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Ageing and the brain, a first glimpse at age-induced altered gene expression 衰老和大脑，第一次看到年龄引起的基因表达改变
Molecular medicine today Pub Date : 2000-10-01 DOI: 10.1016/S1357-4310(00)01794-9
Luc Smink PhD
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引用次数: 1
Murine models of malignant melanoma 恶性黑色素瘤小鼠模型
Molecular medicine today Pub Date : 2000-10-01 DOI: 10.1016/S1357-4310(00)01781-0
Maja K Tietze MD (Research Fellow), Lynda Chin MD (Assistant Professor of Dermatology)
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引用次数: 24
Protein aggregation in Huntington’s and Parkinson’s disease: implications for therapy 亨廷顿氏病和帕金森病的蛋白质聚集:对治疗的影响
Molecular medicine today Pub Date : 2000-10-01 DOI: 10.1016/S1357-4310(00)01761-5
Erich E Wanker PhD (Group Leader)
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引用次数: 49
X-linked severe combined immunodeficiency: from molecular cause to gene therapy within seven years x连锁严重联合免疫缺陷:7年内从分子病因到基因治疗
Molecular medicine today Pub Date : 2000-10-01 DOI: 10.1016/S1357-4310(00)01782-2
Warren J Leonard MD (Chief, Laboratory of Molecular Immunology)
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引用次数: 20
Coronary artery disease: new findings, better technology, new therapies? 冠状动脉疾病:新的发现，更好的技术，新的治疗方法?
Molecular medicine today Pub Date : 2000-10-01 DOI: 10.1016/S1357-4310(00)01780-9
Martin Braddock PhD
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引用次数: 0
Changing Trends 变化趋势
Molecular medicine today Pub Date : 2000-10-01 DOI: 10.1016/S1357-4310(00)01793-7
Karen Rooke (Editor)
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引用次数: 0
Communication genes clustered on 7q31 交流基因聚集在7q31上
Molecular medicine today Pub Date : 2000-10-01 DOI: 10.1016/S1357-4310(00)01790-1
Michele Ramsay
{"title":"Communication genes clustered on 7q31","authors":"Michele Ramsay","doi":"10.1016/S1357-4310(00)01790-1","DOIUrl":"10.1016/S1357-4310(00)01790-1","url":null,"abstract":"","PeriodicalId":79448,"journal":{"name":"Molecular medicine today","volume":"6 10","pages":"Pages 380-381"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1357-4310(00)01790-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21839841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Peptic ulcer irony 消化性溃疡讽刺
Molecular medicine today Pub Date : 2000-10-01 DOI: 10.1016/S1357-4310(00)01784-6
Jodi A. Lindsay
{"title":"Peptic ulcer irony","authors":"Jodi A. Lindsay","doi":"10.1016/S1357-4310(00)01784-6","DOIUrl":"10.1016/S1357-4310(00)01784-6","url":null,"abstract":"","PeriodicalId":79448,"journal":{"name":"Molecular medicine today","volume":"6 10","pages":"Page 382"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1357-4310(00)01784-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21839843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Secretases as targets for the treatment of Alzheimer’s disease 分泌酶作为治疗阿尔茨海默病的靶点
Molecular medicine today Pub Date : 2000-10-01 DOI: 10.1016/S1357-4310(00)01759-7
Martin Citron (Senior Scientist)
{"title":"Secretases as targets for the treatment of Alzheimer’s disease","authors":"Martin Citron (Senior Scientist)","doi":"10.1016/S1357-4310(00)01759-7","DOIUrl":"10.1016/S1357-4310(00)01759-7","url":null,"abstract":"<div><p>Alzheimer’s disease (AD) is the major cause of dementia in most developed countries. Treatment to modify this disease is currently unavailable, but needed urgently. The amyloid-cascade hypothesis proposes that amyloid β-peptide (Aβ), found in the plaques characteristic of AD, plays an early, critical role in the disease process. It follows that preventing the generation of Aβ could be therapeutically useful in all cases of AD. Inhibition of the secretases that produce Aβ from a large precursor protein is the main approach to achieve this goal.</p></div>","PeriodicalId":79448,"journal":{"name":"Molecular medicine today","volume":"6 10","pages":"Pages 392-397"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1357-4310(00)01759-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21839846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 48
Kaposi’s sarcoma-associated virus mounts novel attack on immune system 卡波西氏肉瘤相关病毒对免疫系统发起了新的攻击
Molecular medicine today Pub Date : 2000-10-01 DOI: 10.1016/S1357-4310(00)01786-X
Martina Habeck (Freelance science writer)
{"title":"Kaposi’s sarcoma-associated virus mounts novel attack on immune system","authors":"Martina Habeck (Freelance science writer)","doi":"10.1016/S1357-4310(00)01786-X","DOIUrl":"10.1016/S1357-4310(00)01786-X","url":null,"abstract":"","PeriodicalId":79448,"journal":{"name":"Molecular medicine today","volume":"6 10","pages":"Page 377"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1357-4310(00)01786-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21839837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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