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Annals of clinical research最新文献

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Fatal asthma in two regions of Finland. 芬兰两个地区的致命哮喘。
Annals of clinical research Pub Date : 1988-01-01
V Kinnula, T Nurmela, K Liippo, E Tala, E Huhti
{"title":"Fatal asthma in two regions of Finland.","authors":"V Kinnula,&nbsp;T Nurmela,&nbsp;K Liippo,&nbsp;E Tala,&nbsp;E Huhti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To determine the factors associated with deaths from asthma we surveyed retrospectively all the death certificates issued in two regions of Finland (the province of Oulu and the province of Turku and Pori) over a ten-year period in which asthma had been given as the main cause of death. We then examined patients' records to check whether asthma was the main cause of death. A total of 156 deaths could be ascribed to asthma, 87 in patients under 65 at death and 69 over 65. More deaths tended to occur during the weekends, and in the younger age group more occurred during the night than by day. Previous drug treatment was considered inadequate in 45% of the cases. The management and drug treatment of the final exacerbation phase were also often inadequate, at least among the younger victims, and the terminal attack was usually short, death often occurring in three hours or less. Despite the shortcomings in treatment, the number of deaths from asthma in the younger age group has fallen in the province of Oulu over the last 20 years.</p>","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"20 3","pages":"189-94"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14325085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum lipids in pneumonia of different aetiology. 不同病因肺炎的血脂。
Annals of clinical research Pub Date : 1988-01-01
Y Kerttula, T Weber
{"title":"Serum lipids in pneumonia of different aetiology.","authors":"Y Kerttula,&nbsp;T Weber","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The changes in serum triglycerides, cholesterol and high density lipoprotein (HDL) cholesterol were followed in patients with pneumonia caused by different bacteria or viruses as well as in those with no defined aetiology. In the acute phase of the disease there was: 1) a fall in serum triglycerides in patients with bacteremic pneumococcal disease and in patients with no defined aetiology (p less than 0.01 and less than 0.005, respectively). 2) a reduction in cholesterol in all aetiological groups (p less than 0.001) except for those with viral pneumonias, where only 4 patients were studied, and 3) a fall in HDL cholesterol in all the groups (at least at p less than 0.05) except in those with virus infection. 4) In bacteraemic pneumococcal disease the cholesterol level (mean 2.6, SEM 0.3 mmol/l) was lower than that in the other groups (at least at p less than 0.05). In the acute phase there was a tendency to a negative correlation of erythrocyte sedimentation rate and of C-reactive protein with serum cholesterol and/or HDL cholesterol. Changes in serum lipids in various infections deserve further pathophysiological investigation.</p>","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"20 3","pages":"184-8"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14325208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The sauna and body fluid balance. 桑拿和体液平衡。
Annals of clinical research Pub Date : 1988-01-01
E Ahonen, U Nousiainen
{"title":"The sauna and body fluid balance.","authors":"E Ahonen,&nbsp;U Nousiainen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sauna bathing may affect the fluid, electrolyte and acid-base balance. In addition to sweating and thirst, a sauna bath also has effects on many endogenous regulatory mechanisms maintaining the balance between the fluid compartments and appropriate distribution of the circulating blood. Although the sauna-induced fluid loss is usually not very severe, its adequate replacement as early as possible is important. In practice, the most convenient and effective way is to replace the fluid loss by small liquid doses repeated frequently during the bathing. If a sauna bath is taken after heavy physical activity, the fluid compensation may be necessary already before bathing.</p>","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"20 4","pages":"257-61"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14345896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors affecting suitability for coronary bypass surgery. 影响冠状动脉搭桥手术适宜性的因素。
Annals of clinical research Pub Date : 1988-01-01
H Vik-Mo, R Danielsen, J Nordrehaug, L Stangeland
{"title":"Factors affecting suitability for coronary bypass surgery.","authors":"H Vik-Mo,&nbsp;R Danielsen,&nbsp;J Nordrehaug,&nbsp;L Stangeland","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Factors responsible for unsuitability for bypass surgery were assessed prospectively in 324 consecutive patients with serious angina pectoris undergoing cardiac catheterization. One hundred patients were found to be unsuitable for surgery (31%). These patients usually had peripheral coronary atherosclerosis (44%), stenotic/occluded artery distributing to an infarcted (35%) or small area (25%), or reduced global left ventricular (LV) function (15%). Age over 65 years (p less than 0.05), female sex (p less than 0.05), previous myocardial infarction (p less than 0.05), 1-vessel disease (p less than 0.01) and a low LV ejection fraction (p less than 0.01) occurred more often in patients not accepted for surgery. Of the patients with 3-vessel disease 75% were referred for surgery while only 25% of patients with 1-vessel disease (p less than 0.001) Stepwise logistic regression analysis identified LV ejection fraction as an inverse predictor (p less than 0.001) and number of stenotic coronary arteries as a predictor (p less than 0.001) of suitability for surgery. Thus, peripheral coronary atherosclerosis and global LV function are the main factors determining unsuitability for coronary bypass surgery.</p>","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"20 6","pages":"399-403"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14392918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dietary lipids and ischaemic heart disease--progress in 20 years. 膳食脂质与缺血性心脏病——20年来的进展
Annals of clinical research Pub Date : 1988-01-01
A Keys
{"title":"Dietary lipids and ischaemic heart disease--progress in 20 years.","authors":"A Keys","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"20 1-2","pages":"97-101"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14534133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dementia-like, largely reversible syndrome after cranial irradiation and prolonged interferon treatment. 脑照射和长期干扰素治疗后的痴呆样，大部分可逆性综合征。
Annals of clinical research Pub Date : 1988-01-01
R Laaksonen, A Niiranen, M Iivanainen, K Mattson, L Holsti, M Färkkilä, K Cantell
{"title":"Dementia-like, largely reversible syndrome after cranial irradiation and prolonged interferon treatment.","authors":"R Laaksonen,&nbsp;A Niiranen,&nbsp;M Iivanainen,&nbsp;K Mattson,&nbsp;L Holsti,&nbsp;M Färkkilä,&nbsp;K Cantell","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An elderly man with small cell lung cancer developed a largely reversible, dementia-like syndrome after cranial irradiation and prolonged treatment with interferon (IFN). The development of the symptoms started 2 months after cranial irradiation following more than 2 years of IFN treatment. The behavioral impairment did not suggest any specific brain localization. The dementia-like behaviour may be due to a combined effect of irradiation and IFN.</p>","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"20 3","pages":"201-3"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13985995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minerals, trace elements and cardiovascular disease. An overview. 矿物质，微量元素和心血管疾病。概述。
Annals of clinical research Pub Date : 1988-01-01
J Virtamo, J K Huttunen
{"title":"Minerals, trace elements and cardiovascular disease. An overview.","authors":"J Virtamo,&nbsp;J K Huttunen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"20 1-2","pages":"102-13"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14176044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alterations in sodium-potassium regulation in mononuclear leucocytes from young borderline hypertensive and offspring of hypertensive patients. 年轻交界性高血压患者及其后代单核白细胞钠钾调节的改变。
Annals of clinical research Pub Date : 1988-01-01
J R Nielsen, K E Pedersen, N A Klitgaard, T Johansen
{"title":"Alterations in sodium-potassium regulation in mononuclear leucocytes from young borderline hypertensive and offspring of hypertensive patients.","authors":"J R Nielsen,&nbsp;K E Pedersen,&nbsp;N A Klitgaard,&nbsp;T Johansen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Membrane ion transports were investigated in lymphocytes from young normotensive and borderline hypertensive offspring with and without heredity for hypertension. Borderline hypertension per se was associated with an enhancement of sodium-potassium pump activity. Heredity per se was associated with increased sodium influx and ouabain-resistant sodium efflux.</p>","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"20 Suppl 48 ","pages":"58-60"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13615796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the left ventricular diastolic function in constrictive pericarditis by digitised M-mode echocardiography. 数字化m型超声心动图评价缩窄性心包炎左室舒张功能。
Annals of clinical research Pub Date : 1988-01-01
J E Nordrehaug, R Danielsen, H Vik-Mo
{"title":"Assessment of the left ventricular diastolic function in constrictive pericarditis by digitised M-mode echocardiography.","authors":"J E Nordrehaug,&nbsp;R Danielsen,&nbsp;H Vik-Mo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Digitised M-mode echocardiography was used to study the diastolic left ventricular function in ten patients with constrictive pericarditis. Each patient was matched for heart rate and stroke volume with a control patient who had normal left ventricular end-diastolic pressure and coronary arteries. All 20 patients underwent right and left cardiac catheterisation. In patients with constrictive pericarditis compared with controls, the median (range) left ventricular peak diameter lengthening rate, normalised for end-diastolic dimension, was 4.5 (2.5-8.0) s-1 and 2.9 (1.6-4.1) (p less than 0.01), and the rapid filling period fraction of diastole was 0.28 (0.18-0.37) and 0.37 (0.21-0.58) (p less than 0.05), while the mitral valve E-F slope was 20.1 (10.5-39.2) cm/s and 11.8 (7.6-14.5) (p less than 0.05), respectively. Thus, the early rate of left ventricular diameter lengthening is increased in constrictive pericarditis independent of heart rate and stroke volume, while the actual duration of the rapid filling period is decreased. These results, obtained noninvasively, extend the findings of previous invasive studies. The method may help in the difficult clinical diagnosis of constrictive pericarditis, although there is some overlap with the normal control range.</p>","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"20 3","pages":"164-8"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14325206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lungs and ventilation in sauna. 桑拿中的肺和通气。
Annals of clinical research Pub Date : 1988-01-01
L A Laitinen, A Lindqvist, M Heino
{"title":"Lungs and ventilation in sauna.","authors":"L A Laitinen,&nbsp;A Lindqvist,&nbsp;M Heino","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>For over a hundred years Finnish sauna has been documented as a physiotherapeutic method in respiratory diseases. Physiological changes of ventilation remain small (about 10%) in the sauna. Heat load, sauna air and sympathetic stimulation generally do not cause problems to the lungs. Electron microscopic studies have not shown irreversible damages to the airway epithelium. Sauna takers should avoid bathing during acute respiratory infections. Sympathomimetic drugs may provoke tachycardia and arrhythmias in the sauna.</p>","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"20 4","pages":"244-8"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14345894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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