Antibiotiki最新文献_第4页

[Effect of levorin on the intracellular pool of free amino acids in Ehrlich ascites carcinoma cells]. [左旋素对埃利希腹水癌细胞胞内游离氨基酸池的影响]。

Antibiotiki Pub Date : 1984-10-01

I S Gorozhankina, E B Lishnevskaia

引用次数: 0

[Use of prodigiozan for increasing the effectiveness of the antibiotic therapy of dysentery in children]. [使用prodigiozan提高儿童痢疾抗生素治疗的有效性]。

Antibiotiki Pub Date : 1984-10-01

I A Vereshchagin, O D Zhuravleva

引用次数: 0

[Directed isolation of gram-negative asporogenous bacteria from natural substrates]. [从天然底物中定向分离革兰氏阴性菌种]。

Antibiotiki Pub Date : 1984-10-01

L P Ivanitskaia, E M Singal, L E Bodunkova, L N Ostanina, M V Baturina

引用次数: 0

[Variability of Vibrio cholerae as affected by subbacteriostatic concentrations of antibiotics]. [抗生素亚抑菌浓度对霍乱弧菌变异的影响]。

Antibiotiki Pub Date : 1984-10-01

I T Andrusenko, E A Ved'mina, N I Givental', N A Pasternak, I K Aleksandrova

引用次数: 0

[Lysozyme in the feeding of premature infants with mixed pathology]. [混合病理早产儿喂养中的溶菌酶]。

Antibiotiki Pub Date : 1984-10-01

A M Bol'shakova, E G Shcherbakova, S D Ivanova, M M Medvedeva, T P Zhuravleva

{"title":"[Lysozyme in the feeding of premature infants with mixed pathology].","authors":"A M Bol'shakova, E G Shcherbakova, S D Ivanova, M M Medvedeva, T P Zhuravleva","doi":"","DOIUrl":"","url":null,"abstract":"Lysozyme is an important component of the breast milk. In the gastrointestinal tract of infants it performs the function of a local protective factor. The efficacy of the use of milk enriched with lysozyme was studied in feeding of 64 premature infants suffering from concomitant diseases. This clinical and laboratory study was performed as a part of the combined treatment and prophylactic measures. Lysozyme was added to the donor breast milk or to the dry adapted acidophilic mixture \"Malyutka\" in an amount of 50 mg per 1 liter of the final product. 29 infants were feeded with such milk products for 14-21 days of the observation period. The control group included 12 infants with artificial feeding and 23 infants feeded with the above milk products without addition of lysozyme. In spite of the significant differences in the initial state of the infants, a favourable effect of the feeding with addition of lysozyme was shown. It was comparable to the feeding with the breast milk. Improvement of the general state of the infants and the pathological processes in them, an increase in the body weight, more rapid sanation of the infectious inflammatory foci, normalization of the stool, stabilization of the lysozyme levels in the coprofiltrates and a tendency to normalization of the increased levels of lysozyme in the blood serum were observed. Satisfactory tolerance of the lysozyme enriched milk products was shown.","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 10","pages":"784-90"},"PeriodicalIF":0.0,"publicationDate":"1984-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17566028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Optical properties of DNA complexes with antitumor compounds of bivalent platinum]. [抗肿瘤二价铂DNA复合物的光学性质]。

Antibiotiki Pub Date : 1984-10-01

N M Akimenko, Z Balcarová, V Kleinwächter, Iu M Evdokimov

{"title":"[Optical properties of DNA complexes with antitumor compounds of bivalent platinum].","authors":"N M Akimenko, Z Balcarová, V Kleinwächter, Iu M Evdokimov","doi":"","DOIUrl":"","url":null,"abstract":"The optical properties of the DNA complexes with the compounds of bivalent platinum were studied. The compounds differed by the nature of the anionic and neutral ligands and their spatial arrangement about the platinum atom. It was shown that the same as cis-[Pt (NH3)2Cl2] the platinum compounds with the biological activity, i.e. [Pt (en) Cl2], cis-[PtNH3 (Bz) Cl2] and cis-[Pt (NH3)2NO2Cl] induced at low values of r (a ratio of the number of the platinum moles added to the number of the DNA nucleotide moles in the solution) an increase in the amplitude of the positive band in the spectrum of the circular dichroism (CD) of the linear DNA and a marked decrease in the amplitude of the negative band in the spectrum of the CD of the liquid crystalline microphase of DNA formed in the presence of polyethyleneglycol. By the character of the action on the CD spectrum of the linear and condensed DNA [Pt (tetrameen)Cl2] which had no selective antimitotic effect might be referred to the above platinum compounds. Trans-[Pt (NH3)2NO2Cl], [PtNH3PyCl2], cis-[Pt (NH3)2(NO2)2] and [Pt (NH3)3Cl]Cl having no biological activity either induced only a decrease in the amplitude of the positive band in the CD spectrum of the linear DNA or had no effect on the CD spectrum. The effect of these compounds on the CD spectrum of the liquid crystalline microphase of DNA was slightly pronounced or not observed.","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 10","pages":"743-8"},"PeriodicalIF":0.0,"publicationDate":"1984-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17566991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Interdependence of mycelial dehydrogenase activity in Streptomyces aureofaciens and its capacity for tetracycline biosynthesis]. [金黄色链霉菌菌丝脱氢酶活性与其四环素生物合成能力的相互依赖性]。

Antibiotiki Pub Date : 1984-10-01

L M Novikova, V G Makarevich

引用次数: 0

[Optical density changes in bacterial protoplast suspensions exposed to membrane-active antibiotics]. [接触膜活性抗生素的细菌原生质体悬浮液的光密度变化]。

Antibiotiki Pub Date : 1984-10-01

V G Bulgakova, P N Korolev, Z M Petrykina, T Iu Novozhilova, A N Polin

{"title":"[Optical density changes in bacterial protoplast suspensions exposed to membrane-active antibiotics].","authors":"V G Bulgakova, P N Korolev, Z M Petrykina, T Iu Novozhilova, A N Polin","doi":"","DOIUrl":"","url":null,"abstract":"The effect of membrane active antibiotics, such as gramicidin S, its derivatives and carbonyl-conjugated pentaens on suspended bacterial protoplasts resulted in lysis of the protoplasts accompanied by a marked decrease in the optical density (OD) of the suspensions. However, when the drug concentrations were lower than those inducing the lysis, an increase in the suspension OD by 10-30 per cent as compared to the control values of the OD was often observed. The increase in the protoplast suspension OD was most pronounced with the use of the drugs with a relatively low lytic activity or under the conditions lowering the lytic activity of the antibiotics. Under such conditions no agglutination of the protoplasts was observed. The comparative estimation of the protoplast diameters by the method of Klenin et al. in the control suspensions of M. lysodeikticus protoplasts and in the suspensions with a stable increase in the OD showed that the OD increase was associated with swelling of the protoplasts: an increase in the suspension OD by approximately 30 per cent corresponded to an increase in the protoplast diameter by approximately 15 per cent. The observed increasing of the suspension OD must be due to the fact that the membrane active antibiotics induced a decrease in the osmotic stability of the protoplasts not sufficient for their lysis.","PeriodicalId":7959,"journal":{"name":"Antibiotiki","volume":"29 10","pages":"756-60"},"PeriodicalIF":0.0,"publicationDate":"1984-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17496982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A method of diffusion in agar for determining streptococcal sensitivity to antibiotics]. 用琼脂扩散法测定链球菌对抗生素的敏感性。

Antibiotiki Pub Date : 1984-10-01

N I Givental', S K Osmanov, L F Bogdanova, T N Ratnikova, O A Krasil'nikova

引用次数: 0

[Bacteriocins of species of the genus Pseudomonas]. [假单胞菌属的细菌素]。

Antibiotiki Pub Date : 1984-10-01

V V Smirnov, E A Kiprianova, A D Garagulian, V I Ruban, T A Dodatko

引用次数: 0