Annals of Medicine and Surgery最新文献

{"title":"Protective eye device for eyelid brachytherapy: Technical report of an innovative personalized method.","authors":"Wijdane El Hawari, Sanaa El Majjaoui, Oussama Bentahar","doi":"10.1097/MS9.0000000000003211","DOIUrl":"10.1097/MS9.0000000000003211","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Carcinoma of the eyelid is a specific anatomical variant of skin cancer, notable for its proximity to the eye. Surgery is the gold standard for managing eyelid cancer, while radiotherapy can serve as an alternative for patients unfit for surgery or as an adjunct treatment. Various devices in maxillofacial prosthodontics are used in conjunction with head and neck radiotherapy to protect the healthy tissues surrounding the irradiation site. These devices are designed by a maxillofacial prosthodontics specialist in collaboration with a radiotherapist/oncologist.</p><p><strong>Case presentation: </strong>This technical report presents an innovative and original method for an eye protection device against radiation. We describe a case involving a 60-year-old woman with basal cell carcinoma of the eyelid, initially treated with surgical excision. High-dose rate brachytherapy was indicated, with a total dose of 40 Gy administered in 8 fractions. Prior to treatment delivery, it was necessary to protect the eyeball from the adverse effects of eyelid BT. We devised a novel device to shield the eyeball and its adnexa.</p><p><strong>Clinical discussion: </strong>This article details the technique for the creation and insertion of this device. To our knowledge, this is the first reported case of an intraocular protective device made with lead. This invention was patented under the reference [MA 56825 B1].</p><p><strong>Conclusion: </strong>The use of a stent designed to shield adjacent tissues from the side effects of radiotherapy is highly advantageous, particularly for critical sites such as the one presented in this clinical case. The success of eye protection in this instance is encouraging and suggests the potential to expand the application of similar devices.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 6","pages":"3847-3852"},"PeriodicalIF":1.7,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare synchronous occurrence: ovarian and renal primary tumors detected simultaneously: a rare case report.","authors":"Mouna Baddoura, Ahmad Idelbi, Reem Salman, Souheb Al-Mahasna","doi":"10.1097/MS9.0000000000003214","DOIUrl":"10.1097/MS9.0000000000003214","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Multiple primary malignancies (MPMs) are separate malignant tumors in the same patient that are not caused by metastasis or recurrence; they represent between 1.84% and 3.9% of all malignancies. Synchronous MPMs, where the tumors are detected at the same time, are even rarer, with a rate of about 0.7%. Moreover, synchronous primary neoplasms involving both the kidneys and ovaries are extremely rare and have been reported in only a few cases in medical literature.</p><p><strong>Presentation: </strong>We present the first case to be reported in Syria as multiple primary tumors of a 62-year-old woman who presented with heaviness in her lower abdomen and right hypochondrium and was found to have synchronous primary tumors, left renal clear cell carcinoma and right ovarian papillary serous cystadenocarcinoma based on computed tomography-scan and histopathology. The patient underwent left radical nephrectomy and resection of the right ovary and will receive adjuvant chemotherapy, with regular follow-up recommended to monitor for any signs of recurrence or metastasis.</p><p><strong>Discussion: </strong>Based on our literature review, the co-occurrence of ovarian tumor with renal cell carcinoma is uncommon. Distinguishing between metastatic tumors and simultaneous primary tumors presents a significant diagnostic challenge. Achieving a precise diagnosis requires the observation of markedly different histologies to confirm the presence of concurrent primary tumors.</p><p><strong>Conclusion: </strong>This case serves as a reminder that when a patient presents with multiple masses, it is important to consider the possibility that they could be separate primary tumors despite their rarity.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 6","pages":"3853-3857"},"PeriodicalIF":1.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of low-level viremia on HIV non-viral load suppression in low and middle-income countries.","authors":"Jackline V Mbishi, Adrian Koola, Haji M Ally, Biruk D Ayalew, Rebecca M Sileshi, Muhidin I Hundisa, Zarin N Rodoshi, Saw W Htoo, Hafidha M Bakari, Zuhura M Ally, Hassan F Fussi, Emilie Ludeman, Taylor Lascko, Celestine A Buyu, Habib O Ramadhani","doi":"10.1097/MS9.0000000000003272","DOIUrl":"10.1097/MS9.0000000000003272","url":null,"abstract":"<p><strong>Background: </strong>The World Health Organization (WHO) defined low-level viremia (LLV) as a viral load (VL) of 51-999 copies/mL, and LLV has been associated with an increased risk of virological failure and drug resistance. Limited information is available from low- and mid-income countries (LMICs), which predominantly use WHO guidelines in HIV program monitoring. We estimated pooled prevalence of LLV, non-viral load suppression (VLS), and association between LLV and non-VLS among people living with HIV in LMICs.</p><p><strong>Materials and methods: </strong>In this systematic review and meta-analysis, databases were searched for articles reporting the association between LLV and non-VLS in LMICs between January 2015 and December 2023. Participants with VL ≤50 copies/mL were considered fully suppressed and those with VL ≥1000 copies/mL were non-suppressed. Using random effects models, we computed the pooled prevalence of LLV, non-VLS, and their corresponding 95% confidence intervals (CIs). We compared pooled prevalence of LLV and non-VLS between children vs adults and between studies done in Africa vs Asia.</p><p><strong>Results: </strong>Sixteen studies with 1 159 317 people living with HIV were analyzed. Overall, pooled prevalence of LLV was 19.7% (95% CI: 15.8-23.6) and that of non-VLS was 8.6% (95% CI: 6.5-10.7). Prevalence of LLV was significantly higher among children compared to adults (25.8% vs 17.2%; <i>P</i> < 0.001) and higher among studies done in Africa compared to those in Asia (22.3% vs 15.6%; <i>P</i> < 0.001). Prevalence of non-VLS was higher among studies involving children compared to adults (17.7% vs 5.6%; <i>P</i> < 0.001), but lower among studies done in Africa compared to Asia 8.3% vs 9.0%; <i>P</i> < 0.001). Overall, LLV increased the risk of non-VLS on a subsequent VL test compared to fully suppressed (RR = 2.6; 95% CI: 2.2-3.1).</p><p><strong>Conclusions: </strong>LLV was associated with an increased risk of non-VLS. Stakeholders should consider reviewing guidelines for the threshold of VLS given that LLV was consistently associated with increased risk of non-VLS across all groups.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 6","pages":"3777-3785"},"PeriodicalIF":1.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current prescription trends in antibiotic prophylaxis: a multinational survey in esthetic plastic surgery.","authors":"Mauricio E Perez Pachon, Alfredo E Hoyos, Tatiana Luna-Pisciotti, Jorge E Benavides, Danna Garcia, Mariana Boras Osorio","doi":"10.1097/MS9.0000000000003274","DOIUrl":"10.1097/MS9.0000000000003274","url":null,"abstract":"<p><strong>Background: </strong>Surgical site infections pose a significant challenge in esthetic surgery, representing one of the most prevalent complications. While research in plastic surgery remains limited, reported rates of SSI range from 0.5% to 32.6%. Although the overall incidence of infections in most esthetic surgeries is low, it carries a significant burden of morbidity, hospital readmissions, and prolonged hospital stays.</p><p><strong>Purpose: </strong>Our study aims to provide evidence-based recommendations regarding the prescription of prophylactic antibiotics for the most common esthetic plastic surgery procedures, based on current trends among plastic surgeons.</p><p><strong>Methods: </strong>An anonymous online survey was conducted among board-certified plastic surgeons to assess antibiotic prophylaxis practices. The survey was distributed via individual links on social media, plastic surgery society platforms, and private surgeon groups. Responses were recorded between February and April 2022 and were available in three different languages: English, Portuguese, and Spanish. The questionnaire covered eight common esthetic procedures, evaluating antibiotic use (prophylactic and non-prophylactic), duration, and type prescribed.</p><p><strong>Results: </strong>Our study analyzed data from 2216 plastic surgery procedures, with 277 respondents answering each of the three questions per procedure. Cephalosporins were the most commonly prescribed antibiotics (73.3%), followed by quinolones (12.9%). Antibiotic therapy exceeded 5 days in 39.6% of cases, while 32.3% reported a 5-day duration. Single-dose prophylaxis was used in only 12% of cases.</p><p><strong>Conclusion: </strong>The rise of multidrug-resistant microorganisms is a growing global concern. Despite established guidelines on antibiotic prophylaxis, misuse among surgeons persists. Our findings highlight the urgent need for stricter antimicrobial stewardship, ensuring that antibiotics are prescribed only when clinically indicated.</p><p><strong>Level of evidence: </strong>III. Type of Study: Cross-Sectional, Observational Survey Study.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 6","pages":"3150-3156"},"PeriodicalIF":1.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of foot reflexology in reducing migraine pain: a randomized controlled trial.","authors":"Marzieh Momennasab, Majid Dejbakht, Hassan Arjmand, Seyed Saeed Najafi, Amin Kordi Yousefinejad","doi":"10.1097/MS9.0000000000003247","DOIUrl":"10.1097/MS9.0000000000003247","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to determine the effect of foot reflexology massage on the intensity, duration, and frequency of pain in patients with migraine headaches.</p><p><strong>Method: </strong>A randomized controlled clinical trial study of three groups was conducted on patients with migraine headaches referred to the neurology department of a specialized clinic in Shiraz, Iran. The patients were randomly divided into three groups. The first, second, and third groups received, respectively: reflexology + drug therapy, sham + drug therapy, and only drug therapy. Changes in the headache daily form, after (T1) and 1 month after interventions (T2) were compared to the beginning of the study (T0).</p><p><strong>Results: </strong>A total of 84 subjects were enrolled in the study. In the end, the study was completed with a study population of 75 subjects. At the end of the study, repeated measures of ANOVA showed that there was a significant difference between the reflexology group and the two groups in terms of mean duration (<i>P</i> = 0.024) and severity (<i>P</i> = 0.043) of migraine headaches. However, the frequency of migraine headaches was not significantly different between the three groups (<i>P</i> = 0.288).</p><p><strong>Conclusions: </strong>In total, this study indicated that reflexology could be effective in reducing the duration and severity of pain in the intervention group. Thus, further studies are suggested to assess the efficacy of this method.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 6","pages":"3221-3228"},"PeriodicalIF":1.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anticoagulant interruption in transcatheter aortic valve implantation (TAVI): a strategy to lower bleeding risks.","authors":"Sana Rasheed, Muhammad Anas, Izere Salomon","doi":"10.1097/MS9.0000000000003285","DOIUrl":"10.1097/MS9.0000000000003285","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 6","pages":"3057-3059"},"PeriodicalIF":1.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare case of schwannomatosis presenting with cauda equina syndrome: a case report.","authors":"Allahdad Khan, Nehan Zahoor, Abdul Ahad Riaz, Humaira Siddique, Anam Malik, Raheel Ahmed, Fnu Poombal, Mohamed Antar","doi":"10.1097/MS9.0000000000003268","DOIUrl":"https://doi.org/10.1097/MS9.0000000000003268","url":null,"abstract":"<p><strong>Background: </strong>Schwannomatosis is a rare disorder characterized by multiple schwannomas without vestibular schwannomas or other features of neurofibromatosis type 2 (NF2). It commonly presents with neuropathic pain, neurological deficits, and soft tissue tumors but rarely leads to cauda equina syndrome, a serious condition requiring urgent intervention.</p><p><strong>Materials and methods: </strong>We report a 28-year-old Pakistani female with progressive back pain, lower limb weakness, sensory deficits, bladder and bowel incontinence, and multiple tender swellings, consistent with cauda equina syndrome. Neurological examination revealed right-sided lower limb weakness. MRI of the brain showed no vestibular schwannomas, while spinal MRI identified a heterogeneously enhancing schwannoma from D11 to L5 with cystic extension into the neural foramina, proximal central canal dilation, and spinal cord compression. Multiple additional schwannomas were detected. Right thigh mass biopsy confirmed schwannoma, showing Antoni A and B regions, Verocay bodies, and S-100 positivity. Genetic testing was not performed due to financial constraints.</p><p><strong>Results: </strong>The patient underwent partial spinal schwannoma resection, leading to spinal decompression and resolution of cauda equina syndrome symptoms. Symptomatic cutaneous schwannomas were excised. Neuropathic pain was managed with pregabalin and NSAIDs. At 6-month follow-up, she showed improved lower limb strength, resolution of incontinence, and no significant tumor regrowth.</p><p><strong>Conclusion: </strong>This case highlights schwannomatosis presenting with cauda equina syndrome, emphasizing the importance of early recognition, spinal decompression, and differentiation from NF2 for optimal management.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 5","pages":"3043-3047"},"PeriodicalIF":1.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidermoid cyst of the tongue: a case report of a rare site of manifestation in a 6-month-old infant.","authors":"Ayham Maidaa, Ayman Sammoun, Muna Al-Din, Doaa Ali, Khaledah Aladwan, Amira Shikh Alkassabin, Mohammad Obada Alsadi, Mohammd Abdulkader","doi":"10.1097/MS9.0000000000003239","DOIUrl":"10.1097/MS9.0000000000003239","url":null,"abstract":"<p><strong>Introduction: </strong>benign cystic growths called epidermoid cysts (ECs) are derived from the germ-native epithelium. They are typically asymptomatic. It is challenging to diagnose these cystic lesions in this region. In one instance, recurrence occurred even following total surgical excision. A precise diagnosis and separation from dermoid are crucial for the best outcome.</p><p><strong>Case presentation: </strong>A six-month-old boy complained of swelling that was getting bigger and was entrenched in his tongue's anterior region. An intraoral examination found a smooth-surfaced, painful cyst that was well-circumscribed. A benign epithelial squamous cyst was discovered following the aspirated fluid's referral to the pathological anatomy division. It was decided to perform surgery. The recommended treatment plan was successful.</p><p><strong>Discussion: </strong>While ECs are commonly located on the face, head, neck, chest, and upper back, instances involving the head and neck region are only 7%, with even fewer affecting the oral cavity, particularly the floor of the mouth.</p><p><strong>Conclusion: </strong>With minimal risk of malignancy and recurrence, successful treatment involves complete surgical excision. Accurate diagnosis and differentiation from dermoid cysts are essential for optimal treatment outcomes.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 6","pages":"3866-3869"},"PeriodicalIF":1.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neutrophils as key regulators of tumor microenvironment in breast cancer: a focus on N1 and N2 polarization.","authors":"Emmanuel Ifeanyi Obeagu, Christian C Ezeala","doi":"10.1097/MS9.0000000000003269","DOIUrl":"10.1097/MS9.0000000000003269","url":null,"abstract":"<p><p>Neutrophils, the most abundant type of white blood cells in the human body, play a vital role in the immune response against infections and tissue injury. However, in the context of cancer, their function becomes more complex and context-dependent. In breast cancer, neutrophils are key players in shaping the tumor microenvironment (TME), a highly dynamic ecosystem where various cell types, extracellular matrix components, and soluble factors interact to influence tumor progression, immune evasion, and metastasis. Neutrophils in the TME are not just passive participants but actively engage in altering tumor biology, either supporting or inhibiting tumor growth depending on their polarization status. Neutrophils exhibit plasticity in their phenotype and function, which can be categorized into two polarized forms: N1 and N2. N1 neutrophils are associated with antitumor responses, promoting immune activation, direct cytotoxicity against tumor cells, and facilitating the clearance of cancerous cells through the release of reactive oxygen species, cytokines, and chemokines. Conversely, N2 neutrophils contribute to tumor progression by fostering an immunosuppressive environment, promoting angiogenesis, enhancing tumor cell migration and invasion, and aiding in the establishment of metastatic niches. This dichotomy of neutrophil polarization plays a crucial role in determining breast cancer progression, metastasis, and response to treatment.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 6","pages":"3509-3522"},"PeriodicalIF":1.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chest drain through utility vs separate incision in single-port video-assisted thoracoscopic lobectomy: a randomized controlled trial.","authors":"Fahmi H Kakamad, Bnar J Hama Amin, Abdulwahid M Salih, Shvan H Mohammed, Hiwa O Baba, Gasha S Ahmed, Soran H Tahir, Rawezh Q Salih, Berun A Abdalla, Dahat H Hussein, Suhaib H Kakamad, Hussein M Hamasalih, Mohammed Subhan Mohammed","doi":"10.1097/MS9.0000000000003233","DOIUrl":"10.1097/MS9.0000000000003233","url":null,"abstract":"<p><strong>Background: </strong>This study explores whether using a separate incision for pleural drainage will yield superior results compared to inserting a chest drain through the utility incision in patients with operable lung cancer undergoing single utility port video-assisted thoracoscopic lobectomy.</p><p><strong>Research question: </strong>Which one is the best?! Inserting the drain through the utility incision or separate incision in a single utility port video-assisted thoracoscopic lobectomy for lung cancer.</p><p><strong>Materials and methods: </strong>This was a randomized, open-label, superiority trial including patients with bronchogenic carcinoma who underwent a single utility port video-assisted thoracoscopic lobectomy over a 32-month period. The primary outcome was wound infections and postoperative pain, while the secondary outcomes were the duration of hospitalization and return to work.</p><p><strong>Results: </strong>The study included 89 patients, and 80 patients completed the trial. The mean age was 65.35 ± 9.47 years, 64 (80%) patients were male, and 69 (86.25%) patients had a 0 ECOG score. Eleven patients (13.75%) had a score of 1. The majority of the patients (35%) were in stage IIIA. There was a small but statistically significant difference in return to work when comparing group A with group B (34 ± 6 vs 31 ± 4 days, <i>P</i> = 0.038). More important were the differences in patients with wound discharge (29 vs 4; <i>P</i> < 0.001) and especially the need for intravenous antibiotic treatment (12 vs 1; <i>P</i> < 0.002). There was only a minimal trend for a decrease in the duration of hospitalization. There was no significant difference in postoperative pain scores.</p><p><strong>Conclusions: </strong>Inserting the chest drain through a separate incision has superior results compared to inserting it through the utility incision in patients with operable lung cancer undergoing single-port video-assisted thoracoscopic lobectomy. However, more studies with a larger sample size are necessary to confirm these results.</p><p><strong>Clinical trial registration: </strong>The research was registered in the Research Registry. The registration number is researchregistry8426. The link is https://www.researchregistry.com/register-now#home/?view_2_search=researchregistry8426&view_2_page=1.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 6","pages":"3215-3220"},"PeriodicalIF":1.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}