Archives of Academic Emergency Medicine最新文献

{"title":"Public Comments on social media Regarding Self-management of Foreign Body Airway Obstruction; a Letter to Editor.","authors":"Alexei A Birkun","doi":"10.22037/aaem.v12i1.2489","DOIUrl":"https://doi.org/10.22037/aaem.v12i1.2489","url":null,"abstract":"<p><p>Foreign body airway obstruction (FBAO) frequently occurs unwitnessed. In the absence of external assistance and the ability to rapidly reach help, immediate self-management of FBAO could be the only way to avoid impending death from asphyxia. In this letter, relevant evidence of real-life self-management of severe FBAO from public comments posted on social media were gathered and reported. The results indicate that in cases of severe FBAO, laypeople apply self-management maneuvers notwithstanding that self-help is omitted from the current resuscitation guidelines.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"12 1","pages":"e68"},"PeriodicalIF":2.9,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11407530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stem Cell-Derived Exosomes as a Therapeutic Option for Spinal Cord Injuries; a Systematic Review and Meta-Analysis.","authors":"Sajjad Jabermoradi, Parsa Paridari, Hamzah Adel Ramawad, Pantea Gharin, Shayan Roshdi, Amirmohammad Toloui, Mahmoud Yousefifard","doi":"10.22037/aaem.v12i1.2261","DOIUrl":"10.22037/aaem.v12i1.2261","url":null,"abstract":"<p><strong>Introduction: </strong>Exosomes function as cell signaling carriers and have drawn much attention to the cell-free treatments of regenerative medicine. This meta-analysis aimed to investigate the efficacy of mesenchymal stem cell-derived (MSC-derived) exosomes in animal models of spinal cord injuries (SCI).</p><p><strong>Method: </strong>A comprehensive search was conducted in Medline, Embase, Scopus, and Web of Science to attain related articles published by January 31, 2023. The eligible keywords were correlated with the spinal cord injury and MSC-derived exosomes. The evaluated outcomes were locomotion, cavity size, cell apoptosis, inflammation, neuro-regeneration, and microglia activation. A standardized mean difference was calculated for each sample and a pooled effect size was reported.</p><p><strong>Results: </strong>65 papers fully met the inclusion criteria. Treatment with MSC-derived exosomes ultimately improved locomotion and shrunk cavity size (p<0.0001). The administration of MSC-derived exosomes enhanced the expression of beta-tubulin III, NF200, and GAP-43, and increased the number of NeuN-positive and Nissl-positive cells, while reducing the expression of glial fibrillary acidic protein (p<0.0001). The number of apoptotic cells in the treatment group decreased significantly (p<0.0001). Regarding the markers of microglia activation, MSC-derived exosomes increased the number of CD206- and CD68-positive cells (p=0.032 and p<0.0001, respectively). Additionally, MSC-derived exosome administration significantly increased the expression of the anti-inflammatory interleukin (IL)-10 and IL-4 (p<0.001 and p=0.001, respectively) and decreased the expression of the inflammatory IL-1b, IL-6, and TNF-a (p<0.0001).</p><p><strong>Conclusion: </strong>MSC-derived exosome treatment resulted in a significantly improved locomotion of SCI animals through ameliorating neuroinflammation, reducing apoptosis, and inducing neuronal regrowth by facilitating a desirable microenvironment.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"13 1","pages":"e2"},"PeriodicalIF":2.9,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitudes, and Perceived Barriers of Nurses Regarding Pain Management in Emergency Department; a KAP Study.","authors":"Farzad Bozorgi, Morteza Ghorbani Afrachali, Shiv Kumar Mudgal, Zohreh Hosseini Marznaki, Iraj Goli Khatir, Nipin Kalal, Fatemeh Keshavarzi, Seyed Mohammad Hosseininejad","doi":"10.22037/aaem.v12i1.2356","DOIUrl":"https://doi.org/10.22037/aaem.v12i1.2356","url":null,"abstract":"<p><strong>Introduction: </strong>Adequate knowledge and positive attitude among nurses are essential for successful pain management as a fundamental aspect of patients' rights. This study aimed to assess the knowledge, attitude and perceived barriers of nurses regarding acute pain management in emergency department.</p><p><strong>Methods: </strong>In this cross-sectional study, participating nurses were selected using a consecutive sampling technique within a medical university. Data were collected using 4 questionnaires, which consisted of demographic information checklist, Pain Management Principles Assessment Tool (PMPAT), Nurses' Attitude Survey (NAS), and Nurses' practice checklist. The correlation between knowledge, attitude, and barriers with each other and with baseline characteristics of participates were studied.</p><p><strong>Results: </strong>400 nurses with the mean age of 38.26±10.39 years were studied (63% male). The average knowledge score of studied nurses was 7.38 ± 2.16 (range: 1 -14). All 400 (100%) nurses exhibited a low level of knowledge. The mean attitude score of participants was 58.47± 22.08 (range:26-100). 214 (53.5%) cases had low attitude, 44 (11.0 %) average attitude, and 142 (35.5%) cases exhibited a high attitude score. The mean score of barriers about pain management was 36.48 ± 23.52 (range: 0 - 80). 23 (5.8%) participants answered the perceived barriers as never, 113 (28.3%) as seldom, 71 (17.8%) as sometimes, 133 (33.3%) as often, and 60 (15.0%) as routine. There was an reverse relationship between the knowledge score and perceived barriers of pain management (r=-0.164, p<0.001). No significant relationship was found between the average knowledge score and nurses' attitudes (r = 0.092; p > 0.065).</p><p><strong>Conclusions: </strong>The findings of this study highlight the need for ongoing training and the organization of workshops for nurses due to their low levels of knowledge and attitude. These training sessions should focus on the concept of pain, assessment methods, pain relief, as well as pharmacology and the physiology of pain.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"12 1","pages":"e67"},"PeriodicalIF":2.9,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11407532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Administration of Apelin Could Prevent Heart Failure Following Myocardial Injury; A Systematic Review and Meta-Analysis.","authors":"Mohammad-Mehdi Hasheminezhad, Mina Mirzad","doi":"10.22037/aaem.v13i1.2414","DOIUrl":"https://doi.org/10.22037/aaem.v13i1.2414","url":null,"abstract":"<p><strong>Introduction: </strong>Heart failure (HF) is a prevalent and advancing cardiovascular disorder that impacts 1-2% of the worldwide population, particularly the elderly. Studies indicate that the intravenous administration of apelin may yield advantageous effects in preventing heart failure subsequent to myocardial injury. This meta-analysis aimed to assess the effects of exogenous apelin administration on heart failure in animal models, in light of the lack of a definitive consensus on the matter.</p><p><strong>Method: </strong>An extensive search was performed in the Medline (via PubMed), Web of Science, Embase, and Scopus databases till the end of January 2024. Two independent reviewers screened and summarized the relevant articles. Outcomes related to cardiac function, including ejection fraction (EF), maximum and minimum rate of left ventricle systolic pressure (+dp/dt and -dp/dt, respectively), heart rate, left ventricular end-diastolic pressure (LVEDP), and left ventricular systolic pressure (LVSP) were assessed. Findings were reported as a pooled standardized mean difference (SMD) with a 95% confidence interval (95% CI).</p><p><strong>Results: </strong>12 studies were included. Pooled analysis demonstrated that early treatment with apelin following myocardial injury significantly increases +dp/dt (SMD = 2.36; 95% CI: 1.58 to 3.15; p < 0.001) and decreases -dp/dt (SMD = -3.31; 95% CI: -4.46 to -2.17; p < 0.001). Furthermore, the administration of apelin resulted in a significant increase in EF (SMD = 0.79; 95% CI: 0.15 to 1.44; p = 0.02) and LVSP (SMD = 2.09; 95% CI: 0.82 to 3.36; p < 0.001), while it led to a decrease in LVEDP in the animals (SMD = -1.85; 95% CI: -2.81 to -0.88; p < 0.001). Noteworthy, apelin treatment was shown to have no significant influence on the heart rate of the animals (SMD = -0.12; 95% CI: -0.82 to -0.58; p = 0.73).</p><p><strong>Conclusion: </strong>The current study demonstrated that the early administration of apelin has the potential to improve cardiac function and mitigate the onset of heart failure subsequent to myocardial injury. Further, in vivo research is essential to lay the groundwork for the integration of apelin into clinical practice.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"13 1","pages":"e4"},"PeriodicalIF":2.9,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Value of Chest Computed Tomography Scan for Identification of Foreign Body Aspiration in Children: A Systematic Review and Meta-analysis.","authors":"Babak Goodarzy, Erfan Rahmani, Mehrdad Farrokhi, Reza Tavakoli, Atousa Moghadam Fard, Mohadese Ranjbaran Ghaleh, Yeganeh Ghalichebaf Yazdi, Reza Amani Beni, Erfan Ghadirzadeh, Fatemeh Afrazeh, Yalda Alipour Khabir, Sevda Alipour Khabir, Paria Bakhtiyari, Javaneh Atighi, Mohammad Mahjoubi, Zahra Momeni, Hediyeh Jalayeri, Mohammad Hossein Hosseini, Behnam Hoorshad, Mehdi Tavakoli, Sepideh Seifi, Hamidreza Momeni, Amirhossein Mirbolook, Alireza Esmaili Jobani, Mozhdeh Mohammadi Visroud, Aboulfazl Najafi, Zahrasadat Hosseini, Sobhan Aboulhassanzadeh, Negar Ajami, Sahel Ramezani, Mahdokht Sadat Manavi, Sina Safdari, Amirali Fallahian, Habib Azimi, Reza Zahedpasha, Ehsan Ranjbar, Mohammad Saeed Kahrizi, Lida Zare Lahijan","doi":"10.22037/aaem.v12i1.2431","DOIUrl":"10.22037/aaem.v12i1.2431","url":null,"abstract":"<p><strong>Introduction: </strong>Foreign body aspiration (FBA) is a common, life-threatening pediatric emergency and was shown to be associated with high risk of morbidity and mortality. This systematic review and meta-analysis aimed to investigate the diagnostic value of chest computed tomography (CT) scan for identification of FBA in children.</p><p><strong>Methods: </strong>From inception to May 2024, a systematic search was carried out across multiple databases including Medline, Scopus, and Web of Science, considering published papers in English language. Quality assessment of the included studies was performed using seven domains of Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2).</p><p><strong>Results: </strong>The systematic literature search yielded 7203 articles. The pooled sensitivity and specificity of chest CT scan for identification of FBA were 0.99 (95% CI: 0.98-0.99) and 0.97 (95% CI: 0.96-0.98), respectively. The pooled positive likelihood ratio was 10.12 (95% CI: 4.59-22.20), and pooled negative likelihood ratio was 0.05 (95% CI: 0.02-0.1). Furthermore, the area under the summarized receiver operating characteristic (SROC) curve was 0.98.</p><p><strong>Conclusion: </strong>Our meta-analysis revealed that despite high heterogeneity, in the diagnostic characteristics of chest CT scan among studies, it has high diagnostic value in identifying FBA in suspected pediatric cases.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"13 1","pages":"e3"},"PeriodicalIF":2.9,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Basic Reproduction Number (R0), Doubling Time, and Daily Growth Rate of the COVID-19 Epidemic: An Echological Study.","authors":"Roya Karimi, Mehrdad Farrokhi, Neda Izadi, Hadis Ghajari, Fatemeh Khosravi Shadmani, Farid Najafi, Ebrahim Shakiba, Manoochehr Karami, Masoud Shojaeian, Ghobad Moradi, Ebrahim Ghaderi, Elham Nouri, Ali Ahmadi, Abdollah Mohammadian Hafshejani, Majid Sartipi, Alireza Zali, Ayad Bahadori Monfared, Raha Davatgar, Seyed Saeed Hashemi Nazari","doi":"10.22037/aaem.v12i1.2376","DOIUrl":"https://doi.org/10.22037/aaem.v12i1.2376","url":null,"abstract":"<p><strong>Introduction: </strong>In infectious diseases, there are essential indices used to describe the disease state. In this study, we estimated the basic reproduction number, R0, peak level, doubling time, and daily growth rate of COVID-19.</p><p><strong>Methods: </strong>This ecological study was conducted in 5 provinces of Iran. The daily numbers of new COVID-19 cases from January 17 to February 8, 2020 were used to determine the basic reproduction number (R0), peak date, doubling time, and daily growth rates in all five provinces. A sensitivity analysis was conducted to estimate epidemiological parameters.</p><p><strong>Result: </strong>The highest and lowest number of deaths were observed in Hamedan (657 deaths) and Chaharmahal and Bakhtiari (54 deaths) provinces, respectively. The doubling time of confirmed cases in Kermanshah and Hamedan ranged widely from 18.59 days (95% confidence interval (CI): 17.38, 20) to 76.66 days (95% CI: 56.36, 119.78). In addition, the highest daily growth rates of confirmed cases were observed in Kermanshah (0.037, 95% CI: 0.034, 0.039) and Sistan and Baluchestan (0.032, 95% CI: 0.030, 0.034) provinces.</p><p><strong>Conclusion: </strong>In light of our findings, it is imperative to tailor containment strategies to the unique epidemiological profiles of each region in order to effectively mitigate the spread and impact of COVID-19. The wide variation in doubling times underscores the importance of flexibility in public health responses. By adapting measures to local conditions, we can better address the evolving dynamics of the pandemic and safeguard the well-being of communities.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"12 1","pages":"e66"},"PeriodicalIF":2.9,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11407535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Video Laryngoscope (VL) and Intubating Laryngeal Mask Airway (I-LMA) for Endotracheal Intubation in a Manikin with Restricted Neck Motion.","authors":"Welawat Tienpratarn, Methapat Boonyingsatit, Chaiyaporn Yuksen, Sittichok Leela-Amornsin, Parunchaya Jamkrajang, Thammanunt Chrunarm, Sumate Rienrakwong","doi":"10.22037/aaem.v12i1.2421","DOIUrl":"10.22037/aaem.v12i1.2421","url":null,"abstract":"<p><strong>Introduction: </strong>Intubating patients undergoing manual in-line stabilization (MILS) can make airway management more challenging. This study aimed to compare the outcomes of intubation with video-laryngoscope (VL) and Intubating Laryngeal Mask Airway (I-LMA) in manikin with restricted neck motion using MILS.</p><p><strong>Methods: </strong>In this comparative study, emergency medicine residents and paramedics were randomly allocated to two crossover sets. Then the intubation outcomes (success rate, time to successful intubation, and cervical spine movement) were compared between intubation with VL and I-LMA in a manikin model with restricted cervical spine mobility, achieved through MILS.</p><p><strong>Results: </strong>64 participants with a mean age of 28.86 ± 4.03 (range: 24-47) years and a mean duration of intubation experience of 3.63 ± 1.35 years were studied (43.75% male, 81.3% emergency medicine resident). The intubation success rate was 62 out of 64 (96.88%) in the VL method and 52 out of 64 (81.25%) in the I-LMA method (p = 0.008). The mean time to successful intubation was 33.03±16.94 seconds in the VL method and 55.03±17.34 seconds in the I-LMA method (p < 0.001). The mean cervical range of motion (CROM) in flexion-extension was 4.38±1.82 degrees in the VL method and 4.13±3.20 degrees in the I-LMA method (p = 0.158). The mean CROM in rotation was 4.27±2.62 degrees in the VL method and 4.65±2.47 degrees in the I-LMA method (p= 0.258) and the mean CROM in lateral bending was 5.35±4.45 degrees in the VL method and 7.71±6.14 degrees in the I-LMA method (p = 0.010).</p><p><strong>Conclusion: </strong>In a manikin model with restricted cervical spine mobility, the utilization of VL significantly improved intubation success rates, reduced time to successful intubation, and limited CROM.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"13 1","pages":"e1"},"PeriodicalIF":2.9,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Piperonylbutoxide and the Necessity of Toxicological Assessment of Insecticide Mixtures; a Letter to Editor.","authors":"Dirk Habedank, Birgit Habedank","doi":"10.22037/aaem.v12i1.2434","DOIUrl":"https://doi.org/10.22037/aaem.v12i1.2434","url":null,"abstract":"","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"12 1","pages":"e64"},"PeriodicalIF":2.9,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11407539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Guide to Opportunities and Challenges of Developing a Virtual Reality Simulation for Disaster Medicine Courses: A Letter to Editor.","authors":"Mohsen Masoumian Hosseini, Seyedeh Toktam Masoumian Hosseini, Karim Qayumi","doi":"10.22037/aaem.v12i1.2388","DOIUrl":"https://doi.org/10.22037/aaem.v12i1.2388","url":null,"abstract":"","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"12 1","pages":"e63"},"PeriodicalIF":2.9,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11407529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stroke and COVID-19: An Umbrella Review.","authors":"Kavous Shahsavarinia, Nasim Hajipoor Kashgsaray, Morteza Ghojazadeh, Zahra Falaki, Maryam Soleimanpour, Hassan Soleimanpour","doi":"10.22037/aaem.v12i1.2385","DOIUrl":"https://doi.org/10.22037/aaem.v12i1.2385","url":null,"abstract":"<p><strong>Introduction: </strong>Acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH) are among the acute cerebrovascular diseases (CVDs) that have been reported as a result of COVID-19. It will be a significant step forward if our research helps improve the compilation and analysis of existing data from other studies.</p><p><strong>Methods: </strong>The study is registered on PROSPERO with an ID of CRD42023464058. It encompasses articles published until December 2023 and involves searching databases such as PubMed, Scopus, Web of Knowledge, Embase, and Cochrane. Additionally, we conducted manual searches in respected publications within this discipline, utilized the Google Scholar search engine, and conducted reference checks, citation checks, and study of gray literature. The publications' reporting quality was assessed using the \"Assessment of Multiple Systematic Reviews\" (AMSTAR) checklist. The meta-analysis was conducted using Stata software (StataCorp, version 16).</p><p><strong>Results: </strong>We analyzed the findings of 23 meta-analyses, which included 795 articles and encompassed 5,937 patients who had previously experienced a stroke. The average age of these patients was 62.3 years, and 68.3% were male. The findings indicated that the collective incidence of stroke among individuals with COVID-19 is roughly 1.75% [95% confidence interval (CI): 0.4%-3.03], with 1.59% for ischemic strokes and 0.3% for hemorrhagic strokes. 32.3% (95% CI: 27.8%-36.9%) of COVID-19 patients with stroke passed away, approximately 27% were discharged from the hospital with very mild or no complications, and around 28.1% (95% CI: 14.1%-42.1%) were referred for rehabilitation.</p><p><strong>Conclusions: </strong>The overall rate of stroke in COVID-19 patients was approximately 1.75%, with a higher incidence in males and those with an average age of 62.3 years. Almost 80% of the strokes were ischemic, and the mortality rate was approximately 32%. Finally, 27% of the patients were discharged without complications, and 28% required rehabilitation.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"12 1","pages":"e65"},"PeriodicalIF":2.9,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11407545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}