Annals of Medical Research最新文献

{"title":"Bibliometric analysis of primary central nervous system lymphoma","authors":"Serkan GUVEN, Sevil ALKAN","doi":"10.5455/annalsmedres.2023.08.171","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.08.171","url":null,"abstract":"Aim: Primary central nervous system lymphoma (PCNSL) is an important topic in hematology due to its rare, aggressive course, difficult diagnosis and special treatment requirements. This bibliometric analysis study aimed to examine PCNSL -related publications published since the last 2000 and to identify potential points of future research. Material and methods: Web of Science Core Collection documents published between 2000 and 2022 were analyzed using selected keywords. The obtained data were visualized with bibliometric tools. Publishing countries, organizations, journals, authors, references, and keywords were all examined comprehensively. Results: 1,160 articles on PCNSL published since 2000 were retrieved. These publications tend to focus on research in oncology (n=456, 39.310%), clinical neurology (n=354, 30.517%), and hematology (n=173, 14.914%). Search criteria revealed that 6,458 authors from 65 different countries and 1,570 organizations worldwide contributed to PCNSL articles. Conclusion: Studying research on PCNSL is crucial to improve our knowledge of this disease and to create new treatment strategies. It is very important to keep in mind that the characteristics and trends in PCNSL research may change over time as new findings and developments in the field are discovered.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"152 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135800290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of metastatic versus non-metastatic breast cancer at the time of diagnosis and risk factors for primary metastatic breast cancer","authors":"Mesut YUR","doi":"10.5455/annalsmedres.2023.08.184","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.08.184","url":null,"abstract":"Objective: The most common type of cancer in women is breast cancer. Despite an increase in the rate of early detection, distant organ metastasis is still seen at the time of diagnosis. The purpose of this study was to identify the predictive risk factors for breast cancer patients with distant organ metastases and to compare them to those without distant organ metastases. Materials and Methods: The study included data from patients who applied to our clinic for follow-up or treatment between January 2020 and July 2020. After meeting the exclusion criteria, the remaining 115 patients were included in the study. Study participants were divided into two groups: metastatic (group I) and non-metastatic (group II). Logistic regression analysis is used to assess the predictive risk factors. Results: There is a significant difference between groups in terms of the breast side, T-stage, N-stage, CA 15-3, and albumin levels (p< 0.05). In univariate analyses, T-stage, CA 15-3, estimates glomerular filtration rate (eGFR), alkaline phosphatase, and albumin levels were statistically found to be significant (p<0.05). In multivariate analysis, CA 15-3 (OR: 1.017; 95% CI: 1.005-1.030, p = 0.006), eGFR (OR: 0.944; 95% CI: 0.894-0.996, p = 0.034), and albumin (OR: 0.087; 95% CI: 0.011-0.676, p = 0.020) were found to be predictive risk factors for metastatic breast cancer. Conclusion: High T-stage, N positivity, high CA15-3 levels, and low albumin levels were observed in the metastatic breast cancer group. CA 15-3, eGFR, and albumin levels were found to be predictive factors for metastatic breast cancer at the initial diagnosis. New studies are needed to validate these findings.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135802054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Botulinum toxin-A injection improves motor recovery in patients with stroke","authors":"Arzu c, Selin Alp, lknur Akta, P nar, Feyza zkan","doi":"10.5455/annalsmedres.2023.05.124","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.05.124","url":null,"abstract":"Aim: Spasticity that occurs after a stroke may contribute to disability. Botulinum toxin type-A (BTX-A) injections are commonly used to manage spasticity. This study sought to determine the effectiveness of BTX-A injections on spasticity and motor recovery in patients with stroke. Materials and Methods: Twenty-five patients with stroke scheduled for BTX-A injection for spasticity were included in the study. The patients were analyzed in two groups: upper limb and lower limb group. A single dose of BTX-A was applied to the patients. Before, 2, and 12 weeks after BTX-A injections, motor function was assessed using Brunnstrom recovery stages, and spasticity was evaluated according to Modified Ashworth Scale (MAS). The lower limb group additionally underwent the Functional Ambulation Classification (FAC) and 10-meter walking test. Results: Mean age of patients was 54.96 ± 12.84 years. Eighteen patients were enrolled in the upper limb group and 23 in the lower limb group. Clinical evaluation of the upper limb group two weeks after injections demonstrated a significant decrease in shoulder adductor muscle MAS, elbow, wrist, and finger flexor muscles MAS, and a significant improvement in Brunnstrom recovery stages for the upper limb and hand (p<0.05). At week 12, spasticity decreased only for the shoulder adductor muscles. In the lower limb group, clinical evaluation at week 2 showed a decrease in the knee extensor and toe flexor muscles MAS. Assessment of the patients at week 12 found a significant improvement in Brunnstrom recovery stage for the lower limbs (p<0.05). There was no statistically significant recovery in the FAC and 10-meter walking test (p>0.05). Conclusion: This study supports that BTX-A injections are effective for improving spasticity and motor function in patients with stroke.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135839178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact Of Neutrophil-to-lymphocyte ratio (NLR), Derived neutrophil-to-lymphocyte ratio (dNLR), Systemic inflammation index (SII), Systemic inflammation response index (SIR-I), and Aspartate transaminase/platelet ratio (APRI) In Predicting Pregnancy Outcomes Of Inflammatory Bowel Disease","authors":"Dilek Beser, Izzet Ozgurluk, Deniz Oluklu, Esra z, Ozgur Kara, Atakan Tanacan, Dilek Sahin","doi":"10.5455/annalsmedres.2023.06.148","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.06.148","url":null,"abstract":"Objective: We aimed to investigate the effect of systemic inflammation indices in predicting pregnancy outcomes of inflammatory bowel disease (IBD). Materials and Methods: Pregnant women with Crohn’s disease (CD) and Ulcerative colitis (UC) were identified from hospital medical records. Demographic features, disease type, duration and activity, and obstetric outcomes such as gestational age, mode of delivery, birth weight, Apgar scores at the first and fifth minutes after birth, and neonatal intensive care unit admission were assessed. Laboratory tests were conducted in the first trimester, including complete blood count and liver function. Neutrophil/lymphocyte ratio (NLR), derived neutrophil/lymphocyte ratio (dNLR), systemic inflammation index (SII), systemic inflammation response index (SIR-I), and aspartate transaminase/platelet ratio (APRI) were measured. Results: The study involved 48 pregnant women, 26 diagnosed with UC and 22 with CD. At least one attack occurred in 31.3% of all patients during pregnancy. For predicting attacks during pregnancy, the optimal cutoff values of dNLR, NLR, SII, SIR-I, and APRI were 2.12 (86.7% sensitivity, 82.8% specificity), 2.89 (86.7% sensitivity, 81.8% specificity), 850.7 109/L (66.7% sensitivity, 63.6% specificity), 1.06 109/L (66.7% sensitivity, 72.7% specificity), 0.051 (80% sensitivity, 75.8% specificity), respectively. A cut-off value of 0.07 for APRI ( 71.4% sensitivity and 73.2% specificity) was calculated to predict low birth weight. Conclusion: NLR, dNLR, SII, SIR-I, and APRI might help predict attacks in pregnant women with IBD. In addition, APRI may be utilized to predict low birth weight in pregnant women with IBD.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135839181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous renal replacement therapy in intensive care: When is the optimal timing?","authors":"Murat lu","doi":"10.5455/annalsmedres.2023.09.242","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.09.242","url":null,"abstract":"Introduction: Acute kidney injury is one of the most widespread problems in critical patients in intensive care. It leads to severe morbidity and mortality. Although the indications for emergency dialysis are well known, the timing for initiating CRRT in the critical patient is still unclear. This study examines the effect on mortality of early CRRT by retrospectively scanning critical patients who received CRRT in intensive care. Material and Method: Demographic, clinical, and laboratory data were recorded by retrospectively scanning patients aged over 18, with no previously known chronic kidney disease, and receiving only CRRT, who were treated in intensive care over a one-year period. The patients were divided into two groups, an early group consisting of KDIGO stages 1 and 2, and a late group consisting of KDIGO stage 3. These were than examined in terms of 28-day mortality. Results: Forty-eight patients with a mean age of 65.94±19.61 years were included in the study. Twenty-eight (58.3%) patients were men. Cardiovascular diseases were the most frequent diagnoses, in 16 (33.3%) patients, and comorbidity was detected in 32 (66.7%). SOFA, blood urea nitrogen, creatinine, and procalcitonin values differed between the groups, but no difference was observed in 28-day mortality. Conclusion: The study results showed that early or late application of CRRT has no positive effect on survival, but further randomized studies on the subject are now needed.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135839406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Efficacy of Epidural Blood Patch and Transnasal Sphenopalatine Ganglion Block in the Treatment of Postspinal Puncture Headache","authors":"Ebru Canakci, Ilker Coskun","doi":"10.5455/annalsmedres.2023.08.200","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.08.200","url":null,"abstract":"Aim: Postspinal puncture headache (PDPH) affects postoperative recovery and patients' quality of life after surgery. PDPH is the most common complication of spinal anaesthesia that affects patients' well-being the most. The epidural blood patch (EBP) is the gold standard for interventional treatment of PDPH. Sphenopalatine ganglion block (SPGB), a new noninvasive method for treating PDPH, has come to the forefront. SPGB is noninvasive and very easy to perform compared with EBP. This study aims to compare the efficacy of the two interventional methods in treating PDPH. Material and Method: Between January 1, 2018, and February 1, 2023, 30 cases diagnosed with PDPH underwent EBP and 28 SPGB. Case demographics, type of surgery performed, whether complications occurred after the procedure, and the amount of acetaminophen taken within 24 hours were recorded in mg. The VAS scores were recorded 8 times, in the first half hour before and after surgery, and, 1, 2, 4, 6, 12 and 24 hours after the surgery. Results: There was no statistically significant difference between the distributions of sex, type of surgery, and amount of acetaminophen taken after surgery by groups (p values respectively p= 0.245, p=0.994, p=0.131 ). There was a statistically significant difference between the distributions of 4th-hour values VAS by group (p=0.008). There is a statistically significant difference between the groups' distributions of the values of the 6th-hour VAS (p=0.016). VAS scores were lower in the epidural blood patch group. There was no difference between the VAS scores in the blood patch and block group in all other measurement periods. Nevertheless, comparing the time variables of the groups, the main effect of time has a statistically significant impact on the VAS (p < 0.001). There was a significant difference in the sphenopalatine ganglion block and epidural blood patch groups when the pre-surgery VAS value was compared with all post-surgery periods (p < 0.001, p < 0.001). Conclusion: The epidural blood patch is the gold standard in treating postspinal headaches. However, it is a difficult procedure to perform since it is an invasive procedure. Sphenopalatine ganglion blockade is a treatment modality with very close efficacy to epidural blood patches in treating postspinal headaches. It can be used as an alternative treatment method in cases that do not accept treatment with the epidural blood patch. As postspinal headache mostly occurs in obstetrics patients, it can be safely used to protect a newborn mother and the baby from the side effects of drugs that pass into the breast milk.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135839412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Botulinum toxin-A in the treatment of upper facial wrinkles: efficacy comparison of different formulations","authors":"H L, Elif M, Zekayi KUTLUBAY","doi":"10.5455/annalsmedres.2023.09.251","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.09.251","url":null,"abstract":"Objective: It is suggested that different formulations of botulinum toxin-A (BoNT-A) used for the same indication might be a factor affecting patient satisfaction. This study aimed to assess patient satisfaction levels in treating upper facial wrinkles (UFW) using various BoNT-A formulations and their association with age and gender. Materials and Methods: This retrospective study included 600 UFW patients treated with different formulations of BoNT-A. The BoNT-A formulations included three different groups: onaBoNT-A (ONA, n:200), aboBoNT-A (ABO, n:200), and praBoNT-A (PRA, n:200).In the patient files or records, satisfaction levels from the BoNT-A application were scored as follows: 1: not satisfied, 2: slightly satisfied, 3: satisfied, 4: very satisfied, 5: completely satisfied. Results: The mean patient satisfaction scores were similar in the ONA and ABO groups, but higher in the PRA group (4.4±0.5 vs. 4.3±0.6 vs. 4.0±0.9, P <0.001, respectively). The mean satisfaction score of the patients aged 18-30 and those aged >60 were lower than the other age groups. Among all patients in the 41-50 age range, the patient satisfaction score was higher in the ONA group than the ABO and PRA group. In all female patients, the mean satisfaction score was lower in the PRA group compared to the ONA and ABO groups (P <0.001), Conclusions: While various BoNT-A formulations are generally associated with high patient satisfaction in the treatment of UFW, this can vary depending on age ranges and gender. Evaluating patient-related factors such as age and gender can contribute to the treatment planning for UFW and enhancing treatment adherence.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134981023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AN EXAMINATION OF THE OCULAR SURFACE PARAMETERS OF PATIENTS WITH NON-EXOPHTHALMIC GRAVES DISEASE","authors":"S. Keser, S. Kobat, E. Yusufoğlu, Fatma Savur, Sara Koylu Gungor","doi":"10.5455/annalsmedres.2023.03.065","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.03.065","url":null,"abstract":"<jats:p />","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78257058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the relationship between Google Trends search data and national suicide rates in Turkey","authors":"O. Ekinci, Fadime ay, Al Koyuncu, Feyza Soy, Or etin, Feyza ce","doi":"10.5455/annalsmedres.2023.04.083","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.04.083","url":null,"abstract":"Objective: The present study aimed to examine possible relationships between suicide-related terms obtained from Google Trends and actual suicide data and whether these relationships differ according to sex. Materials and Methods: The study period was from 2009 to 2019. In this study, suicide data were collected from the suicide statistics of the Turkish Statistical Institute (TUIK) for this timeframe. Google Trends was used to examine the search trends of suicide-related terms in Turkey. Pearson correlation analysis was used to find associations between the data obtained from TUIK and Google Trends. Finally, linear regression analysis was performed to identify predictors of monthly completed suicide rates in the general population. Results: In our study, 105 search terms obtained from Google Trends were examined to find associations with suicide rates in a specific timeframe. Among them, 31 terms had positive correlations, and nine had significant negative correlations. The terms \"allergy\" and \"pain\" were the most closely related to the overall suicide rates. Other significantly correlated terms were \"how to commit suicide,\" \"to commit suicide,\" \"depression,\" and \"hallucination.\" In addition, significantly different results were found for men and women. Conclusion: The present study showed that suicide-related terms obtained from Google Trends may predict actual suicide rates and may be an easy way to monitor suicide trends in Turkey. Future studies should use a more comprehensive internet network, including social media and other search engines, and consider other variables related to suicide to better understand this relationship.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74893100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the necessity of routine histopathological examination in tonsillectomy and/or adenoidectomy operations. Histopathology of tonsillectomy and/or adenoidectomy","authors":"A. M. Res, S. Kandemir, G. Pamuk, T. Yi̇ği̇t","doi":"10.5455/annalsmedres.2023.04.094","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.04.094","url":null,"abstract":"<jats:p />","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"117 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75760218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}