林可霉素软膏凝胶的实验研究。

Antibiotiki Pub Date : 1984-09-01

E Z Kagan, N I Sinitsyna, V I Danilova, E K Berezina, V V Berezhinskaia

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引用次数: 0

摘要

研究了林可霉素软膏和凝胶的药动学及安全性。结果表明，林可霉素在皮肤中的扩散是令人满意的。对它们的一般毒性和嗜器官性质的调查显示，既没有刺激作用，也没有与药物毒性作用相关的内脏改变。根据对林可霉素软膏和凝胶贮存稳定性的研究，推荐林可霉素软膏用于工业生产。

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[Experimental study of lincomycin ointment and gel].

The pharmacokinetics and safety of the lincomycin ointment and gel were studied. It was shown that diffusion of lincomycin through the skin was satisfactory. Investigation of their general toxicity and organotropic properties revealed neither irritating effect nor changes in the internal organs associated with the toxic effect of the drugs. On the basis of the data on the stability of the lincomycin ointment and gel obtained on their storage the lincomycin ointment was recommended for industrial production.

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Antibiotiki

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