Annals of Surgical Oncology最新文献

{"title":"ASO Visual Abstract: Outcomes of Neoadjuvant Chemotherapy versus Chemoradiation for Esophageal Adenocarcinoma: A National Cancer Database Analysis.","authors":"Ravi Shridhar, Jamie Huston, Kenneth Meredith","doi":"10.1245/s10434-025-18363-w","DOIUrl":"https://doi.org/10.1245/s10434-025-18363-w","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Technique and Feasibility of Pancreaticoduodenectomy after Surgery for Perihilar Cholangiocarcinoma.","authors":"Kota Sugiura, Atsushi Oba, Mamiko Miyashita, Hayato Baba, Ryota Ito, Gaku Shimane, Yui Sawa, Hiroyuki Shibata, Sho Kiritani, Kosuke Kobayashi, Yoshihiro Ono, Hiromichi Ito, Yosuke Inoue, Yu Takahashi","doi":"10.1245/s10434-025-18571-4","DOIUrl":"https://doi.org/10.1245/s10434-025-18571-4","url":null,"abstract":"<p><strong>Background: </strong>Standard treatment for perihilar cholangiocarcinoma (PHCC) involves major hepatectomy with caudate lobectomy and biliary-enteric reconstruction (Ann Surg. 258:129-140; Ann Surg Oncol. 29:6759-6771). Some patients may develop recurrence or second primary malignancies involving the intrapancreatic bile duct (J Am Coll Surg. 221:1041-1049; Surgery. 163:732-738). In selected cases, re-resection including pancreaticoduodenectomy (PD) may offer a valuable treatment option (Ann Surg. 262:121-129). However, reports of PD following prior PHCC surgery are extremely limited, and the technical aspects have not been systematically described (J Gastrointest Surg. 2015:19(12):2138-2145; J Med Case Rep. 2016:10(1):299).</p><p><strong>Methods: </strong>Between January 2012 and May 2025, five patients underwent PD after previous PHCC surgery. Operative videos and records were reviewed to assess characteristic technical elements, including adhesiolysis around the hepaticojejunostomy, mesenteric dissection with preservation of the jejunal limb blood supply, and complex reconstruction strategies. Postoperative outcomes were collected from medical records. Based on these data, we evaluated the technical feasibility of PD in this setting and proposed a classification of reconstruction patterns.</p><p><strong>Results: </strong>PD was successfully completed in all five cases. The median operative time was 463 minutes, and the median blood loss was 1155 mL. No complications of Clavien-Dindo grade III or higher occurred. The original hepaticojejunostomy was preserved in all cases. In four cases, the existing afferent limb was used for pancreaticojejunostomy (Child or Whipple type). In the remaining case, a new elevated jejunal limb was created for double-tract reconstruction.</p><p><strong>Conclusion: </strong>PD after prior PHCC surgery is technically feasible and can be safely performed. The proposed classification, along with the surgical video, may provide practical guidance for preoperative planning and intraoperative decision-making (see supplementary Figure 1).</p>","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluorescence Robot-Assisted Spleen-Preserving Distal Pancreatectomy (Warshaw Technique): A Spleen-Preserving Strategy with Intraoperative Confirmation of Splenic Perfusion (with Video).","authors":"Jianlin Lai, Zuwei Wang, Long Huang, Yifeng Tian, Shi Chen","doi":"10.1245/s10434-025-18536-7","DOIUrl":"https://doi.org/10.1245/s10434-025-18536-7","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival of Open Versus Thoracoscopic Esophagectomy for Esophageal Squamous Cell Cancer by Tumor Location: An Energy Balancing Weights Analysis.","authors":"Yishuo Gao, Yongli Yang, Tongtong Ren, Nana Wang, Peinan Chen, Funa Yang, Xiaocan Jia","doi":"10.1245/s10434-025-18562-5","DOIUrl":"https://doi.org/10.1245/s10434-025-18562-5","url":null,"abstract":"<p><strong>Background: </strong>The survival impact of open esophagectomy (OE) versus thoracoscopic esophagectomy (TE) in patients with esophageal squamous cell carcinoma (ESCC) based on tumor location remains debated. This study employs energy balancing weights (EBW) to compare long-term survival between OE and TE across tumor locations.</p><p><strong>Patients and methods: </strong>This ambispective cohort study analyzed 1778 patients with ESCC undergoing OE or TE at a tertiary hospital between January 2015 and December 2016. Primary endpoints were 5-year overall survival (OS) and disease-free survival (DFS); secondary endpoints included operative safety. EBW-adjusted Cox regression was used to compare long-term survival, with sensitivity analyses via inverse probability of treatment weighting and matching weight methods.</p><p><strong>Results: </strong>The median survival times for upper, middle, and lower tumor locations were 60.06, 60.48, and 64.35 months, respectively. Compared with OE, the Cox regression analysis of TE showed that in the upper group, the HR was 0.45 (95% CI 0.27-0.75) for OS and the HR was 0.55 (0.34-0.89) for DFS. In the middle group, theHR was 0.64 (0.48-0.85) for OS and the HR was 0.70 (0.53-0.91) for DFS. And in the lower group, the HR was 0.70 (0.44-1.11) for OS and the HR was 0.67 (0.43-1.04) for DFS. Additionally, TE was associated with reduced blood loss and increased lymph node yield but had longer operative times and higher costs (P < 0.05).</p><p><strong>Conclusions: </strong>TE improved survival and safety in upper/middle ESCC, while lower tumor locations require individualized approaches. EBW enhanced confounder control, supporting reliable clinical decisions.</p>","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Underutilization of Staging Laparoscopy Prior to Neoadjuvant Systemic Therapy in Gastric Cancer.","authors":"Arsha Ostowari, Kathryn T Chen, Bima J Hasjim, Stefania Montero, Shaina Sedighim, Fatemeh Tajik, Melanie Roman, Farshid Dayyani, Shaun Daly, Brian R Smith, Ninh T Nguyen, Oliver S Eng, Michael P O'Leary, Maheswari Senthil","doi":"10.1245/s10434-025-18547-4","DOIUrl":"https://doi.org/10.1245/s10434-025-18547-4","url":null,"abstract":"<p><strong>Background: </strong>Radiographically occult peritoneal carcinomatosis (PC) is a major concern in gastric cancer; hence staging laparoscopy (SL) is recommended prior to initiating treatment, particularly neoadjuvant systemic therapy (NST). However, compliance may vary and could result in understaging. We sought to evaluate the utilization of SL in patients with gastric cancer referred to academic institutions.</p><p><strong>Patients and methods: </strong>This is a multi-institution retrospective study of patients with a diagnosis of gastric/gastroesophageal junction (GEJ) Siewert 3 adenocarcinoma who received treatment between 2010 and 2022. Demographics, tumor characteristics, treatment, and recurrence data were collected. Descriptive statistics and multivariate analysis were performed.</p><p><strong>Results: </strong>A total of 280 patients with gastric/GEJ cancer were identified, of which 75 (26.8%) had clinical stage IV disease and were excluded. Of the remaining 205 patients, 74 (36.1%) underwent upfront surgery and 131 (63.1%) underwent NST. Only 39 (29.8%) patients in the NST group underwent SL, of whom 15(38.4%) were found to have peritoneal metastases; 12 (80%) had gross PC and 3 (20%) had positive cytology. Among patients who underwent surgical resection after NST (n = 77), 26 (33.7%) experienced disease recurrence with a median time to recurrence of 11.6 months. The peritoneum (n = 10/26, 38.5%) was the most common site of recurrence.</p><p><strong>Conclusions: </strong>Compliance with SL prior to NST is poor (29.8%), and in the group that underwent SL, 38% of patients were upstaged due to presence of peritoneal metastases. These findings are significant, as the management and prognosis of peritoneal metastases are drastically different. Various factors could lead to poor compliance with SL, hence better compliance and alternate approaches to reliably detect PC are needed.</p>","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145312113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASO Visual Abstract: Survival Benefit of Adjuvant S-1 Chemotherapy in Patients Aged ≥ 80 Years with Gastric Cancer after Curative Resection-A Multicenter Cohort Study.","authors":"Shutaro Sumiyoshi, Takeshi Kubota, Hiroyuki Inoue, Kazuya Takabatake, Keiji Nishibeppu, Junichi Hamada, Toshiya Ochiai, Yosuke Ariyoshi, Atsushi Toma, Kenji Watanabe, Nobuki Yamaoka, Soujin Sai, Shozo Ide, Tomoya Hatakeyama, Yoshiki Itokawa, Fumiaki Ochi, Hirotaka Konishi, Hitoshi Fujiwara, Miho Sekimoto, Satoru Shikata, Atsushi Shiozaki","doi":"10.1245/s10434-025-18577-y","DOIUrl":"https://doi.org/10.1245/s10434-025-18577-y","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145306929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASO Author Reflections: Robotic Segmental Hepatic Resection Associated to Pancreatoduodenectomy for Gallbladder Cancer and Extrahepatic Cholangiocarcinoma.","authors":"Guanyu Wang, Zhuzeng Yin","doi":"10.1245/s10434-025-18565-2","DOIUrl":"https://doi.org/10.1245/s10434-025-18565-2","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145312177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASO Author Reflections: Improving Preoperative Risk Stratification for Esophagectomy: Insights from Cardiopulmonary Exercise Testing.","authors":"Watson Hua-Sheng Tseng, Shu-Chun Huang","doi":"10.1245/s10434-025-18564-3","DOIUrl":"https://doi.org/10.1245/s10434-025-18564-3","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145306928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASO Author Reflections: The Survival for Pneumonectomy After Neoadjuvant Therapy in Non-Small Cell Lung Cancer.","authors":"Sikai Wu, Xiaowei Chen, Ershu Bo, Haixiao Diao, Zhenlin Yang, Shugeng Gao","doi":"10.1245/s10434-025-18576-z","DOIUrl":"https://doi.org/10.1245/s10434-025-18576-z","url":null,"abstract":"","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145312128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally Invasive Gastrectomy for Borrmann Type IV Gastric Cancer: An Oncologically Sound Alternative to Open Surgery.","authors":"Jawon Hwang, Ki-Yoon Kim, Sung Hyun Park, Minah Cho, Yoo Min Kim, Hyoung-Il Kim, Woo Jin Hyung","doi":"10.1245/s10434-025-18573-2","DOIUrl":"https://doi.org/10.1245/s10434-025-18573-2","url":null,"abstract":"<p><strong>Background: </strong>Previous studies have validated the oncologic safety of minimally invasive surgery (MIS) for advanced gastric cancer, but the feasibility of applying MIS to treat Borrmann type IV gastric cancer remains unclear. Given its distinct clinicopathological features, poor prognosis, and technical complexities in surgery, further investigation is needed. This study aimed to compare the surgical and oncological outcomes between open surgery and MIS in patients with Borrmann type IV gastric cancer.</p><p><strong>Methods: </strong>We retrospectively analyzed data from 1025 patients who underwent open (n = 888) or minimally invasive (n = 137) gastrectomy for Borrmann type IV gastric cancer between 2003 and 2021. Propensity score matching was performed to balance baseline characteristics, and short- and long-term outcomes were compared between the matched groups.</p><p><strong>Results: </strong>After propensity score matching, each group included 112 matched patients. The MIS group had longer operative times (p < 0.001) but shorter hospital stays (p < 0.001) than the open surgery group. Other perioperative outcomes showed no significant differences. Overall and recurrence-free survival were comparable between the two groups (p = 0.741 and p = 0.707, respectively). Adjusted hazard ratios for death and recurrence following MIS compared with open surgery were 1.20 (95% confidence interval 0.78-1.85, p = 0.396) and 1.22 (95% confidence interval 0.83-1.79, p = 0.308), respectively.</p><p><strong>Conclusion: </strong>Our findings suggest that MIS for Borrmann type IV gastric cancer may offer long-term oncologic outcomes comparable to those with open surgery while preserving the inherent benefits of MIS.</p>","PeriodicalId":8229,"journal":{"name":"Annals of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145306877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}