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Annual review of nutrition最新文献

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Nutritional Mechanisms of Cancer Cachexia. 癌症乏力的营养机制。
IF 12.6 2区 医学
Annual review of nutrition Pub Date : 2024-08-01 DOI: 10.1146/annurev-nutr-062122-015646
Stephanie L E Compton, Steven B Heymsfield, Justin C Brown
{"title":"Nutritional Mechanisms of Cancer Cachexia.","authors":"Stephanie L E Compton, Steven B Heymsfield, Justin C Brown","doi":"10.1146/annurev-nutr-062122-015646","DOIUrl":"https://doi.org/10.1146/annurev-nutr-062122-015646","url":null,"abstract":"<p><p>Cancer cachexia is a complex systemic wasting syndrome. Nutritional mechanisms that span energy intake, nutrient metabolism, body composition, and energy balance may be impacted by, and may contribute to, the development of cachexia. To date, clinical management of cachexia remains elusive. Leaning on discoveries and novel methodologies from other fields of research may bolster new breakthroughs that improve nutritional management and clinical outcomes. Characteristics that compare and contrast cachexia and obesity may reveal opportunities for cachexia research to adopt methodology from the well-established field of obesity research. This review outlines the known nutritional mechanisms and gaps in the knowledge surrounding cancer cachexia. In parallel, we present how obesity may be a different side of the same coin and how obesity research has tackled similar research questions. We present insights into how cachexia research may utilize nutritional methodology to expand our understanding of cachexia to improve definitions and clinical care in future directions for the field.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"44 1","pages":"77-98"},"PeriodicalIF":12.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutrition, Other Environmental Influences, and Genetics in the Determination of Human Stature. 营养、其他环境影响和遗传在人类身材决定中的作用。
IF 12.6 2区 医学
Annual review of nutrition Pub Date : 2024-08-01 Epub Date: 2024-08-12 DOI: 10.1146/annurev-nutr-061121-091112
Julian C Lui, Amanda C Palmer, Parul Christian
{"title":"Nutrition, Other Environmental Influences, and Genetics in the Determination of Human Stature.","authors":"Julian C Lui, Amanda C Palmer, Parul Christian","doi":"10.1146/annurev-nutr-061121-091112","DOIUrl":"10.1146/annurev-nutr-061121-091112","url":null,"abstract":"<p><p>Linear growth during three distinct stages of life determines attained stature in adulthood: namely, in utero, early postnatal life, and puberty and the adolescent period. Individual host factors, genetics, and the environment, including nutrition, influence attained human stature. Each period of physical growth has its specific biological and environmental considerations. Recent epidemiologic investigations reveal a strong influence of prenatal factors on linear size at birth that in turn influence the postnatal growth trajectory. Although average population height changes have been documented in high-income regions, stature as a complex human trait is not well understood or easily modified. This review summarizes the biology of linear growth and its major drivers, including nutrition from a life-course perspective, the genetics of programmed growth patterns or height, and gene-environment interactions that determine human stature in toto over the life span. Implications for public health interventions and knowledge gaps are discussed.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":" ","pages":"205-229"},"PeriodicalIF":12.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140955901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies. 含糖饮料与不良人体健康结果：观察性研究元分析综述》。
IF 12.6 2区 医学
Annual review of nutrition Pub Date : 2024-08-01 DOI: 10.1146/annurev-nutr-062322-020650
Melissa M Lane, Nikolaj Travica, Elizabeth Gamage, Skye Marshall, Gina L Trakman, Claire Young, Scott B Teasdale, Thusharika Dissanayaka, Samantha L Dawson, Rebecca Orr, Felice N Jacka, Adrienne O'Neil, Mark Lawrence, Phillip Baker, Casey M Rebholz, Shutong Du, Wolfgang Marx
{"title":"Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies.","authors":"Melissa M Lane, Nikolaj Travica, Elizabeth Gamage, Skye Marshall, Gina L Trakman, Claire Young, Scott B Teasdale, Thusharika Dissanayaka, Samantha L Dawson, Rebecca Orr, Felice N Jacka, Adrienne O'Neil, Mark Lawrence, Phillip Baker, Casey M Rebholz, Shutong Du, Wolfgang Marx","doi":"10.1146/annurev-nutr-062322-020650","DOIUrl":"10.1146/annurev-nutr-062322-020650","url":null,"abstract":"<p><p>Our aim was to conduct an umbrella review of evidence from meta-analyses of observational studies investigating the link between sugar-sweetened beverage consumption and human health outcomes. Using predefined evidence classification criteria, we evaluated evidence from 47 meta-analyses encompassing 22,055,269 individuals. Overall, 79% of these analyses indicated direct associations between greater sugar-sweetened beverage consumption and higher risks of adverse health outcomes. Convincing evidence (class I) supported direct associations between sugar-sweetened beverage consumption and risks of depression, cardiovascular disease, nephrolithiasis, type 2 diabetes mellitus, and higher uric acid concentrations. Highly suggestive evidence (class II) supported associations with risks of nonalcoholic fatty liver disease and dental caries. Out of the remaining 40 meta-analyses, 29 were graded as suggestive or weak in the strength of evidence (classes III and IV), and 11 showed no evidence (class V). These findings inform and provide support for population-based and public health strategies aimed at reducing sugary drink consumption for improved health.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"44 1","pages":"383-404"},"PeriodicalIF":12.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biosynthesis and Metabolism of ApoB-Containing Lipoproteins 含载脂蛋白 B 脂蛋白的生物合成与代谢
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2024-04-18 DOI: 10.1146/annurev-nutr-062222-020716
Jan Borén, Marja-Riitta Taskinen, Chris J. Packard
{"title":"Biosynthesis and Metabolism of ApoB-Containing Lipoproteins","authors":"Jan Borén, Marja-Riitta Taskinen, Chris J. Packard","doi":"10.1146/annurev-nutr-062222-020716","DOIUrl":"https://doi.org/10.1146/annurev-nutr-062222-020716","url":null,"abstract":"Recent advances in human genetics, together with a substantial body of epidemiological, preclinical and clinical trial evidence, strongly support a causal relationship between triglyceride-rich lipoproteins (TRLs) and atherosclerotic cardiovascular disease. Consequently, the secretion and metabolism of TRLs have a significant impact on cardiovascular health. This knowledge underscores the importance of understanding the molecular mechanisms and regulation of very-low-density lipoprotein (VLDL) and chylomicron biogenesis. Fortunately, there has been a resurgence of interest in the intracellular assembly, trafficking, degradation, and secretion of VLDL, leading to many ground-breaking molecular insights. Furthermore, the identification of molecular control mechanisms related to triglyceride metabolism has greatly advanced our understanding of the complex metabolism of TRLs. In this review, we explore recent advances in the assembly, secretion, and metabolism of TRLs. We also discuss available treatment strategies for hypertriglyceridemia.","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"52 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140628327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unhealthy Food and Beverage Marketing to Children in the Digital Age: Global Research and Policy Challenges and Priorities 数字时代向儿童推销不健康食品和饮料：全球研究和政策挑战与优先事项
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2024-04-18 DOI: 10.1146/annurev-nutr-062322-014102
Emma Boyland, Kathryn Backholer, Monique Potvin Kent, Marie A. Bragg, Fiona Sing, Tilakavati Karupaiah, Bridget Kelly
{"title":"Unhealthy Food and Beverage Marketing to Children in the Digital Age: Global Research and Policy Challenges and Priorities","authors":"Emma Boyland, Kathryn Backholer, Monique Potvin Kent, Marie A. Bragg, Fiona Sing, Tilakavati Karupaiah, Bridget Kelly","doi":"10.1146/annurev-nutr-062322-014102","DOIUrl":"https://doi.org/10.1146/annurev-nutr-062322-014102","url":null,"abstract":"Food and nonalcoholic beverage marketing is implicated in poor diet and obesity in children. The rapid growth and proliferation of digital marketing has resulted in dramatic changes to advertising practices and children's exposure. The constantly evolving and data-driven nature of digital food marketing presents substantial challenges for researchers seeking to quantify the impact on children and for policymakers tasked with designing and implementing restrictive policies. We outline the latest evidence on children's experience of the contemporary digital food marketing ecosystem, conceptual frameworks guiding digital food marketing research, the impact of digital food marketing on dietary outcomes, and the methods used to determine impact, and we consider the key research and policy challenges and priorities for the field. Recent methodological and policy developments represent opportunities to apply novel and innovative solutions to address this complex issue, which could drive meaningful improvements in children's dietary health.","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"127 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140627997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Black American Nutrition Scholar and Advocate: My Journey 美国黑人营养学者和倡导者：我的旅程
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2024-04-11 DOI: 10.1146/annurev-nutr-062322-030901
Shiriki K. Kumanyika
{"title":"A Black American Nutrition Scholar and Advocate: My Journey","authors":"Shiriki K. Kumanyika","doi":"10.1146/annurev-nutr-062322-030901","DOIUrl":"https://doi.org/10.1146/annurev-nutr-062322-030901","url":null,"abstract":"I started my journey as a nutrition scholar in 1974 when I began PhD studies at Cornell University. My journey has been rich with opportunity. I engaged in research on diet-related risks for cardiovascular diseases, diabetes, and cancer, partly motivated by my strong commitment to addressing health disparities affecting Black Americans. Obesity became my major focus and would eventually involve both US and global lenses. This focus was also linked to other dietary intake issues and health disparities and drew on knowledge I had gained in my prior study and practice of social work. I positioned myself as a bridge builder across nutrition, epidemiology, and public health, advocating for certain new ways of thinking and acting in these spheres and in the academy itself. Life skills honed during my formative years living within racially segregated contexts have been critical to any successes I have achieved.","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"57 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140559997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nonalcoholic Fatty Liver Disease and Omega-3 Fatty Acids: Mechanisms and Clinical Use. 非酒精性脂肪性肝病和Omega-3脂肪酸:机制和临床应用。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2023-08-21 DOI: 10.1146/annurev-nutr-061021-030223
Melinda H Spooner, Donald B Jump
{"title":"Nonalcoholic Fatty Liver Disease and Omega-3 Fatty Acids: Mechanisms and Clinical Use.","authors":"Melinda H Spooner,&nbsp;Donald B Jump","doi":"10.1146/annurev-nutr-061021-030223","DOIUrl":"https://doi.org/10.1146/annurev-nutr-061021-030223","url":null,"abstract":"<p><p>Nonalcoholic fatty liver disease (NAFLD) is the most common chronic fatty liver disease worldwide, particularly in obese and type 2 diabetic individuals. Currently, there are no therapies for NAFLD that have been approved by the US Food and Drug Administration. Herein, we examine the rationale for using ω3 polyunsaturated fatty acids (PUFAs) in NAFLD therapy. This focus is based on the finding that NAFLD severity is associated with a reduction of hepatic C<sub>20-22</sub> ω3 PUFAs. Because C<sub>20-22</sub> ω3 PUFAs are pleiotropic regulators of cell function, loss of C<sub>20-22</sub> ω3 PUFAs has the potential to significantly impact hepatic function. We describe NAFLD prevalence and pathophysiology as well as current NAFLD therapies. We also present evidence from clinical and preclinical studies that evaluated the capacity of C<sub>20-22</sub> ω3 PUFAs to treat NAFLD. Given the clinical and preclinical evidence, dietary C<sub>20-22</sub> ω3 PUFA supplementation has the potential to decrease human NAFLD severity by reducing hepatosteatosis and liver injury.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"43 ","pages":"199-223"},"PeriodicalIF":8.9,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10400311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Nutrition in the Age of Precision and Systems Biology. 精确和系统生物学时代的营养。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2023-08-21 DOI: 10.1146/annurev-nu-43-062723-100001
Rudi Balling, Patrick J Stover
{"title":"Nutrition in the Age of Precision and Systems Biology.","authors":"Rudi Balling,&nbsp;Patrick J Stover","doi":"10.1146/annurev-nu-43-062723-100001","DOIUrl":"https://doi.org/10.1146/annurev-nu-43-062723-100001","url":null,"abstract":"","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"43 ","pages":"v-vi"},"PeriodicalIF":8.9,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10413354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteocalcin: A Multifaceted Bone-Derived Hormone. 骨钙素一种多方面的骨源性激素
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2023-08-21 DOI: 10.1146/annurev-nutr-061121-091348
Gerard Karsenty
{"title":"Osteocalcin: A Multifaceted Bone-Derived Hormone.","authors":"Gerard Karsenty","doi":"10.1146/annurev-nutr-061121-091348","DOIUrl":"10.1146/annurev-nutr-061121-091348","url":null,"abstract":"<p><p>Together, loss- and gain-of-function experiments have identified the bone-derived secreted molecule osteocalcin as a hormone with a broad reach in rodents and primates. Following its binding to one of three receptors, osteocalcin exerts a profound influence on various aspects of energy metabolism as well as steroidogenesis, neurotransmitter biosynthesis and thereby male fertility, electrolyte homeostasis, cognition, the acute stress response, and exercise capacity. Although this review focuses mostly on the regulation of energy metabolism by osteocalcin, it also touches on its other functions. Lastly, it proposes what could be a common theme between the functions of osteocalcin and between these functions and the structural functions of bone.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"43 ","pages":"55-71"},"PeriodicalIF":8.9,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11059196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10413355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal Amino Acid Transport and Metabolic Health. 肠道氨基酸转运与代谢健康。
IF 8.9 2区 医学
Annual review of nutrition Pub Date : 2023-08-21 DOI: 10.1146/annurev-nutr-061121-094344
Stefan Bröer
{"title":"Intestinal Amino Acid Transport and Metabolic Health.","authors":"Stefan Bröer","doi":"10.1146/annurev-nutr-061121-094344","DOIUrl":"https://doi.org/10.1146/annurev-nutr-061121-094344","url":null,"abstract":"<p><p>Amino acids derived from protein digestion are important nutrients for the growth and maintenance of organisms. Approximately half of the 20 proteinogenic amino acids can be synthesized by mammalian organisms, while the other half are essential and must be acquired from the nutrition. Absorption of amino acids is mediated by a set of amino acid transporters together with transport of di- and tripeptides. They provide amino acids for systemic needs and for enterocyte metabolism. Absorption is largely complete at the end of the small intestine. The large intestine mediates the uptake of amino acids derived from bacterial metabolism and endogenous sources. Lack of amino acid transporters and peptide transporter delays the absorption of amino acids and changes sensing and usage of amino acids by the intestine. This can affect metabolic health through amino acid restriction, sensing of amino acids, and production of antimicrobial peptides.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":"43 ","pages":"73-99"},"PeriodicalIF":8.9,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10418754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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