of 63 patients who underwent appendectomy diagnosed with acute appendicitis between January 2021 and December 2022, including age, gender, operative diagnosis, and postoperative histopathological examination results, were analyzed retrospectively. To evaluate the distribution and changes of Paneth cells throughout AA and NA groups, samples with hematoxylin and eosin (H & E)-stained sections were obtained from the Department of Histopathology's archives. Selected blocks were stained with Masson-Trichrome. The number of Paneth cells and the degree of granular density in the appendicitis tissues were statistically evaluated and compared with the results of the control group. Results A total of 63 appendectomies were performed, including 31 incidental appendectomies and 32 performed for preoperative diagnosis of acute appendicitis. There were no statistically significant differences between the groups that underwent surgery for AA and the NA in terms of gender and age (p>0.05). It was observed that the number of Paneth cells and granule density decreased significantly in acute appendicitis (AA) group (p<0.05). Conclusion Reduction or developmental deficiency in Paneth cells, which results in the loss of protective secretion, may increase the appendix's susceptibility to bacterial infection by allowing organisms to adhere and move across the mucosa. Such enhancement of infection may contribute to the pathogenesis of appendicitis.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"306 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77778378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of selective arterial calcium stimulation test in the diagnosis of the hyperinsulinemic hypoglycemia","authors":"Yasemin nsal, zen l, S. Cander, Co Ate, E. Aydemir, Oktay nsal, C. Ersoy, Erdin rk","doi":"10.5455/annalsmedres.2022.11.339","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.11.339","url":null,"abstract":"We examined the patients with hyperinsulinemic hypoglycemia who were performed non-invasive imaging techniques with doubtful or failed results. We compared the performances of the Selective Arterial Calcium Stimulation Test (SACST) and non-invasive imaging techniques. Eight patients with hyperinsulinemic hypoglycemia, performed SACST after evaluating with imaging modalities were examined retrospectively. Three patients were diagnosed with Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome (NIPHS), 4 with insulinoma, and 1 with autoimmune hypoglycemia after SACST. While the concordance between the SACST and surgery-proven pathology for insulinoma was 50% (2/4), the accuracy in the localization of insulinoma was 25%. Although SACST does not have high concordance with surgery-proven pathology and accuracy in the localization of insulinoma, it may be preferred in the differential diagnosis of hyperinsulinemic hypoglycemia in medical centers where other imaging techniques are not available, or in cases where other imaging methods obtain suspicious/inadequate diagnosis.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82238551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional results of patients with femoral intertrochanteric fractures who underwent surgery of proximal femoral nail or bipolar hemiarthroplasty – a comparative study","authors":"mit N, mer Ayik","doi":"10.5455/annalsmedres.2022.08.247","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.08.247","url":null,"abstract":"ABSTRACT Purpose: In this study, the functional results of patients with femoral intertrochanteric fractures who underwent surgery were compared with their clinical features in terms of proximal femoral nail ( PFN ) and bipolar hemiarthroplasty ( BPH ). Methods: PFN (Group 1) was implanted in 40 of 89 patients (44 female, 45 male) aged between 51-80 (mean 68,16 ± 6,78) whereas BPH (Group 2) was used with 49 patients. Age, gender, fracture mechanism, additional disease, Body mass index (BMI), Albumin level, Hemoglobin (Hb) decrease level, T-score, American Society of Anesthesiologists (ASA) classification, type of anesthesia, surgery type, operation time, hospital stay and full weight-bearing time, the scores of Harris Hip Function (HHS), the social function of Jensen (JSF), Parker-Palmer mobility (PPMS) in preoperative and postoperative periods, and postoperative complications were all recorded. Results: In group 1; patients were younger, operation time was 46.78 ± 5.29 minutes and hospital stay was 2.48±0.75 days, which were shorter compared with group 2. For group 1, most surgery types were closed, T-score was -2.49±0.59 and better, the time of full weight-bearing was 3.48±0.78 months, Hb decrease was 1.17±0.37 and less, and Albumin level was 3.11±0.4 g/dL and higher compared to group 2 (p<0.05). HHS was better in the BPH group at the sixth month (p<0.05). In group 1, the 12th, and 24th months scores of JSF were better, PPMS was higher in all evaluations (p<0.05). Operation time, ASA, T-score, albumin correlate with functional scores, while BMI and Hb did not. Conclusion: Many factors are important for progressing patients with intertrochanteric femur fractures toward a functional level. Considering these parameters in patients with femoral intertrochanteric fracture , PFN or BPH can both be used for treatment according to the surgeon's preference.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81437820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CONSERVATIVE TREATMENT AND FOLLOW-UP FOR ACUTE APPANDICITIS: IS EMERGENT SURGERY NECESSARY ?","authors":"S. Karakas","doi":"10.5455/annalsmedres.2022.10.310","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.10.310","url":null,"abstract":"Introduction: Emergent operation is the accepted standart therapy of acute appendicitis. But conservative medical therapy is an emerging solution for acute appendicitis. We aimed to publish the conservative treatment experience of Inonu University Medical School, Department of General Surgery. Material and Method: Between January 2020 and January 2022, patients who had a clinical suspicous acute appendicitis with an Abdominal Ultrasonography or a computer tomography reporting a term ’appendicitis’ that referred to Emergency or General Surgery Department and also had a medical therapy with a non-operative approach were detected in the hospital data system. Patient demographics and clinical data analysed retrospectively. Results: Fifteen patients were detected within the 2 years period that had been received medical therapy for acute appendicitis. Median age was 32.0 (min:19 - max:70), median appendix diameter was 7.2 mm (min:5.5 - max:11.0). One patient was died due to Non-Hodgkin Lymphoma after 16 days of diagnosis of acute appendicitis. None of the patients required an operation during surveillance. Most frequent reasons for conservative treatment were not eliminating the diagnosis of pelvic inflammatory disease, inflammatory intestinal disease and urinary tract infections. Discussion and Conclusion: While some comorbidities can go along with acute appendicitis such as cardiac and systemic haematologic diseases, some of them mimic acute appendicitis such as pelvic inflamatory disease or inflamatory bowel diseases. Especially elder patients, who have a suspicous case, with a low CRP and Neutrophilia counts with an uncomplicated appendicitis, may benefit from antibiotherapy. More patients, that had an appendectomy history need to be evaluated on this aspect.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90450382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can prenatal online education improve pregnancy outcomes compared to classic education?","authors":"Kemal Din, zlem Deveci","doi":"10.5455/annalsmedres.2022.12.379","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.12.379","url":null,"abstract":"Aim: Cesarean section rates have increased, and although various measures such as antenatal education programs have been introduced to correct this, these could not be performed face-to-face due to the COVID-19 pandemic, and were largely carried out online. This study was planned to determine the effect on the rate of cesarean deliveries and pregnancy outcomes of classic education received in the antenatal period and its online replacement in such and similar extraordinary situations. Material and Method: The research was designed as a retrospective, cohort study. Fifty women undergoing childbirth in our hospital and who received online antenatal education (Group 1), 101 women who received classic education (Group 2), and 77 women receiving no education (Group 3) took part in the study. Patient data were retrieved from the hospital information system and patient records. Results: This study involved 228 pregnant women. Fifty pregnant women (22%) receiving antenatal online education were assigned to Group 1, 101 women (44%) receiving classic face-to-face education to Group 2, and 77 women (34%) receiving no education to Group 3. Forty percent of Group 1, given online education, and 62.4% of Group 2, given classic education, were able to give birth via the normal vaginal route, and the difference was statistically significant (0.001). Cesarean delivery rates were significantly higher in Group 1 (60%) than in Group 2 (37.6%) (0.001). Statistically similar results were determined in all three groups in terms of birth weight, birth length, and low birth weight. No significant difference was also observed between the three groups in terms of premature birth (<37 weeks) (p=0.67). Conclusion: Online antenatal education does not reduce cesarean delivery rates compared to classic education. However, neonatal outcomes are similar.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90517562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Correlations between Interleukin-6 and 10 Levels and Mortality in Patients with Sepsis","authors":"Oya Akkaya, Nurser Mutlu, R. Koylu, N. Akilli, O. Koylu, Mehmet Eryilmaz","doi":"10.5455/annalsmedres.2022.08.234","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.08.234","url":null,"abstract":"Aim: The aim of this study was to investigate the associations between the serum levels of interleukin (IL)-6, IL-10, tumor necrosis factor (TNF)-α, IL-6/IL-10 ratio and Glasgow Coma Scale (GCS), Acute Physiology and Chronic Health Evaluation (APACHE-II), Sequential Organ Failure Assessment (SOFA) scores and mortality in patients with sepsis. Materials and Methods: The sample of the study consisted of 50 patients (median age: 75 years) presented to the Intensive Care Unit of the Emergency Department between January 2019 and December 2019 with sepsis. Blood samples were taken from all patients on day 1 and day 3. The IL-6, IL-10, TNF-α levels, APACHE-II, SOFA, and GCS scores were recorded on a data collection form. Results: The deceased and the survived groups significantly differed in day-1 (p = 0.013) and day-3 IL-6 (p = 0.016) levels, day-1 IL-6/IL-10 ratio (p = 0.029) and gender. On the other hand, there was no significant difference between the groups in day-1 and day-3 IL-10 levels and day-3 IL-6/IL-10 ratio. The GCS score was significantly lower in the deceased group than in the survived group (p < 0.05). Conclusion: High IL-6 levels and high IL-6/IL-10 ratios on the day of diagnosis with sepsis were found to be correlated with mortality. IL-6 level may be particularly useful for predicting mortality if used in combination with scoring systems such as the GCS and different clinical parameters.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89836791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}