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Effect of Oral Care with Povidone-Iodine in the Prevention of Ventilator-Associated Pneumonia; a Systematic Review and Meta-Analysis. 聚维酮碘口腔护理对呼吸机相关性肺炎的预防作用系统评价和荟萃分析。
IF 5.4
Archives of Academic Emergency Medicine Pub Date : 2023-01-01 DOI: 10.22037/aaem.v11i1.1874
Amir Emami Zeydi, Arman Parvizi, Soudabeh Haddadi, Samad Karkhah, Seyed Javad Hosseini, Amirabbas Mollaei, Mahbobeh Firooz, Shahin Ramezani, Joseph Osuji, Pooyan Ghorbani Vajargah, Shadi Dehghanzadeh
{"title":"Effect of Oral Care with Povidone-Iodine in the Prevention of Ventilator-Associated Pneumonia; a Systematic Review and Meta-Analysis.","authors":"Amir Emami Zeydi,&nbsp;Arman Parvizi,&nbsp;Soudabeh Haddadi,&nbsp;Samad Karkhah,&nbsp;Seyed Javad Hosseini,&nbsp;Amirabbas Mollaei,&nbsp;Mahbobeh Firooz,&nbsp;Shahin Ramezani,&nbsp;Joseph Osuji,&nbsp;Pooyan Ghorbani Vajargah,&nbsp;Shadi Dehghanzadeh","doi":"10.22037/aaem.v11i1.1874","DOIUrl":"https://doi.org/10.22037/aaem.v11i1.1874","url":null,"abstract":"<p><strong>Introduction: </strong>Ventilator-associated pneumonia (VAP) is one of the most common nosocomial infections affecting one-third of patients with mechanical ventilation. This study aimed to synthesize available evidence regarding the effect of treatment with povidone-iodine (PI) among adult patients admitted to intensive care units (ICUs) for the prevention of VAP.</p><p><strong>Methods: </strong>An extensive search was conducted in online databases, including PubMed, Web of Science and Scopus, from the earliest records until January 1, 2023. STATA software v14 was used for statistical analysis. Publication bias was assessed via funnel plot, Begg's and Egger's tests. A P-value less than 0.1 was considered statistically significant for publication bias value.</p><p><strong>Results: </strong>Four studies were included in the meta-analysis. Three studies showed rhat PI decreased VAP compared to the placebo group, but it was not statistically significant (RR: 0.61, 95%CI: 0.25 to 1.47, Z=1.10, P=0.27, I2:71.5%). One study compared the effect of PI with chlorhexidine on the rate of VAP, the difference between which was not statistically significant (RR: 1.50, 95%CI: 0.46 to 4.87, Z=0.67, P=0.50, I2:0). Two studies demonstrated that the use of PI intervention compared to placebo decreased the average length of stay in ICU; however, it was not statistically significant (WMD: -0.35, 95%CI:-3.90 to 3.20, Z=0.19, P=0.85, I2:0). Also, three studies showed that using PI had almost no effect on mortality rate compared to placebo (RR: 1.05, 95%CI: 0.66 to 1.53, Z=0.8, P=0.27, I2:29.0%).</p><p><strong>Conclusion: </strong>More rigorously designed randomized clinical trials and further evidence are required to make a better decision/comparison about using PI as a suitable choice for preventing VAP among adult patients admitted to the ICU.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"11 1","pages":"e31"},"PeriodicalIF":5.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0c/1b/aaem-11-e31.PMC10197909.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9506102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic Value of CRASH and IMPACT Models for Predicting Mortality and Unfavorable Outcome in Traumatic Brain Injury; a Systematic Review and Meta-Analysis. CRASH和IMPACT模型预测颅脑外伤死亡率和不良结局的预后价值系统评价和荟萃分析。
IF 5.4
Archives of Academic Emergency Medicine Pub Date : 2023-01-01 DOI: 10.22037/aaem.v11i1.1885
Hamed Zarei, Mohammadhossein Vazirizadeh-Mahabadi, Hamzah Adel Ramawad, Arash Sarveazad, Mahmoud Yousefifard
{"title":"Prognostic Value of CRASH and IMPACT Models for Predicting Mortality and Unfavorable Outcome in Traumatic Brain Injury; a Systematic Review and Meta-Analysis.","authors":"Hamed Zarei,&nbsp;Mohammadhossein Vazirizadeh-Mahabadi,&nbsp;Hamzah Adel Ramawad,&nbsp;Arash Sarveazad,&nbsp;Mahmoud Yousefifard","doi":"10.22037/aaem.v11i1.1885","DOIUrl":"https://doi.org/10.22037/aaem.v11i1.1885","url":null,"abstract":"<p><strong>Introduction: </strong>The Corticosteroid Randomization After Significant Head injury (CRASH) and the International Mission for Prognosis and Analysis of Clinical Trials (IMPACT) are two prognostic models frequently used in predicting the outcome of patients with traumatic brain injury. There are ongoing debates about which of the two models has a better prognostic value. This study aims to compare the CRASH and IMPACT in predicting mortality and unfavorable outcome of patients with traumatic brain injury.</p><p><strong>Method: </strong>We performed a literature search using Medline (via PubMed), Embase, Scopus, and Web of Science databases until August 17, 2022. After two independent researchers screened the articles, we included all the original articles comparing the prognostic value of IMPACT and CRASH models in patients with traumatic brain injury. The outcomes evaluated were mortality and unfavorable outcome. The data of the included articles were analyzed using STATA 17.0 statistical program, and we reported an odds ratio (OR) with a 95% confidence interval (95% CI) for comparison.</p><p><strong>Results: </strong>We included the data from 16 studies. The analysis showed that the areas under the curve of the IMPACT core model and CRASH basic model do not differ in predicting the mortality of patients (OR=0.99; p=0.905) and their six-month unfavorable outcome (OR=1.01; p=0.719). Additionally, the CRASH CT model showed no difference from the IMPACT extended (OR=0.98; p=0.507) and IMPACT Lab (OR=1.00; p=0.298) models in predicting the mortality of patients with traumatic brain injury. We also observed similar findings in the six-month unfavorable outcome, showing that the CRASH CT model does not differ from the IMPACT extended (OR=1.00; p=0.990) and IMPACT Lab (OR=1.00; p=0.570) in predicting the unfavorable outcome in head trauma patients.</p><p><strong>Conclusion: </strong>Low to very low level of evidence shows that IMPACT and CRASH models have similar values in predicting mortality and unfavorable outcome in patients with traumatic brain injury. Since the discriminative power of the IMPACT Core and CRASH basic models is not different from the IMPACT extended, IMPACT Lab, and CRASH CT models, it may be possible to only use the core and basic models in examining the prognosis of patients with traumatic injuries to the brain.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"11 1","pages":"e27"},"PeriodicalIF":5.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/66/bf/aaem-11-e27.PMC10008242.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9128879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Out-Of-Hour Admission on Fluid Treatment of Emergency Department Patients with Suspected Infection; a Multicenter Post-Hoc Analysis. 非分时入院对急诊疑似感染患者输液治疗的影响多中心事后分析。
IF 5.4
Archives of Academic Emergency Medicine Pub Date : 2023-01-01 DOI: 10.22037/aaem.v11i1.1839
Marie Kristine Jessen, Anna Drescher Petersen, Hans Kirkegaard
{"title":"Effect of Out-Of-Hour Admission on Fluid Treatment of Emergency Department Patients with Suspected Infection; a Multicenter Post-Hoc Analysis.","authors":"Marie Kristine Jessen,&nbsp;Anna Drescher Petersen,&nbsp;Hans Kirkegaard","doi":"10.22037/aaem.v11i1.1839","DOIUrl":"https://doi.org/10.22037/aaem.v11i1.1839","url":null,"abstract":"<p><strong>Introduction: </strong>Sepsis is a life-threatening and common cause of Emergency department (ED) referrals. Out-of-hour staffing is limited in ED, which may potentially affect fluid administration. This study aimed to investigate fluid volume variation in out-of-hour vs. routine-hour admissions.</p><p><strong>Methods: </strong>The present study is a post-hoc analysis of a multicentre, prospective, observational study investigating fluid administration in ED patients with suspected infection, from Jan 20<sup>th</sup> - March 2<sup>nd,</sup> 2020. Patient groups were \"routine-hours\" (RH): weekdays 07:00-18:59 or \"out-of-hours\" (OOH): weekdays 19:00-06:59 or Friday 19:00-Monday 06:59. Primary outcome was 24-hour total fluid volumes (oral + intravenous (IV)). Secondary outcomes were total fluids 0-6 hours, oral fluids 0-6 and 0-24 hours, and IV fluids 0-6 and 0-24 hours. Linear regression adjusted for site and illness severity was used.</p><p><strong>Results: </strong>734 patients had suspected infection; 449 were admitted during RH and 287 during OOH. Mean (95% CI) total 24-hour fluid volumes were equal in simple infection and sepsis regardless of admission time: Simple infection RH: 3640 (3410 - 3871) ml and OOH: 3681 (3451 - 3913) ml. Sepsis RH: 3671 (3443;3898) ml and OOH: 3896 (3542;4250) ml. Oral fluids 0-6h were reduced in simple infection and sepsis among OOH vs. RH. Sepsis patients received more 0-6-hour IV fluid when admitted OOH vs. RH. There were no associations between admission time and 0-24-hour oral or IV volumes in simple infection or sepsis.</p><p><strong>Conclusion: </strong>Admission time did not have an association with 24-hour total fluid volumes. Sepsis patients admitted during OOH received more 0-6-hour IV fluids than RH patients, and simple infection and sepsis patients received less oral fluid in 0-6 hours if admitted during OOH vs. RH.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"11 1","pages":"e21"},"PeriodicalIF":5.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/12/e3/aaem-11-e21.PMC10008217.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9617183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of L-Citrulline Supplementation on Outcomes of Critically Ill Patients under Mechanical Ventilation; a Double-Blind Randomized Controlled Trial. 补充l -瓜氨酸对危重患者机械通气预后的影响一项双盲随机对照试验。
IF 5.4
Archives of Academic Emergency Medicine Pub Date : 2023-01-01 DOI: 10.22037/aaem.v11i1.1774
Mohammad Reza Asgary, Sayid Mahdi Mirghazanfari, Ebrahim Hazrati, Vahid Hadi, Mojgan Mehri Ardestani, Faeze Bani Yaghoobi, Saeid Hadi
{"title":"The Effect of L-Citrulline Supplementation on Outcomes of Critically Ill Patients under Mechanical Ventilation; a Double-Blind Randomized Controlled Trial.","authors":"Mohammad Reza Asgary,&nbsp;Sayid Mahdi Mirghazanfari,&nbsp;Ebrahim Hazrati,&nbsp;Vahid Hadi,&nbsp;Mojgan Mehri Ardestani,&nbsp;Faeze Bani Yaghoobi,&nbsp;Saeid Hadi","doi":"10.22037/aaem.v11i1.1774","DOIUrl":"https://doi.org/10.22037/aaem.v11i1.1774","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Effective parenteral and enteral amino acid replacement is crucial for critically ill patients with altered amino acid metabolism. This study aimed to assess the effects of l-citrulline supplementation on the clinical and laboratory outcomes in critically patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This was a double-blind placebo-controlled randomized clinical trial. 82 critically ill patients who were expected to receive mechanical ventilation for more than 72 hours were selected. The patients were assigned to either a placebo or an intervention group. The patients in the placebo group received 10 gr of microcrystalline cellulose and the ones in the intervention group were given l-citrulline daily for 7 days. Serum levels of fasting blood sugar (FBS), lipid profile, hepatic enzymes, serum electrolytes, urea nitrogen, creatinine, and C-reactive protein (CRP) were evaluated before and after the intervention. Duration of invasive ventilation, intensive care unit (ICU) length of stay, ventilator-free days, and 28-day mortality rate were recorded and compared between groups.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Eighty-two patients completed the trial. No statistically significant differences were observed between the two groups in terms of age (p = 0.46), sex (p = 0.49), body mass index (BMI) (p = 0.41), Sequential Organ Failure Assessment (SOFA) Score (p = 0.08), Clinical Pulmonary Infection Score (CPIS) score (p = 0.76), Acute Physiology and Chronic Health Evaluation (APACHE II) score (p = 0.58), risk factors (p = 0.13), ICU stay before randomization (p = 0.32), and reason of admission (p = 0.50) before the intervention. Citrulline group had a notable reduction in FBS (p = 0.04), total cholesterol (TC) (p = 0.02), low density lipoprotein (LDL-C) (p &lt;0.001) and high-sensitivity CRP (hs-CRP) (p &lt;0.001). Also, a significant increase in lactate dehydrogenase (LDH) concentration (p &lt;0.001) was observed in the intervention group at the end of the trial. Total duration of invasive ventilation and the mean SOFA score on 7th day were significantly lower in the citrulline group compared to the control group. Moreover, a significant increase in days alive and ventilator-free days within 28 days after admission was found in the citrulline group at the end of the trial. Also, there were no significant differences between the groups in terms of mortality rate during intervention, serious adverse events, endotracheal intubation, the use of tracheotomy or non-invasive ventilation after extubation, length of ICU stay, ICU-free days at 28 days, and CPIS and APACHE II scores. For mortality, in the citrulline group, there was two deaths compared to eight deaths in the control group. This resulted in an absolute risk reduction (ARR) of 14.05% (95% CI: 0.39-27.71%) and a number needed to treat (NNT) of 7.1 (95% CI: 3.6-29.5), regarding mortality.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The results of the present study demonstrated the probable pos","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"11 1","pages":"e11"},"PeriodicalIF":5.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/65/c3/aaem-11-e11.PMC9807954.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10500462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Point-Of-Care Ultrasonography for Identification of Skin and Soft Tissue Abscess in Adult and Pediatric Patients; a Systematic Review and Meta-Analysis. 成人及儿童皮肤软组织脓肿的即时超声诊断系统评价和荟萃分析。
IF 5.4
Archives of Academic Emergency Medicine Pub Date : 2023-01-01 DOI: 10.22037/aaem.v11i1.2021
Erfan Rahmani, Ehsan Fayyazishishavan, Arian Afzalian, Sanaz Varshochi, Reza Amani-Beni, Seyed-Amirabbas Ahadiat, Zeynab Moshtaghi, Seyyed-Ghavam Shafagh, Roya Khorram, Elnaz Asadollahzade, Raihaneh Atbaei, Mohammad Saeed Kahrizi, Atoosa Rahbari, Negar Baharlouie, Farzaneh Mostanbet, Bahamin Amirabadiquchani, Moein Kiani, Mozhdeh Memarizadeh, Shahin Keshtkar Rajabi, Reza Barati, Hengame Hajinouri, Shahrzad Najafi, Zeynab Abdollahi, Nahid Dadashzadehasl, Atousa Moghadam Fard, Mozhgan Afshar, Atefeh Abedi, Sara Saeidi, Adeleh Mansourirad, Pedram Emami Shahrezaei, Sepideh Shah Hosseini, Zahra Rostami Ghotbabadi, Reza Vafadar, Roozbeh Roohinezhad, Nogol Ghalamkarpour, Mehrdad Farrokhi
{"title":"Point-Of-Care Ultrasonography for Identification of Skin and Soft Tissue Abscess in Adult and Pediatric Patients; a Systematic Review and Meta-Analysis.","authors":"Erfan Rahmani,&nbsp;Ehsan Fayyazishishavan,&nbsp;Arian Afzalian,&nbsp;Sanaz Varshochi,&nbsp;Reza Amani-Beni,&nbsp;Seyed-Amirabbas Ahadiat,&nbsp;Zeynab Moshtaghi,&nbsp;Seyyed-Ghavam Shafagh,&nbsp;Roya Khorram,&nbsp;Elnaz Asadollahzade,&nbsp;Raihaneh Atbaei,&nbsp;Mohammad Saeed Kahrizi,&nbsp;Atoosa Rahbari,&nbsp;Negar Baharlouie,&nbsp;Farzaneh Mostanbet,&nbsp;Bahamin Amirabadiquchani,&nbsp;Moein Kiani,&nbsp;Mozhdeh Memarizadeh,&nbsp;Shahin Keshtkar Rajabi,&nbsp;Reza Barati,&nbsp;Hengame Hajinouri,&nbsp;Shahrzad Najafi,&nbsp;Zeynab Abdollahi,&nbsp;Nahid Dadashzadehasl,&nbsp;Atousa Moghadam Fard,&nbsp;Mozhgan Afshar,&nbsp;Atefeh Abedi,&nbsp;Sara Saeidi,&nbsp;Adeleh Mansourirad,&nbsp;Pedram Emami Shahrezaei,&nbsp;Sepideh Shah Hosseini,&nbsp;Zahra Rostami Ghotbabadi,&nbsp;Reza Vafadar,&nbsp;Roozbeh Roohinezhad,&nbsp;Nogol Ghalamkarpour,&nbsp;Mehrdad Farrokhi","doi":"10.22037/aaem.v11i1.2021","DOIUrl":"https://doi.org/10.22037/aaem.v11i1.2021","url":null,"abstract":"<p><strong>Introduction: </strong>Differentiating the soft tissue abscess from other types of skin and soft tissue infections (SSTIs) poses a particular challenge because they have similar physical evaluation findings, but each disease has a different course, outcome, and treatment. This meta-analysis aimed to investigate the diagnostic accuracy of point-of-care ultrasonography for diagnosis of soft tissue abscess in the emergency departments.</p><p><strong>Methods: </strong>A comprehensive literature search of MEDLINE, Scopus, Web of Science, Embase, and Google Scholar, from inception to January 2023, was conducted to identify relevant studies investigating the diagnostic performance of point-of-care ultrasonography for identification of abscess. Methodological quality of the included studies was assessed using a revised tool for the quality assessment of diagnostic accuracy studies (QUADAS-2).</p><p><strong>Results: </strong>The pooled estimates of diagnostic parameters of ultrasonography for diagnosis of abscess were as follows: sensitivity, 0.93 (95% CI: 0.92-0.94); specificity, 0.87 (95% CI: 0.85-0.89), and the area under the summary receiver-operating characteristic (SROC), 0.95. The pooled sensitivity, specificity, and area under the SROC of studies in adult patients were 0.98 (95% CI: 0.92-1), 0.92 (95% CI: 0.86-0.95), and 0.99, respectively. The pooled sensitivity, specificity, and area under the SROC of studies in pediatric patients were 0.9 (95% CI: 0.87-0.92), 0.78 (95% CI: 0.73-0.82), and 0.91, respectively.</p><p><strong>Conclusion: </strong>Our meta-analysis demonstrated that the point-of-care ultrasonography has excellent diagnostic value for the abscess in the emergency department. Furthermore, we found that the diagnostic performance of point-of-care ultrasonography for diagnosis of abscess was higher for adult cases than for pediatric patients.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"11 1","pages":"e49"},"PeriodicalIF":5.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c4/10/aaem-11-e49.PMC10440756.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10055732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HEART versus GRACE Score in Predicting the Outcomes of Patients with Acute Coronary Syndrome; a Systematic Review and Meta-Analysis. HEART与GRACE评分预测急性冠脉综合征患者预后的比较系统评价和荟萃分析。
IF 5.4
Archives of Academic Emergency Medicine Pub Date : 2023-01-01 DOI: 10.22037/aaem.v11i1.2001
Ali Kabiri, Pantea Gharin, Seyed Ali Forouzannia, Koohyar Ahmadzadeh, Reza Miri, Mahmoud Yousefifard
{"title":"HEART versus GRACE Score in Predicting the Outcomes of Patients with Acute Coronary Syndrome; a Systematic Review and Meta-Analysis.","authors":"Ali Kabiri,&nbsp;Pantea Gharin,&nbsp;Seyed Ali Forouzannia,&nbsp;Koohyar Ahmadzadeh,&nbsp;Reza Miri,&nbsp;Mahmoud Yousefifard","doi":"10.22037/aaem.v11i1.2001","DOIUrl":"https://doi.org/10.22037/aaem.v11i1.2001","url":null,"abstract":"<p><strong>Introduction: </strong>Several scoring systems have been proposed to predict the outcomes of patients with ischemic heart disease. Global Registry of Acute Coronary Events (GRACE) and History, ECG, Age, Risk Factors, and Troponin (HEART) scores are two of the more widely used risk prediction tools in patients with acute coronary syndrome (ACS). The present systematic review and meta-analysis aimed to compare the value of GRACE and HEART scores in the outcome prediction of ACS patient.</p><p><strong>Method: </strong>The online databases of Medline, Embase, Web of Science, and Scopus were search until September 2022 for articles directly comparing GRACE and HEART scores value in prediction of outcome in patients with ACS. GRACE score cut-offs were categorized into two groups of less than and equal to 100 and more than 100, and HEART score cut-offs were categorized into three groups of less than 4, equal to 4, and more than 4. Investigated outcomes were major adverse cardiovascular events (MACE), acute myocardial infraction (AMI) and all-cause mortality.</p><p><strong>Results: </strong>25 articles were included. The sensitivity and specificity of the GRACE score for prediction of MACE were 0.96 and 0.26 for cut-offs of ≤ 100, and 0.58 and 0.69 for cut-offs of >100, respectively. The sensitivity and specificity of the HEART score for prediction of MACE were 0.99 and 0.16 for cut-offs less than 4, 0.93 and 0.47 for equal to 4, and 0.77 and 0.78 for cut-offs greater than 4. GRACE score was shown to be predictive of AMI with sensitivity and specificity of 0.95 and 0.29, respectively. The analysis for the value of HEART score in the prediction of AMI a sensitivity and specificity of 0.94 and 0.48, respectively. The risk scores were not found to be suitable predictors of all-cause mortality.</p><p><strong>Conclusion: </strong>The results demonstrated the low specificity of GRACE and HEART scores in predicting the MACE, AMI and all-cause mortality, irrespective of the utilized cut-off. Considering the acceptable sensitivity of two scores in predicting the MACE and AMI, these scores were more suitable to be used as a rule-out tool for identification of ACS patients with low risk of developing adverse outcomes.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"11 1","pages":"e50"},"PeriodicalIF":5.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/13/7b/aaem-11-e50.PMC10440758.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10061426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing the Emergency Medicine Residency Programs in Iran and around the World; a Descriptive Study. 伊朗与世界各国急诊医学住院医师制度比较描述性研究。
IF 5.4
Archives of Academic Emergency Medicine Pub Date : 2023-01-01 DOI: 10.22037/aaem.v11i1.1867
Mahdi Talebi, Morteza Talebi Doluee, Mohamadali Jafari, Hamid Zamani Moghaddam, Mahdi Foroughian, Mojtaba Moazzami, Hassan Gholami, Hamidreza Reihani
{"title":"Comparing the Emergency Medicine Residency Programs in Iran and around the World; a Descriptive Study.","authors":"Mahdi Talebi,&nbsp;Morteza Talebi Doluee,&nbsp;Mohamadali Jafari,&nbsp;Hamid Zamani Moghaddam,&nbsp;Mahdi Foroughian,&nbsp;Mojtaba Moazzami,&nbsp;Hassan Gholami,&nbsp;Hamidreza Reihani","doi":"10.22037/aaem.v11i1.1867","DOIUrl":"https://doi.org/10.22037/aaem.v11i1.1867","url":null,"abstract":"<p><strong>Introduction: </strong>To identify the strengths and weaknesses of emergency medicine residency curriculum in Iran, and to benefit from the experiences of successful universities, comparative studies are crucial. This study compared the components of the national curriculum of emergency medicine in the United States, Canada, the European Union, Australia, and Saudi Arabia with Iran.</p><p><strong>Method: </strong>Data for this research was collected by searching the websites of different universities and also contacting them for requesting curriculums. The leading countries in emergency medicine and one of the countries in the Middle East region (Saudi Arabia) along with the World Federation of Emergency Medicine were selected as the sample. The model used in this field is a range model that identifies four stages of description, interpretation, proximity, and comparison in comparative studies.</p><p><strong>Results: </strong>In the curriculum of the United States, Canada, the European Union, Australia, and Saudi Arabia, there were lots of similarities in expressing the general characteristics of the curriculum, mission elements, vision, values, and ​beliefs of the discipline, educational strategy, techniques, expected competencies, rotation programs, and evaluation method, which were also similar to the Iranian curriculum. However, the duration of residency for emergency medicine in Iran is three years, which is shorter than other countries. As expected, the number and duration of rotations are less than other countries. Also, the process of entering into this field is different in Iran and is based on an exam for entrance, while most other countries use self-requested residency program.</p><p><strong>Conclusion: </strong>Considering the results of comparing the Iranian curriculum with the curriculums of the United States, Canada, the European Union, Australia, and Saudi Arabia, it seems that Iran's program is comprehensive and complete; but, a reappraisal of the course duration and entering options are necessary to eliminate or improve the inadequacies.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"11 1","pages":"e13"},"PeriodicalIF":5.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1f/05/aaem-11-e13.PMC9807940.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10507413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Periosteal Nerve Block Vs. Intravenous Morphine in Pain Relief of Distal Radius and Ulna Fracture; a Double-Blind Randomized Clinical Trial. 骨膜神经阻滞与静脉吗啡对桡骨、尺骨远端骨折疼痛的缓解作用一项双盲随机临床试验
IF 5.4
Archives of Academic Emergency Medicine Pub Date : 2023-01-01 DOI: 10.22037/aaem.v11i1.2056
Shadi Ashtari, Alireza Hasanzadeh, Alireza Bahmani, Ali Abdolrazaghnejad
{"title":"Periosteal Nerve Block Vs. Intravenous Morphine in Pain Relief of Distal Radius and Ulna Fracture; a Double-Blind Randomized Clinical Trial.","authors":"Shadi Ashtari,&nbsp;Alireza Hasanzadeh,&nbsp;Alireza Bahmani,&nbsp;Ali Abdolrazaghnejad","doi":"10.22037/aaem.v11i1.2056","DOIUrl":"https://doi.org/10.22037/aaem.v11i1.2056","url":null,"abstract":"<p><strong>Introduction: </strong>Distal forearm fractures' realignment and fixation is a painful procedure. This study aimed to compare the efficacy of periosteal nerve block and intravenous morphine in distal radius and ulna fractures' pain management.</p><p><strong>Methods: </strong>In the present randomized, parallel, double-blind, controlled clinical trial, patients with distal radius or ulna fractures were divided into two groups. In the first group, for periosteal nerve block, 1% lidocaine was injected at a distance of 6 to 8 cm near the wrist from the lateral radius and medial ulna. In the second group, morphine sulfate at a dose of 0.1 mg/kg was slowly injected through the peripheral vein within 5 minutes. The visual analog scale (VAS) score was evaluated before the intervention and every 15 minutes until 90 minutes after the intervention and was compared between the two groups.</p><p><strong>Results: </strong>75 subjects were studied (39 in the periosteal nerve block and 36 in the intravenous morphine group). There were no significant differences between the groups in terms of mean age (p = 0.384), gender distribution (p = 0.464), past medical history (p = 0.106), trauma type (p = 0.836), fracture type (p = 0.613), and baseline pain severity on VAS (p = 0.987). Both methods reduced the VAS scores during the 90 minutes of the study. The mean pain scores of the patients in the periosteal nerve block group with 2.56±1.44, 2.15±1.11, 2.66±1.26, and 3±1.27 at 15, 30, 45, and 60 minutes after the analgesic injection, respectively, were significantly lower than those of the intravenous morphine group with 4.75±1.27, 4.22±1.22, 3.97±1.27, and 4.13±1.35, respectively (p < 0.001 for all comparisons). In the present study, no local or systemic complications were observed in the periosteal nerve block group, while the complications of dyspnea, vomiting, and pruritus were reported by 5.5%, 2.8%, and 2.8%, respectively, in the intravenous morphine group. Moreover, the percentage of need for additional analgesia in the intravenous morphine group was higher than that of the periosteal nerve block group.</p><p><strong>Conclusion: </strong>In the first hour after the intervention, pain reduction in periosteal block was significantly higher than intravenous morphine administration. Also, the incidence of complications and the need for additional analgesia were lower in the periosteal block group compared to intravenous morphine administration.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"11 1","pages":"e51"},"PeriodicalIF":5.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/96/a1/aaem-11-e51.PMC10475742.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10170198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing Emergency Response through Artificial Intelligence in Emergency Medical Services Dispatching; a Letter to Editor. 利用人工智能提高医疗急救调度中的应急响应能力给编辑的信。
IF 5.4
Archives of Academic Emergency Medicine Pub Date : 2023-01-01 DOI: 10.22037/aaem.v11i1.2097
Payam Emami, Karim Javanmardi
{"title":"Enhancing Emergency Response through Artificial Intelligence in Emergency Medical Services Dispatching; a Letter to Editor.","authors":"Payam Emami,&nbsp;Karim Javanmardi","doi":"10.22037/aaem.v11i1.2097","DOIUrl":"https://doi.org/10.22037/aaem.v11i1.2097","url":null,"abstract":"The emergency medical dispatcher (EMD) serves as a crucial link between individuals in need of emergency medical assistance and the emergency medical services (EMS) resource delivery system. Through their expertise and training, EMDs are able to accurately assess emergency situations, provide appropriate guidance over the phone, and dispatch the necessary EMS personnel to the scene. With adequate training, program management, supervision, and medical guidance, the EMD can accurately assess the caller’s needs, choose an appropriate response approach, furnish relevant information to responders, and offer suitable assistance and guidance to patients through the caller. By diligently adhering to a written and medically approved EMD protocol, informed decisions regarding EMS responses can be made in a reliable, replicable, and fair manner (1, 2). Artificial intelligence (AI) is the concept of a computer program that utilizes existing information to make decisions and enhances its performance based on accumulated experience. Machine learning (ML), a crucial aspect of AI,","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"11 1","pages":"e60"},"PeriodicalIF":5.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/67/a9/aaem-11-e60.PMC10475749.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10225842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Short-term Side Effects of mRNA-based COVID-19 Vaccine Among Jordanian Population; a Cross-sectional Study. 基于mrna的新型冠状病毒疫苗在约旦人群中的短期副作用横断面研究
IF 5.4
Archives of Academic Emergency Medicine Pub Date : 2023-01-01 DOI: 10.22037/aaem.v11i1.1850
Razan I Nassar
{"title":"Short-term Side Effects of mRNA-based COVID-19 Vaccine Among Jordanian Population; a Cross-sectional Study.","authors":"Razan I Nassar","doi":"10.22037/aaem.v11i1.1850","DOIUrl":"https://doi.org/10.22037/aaem.v11i1.1850","url":null,"abstract":"<p><strong>Introduction: </strong>One type of the developed COVID-19 vaccines that received emergency permission and was approved by the food and drug administration (FDA) is the mRNA-based vaccine. The aim of this study is to gather information on the Jordanian population's experience with the vaccine's side effects.</p><p><strong>Methods: </strong>The study objectives were addressed through a cross-sectional study, which collected information regarding the short-term side effects experienced by the vaccinated individuals within one month following the injection of an mRNA-based COVID-19 vaccine. Data collection was carried out in August 2021. Participants were invited to take part in a self-administered web-based survey created using Google Forms.</p><p><strong>Results: </strong>Among the study's participants (n= 533), about 56% experienced side effects after the first dose of the mRNA-based COVID-19 vaccine. The most commonly reported side effects after the first dose were sore arm at the injection site (91.6%), and fatigue (83.06%). The female gender was significantly associated with experiencing fatigue, discomfort, chills, and hair loss. Being over 30 years old was significantly associated with experiencing cough. Being a smoker was significantly associated with experiencing shortness of breath and gastrointestinal symptoms.</p><p><strong>Conclusion: </strong>The mRNA-based COVID-19 vaccine side effects were common, yet, mild, local, and self-limited. The local pain at the injection site was the most commonly reported side effect. Hopefully, the study's findings will aid in lowering resistance to vaccination.</p>","PeriodicalId":8146,"journal":{"name":"Archives of Academic Emergency Medicine","volume":"11 1","pages":"e22"},"PeriodicalIF":5.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/70/dc/aaem-11-e22.PMC10008238.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9128877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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