News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society最新文献

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Forces, fishes, and fluids: hydrodynamic mechanisms of aquatic locomotion. 力、鱼和流体:水生运动的水动力机制。
George V Lauder, Eliot G Drucker
{"title":"Forces, fishes, and fluids: hydrodynamic mechanisms of aquatic locomotion.","authors":"George V Lauder,&nbsp;Eliot G Drucker","doi":"10.1152/nips.01398.2002","DOIUrl":"https://doi.org/10.1152/nips.01398.2002","url":null,"abstract":"<p><p>Understanding how fishes generate external fluid force to swim steadily and maneuver has proven to be difficult because water does not provide a stable platform for force measurement. But new methods in experimental fluid mechanics provide insights into the physiological mechanisms of aquatic force generation and limits to locomotor performance.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"17 ","pages":"235-40"},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01398.2002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22113982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 127
The physiological and evolutionary significance of cardiovascular shunting patterns in reptiles. 爬行动物心血管分流模式的生理和进化意义。
James W Hicks
{"title":"The physiological and evolutionary significance of cardiovascular shunting patterns in reptiles.","authors":"James W Hicks","doi":"10.1152/nips.01397.2002","DOIUrl":"https://doi.org/10.1152/nips.01397.2002","url":null,"abstract":"<p><p>The morphology of the reptilian heart results in the mixing of oxygenated and deoxygenated blood (cardiac shunts). In birds and mammals cardiac shunts are detrimental, but in reptiles this condition is often considered a derived trait, conveying important physiological functions and favored by natural selection. Alternative views are advanced suggesting that, in reptiles, cardiac shunts represent either an ancestral condition or an embryonic trait.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"17 ","pages":"241-5"},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01397.2002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22113983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 84
Fusion pore in live cells. 活细胞中的融合孔。
Bhanu P Jena
{"title":"Fusion pore in live cells.","authors":"Bhanu P Jena","doi":"10.1152/nips.01394.2002","DOIUrl":"https://doi.org/10.1152/nips.01394.2002","url":null,"abstract":"<p><p>Earlier electrophysiological measurements on live secretory cells suggested the presence of fusion pores at the plasma membrane, where secretory vesicles fuse to release vesicular contents. Recent studies using atomic force microscopy demonstrate for the first time the presence of the fusion pore and reveal its morphology and dynamics at near-nanometer resolution and in real time.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"17 ","pages":"219-22"},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22114082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Spatial heterogeneity in the heart: recent insights and open questions. 心脏的空间异质性:最近的见解和悬而未决的问题。
Ulrich K M Decking
{"title":"Spatial heterogeneity in the heart: recent insights and open questions.","authors":"Ulrich K M Decking","doi":"10.1152/nips.01393.2002","DOIUrl":"https://doi.org/10.1152/nips.01393.2002","url":null,"abstract":"<p><p>Within the left ventricular myocardium and despite its rather homogeneous structure, local myocardial perfusion varies substantially. Areas of low and high local flow differ with regard to substrate uptake, energy turnover, and demand. This spatial heterogeneity is related to distinct differences in local protein expression, forming the basis of a novel homeostatic mechanism.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"17 ","pages":"246-50"},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01393.2002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22113984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
Indexes of NO bioavailability in human blood. NO在人血液中的生物利用度指标。
Thomas Lauer, Petra Kleinbongard, Malte Kelm
{"title":"Indexes of NO bioavailability in human blood.","authors":"Thomas Lauer,&nbsp;Petra Kleinbongard,&nbsp;Malte Kelm","doi":"10.1152/nips.01405.2002","DOIUrl":"https://doi.org/10.1152/nips.01405.2002","url":null,"abstract":"<p><p>Disturbances of nitric oxide (NO) bioavailability may play a key role in vascular dysfunction and in the development of atherosclerotic lesions. Thus assessment of a reduced NO bioavailability in human circulation is of particular interest. Here we summarize potential biomarkers of NO availability in human blood and critically discuss their respective significance and application fields.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"17 ","pages":"251-5"},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01405.2002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22113985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 65
Pulmonary edema and elevated left atrial pressure: four hours and beyond. 肺水肿和左房压升高:4小时及以上。
R E Drake, M F Doursout
{"title":"Pulmonary edema and elevated left atrial pressure: four hours and beyond.","authors":"R E Drake,&nbsp;M F Doursout","doi":"10.1152/nips.01399.2002","DOIUrl":"https://doi.org/10.1152/nips.01399.2002","url":null,"abstract":"<p><p>Cardiogenic pulmonary edema is caused by the increase in left atrial pressure when the left heart fails. The increased pressure causes rapid fluid accumulation within the lung interstitial spaces. However, over the following days to weeks, additional fluid may accumulate due to the deposition of excess lung connective tissue.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"17 ","pages":"223-6"},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01399.2002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22114083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Cerebrospinal fluid transport: a lymphatic perspective. 脑脊液运输:淋巴的视角。
M Johnston, C Papaiconomou
{"title":"Cerebrospinal fluid transport: a lymphatic perspective.","authors":"M Johnston,&nbsp;C Papaiconomou","doi":"10.1152/nips.01400.2002","DOIUrl":"https://doi.org/10.1152/nips.01400.2002","url":null,"abstract":"<p><p>The textbook view that projections of the arachnoid membrane into the cranial venous sinuses represent the primary cerebrospinal fluid (CSF) absorption sites seems incompatible with many clinical and experimental observations. On balance, there is more quantitative evidence suggesting a function for extracranial lymphatic vessels than exists to support a role for arachnoid villi and granulations in CSF transport.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"17 ","pages":"227-30"},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01400.2002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22114084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 102
It takes "heart" to win: what makes the heart powerful? 赢得胜利需要“心”:是什么让心变得强大?
Kerry S McDonald, Todd J Herron
{"title":"It takes \"heart\" to win: what makes the heart powerful?","authors":"Kerry S McDonald,&nbsp;Todd J Herron","doi":"10.1152/nips.01396.2002","DOIUrl":"https://doi.org/10.1152/nips.01396.2002","url":null,"abstract":"<p><p>The pumping action of the heart varies considerably on a beat-to-beat basis and is ultimately determined by the extent of ventricular myocyte shortening during systole. The use of isolated myocardial preparations has provided new insights about the subcellular factors that modulate power output of the ventricles.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"17 ","pages":"185-90"},"PeriodicalIF":0.0,"publicationDate":"2002-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01396.2002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22009192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Metabolic myopathy in heart failure. 心力衰竭的代谢性肌病。
Renée Ventura-Clapier, Elvira De Sousa, Vladimir Veksler
{"title":"Metabolic myopathy in heart failure.","authors":"Renée Ventura-Clapier,&nbsp;Elvira De Sousa,&nbsp;Vladimir Veksler","doi":"10.1152/nips.01392.2002","DOIUrl":"https://doi.org/10.1152/nips.01392.2002","url":null,"abstract":"<p><p>Heart failure is a syndrome that also affects the periphery. Exercise intolerance and early fatigue seem to be linked in part to intrinsic alterations of skeletal muscle with decreases in both the production of ATP by mitochondria and the transfer of energy through the phosphotransfer kinases.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"17 ","pages":"191-6"},"PeriodicalIF":0.0,"publicationDate":"2002-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01392.2002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22009193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 62
William Harvey and the circulation of the blood: the birth of a scientific revolution and modern physiology. 威廉·哈维和血液循环:科学革命和现代生理学的诞生。
Stanley G Schultz
{"title":"William Harvey and the circulation of the blood: the birth of a scientific revolution and modern physiology.","authors":"Stanley G Schultz","doi":"10.1152/nips.01391.2002","DOIUrl":"https://doi.org/10.1152/nips.01391.2002","url":null,"abstract":"","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"17 ","pages":"175-80"},"PeriodicalIF":0.0,"publicationDate":"2002-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01391.2002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22009190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 38
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