Annals of Medicine and Surgery最新文献

{"title":"Before Zaynich becomes routine: a call for reserve-class regulation in South Asia.","authors":"Fnu Zeeshan","doi":"10.1097/MS9.0000000000005500","DOIUrl":"10.1097/MS9.0000000000005500","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 9","pages":"6209-6210"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148928811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small-bowel incarceration and perforation through a hernia defect associated with a pubic fracture: a case report.","authors":"Toru Kume, Takeshi Ohki, Ryosuke Imazato, Machiko Kawaguchi, Takuji Yamada, Shingo Yamashita, Yukiyasu Okamura","doi":"10.1097/MS9.0000000000005583","DOIUrl":"10.1097/MS9.0000000000005583","url":null,"abstract":"<p><strong>Background: </strong>We encountered an extremely rare case of delayed small-bowel incarceration and perforation resulting from herniation through a defect at the site of a pubic fracture.</p><p><strong>Presentation of case: </strong>A 69-year-old man receiving conservative treatment for a pubic fracture presented with abdominal pain approximately 3 months after the initial injury. Contrast-enhanced computed tomography revealed free intraperitoneal air, ascites, and small-bowel dilatation, prompting emergency surgery. Intraoperative findings demonstrated ileal incarceration within a depression at the pubic fracture site, consistent with a Richter-type hernia accompanied by small-bowel perforation. Partial ileal resection with functional end-to-end anastomosis was performed, and the hernial defect was packed with omental tissue. Osteomyelitis observed at the fracture site was treated with antibiotics. The patient was discharged on postoperative day 40.</p><p><strong>Discussion: </strong>Although rare, small-bowel herniation through a pelvic fracture site can result in incarceration and perforation. In this case, hernia repair was challenging because of contamination at the hernia site, which made mesh placement difficult, and the presence of a rigid hernia defect formed by an acquired bony defect, which was difficult to close with sutures. Based on a review of 11 cases reported between 2008 and 2026, including the present case, no standardized repair method has been established to date.</p><p><strong>Conclusion: </strong>Treatment strategies should be individualized and include omental filling, fracture stabilization, and closure or management of the hernia.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 9","pages":"6167-6170"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148928797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circular RNA-based therapeutics in ischemic stroke: emerging targets for neuroprotection.","authors":"Sabeen Tahir, Rejina Chhetri, Janu Chhetri, Marina Kc","doi":"10.1097/MS9.0000000000005619","DOIUrl":"https://doi.org/10.1097/MS9.0000000000005619","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 10","pages":"6916-6917"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the psychology of earthquake victims referred to plastic surgery service after crush injury: a cross-sectional study.","authors":"Ozer Ozmut, Ozden Baz Yagmuroglu, Dogukan Turan, Hasan Murat Ergani, Burak Yasar, Ramazan Erkin Unlu","doi":"10.1097/MS9.0000000000005530","DOIUrl":"https://doi.org/10.1097/MS9.0000000000005530","url":null,"abstract":"<p><strong>Background: </strong>Following the 6 February 2023 earthquake, a significant number of people living in various urban areas suffered crush injuries while trapped under the rubble of collapsed buildings. A significant number of people affected by the earthquake, who were hospitalized for long periods and underwent various surgical interventions for significant injuries, including limb loss, were treated in the plastic surgery department. This study aimed to assess the psychological well-being of patients under our care after the earthquake.</p><p><strong>Methods: </strong>A total of 33 patients (15 males, 18 females) with crush injuries who were referred to our clinic and agreed to undergo psychological examination were included in the study. Our team collaborated with plastic surgeons, psychologists, and allied physicians to carry out interventions, assessments, and interviews. Demographic, injury, psychological, and social support information was collected for evaluation after hospitalization.</p><p><strong>Results: </strong>The study found that, in terms of personal factors, aggression and depression levels were significantly higher in men than in women. As for age, verbal aggression level (<i>r</i> = -0.405), depression level (<i>r</i> = -0.369), and numerous psychotic symptoms (<i>r</i> = -0.439) were inversely correlated with age. When social factors were investigated, verbal aggression (<i>r</i> = 0.376) and self-confidence (<i>r</i> = 0.432) were directly proportional to higher education levels. Depression and psychosis levels were found to be statistically significantly higher in patients with lower incomes (<i>P</i> < 0.05). Patients who lost their next of kin were found to be statistically significantly affected by acute stress (<i>P</i> = 0.003). As for medical factors, several psychotic symptoms were inversely correlated with larger areas of injury (<i>r</i> = -0.385). Increasing numbers of debridement sessions were also found to be directly correlated with anxiety symptoms (<i>r</i> = 0.345).</p><p><strong>Conclusions: </strong>The surgical team responsible for providing medical care to patients after an earthquake should be aware of the psychological state of the individuals they treat. Providing psychological and social support by the surgical team in the early stages after the earthquake, particularly for young patients, patients with low incomes, and those who have lost family members, may be considered a potentially beneficial component of multidisciplinary post-disaster care.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 10","pages":"6330-6336"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: Double, double toil and trouble: a case of combined esophageal and gastrointestinal duplication cysts in infancy and a review of the literature: erratum.","authors":"","doi":"10.1097/MS9.0000000000005628","DOIUrl":"10.1097/MS9.0000000000005628","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1097/MS9.0000000000005192.].</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 9","pages":"6219"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe iron-deficiency anemia and recurrent mucosal bleeding revealing Glanzmann thrombasthenia in a young adult: a case report.","authors":"Manasa Kuppireddy, Dikshitha Bai R","doi":"10.1097/MS9.0000000000005629","DOIUrl":"https://doi.org/10.1097/MS9.0000000000005629","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Glanzmann thrombasthenia is a rare inherited platelet function disorder characterized by defective platelet aggregation and mucocutaneous bleeding. Although it typically presents in childhood, delayed diagnosis in adulthood is uncommon and poses diagnostic challenges, particularly when routine coagulation parameters are normal.</p><p><strong>Case presentation: </strong>We report a young adult male who presented with recurrent gingival bleeding and severe iron-deficiency anemia without a prior history of childhood bleeding. Routine coagulation studies and platelet counts were normal. Platelet aggregation studies demonstrated absent aggregation to all agonists except ristocetin, confirming the diagnosis of Glanzmann thrombasthenia. The patient was managed with supportive care and transfusion as required.</p><p><strong>Clinical discussion: </strong>This case highlights the importance of considering inherited platelet function disorders in adults with unexplained mucocutaneous bleeding despite normal initial laboratory investigations. Platelet aggregation studies remain the diagnostic gold standard and are essential to avoid delayed diagnosis and inappropriate management.</p><p><strong>Conclusion: </strong>Glanzmann thrombasthenia can rarely present in adulthood and should be considered in patients with persistent isolated mucocutaneous bleeding. Early recognition allows appropriate counselling, bleeding prevention strategies, and optimized transfusion planning.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 10","pages":"6818-6821"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Borderline resectable pancreatic ductal adenocarcinoma: a narrative review.","authors":"Rupesh Thapa Chhetri, Krisha Maharjan","doi":"10.1097/MS9.0000000000005565","DOIUrl":"https://doi.org/10.1097/MS9.0000000000005565","url":null,"abstract":"<p><p>Borderline resectable (BR) pancreatic ductal adenocarcinoma (PDAC) is a well-recognized entity with specific characteristics. Previously considered inoperable, these tumors are now increasingly resectable due to advances in neoadjuvant chemotherapy. This review synthesizes current knowledge on diagnostic, therapeutic, and management approaches for pancreatic ductal adenocarcinoma, especially for BR disease. It covers the definition, criteria, and surgical management, along with various clinical challenges in the diagnosis of borderline disease. Neoadjuvant therapy is the treatment of choice before surgery, but there are still limited data on the selection of optimal therapy and on the early identification of non-responders. Multidetector computed tomography, along with CA19-9 and positron emission tomography, are being used to evaluate resectability after neoadjuvant therapy. Pancreatic resection for PDAC is one of the most complex procedures in abdominal surgery due to the technical and oncological challenges associated with its aggressive growth. Despite these options, management remains challenging.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 10","pages":"6654-6661"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in echocardiography for congenital heart defects (CHDs): a literature review.","authors":"Muhammad Abdullah Humayun, Carla Jammal, Anita Zhou, Ahila Ali, Hamza Maqbool, Aoun Zaib Khan, Amna Zaheer, Jamuna Shreshtha, Anum Akbar","doi":"10.1097/MS9.0000000000005273","DOIUrl":"https://doi.org/10.1097/MS9.0000000000005273","url":null,"abstract":"<p><p>Congenital heart defects (CHDs) are the most prevalent congenital condition globally, affecting approximately 1% of live births and contributing to significant morbidity and mortality. While advancements in diagnostic imaging have improved early detection and management, CHDs remain a leading cause of infant mortality, particularly in low- and middle-income regions. Echocardiography has evolved as a cornerstone in CHD diagnosis, with traditional modalities such as 2D echocardiography, M-mode, and Doppler imaging providing essential structural and hemodynamic assessments. However, these conventional approaches have limitations in visualizing complex congenital anomalies. The emergence of advanced echocardiographic techniques, including three-dimensional echocardiography, fetal echocardiography, speckle tracking echocardiography (STE), and stress echocardiography (SE), has significantly enhanced diagnostic accuracy, preoperative planning, and long-term monitoring. Furthermore, recent innovations in artificial intelligence (AI), deep learning, digital signal processing, and contrast-enhanced echocardiography are revolutionizing the field by automating image analysis, improving image quality, and enabling predictive modeling for CHD prognosis. This review critically compares traditional and advanced echocardiographic modalities, evaluating their respective strengths, limitations, and impact on early CHD detection. Additionally, it explores emerging AI-driven technologies and their potential to optimize echocardiographic workflows, reduce diagnostic variability, and enhance patient outcomes. By synthesizing current evidence, this review aims to provide clinicians, researchers, and healthcare policymakers with insights into the evolving role of echocardiography in CHD diagnosis and management.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 10","pages":"6529-6542"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case report of Rasmussen's aneurysm in multidrug-resistant tuberculosis from Nepal.","authors":"Aashish Lamichhane, Apil Pokhrel, Sadish Sharma, Bidya Adhikari","doi":"10.1097/MS9.0000000000005612","DOIUrl":"https://doi.org/10.1097/MS9.0000000000005612","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Rasmussen's aneurysm is a radiological finding and an uncommon cause of hemoptysis in pulmonary tuberculosis. It results from weakening of pulmonary arterial wall due to inflammation adjacent to a tuberculous cavity.</p><p><strong>Case presentation: </strong>We report a case of 52-year-old male diagnosed with pulmonary tuberculosis, who presented with recurrent hemoptysis despite being on anti-tubercular therapy. Bacteriological examination using line probe assay revealed resistance to Rifampicin and Isoniazid, confirming multidrug resistant tuberculosis (MDR-TB). CT pulmonary angiogram (CT-PA) was performed, which demonstrated a dilated vascular channel adjacent to a cavity in the left upper lobe of the lung, suggestive of Rasmussen's aneurysm. It was managed with trans-arterial embolization, followed by initiation of second-line regimen for MDR-TB.</p><p><strong>Clinical discussion: </strong>As Rasmussen's aneurysm is rare, it is often overlooked when a TB case presents with massive hemoptysis. If left untreated, it could be fatal. This case highlights the utility of prompt investigation and intervention to manage the complication and prevent further deterioration.</p><p><strong>Conclusion: </strong>Rasmussen's aneurysm is a rare cause of hemoptysis, especially in cavitary or MDR-TB. Early diagnosis with CT-PA and management with endovascular approach could be life-saving.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 10","pages":"6802-6806"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute mesenteric ischemia caused by adhesive-band-induced mesenteric artery compression with secondary ileal volvulus and internal hernia: a rare case report.","authors":"Bahaa Ibrahim AbuRahmeh, Mohamad A Banat, Ahmad G Hammouri, Ahmad J A Abuarqoub, Yara Al Najajreh, Sulaiman Naji Fakhouri","doi":"10.1097/MS9.0000000000005615","DOIUrl":"https://doi.org/10.1097/MS9.0000000000005615","url":null,"abstract":"<p><strong>Introduction: </strong>Acute mesenteric ischemia (AMI) is a surgical emergency caused by inadequate blood flow through the mesenteric vessels, resulting in intestinal ischemia and eventual gangrene of the bowel wall. The condition may result from arterial thrombosis, embolism, mesenteric venous thrombosis, or non-occlusive systemic hypoperfusion.</p><p><strong>Case presentation: </strong>We report a rare case of AMI in a 73-year-old female with a significant past surgical history of transabdominal hysterectomy with bilateral salpingo-oopherectomy. She presented with sudden, severe abdominal pain that was disproportionate to the relatively benign examination; she was unresponsive to multiple analgesics, raising suspicion of an underlying surgical pathology. Computed tomography angiography (CTA) showed ileal-like volvulus with vascular compromise, and features of internal hernia, prompting emergent surgery, which confirmed adhesive-band-induced mesenteric compression with the other findings. At first glance, the surgeon gave a chance to bowel; a second-look operation after 48 hours insisted on the inevitable need for resecting the involved segment of bowel.</p><p><strong>Discussion: </strong>Patients with AMI typically present with sudden-onset abdominal pain that is disproportionate to the physical examination findings (soft abdomen with mild or absent tenderness on palpation). Laboratory investigations may support the diagnosis but lack sufficient sensitivity and specificity for definitive diagnosis. CTA is the imaging modality of choice for establishing the diagnosis.</p><p><strong>Conclusion: </strong>This case highlights a rare mechanism of AMI. It emphasizes the importance of taking a good history and doing a good examination, and highlights the importance of early diagnosis and management of critical surgical conditions such as AMI.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 10","pages":"6812-6817"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}