脑照射和长期干扰素治疗后的痴呆样，大部分可逆性综合征。

Annals of clinical research Pub Date : 1988-01-01

R Laaksonen, A Niiranen, M Iivanainen, K Mattson, L Holsti, M Färkkilä, K Cantell

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摘要

一名患有小细胞肺癌的老年男性在颅脑照射和长期干扰素(IFN)治疗后出现了一种基本可逆的痴呆样综合征。在接受超过2年的干扰素治疗后，在颅脑照射后2个月开始出现症状。行为障碍并不表明大脑有任何特定的定位。痴呆样行为可能是由于辐照和干扰素的联合作用。

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Dementia-like, largely reversible syndrome after cranial irradiation and prolonged interferon treatment.

An elderly man with small cell lung cancer developed a largely reversible, dementia-like syndrome after cranial irradiation and prolonged treatment with interferon (IFN). The development of the symptoms started 2 months after cranial irradiation following more than 2 years of IFN treatment. The behavioral impairment did not suggest any specific brain localization. The dementia-like behaviour may be due to a combined effect of irradiation and IFN.

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Annals of clinical research

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