Annual review of nutrition最新文献_第9页

The Microbiota and Malnutrition: Impact of Nutritional Status During Early Life. 微生物群与营养不良：生命早期营养状况的影响。

IF 8.9 2区医学

Annual review of nutrition Pub Date : 2019-08-21 DOI: 10.1146/annurev-nutr-082117-051716

C. Gómez-Gallego, C. Gómez-Gallego, I. García-Mantrana, C. Martínez-Costa, S. Salminen, E. Isolauri, E. Isolauri, M. Collado, M. Collado

{"title":"The Microbiota and Malnutrition: Impact of Nutritional Status During Early Life.","authors":"C. Gómez-Gallego, C. Gómez-Gallego, I. García-Mantrana, C. Martínez-Costa, S. Salminen, E. Isolauri, E. Isolauri, M. Collado, M. Collado","doi":"10.1146/annurev-nutr-082117-051716","DOIUrl":"https://doi.org/10.1146/annurev-nutr-082117-051716","url":null,"abstract":"According to the developmental origins of health and disease hypothesis, our health is determined by events experienced in utero and during early infancy. Indeed, both our prenatal and postnatal nutrition conditions have an impact on the initial architecture and activity of our microbiota. Recent evidence has underlined the importance of the composition of the early gut microbiota in relation to malnutrition, whether it be undernutrition or overnutrition, that is, in terms of both stunted and overweight development. It remains unclear how early microbial contact is linked to the risk of disease, as well as whether alterations in the microbiome underlie the pathogenesis of malnutrition or are merely the end result of it, which indicates that thequestion of causality must urgently be answered. This review provides information on the complex interaction between the microbiota and nutrition during the first 1,000 days of life, taking into account the impact of both undernutrition and overnutrition on the microbiota and on infants' health outcomes in the short- and long-term.","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"39 1","pages":"267-290"},"PeriodicalIF":8.9,"publicationDate":"2019-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-nutr-082117-051716","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46991791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Copper Transport and Disease: What Can We Learn from Organoids? 铜的运输与疾病:我们能从类器官中学到什么?

IF 8.9 2区医学

Annual review of nutrition Pub Date : 2019-08-21 Epub Date: 2019-05-31 DOI: 10.1146/annurev-nutr-082018-124242

Hannah Pierson, Haojun Yang, Svetlana Lutsenko

{"title":"Copper Transport and Disease: What Can We Learn from Organoids?","authors":"Hannah Pierson, Haojun Yang, Svetlana Lutsenko","doi":"10.1146/annurev-nutr-082018-124242","DOIUrl":"https://doi.org/10.1146/annurev-nutr-082018-124242","url":null,"abstract":"Many metals have biological functions and play important roles in human health. Copper (Cu) is an essential metal that supports normal cellular physiology. Significant research efforts have focused on identifying the molecules and pathways involved in dietary Cu uptake in the digestive tract. The lack of an adequate in vitro model for assessing Cu transport processes in the gut has led to contradictory data and gaps in our understanding of the mechanisms involved in dietary Cu acquisition. The recent development of organoid technology has provided a tractable model system for assessing the detailed mechanistic processes involved in Cu utilization and transport in the context of nutrition. Enteroid (intestinal epithelial organoid)-based studies have identified new links between intestinal Cu metabolism and dietary fat processing. Evidence for a metabolic coupling between the dietary uptake of Cu and uptake of fat (which were previously thought to be independent) is a new and exciting finding that highlights the utility of these three-dimensional primary culture systems. This review has three goals: (a) to critically discuss the roles of key Cu transport enzymes in dietary Cu uptake; (b) to assess the use, utility, and limitations of organoid technology in research into nutritional Cu transport and Cu-based diseases; and (c) to highlight emerging connections between nutritional Cu homeostasis and fat metabolism.","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"39 ","pages":"75-94"},"PeriodicalIF":8.9,"publicationDate":"2019-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-nutr-082018-124242","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37295549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 38

Time-Restricted Eating to Prevent and Manage Chronic Metabolic Diseases. 限时饮食预防和控制慢性代谢疾病。

IF 8.9 2区医学

Annual review of nutrition Pub Date : 2019-08-21 Epub Date: 2019-06-10 DOI: 10.1146/annurev-nutr-082018-124320

Amandine Chaix, Emily N C Manoogian, Girish C Melkani, Satchidananda Panda

{"title":"Time-Restricted Eating to Prevent and Manage Chronic Metabolic Diseases.","authors":"Amandine Chaix, Emily N C Manoogian, Girish C Melkani, Satchidananda Panda","doi":"10.1146/annurev-nutr-082018-124320","DOIUrl":"https://doi.org/10.1146/annurev-nutr-082018-124320","url":null,"abstract":"Molecular clocks are present in almost every cell to anticipate daily recurring and predictable changes, such as rhythmic nutrient availability, and to adapt cellular functions accordingly. At the same time, nutrient-sensing pathways can respond to acute nutrient imbalance and modulate and orient metabolism so cells can adapt optimally to a declining or increasing availability of nutrients. Organismal circadian rhythms are coordinated by behavioral rhythms such as activity-rest and feeding-fasting cycles to temporally orchestrate a sequence of physiological processes to optimize metabolism. Basic research in circadian rhythms has largely focused on the functioning of the self-sustaining molecular circadian oscillator, while research in nutrition science has yielded insights into physiological responses to caloric deprivation or to specific macronutrients. Integration of these two fields into actionable new concepts in the timing of food intake has led to the emerging practice of time-restricted eating. In this paradigm, daily caloric intake is restricted to a consistent window of 8-12 h. This paradigm has pervasive benefits on multiple organ systems.","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"39 ","pages":"291-315"},"PeriodicalIF":8.9,"publicationDate":"2019-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-nutr-082018-124320","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37318233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 199

The Economics of Taxes on Sugar-Sweetened Beverages: A Review of the Effects on Prices, Sales, Cross-Border Shopping, and Consumption. 含糖饮料税收的经济学:对价格、销售、跨境购物和消费影响的综述。

IF 8.9 2区医学

Annual review of nutrition Pub Date : 2019-08-21 Epub Date: 2019-05-22 DOI: 10.1146/annurev-nutr-082018-124603

John Cawley, Anne Marie Thow, Katherine Wen, David Frisvold

{"title":"The Economics of Taxes on Sugar-Sweetened Beverages: A Review of the Effects on Prices, Sales, Cross-Border Shopping, and Consumption.","authors":"John Cawley, Anne Marie Thow, Katherine Wen, David Frisvold","doi":"10.1146/annurev-nutr-082018-124603","DOIUrl":"https://doi.org/10.1146/annurev-nutr-082018-124603","url":null,"abstract":"During the past decade, dozens of countries, regions, and cities have enacted taxes on sugar-sweetened beverages (SSBs). They have been primarily motivated by a desire to raise prices, reduce sales and consumption, improve population health, and raise revenue. This review outlines the economic rationale for SSB taxes and illustrates their predicted effects. It reviews the research on the effects of these taxes on retail prices, sales, cross-border shopping, consumption, and product availability. The evidence indicates that the amount by which taxes increase retail prices (also called the pass-through of the tax) varies by jurisdiction, ranging from less than 50% to 100% of the tax. Sales tend to decrease significantly in the taxing jurisdiction, although this seems to be partly offset by residents increasingly shopping outside of the taxing jurisdiction (i.e., engaging in cross-border shopping).Overall, taxes lower consumption of the taxed beverages by adults, although not for all types of beverages or all groups of consumers. We conclude with suggestions for improving the design of such taxes and directions for future research.","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"39 ","pages":"317-338"},"PeriodicalIF":8.9,"publicationDate":"2019-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-nutr-082018-124603","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37267358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 145

Dietary Fuels in Athletic Performance. 运动表现中的膳食燃料。

IF 8.9 2区医学

Annual review of nutrition Pub Date : 2019-08-21 Epub Date: 2019-05-28 DOI: 10.1146/annurev-nutr-082018-124337

Andreas Mæchel Fritzen, Anne-Marie Lundsgaard, Bente Kiens

引用次数: 19

Mitochondrial DNA Mutation, Diseases, and Nutrient-Regulated Mitophagy. 线粒体DNA突变、疾病和营养调节的线粒体自噬。

IF 8.9 2区医学

Annual review of nutrition Pub Date : 2019-08-21 DOI: 10.1146/annurev-nutr-082018-124643

Xuan Yang, Ruoyu Zhang, K. Nakahira, Zhenglong Gu

{"title":"Mitochondrial DNA Mutation, Diseases, and Nutrient-Regulated Mitophagy.","authors":"Xuan Yang, Ruoyu Zhang, K. Nakahira, Zhenglong Gu","doi":"10.1146/annurev-nutr-082018-124643","DOIUrl":"https://doi.org/10.1146/annurev-nutr-082018-124643","url":null,"abstract":"A wide spectrum of human diseases, including cancer, neurodegenerative diseases, and metabolic disorders, have been shown to be associated with mitochondrial dysfunction through multiple molecular mechanisms. Mitochondria are particularly susceptible to nutrient deficiencies, and nutritional intervention is an essential way to maintain mitochondrial homeostasis. Recent advances in genetic manipulation and next-generation sequencing reveal the crucial roles of mitochondrial DNA (mtDNA) in various pathophysiological conditions. Mitophagy, a term coined to describe autophagy that targets dysfunctional mitochondria, has emerged as an important cellular process to maintain mitochondrial homeostasis and has been shown to be regulated by various nutrients and nutritional stresses. Given the high prevalence of mtDNA mutations in humans and their impact on mitochondrial function, it is important to investigate the mechanisms that regulate mtDNA mutation. Here, we discuss mitochondrial genetics and mtDNA mutations and their implications for human diseases. We also examine the role of mitophagy as a therapeutic target, highlighting how nutrients may eliminate mtDNA mutations through mitophagy.","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"39 1","pages":"201-226"},"PeriodicalIF":8.9,"publicationDate":"2019-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-nutr-082018-124643","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44703763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

FADS1 and FADS2 Polymorphisms Modulate Fatty Acid Metabolism and Dietary Impact on Health. FADS1和FADS2多态性调节脂肪酸代谢和饮食对健康的影响。

IF 8.9 2区医学

Annual review of nutrition Pub Date : 2019-08-21 DOI: 10.1146/annurev-nutr-082018-124250

Berthold Koletzko, Eva Reischl, Conny Tanjung, Ines Gonzalez-Casanova, Usha Ramakrishnan, Suzanne Meldrum, Karen Simmer, Joachim Heinrich, Hans Demmelmair

{"title":"FADS1 and FADS2 Polymorphisms Modulate Fatty Acid Metabolism and Dietary Impact on Health.","authors":"Berthold Koletzko, Eva Reischl, Conny Tanjung, Ines Gonzalez-Casanova, Usha Ramakrishnan, Suzanne Meldrum, Karen Simmer, Joachim Heinrich, Hans Demmelmair","doi":"10.1146/annurev-nutr-082018-124250","DOIUrl":"10.1146/annurev-nutr-082018-124250","url":null,"abstract":"Variants in the FADS gene cluster modify the activity of polyunsaturated fatty acid (PUFA) desaturation and the lipid composition in human blood and tissue. FADS variants have been associated with plasma lipid concentrations, risk of cardiovascular diseases, overweight, eczema, pregnancy outcomes, and cognitive function. Studies on variations in the FADS genecluster provided some of the first examples for marked gene-diet interactions in modulating complex phenotypes, such as eczema, asthma, and cognition. Genotype distribution differs markedly among ethnicities, apparently reflecting an evolutionary advantage of genotypes enabling active long-chain PUFA synthesis when the introduction of agriculture provided diets rich in linoleic acid but with little arachidonic and eicosapentaenoic acids. Discovering differential effects of PUFA supply that depend on variation of FADS genotypes could open new opportunities for developing precision nutrition strategies based either on an individual's genotype or on genotype distributions in specific populations.","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"39 1","pages":"21-44"},"PeriodicalIF":8.9,"publicationDate":"2019-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42032270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maintaining Balance. 保持平衡。

IF 8.9 2区医学

Annual review of nutrition Pub Date : 2019-08-21 Epub Date: 2019-04-12 DOI: 10.1146/annurev-nutr-082018-124634

Janet C King

{"title":"Maintaining Balance.","authors":"Janet C King","doi":"10.1146/annurev-nutr-082018-124634","DOIUrl":"https://doi.org/10.1146/annurev-nutr-082018-124634","url":null,"abstract":"Writing this biography forced me to look back over my career as a scientist, teacher, wife, and mother. To my surprise, a lifelong theme emerged that I was unaware of, that is, the role of maintaining balance between work and family, science and teaching, mentorship and administration, and personal values and challenges. My primary mentor, Dr. Doris Calloway, demonstrated the importance of maintaining balance. My interest in nutrition started as a preschooler living on a farm where I learned firsthand the importance of balancing the expense of providing good nutrition to the livestock with potential income. In our small high school, I became acquainted with the fascinating field of chemistry, but found it critical to balance that interest with a politically correct field of study for a woman in the early 1960s. I chose dietetics for its strong roots in chemistry. As a US Army dietitian, I learned firsthand how to conduct metabolic studies and knew, immediately, that I had to balance that interest with future opportunities feasible for a dietitian. I chose the University of California, Berkeley, for my PhD because it needed to train dietitians in research to balance an emerging need to offer undergraduates a practicum in dietetics. My subsequent faculty appointment there enabled me to develop novel isotopic approaches for studying zinc and prenatal nutrition, and balance my research with teaching and administrative responsibilities. During the next 40 years, my work as a Berkeley professor led to appointments at the Western Human Nutrition Research Center and Children's Hospital Oakland Research Institute, while balancing my responsibilities as a wife and a mother to my two sons. Balance is defined as a condition in which different elements are equal or in the correct proportions. It is extremely satisfying to look back and see evidence of successfully balancing the disparate elements of my career.","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"39 ","pages":"1-19"},"PeriodicalIF":8.9,"publicationDate":"2019-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-nutr-082018-124634","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37152216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Personalized Dietary Management of Overweight and Obesity Based on Measures of Insulin and Glucose. 基于胰岛素和血糖测量的超重和肥胖症个性化饮食管理。

IF 12.6 2区医学

Annual review of nutrition Pub Date : 2018-08-21 Epub Date: 2018-06-01 DOI: 10.1146/annurev-nutr-082117-051606

Mads F Hjorth, Yishai Zohar, James O Hill, Arne Astrup

引用次数: 0

Brain Nutrition: A Life Span Approach. 大脑营养:一个生命周期的方法。

IF 8.9 2区医学

Annual review of nutrition Pub Date : 2018-08-21 Epub Date: 2018-06-01 DOI: 10.1146/annurev-nutr-082117-051652

Manu S Goyal, Lora L Iannotti, Marcus E Raichle

引用次数: 32