Annals of Surgical Oncology最新文献

{"title":"Invited Editorial on \"Association of Preoperative Gut Microbiota Disturbances With Postoperative Infectious Complications in Major Gastrointestinal Cancer Surgery: A Large-Scale Exploratory Study,\" by Sugimoto et al.","authors":"Ryan B Morgan, Michael G White","doi":"10.1245/s10434-025-18537-6","DOIUrl":"https://doi.org/10.1245/s10434-025-18537-6","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145298314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASO Author Reflections: How Fluorescence Navigation Transforms Splenic Perfusion Assessment in Warshaw Technique, from Uncertainty to Visualization.","authors":"Jianlin Lai, Shi Chen","doi":"10.1245/s10434-025-18597-8","DOIUrl":"https://doi.org/10.1245/s10434-025-18597-8","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145298313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASO Visual Abstract: Comparison of Two Wireless Localization Technologies for Removal of Nonpalpable Breast Lesions-SCOUT^® Radar Reflector and Pintuition^® Magnetic Seed.","authors":"Justine Chinn, Michelle Earley, Brittany Z Dashevsky, Kimberly Stone, Candice N Thompson, Jean Bao","doi":"10.1245/s10434-025-18560-7","DOIUrl":"https://doi.org/10.1245/s10434-025-18560-7","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145298347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review of Occult Malignancy and Sentinel Lymph Node Metastasis at the Time of Contralateral Prophylactic Mastectomy.","authors":"Jenna L Sturz-Ellis, Christopher D Vetter, Courtney N Day, Judy C Boughey","doi":"10.1245/s10434-025-18474-4","DOIUrl":"https://doi.org/10.1245/s10434-025-18474-4","url":null,"abstract":"<p><strong>Background: </strong>Occult malignancy (OM) identified in contralateral prophylactic mastectomy (CPM) presents a challenge for axillary management.</p><p><strong>Methods: </strong>This meta-analysis identified retrospective studies using PubMed, Embase, and Cochrane Reviews with the keywords OM and CPM. In this study, OM was defined as invasive disease only. To determine the proportion of OM and node positivity rates, MedCalc software was used.</p><p><strong>Results: </strong>The 27 studies in this meta-analysis included 5728 patients who underwent CPM, with OM identified in 87 patients. The pooled incidence of OM was 1.55%. Of the 73 patients with axillary staging details available, 41 patients with OM (56%) underwent surgical axillary staging. Of these 41 patients, 8 had a positive sentinel lymph node (SLN) (20%), and 4 of the 8 patients had subsequent axillary lymph node dissection (ALND) with no additional positive lymph nodes identified. For 64 of the 87 patients with OM, T category was available. Of these 64 patients, 62 (97%) had pT1 and 2 (3%) had pT2 carcinoma. Histologic subtype was available for 52 OMs. Of these, 39 (75%) were ductal, 8 (15%) were lobular, and 5 (10%) were other. Biomarkers were available for 33 OMs, of which 21 (64%) were luminal A, 3 (9%) were luminal B, 3 (9%) were luminal human epidermal growth factor receptor 2 (HER2), and 6 (18%) were triple-negative.</p><p><strong>Conclusions: </strong>Occult malignancy in CPM is uncommon (1.55%), and when it occurs, it is predominantly pT1, luminal A, or invasive ductal carcinoma. Occult malignancy with SLN metastasis occurs in only 0.1% of CPMs, and when present, SLN metastasis is low volume (≤2 nodes). This supports the current guideline recommendations against routine SLN surgery at the time of CPM.</p>","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic Resection of Type IV Perihilar Cholangiocarcinoma. Moving Toward the Most Complex Minimally Invasive Technique in Biliary Cancer Surgery.","authors":"Shivanshu Kumar, Sharona Ross, Iswanto Sucandy","doi":"10.1245/s10434-025-18514-z","DOIUrl":"https://doi.org/10.1245/s10434-025-18514-z","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Minimally invasive techniques are not being adopted in biliary cancer surgery for perihilar cholangiocarcinoma (Klatskin tumor) because of the technical complexity of tumor extirpation, the need for fine hepaticojejunostomy biliary reconstructions, and concerns about oncological radicality that could affect long-term survival. Although technical reports have been published for resections of type I-III Klatskin tumors using robotic approaches in the last 5 years, technical descriptions of resections of type IV Klatskin tumors are very limited in the literature.&lt;sup&gt;1-5&lt;/sup&gt; This is because type IV perihilar cholangiocarcinoma involves secondary biliary/hepatic ducts above the hilar plate bilaterally, requiring a very difficult resection, followed by more than one fine hepaticojejunostomy anastomoses. Thus, this operation is undertaken via an unpopular laparoscopic method. The emergence of minimally invasive robotic techniques, with their technical advantages over laparoscopy enables complex resections to be completed. Herein, we describe an application of a minimally invasive robotic biliary surgery technique for resection of type IV perihilar cholangiocarcinoma.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A 71-year-old otherwise healthy man initially presented to his medical oncologist with pruritus, obstructive jaundice, and weight loss. Workup, including computed tomography/magnetic resonance imaging scans, endoscopic ultrasonography, biliary endoscopy, endoscopic retrograde cholangiopancreatography, and positron-emitting tomography, revealed Bismuth-Corlette type IV perihilar cholangiocarcinoma without any evidence of extrahepatic disease. Preoperative drainage using bilateral endoscopic retrograde cholangiopancreatography stenting was completed with normalization of his liver function panel. The patient had undergone 1 year of systemic chemoimmunotherapy before the surgical referral. He showed no signs of disease progression and tolerable systemic side effects. The operative plan included robotic extended left hepatectomy en-bloc with caudate lobectomy, extrahepatic biliary resection, radical portal lymphadenectomy, and Roux-en-Y hepaticojejunostomy. The Pringle maneuver was not used in this operation because of the relatively hemostatic nature of the parenchymal division. However, isolated temporary vascular clamping of the main portal vein for 10 minutes was undertaken using a vascular bulldog clamp to facilitate and achieve left portal vein division, which was densely adherent to the hilar plate. 3-0 barbed permanent sutures were used for the bile duct closure and jejunojejunostomy anastomosis. 4-0 barbed absorbable sutures and 5-0 PDS sutures were used for the hepaticojejunostomy anastomoses.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The operation was completed uneventfully without intraoperative or postoperative complications. The patient's recovery in the hospital was uneventful, and he was successfully discharged on postoper","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASO Visual Abstract: The Combination of Chest Wall Perforator Flaps and Surgeon-Performed Breast Ultrasound: An Effective Synergy to Expand the Boundaries of Breast-Conserving Surgery.","authors":"Massimo Ferrucci, Francesco Milardi, Daniele Passeri, Elena Miglioranza, Paola Del Bianco, Giacomo Montagna, Alberto Marchet","doi":"10.1245/s10434-025-18484-2","DOIUrl":"https://doi.org/10.1245/s10434-025-18484-2","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASO Visual Abstract: The Association between Conducting a Multidisciplinary Team Conference and Short- and Long-Term Outcomes After Colorectal Cancer Surgery-A National Register Study.","authors":"Karoline Bendix Bräuner, Maliha Mashkoor, Mikail Gögenur, Viviane Lin, Carolin Oppermann, Ismail Gögenur","doi":"10.1245/s10434-025-18559-0","DOIUrl":"https://doi.org/10.1245/s10434-025-18559-0","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145298308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASO Visual Abstract: Trends in Patient-Reported Outcomes After Breast-Conserving Surgery and Partial-Breast Versus Whole-Breast Irradiation.","authors":"Julia M Chandler, Minji Kim, Varadan Sevilimedu, Tiana V Le, Jonas A Nelson, Lior Z Braunstein, Monica Morrow, Minna K Lee, Audree B Tadros","doi":"10.1245/s10434-025-18477-1","DOIUrl":"https://doi.org/10.1245/s10434-025-18477-1","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145298296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skeletal Muscle Gauge as a Prognosticator of Survival in Resected Early-Stage Non-small Cell Lung Cancer.","authors":"Arsalan A Khan, Wara Naeem, Minha Ansari, Oluwamuyiwa W Adebayo, Savan K Shah, Gillian C Alex, Nicole M Geissen, Michael J Liptay, Christopher W Seder","doi":"10.1245/s10434-025-18553-6","DOIUrl":"https://doi.org/10.1245/s10434-025-18553-6","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia has emerged as a prognostic biomarker in lung cancer, yet the optimal radiological metric for its assessment remains debated. Skeletal Muscle Gauge (SMG), a composite of muscle volume and density, may offer superior prognostic utility compared with individual measures.</p><p><strong>Patients and methods: </strong>We retrospectively analyzed 343 patients who underwent lung resection for clinical stage I-IIB NSCLC between 2010 and 2021 and had a preoperative positron emission tomography (PET) scan. Volumetric body composition metrics, skeletal muscle index, skeletal muscle area, skeletal muscle density (SMD), and SMG were derived from automated segmentation using PET scans followed by normalization. Associations with overall survival was assessed using Cox proportional hazards analyses. Predictive accuracy was evaluated using the concordance index. Optimal SMG cutoff was determined by maximally selected rank statistics.</p><p><strong>Results: </strong>SMG and SMD were independently associated with overall survival after adjustment for clinical and tumor characteristics. SMG and SMD demonstrated the highest prognostic accuracy (C-index 0.743 and 0.710, respectively). No linear relationship was observed between skeletal muscle metrics and BMI, underscoring the limitation of BMI in detecting sarcopenia. SMG values < 87,816 AU were associated with significantly worse survival in both sexes (HR 2.34, 95% CI 1.48-3.69; p < 0.001).</p><p><strong>Conclusions: </strong>SMG outperforms individual skeletal muscle indices in predicting overall survival following lung resection for early-stage NSCLC. These findings support the clinical utility of this composite measure for assessing cancer associated sarcopenia and advocate for the integration of automated body composition analysis into preoperative evaluation.</p>","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASO Visual Abstract: Longitudinal Academic Productivity of Complex General Surgical Oncology Fellowship Graduates: Misalignment between Training, Career Trajectory, and Workforce Needs.","authors":"Zachary A Whitham, Elaine Hu, Maria C Russell, Sean Dineen, Matthew R Porembka, Herbert J Zeh, Michael I D'Angelica, Adam C Yopp","doi":"10.1245/s10434-025-18505-0","DOIUrl":"https://doi.org/10.1245/s10434-025-18505-0","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145298270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}