Annals of Medicine and Surgery最新文献

{"title":"The Petri dish under the ice: permafrost pathogens and their impact on global healthcare and antibiotic resistance.","authors":"Muhammad M Saleem, Naz Elahi, Roha Athar, Areeba Gul, Mariam Adil, Aayat Ellahi, Haider Kashif, Moussa Hojeij","doi":"10.1097/MS9.0000000000002650","DOIUrl":"10.1097/MS9.0000000000002650","url":null,"abstract":"<p><strong>Background: </strong>A shallow active layer of soil above the permafrost thaws during the summer months which promotes microbial growth and releases previously confined pathogens which result in bacterial epidemics in circumpolar regions. Furthermore, these permafrost sources harbor several antibiotic resistance genes (ARGs) which may disseminate and pose a challenge for pharmacologists worldwide.</p><p><strong>Aims: </strong>The authors examined the potential association between climate change-induced permafrost thawing, and the resulting release of antibiotic-resistant pathogens, as well as the potential impact this can have on global healthcare systems in the long run.</p><p><strong>Methodology: </strong>A cursory abstract screening was done to rule out any articles that did not have to do with viral pathogens caused by melting permafrost. Articles that were not available in English or that our institutions library did not have full-text access were weeded out by a secondary screen.</p><p><strong>Results: </strong>A comprehensive analysis of 13 relevant studies successfully revealed a wide variety of bacterial genera, including <i>Staphylococcus spp.</i>, <i>Pseudomonas spp.</i>, <i>Acinetobacter spp.</i>, and <i>Achromobacter spp.</i>, along with a total of 1043 antibiotic resistance genes (ARGs), with most pertaining to aminoglycosides and beta-lactams, offering resistance via diverse mechanisms such as efflux pumps and enzymatic modifications, within the permafrost isolates. Additionally, mobile genetic elements (MGEs) housing antibiotic resistance genes (ARGs) and virulence factor genes (VFGs), including plasmids and transposons, were also discovered.</p><p><strong>Conclusion: </strong>Permafrost thawing is an underrated healthcare challenge warranting the need for further articles to highlight it alongside concerted efforts for effective mitigation.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"86 12","pages":"7193-7201"},"PeriodicalIF":1.7,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11623853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of emergency nurses and related factors toward geriatric: a cross-sectional study.","authors":"Azam Al-Sadat Asri, Mohammad Reza Yeganeh Rastekanary, Saman Maroufizadeh, Pooyan Ghorbani Vajargah, Samad Karkhah, Nazila Javadi-Pashaki","doi":"10.1097/MS9.0000000000002612","DOIUrl":"https://doi.org/10.1097/MS9.0000000000002612","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the geriatric knowledge of emergency nurses and related factors.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted on nursing students at Guilan University of Medical Sciences in Iran. The objective was to assess the geriatric knowledge of nurses working in the emergency departments of educational and therapeutic centers in Rasht City. The sample was selected through a census sampling method, including all nurses employed in these departments. Data collection was carried out using a three-part questionnaire, which included sections on 'personal and occupational characteristics' and the 'Questionnaire of Awareness about the Facts of Aging (FAQ)'.</p><p><strong>Results: </strong>A total of 190 emergency department nurses participated in this study. The mean age of the participants was 34.41 years (SD=6.37). The mean score for geriatric knowledge among the nurses was 6.58 (SD=2.24). No statistically significant associations were found between geriatric knowledge and the personal or occupational variables of the nurses. Also, the results showed that changes in nurses' geriatric knowledge are explained to a small extent through personal and occupational characteristics.</p><p><strong>Conclusion: </strong>Overall, these results highlight the urgent need for targeted interventions to improve emergency nurses' understanding of geriatric care. Furthermore, given the lack of significant correlations with demographic and occupational variables, future research should investigate additional factors that may influence emergency nurses' knowledge in this area.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"86 11","pages":"6477-6481"},"PeriodicalIF":1.7,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solid-pseudopapillary neoplasm of the pancreas in a 12-year-old female: case report.","authors":"Kundan Kumar Yadav, Krishna Yadav, Binaya Adhikhari, Pratibha Yadav, Prashant Yadav","doi":"10.1097/MS9.0000000000002639","DOIUrl":"10.1097/MS9.0000000000002639","url":null,"abstract":"<p><strong>Introduction and importance: </strong>A solid-pseudopapillary tumor of the pancreas is a rare solid neoplasm. It is an uncommon exocrine tumor that accounts for 1-3% of exocrine pancreatic tumors.</p><p><strong>Case presentation: </strong>The authors have reported two cases of solid-pseudopapillary neoplasm of the pancreas with a median age of 12 years, both in females with abdominal pain.</p><p><strong>Clinical discussion: </strong>Both cases are in females with different treatment modalities. The patient underwent distal pancreatectomy in the first case and enucleation of mass from the distal pancreas in the second case because the size of the tumor is 5 cm and does not involve the bile duct and major pancreatic duct.</p><p><strong>Conclusion: </strong>The authors discussed two cases of solid-pseudopapillary neoplasm of the pancreas both in a 12-year-old female-both the patients presented with abdominal pain. The patient underwent a different treatment. The diagnosis was confirmed by radiological investigation through non-contrast and contrast CT and supported by histopathology findings.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"86 12","pages":"7343-7346"},"PeriodicalIF":1.7,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11623909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of second primary cancers in nodal non-Hodgkin lymphoma patients by primary lymph node location: a retrospective cohort population-based study.","authors":"Ali Hemade, Souheil Hallit","doi":"10.1097/MS9.0000000000002644","DOIUrl":"https://doi.org/10.1097/MS9.0000000000002644","url":null,"abstract":"<p><strong>Background: </strong>Non-Hodgkin lymphoma (NHL) is a diverse group of blood cancers with increasing incidence and survival rates due to advancements in treatment and early detection. However, NHL survivors are at significant risk of developing second primary cancers, which can adversely impact their long-term survival.</p><p><strong>Methods: </strong>This retrospective population-based cohort study utilized data from the Surveillance, Epidemiology, and End Results database, covering 17 geographic areas in the United States from 2000 to 2021. The authors included patients diagnosed with nodal NHL as a first primary cancer and excluded those diagnosed at autopsy or via death certificate only. Standardized Incidence Ratios, Absolute Excess Risks, and Person-Years at Risk were calculated to evaluate the risk of developing SPCs according to the primary lymph node site and stratified by latency periods following the initial NHL diagnosis.</p><p><strong>Results: </strong>The cohort included 54 012 NHL patients. The authors' results showed that for most SPCs, the risk of development was different for different primary NHL lymph node locations. The highest risks were observed for thyroid cancer, acute myeloid leukemia, and Hodgkin lymphoma. Notably, the risk for thyroid cancer was highest in the first year post-diagnosis, while hematological malignancies such as acute myeloid leukemia and Hodgkin lymphoma showed elevated risks in the intermediate and late latency periods.</p><p><strong>Conclusion: </strong>NHL survivors are at an increased risk of developing SPCs, influenced by the primary lymph node site and latency period. These findings highlight the need for tailored surveillance strategies and preventive measures to mitigate the long-term risks of SPCs in NHL survivors. Further research is necessary to elucidate the underlying mechanisms and to develop targeted interventions for this high-risk population.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"86 11","pages":"6455-6464"},"PeriodicalIF":1.7,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543202/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehending unwanted hysterectomies in developing nations: an analysis of women's decision-making processes, underlying causes, and subsequent consequences.","authors":"Shreya Khandelwal","doi":"10.1097/MS9.0000000000002642","DOIUrl":"https://doi.org/10.1097/MS9.0000000000002642","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"86 11","pages":"6404-6406"},"PeriodicalIF":1.7,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel FDA-approved bexagliflozin drug for treating type 2 diabetes mellitus.","authors":"Muhammad M Saleem, Muhammad S Zubair, Soha Abbas, Moussa Hojeij","doi":"10.1097/MS9.0000000000002624","DOIUrl":"https://doi.org/10.1097/MS9.0000000000002624","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"86 11","pages":"6399-6403"},"PeriodicalIF":1.7,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clobetasol propionate for post-cataract surgery pain and inflammation.","authors":"Syeda D Azhar, Nayab Shahid, Aiman Sadiq, Aimen W Khan, Marrium Sultan Dar, Tagwa K Fadlalla Ahmed","doi":"10.1097/MS9.0000000000002619","DOIUrl":"https://doi.org/10.1097/MS9.0000000000002619","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"86 11","pages":"6395-6398"},"PeriodicalIF":1.7,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute renal failure requiring renal replacement therapy secondary to rhabdomyolysis due to rosuvastatin.","authors":"Kundan K Yadav, Bikash K Shah, Srijana K Yadav, Aakash Sherpali, Yesamin Pourkamali, Adesh Kantha, Manoj K Timilsaina","doi":"10.1097/MS9.0000000000002635","DOIUrl":"https://doi.org/10.1097/MS9.0000000000002635","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Statins are the group of medicines that lower the level of low-density lipoprotein cholesterol. One of the life-threatening complications is rhabdomyolysis as the use of these drugs.</p><p><strong>Case presentation: </strong>Here, we report a case of a 69-year-old female who was diagnosed with non-ST elevation myocardial infarction one month and was on regular medication before presentation with generalized weakness and decreased urine output. Proximal muscle weakness was greater than distal muscle on the bilateral lower limb, and power at the hip, knee, and ankle was 3/5 in the bilateral area, with absent reflex at the knee and ankle bilateral area.</p><p><strong>Clinical discussion: </strong>A total of four hemodialysis sessions were performed; the first three sessions were performed at an interval of 24 h, then the last maintenance hemodialysis after 48 h of three sessions. The patient's weakness in the bilateral lower limb returns to normal condition.</p><p><strong>Conclusion: </strong>Physicians need to be aware of the potential of developing severe rhabdomyolysis in patients taking rosuvastatin to prevent morbidity, extended hospital stay, and financial loss.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"86 11","pages":"6832-6834"},"PeriodicalIF":1.7,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety, efficacy, and side effects of sodium fluorescein-aided resection of glioblastoma: a quasi-experimental study.","authors":"Nazmin Ahmed, Md Nazrul Hossain, Raju Ahmed, Md Mahmud Abbasi, Mohammed A Azab, Morshad Alam, Nazia Nusrat Khan, Md Raad Kazi, Nusrat Ghafoor, Nawshin Siraj, Bipin Chaurasia","doi":"10.1097/MS9.0000000000002633","DOIUrl":"https://doi.org/10.1097/MS9.0000000000002633","url":null,"abstract":"<p><strong>Background: </strong>The use of fluorescein sodium (FS) as a surgical adjunct in glioblastoma resection has shown promise in improving tumor visualization and resection outcomes. This study aimed to evaluate the safety, efficacy, and side effects of FS-aided resection in patients with glioblastoma.</p><p><strong>Methods: </strong>This is a prospective, single-center cohort study conducted at Ibrahim Cardiac Hospital and Research Institute from September 2021 to November 2023. Twelve patients with histologically confirmed glioblastoma underwent FS-guided resection. All participants received an intravenous dose of FS (5 mg/kg body weight) ~30 min before surgery. The study follows a quasi-experimental design, focusing on the outcomes of FS-aided surgery without a control group. Patients were selected based on specific inclusion and exclusion criteria, and all surgeries were performed by a single experienced neurosurgeon. The extent of tumor resection was classified as gross total resection (GTR), near-total resection (NTR), or partial resection (PR).</p><p><strong>Results: </strong>Gross total resection (GTR) was achieved in 66.6% of patients, near total resection (NTR) in 16.6%, and subtotal resection (STR) in 16.6%. No significant adverse effects were observed except for a single case of postoperative seizure, which was managed without long-term consequences. All patients showed normal liver and kidney function tests postoperatively. The low-dose FS protocol demonstrated both a high rate of GTR and a favorable safety profile, with only minor, transient side effects such as temporary yellow discoloration of the skin, sclera, and urine. No severe or long-term complications related to FS were observed during the follow-up period, which had a median duration of 13.4 months.</p><p><strong>Conclusion: </strong>FS appears to be a safe and effective aid in glioblastoma resection, achieving high rates of GTR with minimal side effects. The findings suggest that FS, particularly at a low dose, is a viable, cost-effective alternative to other fluorescent markers, especially in settings where resource constraints may limit the use of more expensive options like 5-ALA.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"86 11","pages":"6521-6530"},"PeriodicalIF":1.7,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coexistence of Cecal duplication cyst and Meckel's diverticulum presenting as intestinal obstruction: a rare case report: Retraction.","authors":"","doi":"10.1097/MS9.0000000000002572","DOIUrl":"10.1097/MS9.0000000000002572","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1097/MS9.0000000000002431.].</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"86 10","pages":"6360"},"PeriodicalIF":1.7,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142379968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}