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[Determination of aminoglycoside antibiotics in biological fluids]. 生物体液中氨基糖苷类抗生素的测定
Antibiotiki Pub Date : 1984-09-01
V L Karpov
{"title":"[Determination of aminoglycoside antibiotics in biological fluids].","authors":"V L Karpov","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 9","pages":"695-703"},"PeriodicalIF":0.0,"publicationDate":"1984-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17449840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Use of adsorbents for optimizing the process of isolating nisin from the culture broth]. [利用吸附剂优化从培养液中分离乳酸链球菌素的工艺]。
Antibiotiki Pub Date : 1984-09-01
I P Baranova, V A Grushina, N S Egorov
{"title":"[Use of adsorbents for optimizing the process of isolating nisin from the culture broth].","authors":"I P Baranova,&nbsp;V A Grushina,&nbsp;N S Egorov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of the study on optimization of the process of nisin isolation from the cultural liquid are presented. Different adsorbents, streptococcal cells, medium solid particles (biomass fermentalysates) and silica gel, were used for antibiotic adsorption.</p>","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 9","pages":"643-5"},"PeriodicalIF":0.0,"publicationDate":"1984-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17498387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Experimental study of lincomycin ointment and gel]. 林可霉素软膏凝胶的实验研究。
Antibiotiki Pub Date : 1984-09-01
E Z Kagan, N I Sinitsyna, V I Danilova, E K Berezina, V V Berezhinskaia
{"title":"[Experimental study of lincomycin ointment and gel].","authors":"E Z Kagan,&nbsp;N I Sinitsyna,&nbsp;V I Danilova,&nbsp;E K Berezina,&nbsp;V V Berezhinskaia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The pharmacokinetics and safety of the lincomycin ointment and gel were studied. It was shown that diffusion of lincomycin through the skin was satisfactory. Investigation of their general toxicity and organotropic properties revealed neither irritating effect nor changes in the internal organs associated with the toxic effect of the drugs. On the basis of the data on the stability of the lincomycin ointment and gel obtained on their storage the lincomycin ointment was recommended for industrial production.</p>","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 9","pages":"645-8"},"PeriodicalIF":0.0,"publicationDate":"1984-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17566029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Isoniazid concentrations in the blood, resected lung tissue and the gallbladder bed in relation to the method of administration to pulmonary tuberculosis patients with stomach and liver diseases]. [血液、切除肺组织和胆囊床中异烟肼浓度与肺结核合并胃和肝脏疾病患者给药方法的关系]。
Antibiotiki Pub Date : 1984-09-01
E E Androsov, V A Vinokurov, G F Garvalinskiĭ, V R Karita, M B Pogrebinskiĭ
{"title":"[Isoniazid concentrations in the blood, resected lung tissue and the gallbladder bed in relation to the method of administration to pulmonary tuberculosis patients with stomach and liver diseases].","authors":"E E Androsov,&nbsp;V A Vinokurov,&nbsp;G F Garvalinskiĭ,&nbsp;V R Karita,&nbsp;M B Pogrebinskiĭ","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The advisability of isoniazid administration in the form of ultrasonic aerosols in the treatment of patients with pulmonary tuberculosis and diseases of the gastrointestinal tract is shown.</p>","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 9","pages":"671-3"},"PeriodicalIF":0.0,"publicationDate":"1984-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17566032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Antitumor antibiotics in the treatment of nephroblastomas in children]. [抗肿瘤抗生素治疗儿童肾母细胞瘤]。
Antibiotiki Pub Date : 1984-09-01
G Kh Badalian, V I Lebedev, L I Gusev, B I Dolgushin
{"title":"[Antitumor antibiotics in the treatment of nephroblastomas in children].","authors":"G Kh Badalian,&nbsp;V I Lebedev,&nbsp;L I Gusev,&nbsp;B I Dolgushin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of the chemotherapy of 20 children with nephroblastoma are analysed. The patients were treated according to the following scheme: vincristine in a dose of 0.05 mg kg bw once a week on the 1st, 8th, 15th and 22nd days, dactinomycin in a dose of 15 micrograms/kg once a day for 3 days on the 1st, 2nd and 3rd days of adriamycin in a dose of 30-40 mg/m2 on the 15th day of the treatment course. The postoperative chemotherapy was started 10 days after the operation. It was performed in 4 courses with intervals of 3 weeks. The efficacy of the treatment was estimated with angiography, echography and computer-aided tomography. The above scheme proved to be efficient in the treatment of the children with nephroblastoma. Reliable control of the tumor size during the preoperative treatment was shown to be possible.</p>","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 9","pages":"676-8"},"PeriodicalIF":0.0,"publicationDate":"1984-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17162755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pathomorphological picture of the testes of mice administered antitumor antibiotics and their comparative evaluation]. [使用抗肿瘤抗生素的小鼠睾丸病理形态学图及其比较评价]。
Antibiotiki Pub Date : 1984-09-01
N V Semenov
{"title":"[Pathomorphological picture of the testes of mice administered antitumor antibiotics and their comparative evaluation].","authors":"N V Semenov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A single administration of the LD50 of bruneomycin, carminomycin, rubomycin or olivomycin and the use of the antibiotics for 10 days in a dose 2 times higher than the therapeutic one and amounting to 10 per cent of the LD50 induced dystrophic and destructive changes in the sexual glands of mice. The changes in the testis were more pronounced after the single use of the antibiotics. Recovery processes were observed in the testis beginning from the middle of the third week after the use of carminomycin and rubomycin and from the end of the second week after the use of olivomycin. Bruneomycin was an exception: the pronounced destructive changes in the sexual glands after its single or repeated use persisted within the observation period.</p>","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 9","pages":"666-71"},"PeriodicalIF":0.0,"publicationDate":"1984-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17566031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Antibacterial preparations against nonsporulating anaerobic bacteria]. [抗非孢子厌氧细菌的抗菌制剂]。
Antibiotiki Pub Date : 1984-08-01
I I Oleĭnik, B D Bychenko, T G Robustova, L P Zhdanov
{"title":"[Antibacterial preparations against nonsporulating anaerobic bacteria].","authors":"I I Oleĭnik,&nbsp;B D Bychenko,&nbsp;T G Robustova,&nbsp;L P Zhdanov","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 8","pages":"619-28"},"PeriodicalIF":0.0,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17445287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[7-chloro-7-deoxylincomycin (clindamycin)]. [7-chloro-7-deoxylincomycin(克林霉素)]。
Antibiotiki Pub Date : 1984-08-01
M S Poliak, L G Miasnikova
{"title":"[7-chloro-7-deoxylincomycin (clindamycin)].","authors":"M S Poliak,&nbsp;L G Miasnikova","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 8","pages":"628-35"},"PeriodicalIF":0.0,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17445288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Use of semisynthetic penicillins and cephalosporins in trauma and orthopedic patients]. 半合成青霉素和头孢菌素在创伤和骨科患者中的应用
Antibiotiki Pub Date : 1984-08-01
V M Mel'nikova, A I Gladshteĭn
{"title":"[Use of semisynthetic penicillins and cephalosporins in trauma and orthopedic patients].","authors":"V M Mel'nikova,&nbsp;A I Gladshteĭn","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The data on the use and clinical efficacy of semisynthetic penicillins and cephalosporins in the treatment of the traumatologic and orthopedic patients are summarized.</p>","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 8","pages":"614-5"},"PeriodicalIF":0.0,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17543613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of Streptomyces spheroides proteinases on the mechanism of antibacterial protection in an experiment]. [球链霉菌蛋白酶对抗菌保护机制的实验研究]。
Antibiotiki Pub Date : 1984-08-01
N S Egorov, E A Oleĭnikova, G B Anoshkina, N S Landau
{"title":"[Effect of Streptomyces spheroides proteinases on the mechanism of antibacterial protection in an experiment].","authors":"N S Egorov,&nbsp;E A Oleĭnikova,&nbsp;G B Anoshkina,&nbsp;N S Landau","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of Streptomyces spheroides proteinases on the process and character of the local reaction to intraperitoneal infection of mice with E. coli was studied experimentally. It was shown that administration of the proteinases promoted a decrease in the dissemination of the abdominal cavity and a more rapid elimination of the microorganisms from the infection foci. The proteinases potentiated the macrophagal component of the local reaction by accelerating migration of the macrophages and increasing their phagocytic activity and the activity of the lysosomal enzymes. Proteinases gave rise to a pronounced activation of the neutrophils, an increase in the phagocytic capacity of the young forms and a change in intracellular enzymes. It was demonstrated that proteinases changed interrelation between the cell elements in the infection foci, the character of interaction of the quantitative and functional parameters of the local reaction and interrelationship between the phagocytic activity and the enzymatic balance of the cells. They increased the effect of the macrophages on migration and the functional state of the neutrophiles.</p>","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 8","pages":"595-600"},"PeriodicalIF":0.0,"publicationDate":"1984-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17445286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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