Annual review of nutrition最新文献

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Standardized Reference Diets for Zebrafish: Addressing Nutritional Control in Experimental Methodology. 斑马鱼标准化参考日粮:在实验方法中解决营养控制问题。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2021-10-11 Epub Date: 2021-07-16 DOI: 10.1146/annurev-nutr-120420-034809
Stephen A Watts, Louis R D'Abramo
{"title":"Standardized Reference Diets for Zebrafish: Addressing Nutritional Control in Experimental Methodology.","authors":"Stephen A Watts,&nbsp;Louis R D'Abramo","doi":"10.1146/annurev-nutr-120420-034809","DOIUrl":"https://doi.org/10.1146/annurev-nutr-120420-034809","url":null,"abstract":"<p><p>The ideal of experimental methodology in animal research is the reduction or elimination of environmental variables or consistency in their application. In lab animals, diet has been recognized as a very influential response variable. Reproducibility in research using rodents required the development of a unique diet of consistent ingredient and nutrient composition to allow for cross-comparisons of lab results, spatially and temporally. These diets are commonly referred to as standard reference diets (SRDs). The established validity of published nutritional requirements combined with the cooperation of commercial partners led to species-specific reference diets commonly used by the research community. During the last several decades, zebrafish (<i>Danio rerio</i>) have become a widespread alternative animal model, but specific knowledge of their nutrition is lacking. We present a short-term approach for developing an SRD for zebrafish, similar to that eventually attained for rodents over decades. Imminent development of an open-formulation, commercially produced SRD for zebrafish will notably advance translational biomedical science.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":" ","pages":"511-527"},"PeriodicalIF":8.9,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582320/pdf/nihms-1746134.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39190746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
The Roles of Cytoplasmic Lipid Droplets in Modulating Intestinal Uptake of Dietary Fat. 细胞质脂滴在调节肠道脂肪吸收中的作用。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2021-10-11 Epub Date: 2021-07-20 DOI: 10.1146/annurev-nutr-110320-013657
Alyssa S Zembroski, Changting Xiao, Kimberly K Buhman
{"title":"The Roles of Cytoplasmic Lipid Droplets in Modulating Intestinal Uptake of Dietary Fat.","authors":"Alyssa S Zembroski,&nbsp;Changting Xiao,&nbsp;Kimberly K Buhman","doi":"10.1146/annurev-nutr-110320-013657","DOIUrl":"https://doi.org/10.1146/annurev-nutr-110320-013657","url":null,"abstract":"<p><p>Dietary fat absorption is required for health but also contributes to hyperlipidemia and metabolic disease when dysregulated. One step in the process of dietary fat absorption is the formation of cytoplasmic lipid droplets (CLDs) in small intestinal enterocytes; these CLDs serve as dynamic triacylglycerol storage organelles that influence the rate at which dietary fat is absorbed. Recent studies have uncovered novel factors regulating enterocyte CLD metabolism that in turn influence the absorption of dietary fat. These include peroxisome proliferator-activated receptor α activation, compartmentalization of different lipid pools, the gut microbiome, liver X receptor and farnesoid X receptor activation, obesity, and physiological factors stimulating CLD mobilization. Understanding how enterocyte CLD metabolism is regulated is key in modulating the absorption of dietary fat in the prevention of hyperlipidemia and its associated metabolic disorders.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":" ","pages":"79-104"},"PeriodicalIF":8.9,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39201534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Cardiometabolic Benefits of Intermittent Fasting. 间歇性禁食对心脏代谢的益处。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2021-10-11 DOI: 10.1146/annurev-nutr-052020-041327
Krista A Varady, Sofia Cienfuegos, Mark Ezpeleta, Kelsey Gabel
{"title":"Cardiometabolic Benefits of Intermittent Fasting.","authors":"Krista A Varady,&nbsp;Sofia Cienfuegos,&nbsp;Mark Ezpeleta,&nbsp;Kelsey Gabel","doi":"10.1146/annurev-nutr-052020-041327","DOIUrl":"https://doi.org/10.1146/annurev-nutr-052020-041327","url":null,"abstract":"<p><p>This review aims to summarize the effects of intermittent fasting on markers of cardiometabolic health in humans. All forms of fasting reviewed here-alternate-day fasting (ADF), the 5:2 diet, and time-restricted eating (TRE)-produced mild to moderate weight loss (1-8% from baseline) and consistent reductions in energy intake (10-30% from baseline). These regimens may benefit cardiometabolic health by decreasing blood pressure, insulin resistance, and oxidative stress. Low-density lipoprotein cholesterol and triglyceride levels are also lowered, but findings are variable. Other health benefits, such as improved appetite regulation and favorable changes in the diversity of the gut microbiome, have also been demonstrated, but evidence for these effects is limited. Intermittent fasting is generally safe and does not result in energy level disturbances or increased disordered eating behaviors. In summary, intermittent fasting is a safe diet therapy that can produce clinically significant weight loss (>5%) and improve several markers of metabolic health in individuals with obesity.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":" ","pages":"333-361"},"PeriodicalIF":8.9,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39507965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 46
Genetics of Sleep and Insights into Its Relationship with Obesity. 睡眠的遗传学及其与肥胖的关系。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2021-10-11 Epub Date: 2021-06-08 DOI: 10.1146/annurev-nutr-082018-124258
Hassan S Dashti, José M Ordovás
{"title":"Genetics of Sleep and Insights into Its Relationship with Obesity.","authors":"Hassan S Dashti,&nbsp;José M Ordovás","doi":"10.1146/annurev-nutr-082018-124258","DOIUrl":"https://doi.org/10.1146/annurev-nutr-082018-124258","url":null,"abstract":"<p><p>Considerable recent advancements in elucidating the genetic architecture of sleep traits and sleep disorders may provide insight into the relationship between sleep and obesity. Despite the involvement of the circadian clock in sleep and metabolism, few shared genes, including <i>FTO</i>, were implicated in genome-wide association studies (GWASs) of sleep and obesity. Polygenic scores composed of signals from GWASs of sleep traits show largely null associations with obesity, suggesting lead variants are unique to sleep. Modest genome-wide genetic correlations are observed between many sleep traits and obesity and are largest for snoring. Notably, U-shaped positive genetic correlations with body mass index (BMI) exist for both short and long sleep durations. Findings from Mendelian randomization suggest robust causal effects of insomnia on higher BMI and, conversely, of higher BMI on snoring and daytime sleepiness. In addition, bidirectional effects between sleep duration and daytime napping with obesity may also exist. Limited gene-sleep interaction studies suggest that achieving favorable sleep, as part of a healthy lifestyle, may attenuate genetic predisposition to obesity,but whether these improvements produce clinically meaningful reductions in obesity risk remains unclear. Investigations of the genetic link between sleep and obesity for sleep disorders other than insomnia and in populations of non-European ancestry are currently limited.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":" ","pages":"223-252"},"PeriodicalIF":8.9,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39090494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Is Food Addictive? A Review of the Science. 食物会上瘾吗?科学综述。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2021-10-11 Epub Date: 2021-06-21 DOI: 10.1146/annurev-nutr-110420-111710
Ashley N Gearhardt, Erica M Schulte
{"title":"Is Food Addictive? A Review of the Science.","authors":"Ashley N Gearhardt,&nbsp;Erica M Schulte","doi":"10.1146/annurev-nutr-110420-111710","DOIUrl":"https://doi.org/10.1146/annurev-nutr-110420-111710","url":null,"abstract":"<p><p>As ultraprocessed foods (i.e., foods composed of mostly cheap industrial sources of dietary energy and nutrients plus additives) have become more abundant in our food supply, rates of obesity and diet-related disease have increased simultaneously. Food addiction has emerged as a phenotype of significant empirical interest within the past decade, conceptualized most commonly as a substance-based addiction to ultraprocessed foods. We detail (<i>a</i>) how approaches used to understand substance-use disorders may be applicable for operationalizing food addiction, (<i>b</i>) evidence for the reinforcing potential of ingredients in ultraprocessed foods that may drive compulsive consumptions, (<i>c</i>) the utility of conceptualizing food addiction as a substance-use disorder versus a behavioral addiction, and (<i>d</i>) clinical and policy implications that may follow if ultraprocessed foods exhibit an addictive potential. Broadly, the existing literature suggests biological and behavioral parallels between food addiction and substance addictions, with ultraprocessed foods high in both added fat and refined carbohydrates being most implicated in addictive-like eating. Future research priorities are also discussed, including the need for longitudinal studies and the potential negative impact of addictive ultraprocessed foods on children.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":" ","pages":"387-410"},"PeriodicalIF":8.9,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39252187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 65
Celebrating 40 Years of the Annual Review of Nutrition. 庆祝《营养年鉴》创刊40周年。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2021-10-11 DOI: 10.1146/annurev-nu-41-080221-100001
Rudi Balling, Patrick J Stover
{"title":"Celebrating 40 Years of the Annual Review of Nutrition.","authors":"Rudi Balling,&nbsp;Patrick J Stover","doi":"10.1146/annurev-nu-41-080221-100001","DOIUrl":"https://doi.org/10.1146/annurev-nu-41-080221-100001","url":null,"abstract":"","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":" ","pages":"v-vi"},"PeriodicalIF":8.9,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39507963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional Qualities and Enhancement of Edible Insects. 食用昆虫的营养品质及改良。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2021-10-11 Epub Date: 2021-06-29 DOI: 10.1146/annurev-nutr-041520-010856
Arnold van Huis, Birgit Rumpold, Cassandra Maya, Nanna Roos
{"title":"Nutritional Qualities and Enhancement of Edible Insects.","authors":"Arnold van Huis,&nbsp;Birgit Rumpold,&nbsp;Cassandra Maya,&nbsp;Nanna Roos","doi":"10.1146/annurev-nutr-041520-010856","DOIUrl":"https://doi.org/10.1146/annurev-nutr-041520-010856","url":null,"abstract":"<p><p>Over the last decade, the urgency to find alternative and sustainable protein sources has prompted an exponential increase in the interest in insects as a human food source. Edible insects contribute suitable amounts of energy and protein, fatty acids, and micronutrients to the human diet. Nutritional values of insects can be manipulated to meet specific needs. Edible insects in food-insecure countries can contribute to improving diets and preventing undernutrition. Bioactive compounds in insects may reduce health risks. Food safety risks are low and mainly relate to those of allergenicity. Strategies to overcome barriers to the consumption of insect products include emphasizing their sustainability, increasing their tastiness, and developing the ability to disguise insects in familiar products. A new sector of insects as food and feed is emerging. Major challenges include legislation, lowering prices by automation and cheap substrates, developing insect products that appeal to consumers, and exploring the health benefits.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":" ","pages":"551-576"},"PeriodicalIF":8.9,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39038222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
Adverse Effects of Medications on Micronutrient Status: From Evidence to Guidelines. 药物对微量营养素状态的不良影响:从证据到指南。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2021-10-11 Epub Date: 2021-06-10 DOI: 10.1146/annurev-nutr-120420-023854
Michael S Daniels, Brian I Park, Diane L McKay
{"title":"Adverse Effects of Medications on Micronutrient Status: From Evidence to Guidelines.","authors":"Michael S Daniels,&nbsp;Brian I Park,&nbsp;Diane L McKay","doi":"10.1146/annurev-nutr-120420-023854","DOIUrl":"https://doi.org/10.1146/annurev-nutr-120420-023854","url":null,"abstract":"<p><p>Recent dietary reference intake workshops focusing on nutrient requirements in chronic disease populations have called attention to the potential adverse effects of chronic medication use on micronutrient status. Although this topic is mostly ill defined in the literature, several noteworthy drug-nutrient interactions (DNIs) are of clinical and public health significance. The purpose of this narrative review is to showcase classic examples of DNIs and their impact on micronutrient status, including those related to antidiabetic, anticoagulant, antihypertensive, antirheumatic, and gastric acid-suppressing medications. Purported DNIs related to other drug families, while relevant and worthy of discussion, are not included. Unlike previous publications, this review is primarily focused on DNIs that have sufficient evidence supporting their inclusion in US Food and Drug Administration labeling materials and/or professional guidelines. While the evidence is compelling, more high-quality research is needed to establish clear and quantitative relationships between chronic medication use and micronutrient status.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":" ","pages":"411-431"},"PeriodicalIF":8.9,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39081096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Microbial Flavonoid Metabolism: A Cardiometabolic Disease Perspective. 微生物类黄酮代谢:心脏代谢疾病的视角。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2021-10-11 DOI: 10.1146/annurev-nutr-120420-030424
Lucas J Osborn, Jan Claesen, J Mark Brown
{"title":"Microbial Flavonoid Metabolism: A Cardiometabolic Disease Perspective.","authors":"Lucas J Osborn,&nbsp;Jan Claesen,&nbsp;J Mark Brown","doi":"10.1146/annurev-nutr-120420-030424","DOIUrl":"https://doi.org/10.1146/annurev-nutr-120420-030424","url":null,"abstract":"<p><p>Cardiometabolic disease (CMD) is a leading cause of death worldwide and encompasses the inflammatory metabolic disorders of obesity, type 2 diabetes mellitus, nonalcoholic fatty liver disease, and cardiovascular disease. Flavonoids are polyphenolic plant metabolites that are abundantly present in fruits and vegetables and have biologically relevant protective effects in a number of cardiometabolic disorders. Several epidemiological studies underscored a negative association between dietary flavonoid consumption and the propensity to develop CMD. Recent studies elucidated the contribution of the gut microbiota in metabolizing dietary intake as it relates to CMD. Importantly, the biological efficacy of flavonoids in humans and animal models alike is linked to the gut microbial community. Herein, we discuss the opportunities and challenges of leveraging flavonoid intake as a potential strategy to prevent and treat CMD in a gut microbe-dependent manner, with special emphasis on flavonoid-derived microbial metabolites.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":" ","pages":"433-454"},"PeriodicalIF":8.9,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39507962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Novel Approaches for Omega-3 Fatty Acid Therapeutics: Chronic Versus Acute Administration to Protect Heart, Brain, and Spinal Cord. Omega-3脂肪酸治疗的新方法:慢性与急性给药以保护心脏、大脑和脊髓。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2020-09-23 DOI: 10.1146/annurev-nutr-082018-124539
Hylde Zirpoli, Chuchun L Chang, Yvon A Carpentier, Adina T Michael-Titus, Vadim S Ten, Richard J Deckelbaum
{"title":"Novel Approaches for Omega-3 Fatty Acid Therapeutics: Chronic Versus Acute Administration to Protect Heart, Brain, and Spinal Cord.","authors":"Hylde Zirpoli,&nbsp;Chuchun L Chang,&nbsp;Yvon A Carpentier,&nbsp;Adina T Michael-Titus,&nbsp;Vadim S Ten,&nbsp;Richard J Deckelbaum","doi":"10.1146/annurev-nutr-082018-124539","DOIUrl":"https://doi.org/10.1146/annurev-nutr-082018-124539","url":null,"abstract":"<p><p>This article reviews novel approaches for omega-3 fatty acid (FA) therapeutics and the linked molecular mechanisms in cardiovascular and central nervous system (CNS) diseases. In vitro and in vivo research studies indicate that omega-3 FAs affect synergic mechanisms that include modulation of cell membrane fluidity, regulation of intracellular signaling pathways, and production of bioactive mediators. We compare how chronic and acute treatments with omega-3 FAs differentially trigger pathways of protection in heart, brain, and spinal cord injuries. We also summarize recent omega-3 FA randomized clinical trials and meta-analyses and discuss possible reasons for controversial results, with suggestions on improving the study design for future clinical trials. Acute treatment with omega-3 FAs offers a novel approach for preserving cardiac and neurological functions, and the combinations of acute treatment with chronic administration of omega-3 FAs might represent an additional therapeutic strategy for ameliorating adverse cardiovascular and CNS outcomes.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"40 ","pages":"161-187"},"PeriodicalIF":8.9,"publicationDate":"2020-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-nutr-082018-124539","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38410221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
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