Annals of Medical Research最新文献

{"title":"THE EFFECT OF RADIOFREQUENCY ELECTROMAGNETIC RADIATION ON RAT LIVER TISSUE AND SERUM PARAOXONASE (PON1)","authors":"Mehmet YAVA, Asuman T","doi":"10.5455/annalsmedres.2023.08.210","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.08.210","url":null,"abstract":"Aim: The development of technology increases the rate of everyone having a smartphone. Therefore, the possible biological effects of these devices are of concern. In this study, we aimed to investigate the effect of 2100 MHz radiofrequency electromagnetic radiation on rat liver tissue and serum paraoxonase 1 level.\u0000Materials and Methods: Within the scope of the study, a 2100 MHz radiofrequency electromagnetic radiation model was created. In our study, we used Sprague Dawley male rats. Two groups were made as sham-control and exposure group (5 h a day for 2 weeks). Liver tissue and serum paraoxonase were studied.\u0000Results: The paraoxonase 1 value of the exposure group was higher than the sham control group, and did not have statistically important difference in the comparison of exposure and sham control groups (p>0.05). Did not have important difference in histopathological parameters of rat liver tissue (p>0.05). \u0000Conclusion: Although it seems that radiofrequency radiation does not cause liver damage, more detailed studies with short- and long-term exposure are needed.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134980763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"pandemic process in children","authors":"Ferda enol, ilkay eci, Altay Babacan, Nuray Arslan, Zulal Toraman","doi":"10.5455/annalsmedres.2023.01.033","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.01.033","url":null,"abstract":"Aim: When compared to adults, it is seen that the COVID-19 disease in children has a milder course. However, considering that there are cases with severe course and even death, it is aimed to analyze the COVID-19 PCR positivity in children according to age and gender. Materials and Methods: Between March 7, 2020 and August 18, 2021, throat and nose swab samples from children with clinical complaints or a history of contact were evaluated by reverse transcriptase polymerase chain reaction (RT-PCR) and the distribution of positive children by age and gender classified. Results: The PCR test was positive in 3,181 (30.74%) out of 10,342 children, the highest positivity rate was 33.52% in male and in the 15-18 age range, while this rate was 36.77% in female in the 15-18 age range. Conclusion: In this study, it was determined that the prevalence of the COVID19 pandemic, which affected the whole world, in childhood age groups was highest in male and between the ages of 15-18.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134980779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE IMPORTANCE OF OBSTRUCTIVE SLEEP APNEA SCORE AND END-TIDAL CO2 LEVEL IN ADOLESCENT CHILDREN WHO UNDERWENT OROPHARYNGEAL SURGERY","authors":"Hayel zer, lker m, Tolga zl","doi":"10.5455/annalsmedres.2023.09.240","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.09.240","url":null,"abstract":"Aim Children with obstructive sleep apnea have an increased postoperative risk of adverse respiratory events. In our study, we calculated Obstructive Sleep Apnea Scores using the modified STOP-Bang questionnaire in children undergoing oropharyngeal surgery. The groups determined according to this score were compared in terms of mask ventilation levels in the intraoperative period, postoperative complications and postoperative ETCO2 levels. Methods A total of 90 patients, aged 7-15 years, who will undergo oropharyngeal surgery, classified as ASA I-II, and who have undergone a modified STOP-Bang questionnaire at the preoperative examination, were included in the study. Obstructive sleep apnea score (OSAs) was determined according to the modified STOP-Bang questionnaire, and the patients were divided into 3 groups as low, medium, and high-risk. Difficult mask ventilation level was noted in the intraoperative period. At the end of the operation, end-tidal carbon dioxide concentration (ETCO2) values at 0, 3, 5, 10, and 15 minutes after the patient was extubated and whether the patient had spasms were recorded. Results Among the 8 parameters in the modified STOP-Bang questionnaire, it was found that there was a significant difference between the groups for the other 6 parameters except for snoring and learning disability. Diffucult mask ventilation increased significantly from Group I to Group III. There is a significant difference between Group I and II, Group II and III, and Group I and Group III (p= 0.001). Although there were small differences within the groups and between the measurements of ETCO2 at different minutes, these differences were not statistically significant (p≥0.05) Conclusion In conclusion, associations between the results of the modified STOP-Bang questionnaire and the level of intervention required for difficult mask ventilation, this information could serve as a useful indicator for a higher level of care in the perioperative period for future patients","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134981038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Could SCUBE be used as a therapeutic target in rheumatoid arthritis?","authors":"NUR YAVUZ, ERHAN APKIN, ASIM REM, AHMET E, D ALTAY","doi":"10.5455/annalsmedres.2023.07.165","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.07.165","url":null,"abstract":"Objective: To investigate the levels of signal peptide-CUB-EGF domain-containing protein(SCUBE 1 and 3) in rheumatoid arthritis (RA). Materials and Methods: Twenty eight RA patients and 28 healthy volunteers were included in the study. SCUBE-1, SCUBE-3, Vascular Endothelial Growth Factor (VEGF), Matrix Metalloproteinase-9 (MMP-9), CD-40L, Interleukin-6 (IL-6) levels, which are important markers in angiogenesis, were measured twice, at baseline and after the treatment. Results: Compared to the healthy group, only MMP-9, one of the angiogenesis markers, was elevated in the patient group (p>0.05). After treatment, a significant decrease was observed in VEGF levels (p<0.05), while SCUBE-1, SCUBE-3, IL-6, CD-40 and MMP-9 levels remained at similar levels (p>0.05). Conclusion: In our study, RA patients responded to treatment with clinical improvements. Although there were differences in the levels of MMP and VEGF, there was no association with the disease in SCUBE.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135159964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Demographic Characteristics of Patients with Neuro-ophthalmological Disorders Starting Later in Life","authors":"Sevim KAVUNCU, Pinar Nalcacioglu","doi":"10.5455/annalsmedres.2022.12.374","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.12.374","url":null,"abstract":"Objectives: To determine the demographic, etiological and clinical features as well as treatment modalities of patients with neuro-ophthalmological disorders starting at a later age. Materials and Methods: We retrospectively reviewed the clinical data related to the neuro-ophthalmology patients who presented at the age of ≥ 65 years at two tertiary eye care referral centers from 2004 to 2022. Results: Of the 2,127 patients who applied to the Neuro-Ophthalmology Department during this period, 162 (7.6%) were ≥ 65 years old at the time of diagnosis and their data were analyzed. The mean age at the onset of disease was 73.2 ± 6.7 (65–95) years, and mean follow-up time was 1.1±0.4 (1-3) years. Non-arteritic anterior ischemic optic neuropathy (NAAION) (n=85, 52.5%), isolated cranial nerve palsies (n=28, 17.3%), and cerebral vascular disorders (CVD) (n=14, 8.6%) were the most frequent diagnosis. The most common symptoms were as follows: sudden visual loss in 79 (48.8%), diplopia in 31 (19.1%), and blurred vision in 21 (13%) cases. The most common accompanying systemic disease was hypertension (HT) and diabetes mellitus (DM) in 31 (27.4%), followed by HT in 29 (25.7%) cases. There was no accompanying systemic disease in 49 (30.2%) patients. The diagnosis of NAAION and AAION resulted in poor visual outcomes, while CVD presented with homonymous hemianopsia. Conclusion: NAAION and CVD were the most common age-related neuro-ophthalmological disorders that cause visual acuity loss and a visual field defect at an advanced age. Identifying these disorders and managing the visual problems are essential to preserve the protection of the patient's quality of life.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136303079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Partial anomalous pulmonary venous connection: diagnosis, management, and outcomes","authors":"Fatma Sengul, Perver Arslan, Ensar Duras, Pelin Ayyildiz, Hacer Kamali, Okan Yildiz, smihan Onan, Alper Guzeltas","doi":"10.5455/annalsmedres.2023.06.144","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.06.144","url":null,"abstract":"Aim: Partial anomalous pulmonary venous connection (PAPVC) is a rare congenital cardiovascular anomaly characterized by one or more, but not all, pulmonary veins draining into the right atrium. This condition can occur in isolation or in conjunction with other cardiac abnormalities such as an atrial septal defect (ASD). In this study we aimed to investigate the clinical presentation, diagnostic approaches, management options, and outcomes of patients with PAPVC. Materials and methods: This retrospective study included 140 patients diagnosed with isolated or ASD-associated PAPVC between January 2010 and December 2022. Results: The median age at presentation was 5 years (1 month to 39 years). Isolated PAPVC was observed in 36 patients (25.7%), while 104 patients (74.3%) had an atrial septal defect (ASD). In our patient cohort, 119 patients (85%) exhibited partially affected anomalous PVs, while the remaining 21 patients (15%) presented with anomalous pulmonary veins involving the entire lung. Right-sided PVs were involved in 116 patients (82.8%), left-sided PVs in 20 patients (14.3%), and both right and left PVs in 4 patients (2.9%). Malposition of primum septum was detected in 8 patients (5.8%), and scimitar syndrome was present in 7 patients (5%). Surgical treatment was performed in 71.4% (n=100) of the patients, while catheter angiography with vertical vein occlusion was performed in 2 patients with dual drainage. Conclusion: Despite the infrequency and complexity of PAPVC, timely identification and customized surgical intervention can help avert serious complications. The application of advanced imaging technologies in diagnosis and surgical planning is crucial.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136303080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the effects of implant locations and overdenture designs on the implants and bone stress: a finite element analysis","authors":"Elifnur zelce, E. Tokar, zg Karacaer","doi":"10.5455/annalsmedres.2022.08.235","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.08.235","url":null,"abstract":"Objective The effects of implant locations and prosthesis design (palate less, full palate) on stress values of the implant and bone in maxillary overdenture prostheses were examined and compared with finite element analysis. Material and Methods Full palate and palate less four implant supported finite element overdenture models have created with different implant locations (M1: bilateral lateral 1. premolar, M2: canine 2. premolar, M3: 1. premolar 1. Molar). Static loads have applied with food stuff method on 1. Molar region. Von mises stress on implants and implant parts, maximum and minimum principal stress generated in peri-implant bone have calculated with finite element analysis method (FEA). Results As a result, it was observed that the palate less design creates more stress on the implants and bone compared to the full palate design. In addition, stress formation was observed to be higher in models with implant positions are posterior. Conclusion In implant supported overdentures (ISO), palatal coverage ensures more balanced distribution of stresses occurring around the implants and implant parts, regardless of the location of the supporting implants.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88015670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancers Attributable to Smoking and Obesity in Turkey: a population-based study","authors":"D. Yuce, M. Hayran, S. Eser, F. Aksakal, S. Uner","doi":"10.5455/annalsmedres.2022.06.188","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.06.188","url":null,"abstract":"Objective: Cancers are the second most common cause of mortality following cardiovascular diseases in Turkey. Tobacco and obesity are the two major etiological factors for cancer progression, which are highly prevalent in Turkey. This study aimed to evaluate the new cancer cases in Turkey attributable to these two main risk factors. Material and methods: The tobacco-related cancers based on the International Agency for Research on Cancer (IARC) monographs were esophagus, oral cavity, gastric, pancreatic, larynx, lung, renal, and bladder cancers, and the obesity-related cancers based on the IARC's and World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) Continuous Update Project's reports were esophagus, colon, rectum, gallbladder, pancreas, kidney, ovary, endometrium, and breast cancers. The cancer incidences were obtained from the national cancer statistics. A lag time of at least 10 years was regarded adequate to observe the effects of past exposures on the new cancer cases. Prevalence of tobacco smoking was based on Peto-Lopez approach, and the obesity prevalence was obtained from the National Burden of Disease and Cost-Effectiveness Project Household Survey, 2003 Report in Turkey. Using these incidence and prevalence data, we estimated the population-attributable fractions (PAF) of cancers attributable to smoking and obesity in Turkey. Results: For tobacco-related cancers, the highest PAFs were found in lung cancer (89.8%), larynx cancer (86%), oral cavity and pharynx cancer (77.2%) in males, and larynx cancer (46.5%), lung cancer (43%), and esophagus cancer (31.4%) in females. For obesity-related cancers, the highest PAFs were found in esophagus adenocarcinoma (31.4%), kidney cancer (19.8%), gallbladder cancer (15.1%) in males, and esophagus adenocarcinoma (33.9%), endometrium cancer (32.8%), and postmenopausal breast cancer (22.8%) in females. When all tobacco-related cancers were considered, 41283 cases in males and 3853 cases in females were attributable to tobacco smoking, and when all obesity-related cancer types were considered, the number of attributable cancer cases to obesity was 2653 in men and 7387 in women Conclusion: The current situation of avoidable cancer burden in Turkey shows that eliminating the tobacco smoking and obesity may result with preventing more than 50000 cancer cases in Turkey.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88144820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between positive mental health and activities of daily living in patients with stroke. \u0000\u0000Positive mental health in patients with stroke","authors":"Elif Ok, nci sa, Elif Ate, Birg zkan","doi":"10.5455/annalsmedres.2022.04.132","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.04.132","url":null,"abstract":"<jats:p />","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84236701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Title \u0000Causative agents distribution of isolated from dermatomycoses in Eskişehir city hospital \u0000\u0000\u0000Sort Title\u0000Superficial fungal infections","authors":"Rabiye nba, mer lu, Canan man","doi":"10.5455/annalsmedres.2022.09.271","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.09.271","url":null,"abstract":"Abstract Objective Dermatomycoses are superficial fungal infections of the skin, hair and nails. The fungi responsible for dermatomycoses include dermatophytes, yeasts and non-dermatophytic molds (NDM). Onychomycosis is the most common nail disease caused by dermatophytes, NDMs, and yeasts with a worldwide. This study was under taken to investigate the current distribution of aetiological agents of dermatomycoses. Materials and Methods In this study, we evaluated the microscopic examination and culture results of the samples taken from the patients who applied to our clinic for two year. Species were identification on the basis of combined clinical pictures, culture and microscopic morphology characters of together. Results During the study period, 592 samples were examined. The distribution of isolates was found to be 118 (47.2%) NDM, 66 (26.4%) dermatophytes and 66 (26.4%) yeasts, respectively. Tinea unguium was the most prevalent type of dermatophytoses. T. rubrum was most frequent aetiological agents of detected in patients. According to our study, 22% of non-dermatophyte hyaline molds are Fusarium spp. and 21% are Aspergillus spp. species. Conclusion Several studies have shown that both the prevalence and aetiology of dermatomycoses can change according to geographical location, climatic conditions, personal factors. The objective of our study was to analyse 2 years of epidemiological data regarding dermatological mycology testing performed in a large tertiary care teaching hospital in Eskişehir, This report represents the most comprehensive analysis of this type from Eskişehir, and it is hoped that its findings will be of interest to, and inform, researchers and clinicians focused on mycoses and international epidemiology. To the best of our knowledge, we provide the first analysis from Eskisehir of fungal detections from all external body site (skin, hair and nail).","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87388831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}