发布求助
文献互助 智能选刊 最新文献

Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine最新文献

筛选
英文 中文
[Autologous blood donation with preliminary erythropoietin stimulation]. 自体献血加促红细胞生成素刺激。
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine Pub Date : 1996-01-01
S Sipurzynski-Budrass, U Posch, E Stubenvoll, H Gombotz, G Lanzer
{"title":"[Autologous blood donation with preliminary erythropoietin stimulation].","authors":"S Sipurzynski-Budrass,&nbsp;U Posch,&nbsp;E Stubenvoll,&nbsp;H Gombotz,&nbsp;G Lanzer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Low basal hemoglobin and functional iron deficiency are the limiting factors in autologous blood donation program. Treatment with recombinant human erythropoietin can increase the volume of autologous blood and makes donation of > or = 3 units possible-even in patients with low basal hemoglobin. Best results are obtained if stimulation begins already one week before first donation.</p>","PeriodicalId":79439,"journal":{"name":"Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine","volume":"33 ","pages":"201-5"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19936475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Nanofiltration in production of Beriplex P/N: increasing the capacity of virus elimination while maintaining product quality]. [Beriplex P/N生产中的纳滤:在保持产品质量的同时提高病毒消除能力]。
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine Pub Date : 1996-01-01
J Römisch, A Gröner, D Bernhardt, K H Diehl, B Hein, W List, H G Müller, T Nowak, H Ronneberger, E Schüler, T Weimer, J Hilfenhaus
{"title":"[Nanofiltration in production of Beriplex P/N: increasing the capacity of virus elimination while maintaining product quality].","authors":"J Römisch,&nbsp;A Gröner,&nbsp;D Bernhardt,&nbsp;K H Diehl,&nbsp;B Hein,&nbsp;W List,&nbsp;H G Müller,&nbsp;T Nowak,&nbsp;H Ronneberger,&nbsp;E Schüler,&nbsp;T Weimer,&nbsp;J Hilfenhaus","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>For the manufacture of the PCC Beriplex P/N, nanofiltration was introduced into the production process of Beriplex HS providing an additional means to heat treatment for the clearance/inactivation of viruses. By nanofiltration, large enveloped viruses (HSV-1, HIV-1) were completely eliminated by a factor of more than 7 log10. While medium-sized enveloped viruses (HBV, BVDV) were cleared by a factor of approximately 4 log10, small non-enveloped viruses (poliovirus) were not removed. The product profile remained, no thrombogenic activities were detected.</p>","PeriodicalId":79439,"journal":{"name":"Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine","volume":"33 ","pages":"220-4"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19936479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Prevalence of hepatitis C virus in blood donors and comparison of 4 different anti-HCV differentiation tests]. 献血者丙型肝炎病毒患病率及4种不同抗丙型肝炎病毒分化检测的比较
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine Pub Date : 1996-01-01
H Hennig, D Haase, H Kirchner
{"title":"[Prevalence of hepatitis C virus in blood donors and comparison of 4 different anti-HCV differentiation tests].","authors":"H Hennig,&nbsp;D Haase,&nbsp;H Kirchner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 1994 we tested 30,208 blood donations in Lübeck with the Abbott HCV EIA 2.0. 88 specimens of 47 blood donors who were repeatedly reactive were the basis of comparative investigations with the Chiron RIBA HCV 2.0 and 3.0, the Abbott Matrix HCV, the Wellcozyme HCV Western Blot (Murex) and the PCR (Amplicor HCV Test, Roche Diagnostic Systems). Our results suggest that the minimal prevalence of HCV RNA amounts to approximately 0.13%, the incidence per year to 0.013%. The minimal prevalence of anti-HCV amounts to 0.27%. Anti-core antibodies are the most frequent anti-HCV antibodies. They may be the only detectable antibodies during the early phase of the infection. The Chiron RIBA HCV 3.0 with the synthetic peptide c22p is not sufficiently sensitive for anti-core antibodies and may therefore fail to recognize viremic specimens.</p>","PeriodicalId":79439,"journal":{"name":"Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine","volume":"33 ","pages":"231-4"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19936991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Rheologic changes in stored erythrocyte concentrates]. [储存红细胞浓缩物的流变学变化]。
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine Pub Date : 1996-01-01
E P Zilow, G Zilow, P Ruef, O Linderkamp
{"title":"[Rheologic changes in stored erythrocyte concentrates].","authors":"E P Zilow,&nbsp;G Zilow,&nbsp;P Ruef,&nbsp;O Linderkamp","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We studied the effect of two different preservation solutions on mean corpuscular volume (MCV), red cell deformability and flow in narrow tubes in red blood cell concentrates. Blood from 10 healthy blood donors was processed in parallel in SAG-M (S-RBC) as well as in PAGGS-M (P-RBC) in identical aliquots. Samples were studied at days 0, 7, 14, 28 and 42 of storage. MCV was determined using a Du Pont cell counter. Whole cell deformability was determined in a Myrenne Rheodyn. Viscosity reduction in narrow tubes was determined by means of capillary viscosimetry. P-RBC showed a constant MCV over the entire storage period. In contrast, MCV of S-RBC increased and MCHC decreased during storage. P-RBC showed similar deformability and viscosity reduction during storage, whereas deformability decreased and viscosity reduction became less pronounced for S-RBC. Our study shows superior rheological properties of P-RBC. Thus, PAGGS-M may provide better hemoglobin flux and oxygen transport to tissues than SAG-M.</p>","PeriodicalId":79439,"journal":{"name":"Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine","volume":"33 ","pages":"136-40"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19938532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improved automated bone marrow processing and enrichment of CD34+ cells by a large-volume apheresis procedure. 通过大容量分离程序改进骨髓自动处理和富集CD34+细胞。
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine Pub Date : 1996-01-01
U Cassens, H Garritsen, R Ernst, H Jürgens, W Sibrowski
{"title":"Improved automated bone marrow processing and enrichment of CD34+ cells by a large-volume apheresis procedure.","authors":"U Cassens,&nbsp;H Garritsen,&nbsp;R Ernst,&nbsp;H Jürgens,&nbsp;W Sibrowski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We investigated the efficacy of bone marrow (bm) processing by a large-volume apheresis procedure using a self constructed sixfold collection bag system for sequential cell collection and analysis for 5 pediatric patients. Quantitation of leukocytes (WBC), CD34+ cells and colony-forming cells (CFU-GM) within the single bags showed a relative time-dependent decrease of all cell fractions during leukapheresis, whereas the relative amount of mononuclear cells (MNC) droped only slightly. At the same time the large volume apheresis (6 x original bm-volume) clearly enhanced the absolute yield of CD34+ cells compared to the standard procedure (3 x bm-volume) for more than 20%. We conclude that large-volume apheresis for bm processing is an efficient technique to improve the yields of progenitor cells.</p>","PeriodicalId":79439,"journal":{"name":"Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine","volume":"33 ","pages":"175-9"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19831541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous vs. oral iron supplementation during autologous blood donation. 自体献血期间静脉补铁与口服补铁比较。
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine Pub Date : 1996-01-01
M Gesemann, I Mielsch, P R Gentner, H Weigand, N Scheiermann
{"title":"Intravenous vs. oral iron supplementation during autologous blood donation.","authors":"M Gesemann,&nbsp;I Mielsch,&nbsp;P R Gentner,&nbsp;H Weigand,&nbsp;N Scheiermann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Prior to hip replacement surgery, 197 patients (123 women, 74 men, age 18-86 years) donated up to 4 units of blood once weekly if their hemoglobin concentrations exceeded 11.5 g/dl. They received an oral (200 mg iron sulfate daily) or intravenous (200 mg iron saccharate or 125 mg iron gluconate in 500 ml 0.9% NaCl weekly) iron replacement. Correlating the number of donated blood units with the form of iron substitution, no effect of i.v. iron was seen in men. Women who received i.v. iron substitution were able to donate 4 units of blood more often than with oral iron.</p>","PeriodicalId":79439,"journal":{"name":"Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine","volume":"33 ","pages":"180-3"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19831542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transfusion medicine 1995/96. Proceedings of the 28th Congress of the German Society of Transfusion Medicine and Immunohematology. Wien, 17-20 September 1995. 输血医学1995/96。德国输血医学和免疫血液学学会第28届大会论文集。维也纳，1995年9月17日至20日。
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine Pub Date : 1996-01-01
{"title":"Transfusion medicine 1995/96. Proceedings of the 28th Congress of the German Society of Transfusion Medicine and Immunohematology. Wien, 17-20 September 1995.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79439,"journal":{"name":"Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine","volume":"33 ","pages":"1-268"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19935966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cryopreservation of erythrocytes: detailed quality control]. 红细胞冷冻保存:详细的质量控制。
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine Pub Date : 1996-01-01
S Lippert, M Böck, S Rahrig, H Kreutzmann, M U Heim
{"title":"[Cryopreservation of erythrocytes: detailed quality control].","authors":"S Lippert,&nbsp;M Böck,&nbsp;S Rahrig,&nbsp;H Kreutzmann,&nbsp;M U Heim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It has been well established that cryopreservation of red cells with glycerol is a suitable method for long-time storage. Therefore, many data for quality control have been published. Most measurements, however, are restricted to the final product. Less information is available about the particular steps of cryopreservation. The present paper describes in detail the results of quality control measurements during the procedure. Although the final product meets the demand of the WHO for cryopreserved red cells, it could be demonstrated that erythrocytes are remarkably damaged by the deep-freezing process. Further experiments seem to be necessary in order to improve the details of the deep-freezing procedure.</p>","PeriodicalId":79439,"journal":{"name":"Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine","volume":"33 ","pages":"117-20"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19935968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Solid phase technique versus gel centrifugation for detection of erythrocyte antibodies--a prospective study comparison the 2 antibody detection tests]. 【固相技术与凝胶离心检测红细胞抗体——两种抗体检测方法的前瞻性研究比较】。
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine Pub Date : 1996-01-01
T Zeiler, S Thiele, V Kretschmer
{"title":"[Solid phase technique versus gel centrifugation for detection of erythrocyte antibodies--a prospective study comparison the 2 antibody detection tests].","authors":"T Zeiler,&nbsp;S Thiele,&nbsp;V Kretschmer","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aim: </strong>To define differences of specifity and sensitivity between a solid phase- and a gel centrifugation test for detection of irregular erythrocyte antibodies.</p><p><strong>Study design: </strong>3052 blood samples were screened for erythrocyte antibodies (AB) by gel centrifugation [ID-System, (ID) 37 degrees C Bromelin and indirect antiglobulin test with LISS (IAT)] and a solid phase antiglobulin test [Capture-R Ready Screen (CR)] in a prospective study. Identical test cells were used as immobilized monolayer in CR and as 1%-suspension in ID. Additionally, 42 sera with antibodies reacting in both tests were titered geometrically in both techniques.</p><p><strong>Results: </strong>In 79 (2.6%) of all sera tested, irregular erythrocyte antibodies were detected. 64 (81%) of these positive sera were detected by both tests, 73 (92.3%) by ID and 70 (88.4%) by CR. 6 sera with AB (7.6%) were positive only with CR (1 Ce, 1 E, 1 Leb, 1 C, 1 D, 1 Cob) and 9 (11.4%) only with ID (4 Lea, 1 Fya, 1 C, 2 P1, 1 D). Seven AB solely detected in ID only reacted in the bromelin test, besides an anti-Fya, which was an IgM antibody. The titration of IgG antibodies showed a slightly higher sensitivity of the CR (less than one titre step). The ID showed clearly more unspecific reactions (1.1%) than the CR (0.5%).</p><p><strong>Discussion: </strong>The antibody screening with the ID proved to detect more AB than the CR (mainly due to certainly irrelevant \"enzyme only\" AB). On the other hand, relevant IgG AB were detected more sensitive by the CR. Unspecific reactions appeared clearly more often in ID, predominantly when using the bromelin test. Missing a strong IgM anti-Fya in the CR is certainly a concern because of its assumed haemolytic activity. Therefore CR for antibody screening should always be combined with a method for crossmatching that safely detects IgM antibodies which are relevant for transfusion.</p>","PeriodicalId":79439,"journal":{"name":"Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine","volume":"33 ","pages":"17-21"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19936472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In-line filtration of SAG-M red cell concentrates prepared in top/bottom or conventional bag systems. 在顶部/底部或传统袋式系统中制备的SAG-M红细胞浓缩液的在线过滤。
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine Pub Date : 1996-01-01
N Müller
{"title":"In-line filtration of SAG-M red cell concentrates prepared in top/bottom or conventional bag systems.","authors":"N Müller","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>SAG-M RCCs were prepared in triple conventional or quadruple top/bottom bag systems and filtered at +4 degrees C using the in-line filter system Leucoflex LCR 4 Macopharma after 16-24-30 h of storage. Postfiltration WBC content was determined by Nageotte hemocytometer counting. The mean WBC content of the units prepared in conventional bag systems and filtered was higher than that of the units prepared in T/B bag systems. The best results could be obtained in T/B RCCs stored for 24 h; potassium and hemolysis levels were also improved. The Leucoflex LCR 4 in-line filter T/B system can be recommended for application in the clinical routine by virtue of the effective leukocyte elimination.</p>","PeriodicalId":79439,"journal":{"name":"Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine","volume":"33 ","pages":"121-4"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19831537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信