Administration in social work最新文献

Of mice and men: correlations between microRNA-17∼92 cluster expression and promoter methylation in severe bronchopulmonary dysplasia. 小鼠与人类：严重支气管肺发育不良的 microRNA-17∼92 簇表达与启动子甲基化之间的相关性。

IF 3.6

Administration in social work Pub Date : 2016-11-01 Epub Date: 2016-09-30 DOI: 10.1152/ajplung.00390.2016

Mary E Robbins, Duaa Dakhlallah, Clay B Marsh, Lynette K Rogers, Trent E Tipple

{"title":"Of mice and men: correlations between microRNA-17∼92 cluster expression and promoter methylation in severe bronchopulmonary dysplasia.","authors":"Mary E Robbins, Duaa Dakhlallah, Clay B Marsh, Lynette K Rogers, Trent E Tipple","doi":"10.1152/ajplung.00390.2016","DOIUrl":"10.1152/ajplung.00390.2016","url":null,"abstract":"<p><p>We previously demonstrated that decreased miR-17∼92 cluster expression was 1) present in lungs from human infants who died with bronchopulmonary dysplasia (BPD); 2) inversely correlated with DNA methyltransferase (DNMT) expression and promoter methylation; and 3) correlated with a subsequent diagnosis of BPD at 36 wk gestational age. We tested the hypothesis that plasma miR-17 levels would be lowest in infants who ultimately develop severe BPD. Secondly, we utilized our well-characterized murine model of severe BPD that combines perinatal inflammation with postnatal hyperoxia to test the hypothesis that alterations in lung miR-17∼92, DNMT, and promoter methylation in our model would mirror our findings in tissues from premature human infants. Plasma was obtained during the first 5 days of life from premature infants born ≤32 wk gestation. Lung tissues were harvested from mice exposed to maternal inflammation and neonatal hyperoxia for 14 days after birth. miR-17∼92 cluster expression and DNA methyltransferase expression were measured by qRT-PCR, and promoter methylation was assessed by Methyl-Profiler assay. Plasma miR-17 levels are significantly lower in the first week of life in human infants who develop severe BPD compared with mild or moderate BPD. Data from our severe BPD murine model reveal that lung miR-17∼92 cluster expression is significantly attenuated, and levels inversely correlated with DNMT expression and miR-17∼92 cluster promoter methylation. Collectively, our data support a plausible role for epigenetically altered miR-17∼92 cluster in the pathogenesis of severe BPD.</p>","PeriodicalId":79549,"journal":{"name":"Administration in social work","volume":"31 1","pages":"L981-L984"},"PeriodicalIF":3.6,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88939094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leading Change in Multiple Contexts: Concepts and Practices in Organizational, Community, Political, Social and Global Settings, by Gill Robinson Hickman 吉尔·罗宾逊·希克曼著，《在多种环境下领导变革:组织、社区、政治、社会和全球环境中的概念和实践》

Administration in social work Pub Date : 2013-11-01 DOI: 10.1080/03643107.2013.801297

Laura Nissen

引用次数: 4

The Control Function of Social Services in Spanish Local Government: A Contribution to Transparency and Performance Improvement 西班牙地方政府社会服务的控制功能:对透明度和绩效改进的贡献

Administration in social work Pub Date : 2013-11-01 DOI: 10.1080/03643107.2013.828001

Carolina Pontones Rosa, Rosario Pérez Morote

引用次数: 1

Editorial Board, EOV 编辑委员会，EOV

Administration in social work Pub Date : 2013-11-01 DOI: 10.1080/03643107.2013.847352

引用次数: 0

Strategic Leadership and Management in Nonprofit Organizations: Theory and Practice, Martha Golensky 《非营利组织的战略领导与管理:理论与实践》，玛莎·戈伦斯基著

Administration in social work Pub Date : 2013-10-17 DOI: 10.1080/03643107.2013.801305

Lauri Goldkind

引用次数: 2

Developing a Social Enterprise as a Social Worker 作为社会工作者发展社会企业

Administration in social work Pub Date : 2013-10-08 DOI: 10.1080/03643107.2013.828000

K. Linton

引用次数: 12

My Team Members Are Everywhere! A Critical Analysis of the Emerging Literature on Dispersed Teams 我的团队成员无处不在!对分散团队新兴文献的批判性分析

Administration in social work Pub Date : 2013-10-08 DOI: 10.1080/03643107.2013.828002

S. A. Allen, Halaevalu F. Ofahengaue Vakalahi

引用次数: 8

Making It Work: Administrator Views on Sustaining Evidence-Based Mental Health Interventions 使其发挥作用:管理者对维持循证心理健康干预的看法

Administration in social work Pub Date : 2013-09-12 DOI: 10.1080/03643107.2013.828003

K. K. Raffel, M. Lee, C. Dougherty, G. Greene

引用次数: 12

The 7C Approach to Conceptualizing Administration: Executive Leadership in the 21st Century 管理概念的7C方法:21世纪的行政领导

Administration in social work Pub Date : 2013-09-01 DOI: 10.1080/03643107.2013.831714

J. Tropman, L. Wooten

{"title":"The 7C Approach to Conceptualizing Administration: Executive Leadership in the 21st Century","authors":"J. Tropman, L. Wooten","doi":"10.1080/03643107.2013.831714","DOIUrl":"https://doi.org/10.1080/03643107.2013.831714","url":null,"abstract":"The field of administration of organizations is huge. There are about 1.1 million 501©3 organizations in 2011 (Independent Sector). Each has a CEO, and other top administrators. Let’s assume an average of 4—which would generate 5.5 million Executive Leaders. On the operation level there are huge questions about how these individuals are recruited, trained and educated, paid, replaced and so on. Then there are questions about what, actually, should they DO? And on the conceptual level, there are questions about how we understand the thousands of pieces of writing—both popular and scholarly—about Administration and Executive Leadership. This editorial makes two overall points. One is that the taxonomic device discussed here— the 7Cs—is a good way to think about Executive Leadership and that vast literature. Second the word “Administration” is made up of two parts—Executiveship—the tactical/management part, and Leadership—the strategic/visioning and strategic. Further, as is perhaps evident from the previous definition—Executiveship and Leadership conflict with each other. Many of us are oriented more one way or the other and a few are nimble enough to do both, each when necessary. Let’s discuss each in turn.","PeriodicalId":79549,"journal":{"name":"Administration in social work","volume":"37 1","pages":"325 - 328"},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/03643107.2013.831714","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59423682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Management for Social Enterprise. Bob Doherty, George Foster, Chris Mason, John Meehan, Karon Meehan, Neil Rotheroe, & Maureen Royce “社会企业管理”鲍勃·多尔蒂、乔治·福斯特、克里斯·梅森、约翰·米汉、卡伦·米汉、尼尔·罗瑟罗和莫林·罗伊斯

Administration in social work Pub Date : 2013-09-01 DOI: 10.1080/03643107.2013.801298

M. Nandan

引用次数: 0