Archives of Dermatological Research最新文献_第9页

Patients with head and neck invasive melanoma have nearly 1:4 risk of separate lifetime primary melanoma. 头颈部浸润性黑色素瘤患者终生单独患原发性黑色素瘤的风险接近 1:4。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-08-24 DOI: 10.1007/s00403-024-03311-7

Elliott Campbell, Thomas Trischman, Anagha Bangalore Kumar, Eucabeth Asamoah, Nahid Vidal, Addison Demer

引用次数: 0

Disproportionality analysis of psychiatric morbidities associated with isotretinoin using VigiBase. 使用 VigiBase 对与异维A酸相关的精神病发病率进行比例分析。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-08-24 DOI: 10.1007/s00403-024-03293-6

Eric Xia, Priya Manjaly, Sophia Ly, Kanika Kamal, Nicholas Theodosakis, Arash Mostaghimi

引用次数: 0

The interplay between neural and immune responses as a key concept in AD development. 神经和免疫反应之间的相互作用是注意力缺失症发展过程中的一个关键概念。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-08-24 DOI: 10.1007/s00403-024-03333-1

Anna Keshishyan, Khachik Khachikyan

引用次数: 0

Clinical efficacy of 595 nm pulsed dye laser in combination with supramolecular salicylic acid in the treatment of rosacea. 595 nm 脉冲染料激光联合超分子水杨酸治疗红斑痤疮的临床疗效。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-08-24 DOI: 10.1007/s00403-024-03290-9

Wei Lei, Huang Chen, Liuqing Chen, Meng Li, Jun Zhang, Xuegang Xu

{"title":"Clinical efficacy of 595 nm pulsed dye laser in combination with supramolecular salicylic acid in the treatment of rosacea.","authors":"Wei Lei, Huang Chen, Liuqing Chen, Meng Li, Jun Zhang, Xuegang Xu","doi":"10.1007/s00403-024-03290-9","DOIUrl":"https://doi.org/10.1007/s00403-024-03290-9","url":null,"abstract":"Objective: This research was aimed at ascertaining the clinical effects of 595 nm pulsed dye laser (PDL) in combination with supramolecular salicylic acid (SSA) in the treatment of rosacea.Methods: Eighty-four patients with rosacea were selected, of which 42 patients treated with PDL alone were considered as the control group, and 42 patients treated with 595 nm PDL in combination with 30% SSA were regarded as the observation group. The treatment continued for 4 months in the two groups. Clinical symptom scores, skin barrier function indicators, serum inflammatory factors, Acne⁃QOL scores and adverse reactions between the two groups were compared.Results: After treatment, levels of inflammatory factors, clinical symptom scores, transdermal water loss, and oil volume were decreased, and epidermal water content and Acne-QOL scores were increased in both groups (all P < 0.05), and the changes in the observation group were more pronounced versus the control group (all P < 0.05). The difference in the incidence of adverse reactions was not statistically significant between the two groups (P > 0.05).Conclusion: 595 nm PDL in combination with SSA is safe in the treatment of rosacea.","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving hidradenitis suppurativa management: consensus statements from physicians and patients' perspectives. 改善化脓性扁桃体炎的管理：医生和患者观点的共识声明。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-08-24 DOI: 10.1007/s00403-024-03316-2

Angelo Valerio Marzano, Cristina Magnoni, Giuseppe Micali, Angelina De Magnis, Giuseppina Pintori, Simone Fiorini, Valentina Simonella, Linda Bastioli, Francesca Nappi, Giovanni Pappagallo, Francesca Prignano

{"title":"Improving hidradenitis suppurativa management: consensus statements from physicians and patients' perspectives.","authors":"Angelo Valerio Marzano, Cristina Magnoni, Giuseppe Micali, Angelina De Magnis, Giuseppina Pintori, Simone Fiorini, Valentina Simonella, Linda Bastioli, Francesca Nappi, Giovanni Pappagallo, Francesca Prignano","doi":"10.1007/s00403-024-03316-2","DOIUrl":"10.1007/s00403-024-03316-2","url":null,"abstract":"Hidradenitis suppurativa (HS) is a frequent chronic inflammatory skin condition primarily affecting areas rich in apocrine sweat glands, presenting with comedones, papules, nodules, and abscesses, as well as tunnels and hypertrophic scarring. Despite its prevalence and impact on quality of life, the pathogenesis of HS remains incompletely understood. Notably, its diagnosis often suffers from delays and misidentification, therefore an improved education for healthcare providers is mandatory. Moreover, HS is frequently associated with systemic comorbidities and a multidisciplinary approach is suggested for its management. Recognizing these challenges, a group of Italian HS experts and patients convened to develop consensus guidelines via the Nominal Group Technique. Through iterative meetings and remote collaboration, they identified key areas for improvement and formulated consensus statements to guide healthcare providers in delivering optimal care. This collaborative effort highlights the importance of standardized approaches and interdisciplinary collaboration in managing HS effectively.","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11344722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of COVID-19 pandemic upon the infectious skin diseases observed among healthcare providers. COVID-19 大流行对医护人员传染性皮肤病的影响。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-08-24 DOI: 10.1007/s00403-024-03335-z

Ecem Bostan, Mahmut Talha Uçar

引用次数: 0

The treatment of Tofacitinib for rosacea through the inhibition of the JAK/STAT signaling pathway. 托法替尼通过抑制 JAK/STAT 信号通路治疗酒渣鼻。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-08-24 DOI: 10.1007/s00403-024-03314-4

Rui Sun, Huiping Fan, Jiayun Liu, Guomin Gao, Chengqi Liu, Dong Zhang, Weiyuan Ma

{"title":"The treatment of Tofacitinib for rosacea through the inhibition of the JAK/STAT signaling pathway.","authors":"Rui Sun, Huiping Fan, Jiayun Liu, Guomin Gao, Chengqi Liu, Dong Zhang, Weiyuan Ma","doi":"10.1007/s00403-024-03314-4","DOIUrl":"10.1007/s00403-024-03314-4","url":null,"abstract":"Rosacea is a chronic inflammatory skin disease characterized by facial erythema and telangiectasia. Despite ongoing research, the pathogenesis of rosacea remains incompletely understood, and current therapies are not entirely satisfactory. The JAK/STAT signaling pathway plays an essential role in immunoregulation, inflammation, and neurovascular regulation. Inhibition of the JAK/STAT pathway appears to hold promise as a potential therapy for rosacea. This study aimed to investigate the effects of the JAK inhibitor tofacitinib on rosacea and to preliminarily explore its therapeutic mechanism. To this end, a rosacea-like mouse model was induced using LL37 and treated with a 2% tofacitinib emulsion. The results demonstrated that topical application of tofacitinib significantly ameliorated rosacea-like phenotype, reduced the infiltration of CD4+ T cells and mast cells, and suppressed dermal angiogenesis. RT-qPCR analysis revealed a reduction in mRNA expression levels of STAT1, STAT4, and STAT5a in skin lesions following topical tofacitinib treatment. Additionally, three patients diagnosed with erythematotelangiectatic rosacea (ETR) were included in the study and treated with oral tofacitinib, leading to a significant improvement in erythema and flushing symptoms. These findings collectively suggest that tofacitinib alleviates LL37-induced rosacea-like skin inflammation in mice and rosacea skin lesions by inhibiting the JAK/STAT signaling pathway.","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Strategies for improving dermatologist comfort and quality of patient care in inpatient settings: a cross-sectional survey study. 提高皮肤科医生舒适度和住院患者护理质量的策略：横断面调查研究。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-08-24 DOI: 10.1007/s00403-024-03329-x

Charles B Lau, Gideon P Smith

引用次数: 0

Beyond the shell: malacology in medical dermatology. 超越外壳：医学皮肤病学中的孔雀石学。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-08-24 DOI: 10.1007/s00403-024-03343-z

Max Oscherwitz, Brandon M Godinich, Nupur Singh, Bethany R Rohr

引用次数: 0

Alopecia areata is associated with lichen planus and lichen sclerosus in a case-control study of 4,785 patients. 在一项对 4,785 名患者进行的病例对照研究中，斑秃与扁平苔藓和硬皮病有关。

IF 1.8 4区医学

Archives of Dermatological Research Pub Date : 2024-08-24 DOI: 10.1007/s00403-024-03270-z

Kaya L Curtis, Onajia Stubblefield, Brieann H Sobieski, Shari R Lipner

引用次数: 0