Annals of clinical research最新文献_第10页

Deficiency of immunoglobulin A. 免疫球蛋白A缺乏。

Annals of clinical research Pub Date : 1987-01-01

T Klemola

引用次数: 0

Assessment of B- and T-cell function in immunodeficiency. 免疫缺陷患者B细胞和t细胞功能的评估。

Annals of clinical research Pub Date : 1987-01-01

J Eskola, O Ruuskanen

引用次数: 0

Psychoendocrine aspects of coping with distress. 心理内分泌方面应对痛苦。

Annals of clinical research Pub Date : 1987-01-01

M T Hyyppä

引用次数: 0

Psychological factors in cardiac arrhythmias. 心律失常的心理因素。

Annals of clinical research Pub Date : 1987-01-01

G Härtel

{"title":"Psychological factors in cardiac arrhythmias.","authors":"G Härtel","doi":"","DOIUrl":"","url":null,"abstract":"Autonomic nervous control of the heart and the blood vessels is essential for optimal physical performance. Afferent nerves conduct impulses to the vasomotor and cardioaccelerator and cardioinhibitor centres resulting in efferent sympathetic and vagus output. Information inputs also from the environment and the person's thought processes are mediated from the cortex by the hypothalamus, the limbic system, and the autonomic nervous system to the heart and blood vessels. Emotional factors like anger, anxiety, and fear increase sympathetic output and influence heart rate. On the other hand, fear and the feeling of being in a helpless situation causes intensive vagal activation with ensuing severe bradycardia or asystole and vasovagal syncope. Although psychologic factors can cause extreme grades of tachy- or bradycardia they usually have no acute deleterious effects in the normal heart. In the diseased heart, however, consequences may be hazardous. Emotional factors are known to increase ventricular arrhythmias either directly or indirectly by increasing heart rate and causing ischaemia as in coronary heart disease. In animal experiments ventricular fibrillation threshold is lowered by aversive conditions. In heart diseases with sudden death as a well known complication increased sympathetic activity may give rise to fatal arrhythmias. In man the evidence of psychologic factors as the cause of life-threatening arrhythmias and sudden death is mostly anecdotal or circumstantial. Well designed studies are needed to evaluate the role of psychologic factors in arrhythmias.","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"19 2","pages":"104-9"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14782837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unintended plasma exchange therapy in poliomyelitis: difficulties in the differential diagnosis of paralytic poliomyelitis and polyradiculitis. 脊髓灰质炎的非预期血浆交换治疗:麻痹性脊髓灰质炎和多根性炎鉴别诊断的困难。

Annals of clinical research Pub Date : 1987-01-01

M Färkkilä, E Kinnunen, T Hovi, M Iivanainen

引用次数: 0

Efficacy of diclofenac in a single prophylactic dose in postoperative pain. 双氯芬酸单剂量预防术后疼痛的疗效。

Annals of clinical research Pub Date : 1987-01-01

I Tigerstedt, L Janhunen, T Tammisto

{"title":"Efficacy of diclofenac in a single prophylactic dose in postoperative pain.","authors":"I Tigerstedt, L Janhunen, T Tammisto","doi":"","DOIUrl":"","url":null,"abstract":"Prophylactic diclofenac (Voltaren) in postoperative pain was studied in 60 surgical patients who underwent either abdominal (30 patients) or superficial (30 patients) surgery. During anaesthesia, no analgesic or narcotic drugs were given. Immediately after surgery, an intravenous infusion of 100 ml normal saline or saline with 75 mg of diclofenac was administered over 10 minutes under double-blind randomized conditions. The 2-hour study period was started when the patients complained of pain or half an hour after the end of anaesthesia. For pain relief during the study period, 4 mg of oxycodone was repeatedly given on demand. The initial mean pain intensity values were significantly higher after abdominal surgery than after superficial surgery but there were no statistically significant differences between diclofenac and placebo groups. The mean amount of oxycodone required after diclofenac was not significantly lower than after placebo (10.9 +/- 1.9 mg vs. 13.1 +/- 1.4 mg after abdominal surgery and 3.2 +/- 0.8 mg vs. 4.0 +/- 1.2 mg after superficial surgery). The pain relief obtained with oxycodone was similar after diclofenac and placebo. According to the present results, prophylactic use of diclofenac does not significantly reduce the need for narcotic analgesics in the immediate postoperative phase in general surgery.","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"19 1","pages":"18-22"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14677712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Constipation in elderly long-stay patients: its treatment by magnesium hydroxide and bulk-laxative. 老年长期住院病人的便秘:氢氧化镁和大剂量泻药的治疗。

Annals of clinical research Pub Date : 1987-01-01

O Kinnunen, J Salokannel

引用次数: 0

Distribution of thyroid diseases and evaluation of laboratory parameters used in their diagnosis. 甲状腺疾病的分布及其诊断所用实验室参数的评价。

Annals of clinical research Pub Date : 1987-01-01

M A Al-Awqati, M Hassan, N Khamash

引用次数: 0

Assessment of exercise tolerance of cardiac patients by bicycle, treadmill and treadmill plus isometric exercise with and without nifedipine. 评估心脏病患者在有硝苯地平和不含硝苯地平的情况下骑自行车、跑步机和跑步机加等距运动的运动耐受性。

Annals of clinical research Pub Date : 1987-01-01

I Vuori, H Hämäläinen, J Pietilä, V Kallio

{"title":"Assessment of exercise tolerance of cardiac patients by bicycle, treadmill and treadmill plus isometric exercise with and without nifedipine.","authors":"I Vuori, H Hämäläinen, J Pietilä, V Kallio","doi":"","DOIUrl":"","url":null,"abstract":"Seventeen post-myocardial infarction patients experiencing angina on effort performed 6 different exercise tests until they reached symptom-limited maximal level, 3 after placebo and 3 after oral administration of 10 mg of the Calcium antagonist, nifedipine, in a randomized, double blind, cross-over controlled study. Four of the tests were conventional bicycle and treadmill tests with stepwise increasing load. In 2 of the tests an isometric exercise of carrying a weight averaging 6 kg and corresponding to about 30% of maximal grip strength was added to the treadmill walking. When the exercise was stopped because of moderately severe angina, the product of heart rate and systolic blood pressure did not show any statistically significant difference between the tests. However, in the treadmill plus isometric test the work time was shorter and the slope of the treadmill was less than in the treadmill test. The difference was caused partly by non-cardiac factors, namely fatigue of the hand muscles. In routine exercise tests of coronary patients the addition of an isometric to a dynamic load did not give substantially more information than dynamic exercise alone. Nifedipine caused a modest increase of exercise tolerance in all tests, the increase being greatest in the treadmill plus isometric test. The increase in exercise tolerance was seen also in patients receiving beta-blocking agent.","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"19 5","pages":"328-33"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14566874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increase of cardiac output by afterload reduction in patients with severe congestive heart failure using nitroglycerin discs. A double-blind placebo-controlled haemodynamic study. 硝酸甘油椎间盘对严重充血性心力衰竭患者后负荷降低后心排血量的影响。一项双盲安慰剂对照血流动力学研究。

Annals of clinical research Pub Date : 1987-01-01

J Heikkilä, T J Pellinen, P Blake, A McAllister, J Yardley

{"title":"Increase of cardiac output by afterload reduction in patients with severe congestive heart failure using nitroglycerin discs. A double-blind placebo-controlled haemodynamic study.","authors":"J Heikkilä, T J Pellinen, P Blake, A McAllister, J Yardley","doi":"","DOIUrl":"","url":null,"abstract":"In a double-blind crossover study, the haemodynamic effects of nitroglycerin discs were compared with placebo in 9 patients with severe chronic congestive heart failure. Hourly measurements were made throughout 24 hours for the placebo and the active treatment; the first 6 hours were used as a dose titration phase to achieve at least a 5 mmHg decrease in pulmonary arterial diastolic pressure. Active treatment, requiring 30 mg of nitroglycerin in most patients, produced a significant improvement in the cardiac index compared with placebo, as assessed from the end of the dose titration period to the 24th hour. Values determined as baseline, as the average from hour 7 to 24, and at the 24th hour for active discs were 2.3, 2.5 and 2.6 litres/min/m2, whereas for the placebo they were 2.3, 2.2. and 2.2 l/min/m2, respectively. Heart rate remained unchanged during the study, though mean systemic arterial blood pressure and vascular resistance were lower during active treatment. Right atrial and pulmonary arterial pressures did not change. In conclusion, nitroglycerin discs decrease afterload and improve cardiac performance over 24 hours in patients with heart failure.","PeriodicalId":8084,"journal":{"name":"Annals of clinical research","volume":"19 3","pages":"203-7"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14249471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0