Annals of General Psychiatry最新文献

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Effect of the decreased frequency of going out on the association between anxiety and sleep disorder during the COVID-19 pandemic: a mediation analysis. 新冠肺炎大流行期间外出频率降低对焦虑和睡眠障碍之间关系的影响:一项中介分析。
IF 3.7 3区 医学
Annals of General Psychiatry Pub Date : 2023-07-23 DOI: 10.1186/s12991-023-00456-z
Yumi Sugawara, Yutaka Yabe, Yoshihiro Hagiwara, Ichiro Tsuji
{"title":"Effect of the decreased frequency of going out on the association between anxiety and sleep disorder during the COVID-19 pandemic: a mediation analysis.","authors":"Yumi Sugawara,&nbsp;Yutaka Yabe,&nbsp;Yoshihiro Hagiwara,&nbsp;Ichiro Tsuji","doi":"10.1186/s12991-023-00456-z","DOIUrl":"10.1186/s12991-023-00456-z","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of the present study was to examine the relationship between anxiety and sleep disorder during the COVID-19 pandemic and to evaluate whether sleep disorder is mediated by the decreased frequency of going out.</p><p><strong>Methods: </strong>The data of a total of 1976 residents aged 18 years and over who had responded to a self-reported questionnaires at a health survey in 2020 were analyzed. The subjects were divided into four groups based on their response to the questionnaire on anxiety about the COVID-19 pandemic. Sleep disorder was measured using the Athens Insomnia Scale (AIS). A cross-sectional analysis was performed to examine the association between anxiety about the COVID-19 pandemic and AIS scores. Mediation analysis was used to calculate the association between anxiety and AIS scores during the COVID-19 pandemic, with decreased frequency of going out as a potential mediating variable.</p><p><strong>Results: </strong>In the cross-sectional study, the level of anxiety about the COVID-19 pandemic was significantly associated with the AIS score (p < 0.001). On mediation analysis, the direct effect of the relationship showed that anxiety positively influenced AIS scores (β = 0.283, p < 0.01). The indirect effect of the relationship showed that the decreased frequency of going out positively mediated the relationship between anxiety and AIS scores (β = 0.342, p < 0.05). The decreased frequency of going out accounted for almost 10% of the AIS score.</p><p><strong>Conclusion: </strong>The present study found that anxiety about the COVID-19 pandemic was significantly associated with sleep disorder, with the decreased frequency of going out mediating this association.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9924159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender differences in prevalence and associated factors of metabolic syndrome in first-treatment and drug-naïve schizophrenia patients. 首次治疗和drug-naïve精神分裂症患者代谢综合征患病率及相关因素的性别差异
IF 3.7 3区 医学
Annals of General Psychiatry Pub Date : 2023-06-28 DOI: 10.1186/s12991-023-00455-0
Kuan Zeng, Shuo Wang, Lin Zhang, Yanting Zhang, Jun Ma
{"title":"Gender differences in prevalence and associated factors of metabolic syndrome in first-treatment and drug-naïve schizophrenia patients.","authors":"Kuan Zeng,&nbsp;Shuo Wang,&nbsp;Lin Zhang,&nbsp;Yanting Zhang,&nbsp;Jun Ma","doi":"10.1186/s12991-023-00455-0","DOIUrl":"https://doi.org/10.1186/s12991-023-00455-0","url":null,"abstract":"<p><strong>Background: </strong>Metabolic syndromes (MetS) are clinical syndromes involving multiple pathological states with distinct gender-specific clinical patterns. As a serious disorder associated with psychiatric conditions, the prevalence of MetS is significantly higher in the population with schizophrenia (Sch). The aim of this paper is to report gender differences in the prevalence, associated factors and severity-related factors of MetS in first-treatment and drug-naïve (FTDN) patients with Sch.</p><p><strong>Methods: </strong>A total of 668 patients with FTDN Sch were included in this study. We collected socio-demographic and general clinical information on the target population, measured and evaluated common metabolic parameters and routine biochemical indicators, and assessed the severity of psychiatric symptoms using Positive and Negative Symptom Scale (PANSS).</p><p><strong>Results: </strong>In the target group, the prevalence of MetS was significantly higher in women (13.44%, 57/424) than in men (6.56%, 16/244). In the males, waist circumference (WC), fasting blood glucose (FBG), diastolic blood pressure (DBP), and triglycerides (TG) were risk factors for MetS, while systolic blood pressure (SBP), TG, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and platelet (PLT) were risk factors for the females. More importantly, for the females, we found that age, LDL-C, PANSS scores and blood creatinine (CRE) were risk factors for higher MetS scores, while onset age and hemoglobin (HGB) were protective factors.</p><p><strong>Conclusion: </strong>There are significant gender differences in the prevalence of MetS and its factors among patients with FTDN Sch. The prevalence of MetS is higher and the factors that influence MetS are more numerous and extensive in females. The mechanisms of this difference need further research and clinical intervention strategies should be formulated with gender differences.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10088415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Understanding inequalities in mental health by family structure during COVID-19 lockdowns: evidence from the UK Household Longitudinal Study. 了解 COVID-19 封锁期间因家庭结构造成的心理健康不平等:来自英国家庭纵向研究的证据。
IF 3.7 3区 医学
Annals of General Psychiatry Pub Date : 2023-06-06 DOI: 10.1186/s12991-023-00454-1
Michael J Green, Peter Craig, Evangelia Demou, S Vittal Katikireddi, Alastair H Leyland, Anna Pearce
{"title":"Understanding inequalities in mental health by family structure during COVID-19 lockdowns: evidence from the UK Household Longitudinal Study.","authors":"Michael J Green, Peter Craig, Evangelia Demou, S Vittal Katikireddi, Alastair H Leyland, Anna Pearce","doi":"10.1186/s12991-023-00454-1","DOIUrl":"10.1186/s12991-023-00454-1","url":null,"abstract":"<p><strong>Purpose: </strong>The COVID-19 pandemic increased psychiatric distress and impacts differed by family structure. We aimed to identify mechanisms contributing to these inequalities.</p><p><strong>Methods: </strong>Survey data were from the UK Household Longitudinal Study. Psychiatric distress (GHQ-12) was measured in April 2020 (first UK lockdown; n = 10,516), and January 2021 (lockdown re-introduced following eased restrictions; n = 6,893). Pre-lockdown family structure comprised partner status and presence of children (< 16 years). Mediating mechanisms included: active employment, financial strain, childcare/home-schooling, caring, and loneliness. Monte Carlo g-computation simulations were used to adjust for confounding and estimate total effects and decompositions into: controlled direct effects (effects if the mediator was absent), and portions eliminated (PE; representing differential exposure and vulnerability to the mediator).</p><p><strong>Results: </strong>In January 2021, after adjustment, we estimated increased risk of distress among couples with children compared to couples with no children (RR: 1.48; 95% CI 1.15-1.82), largely because of childcare/home-schooling (PE RR: 1.32; 95% CI 1.00-1.64). Single respondents without children also had increased risk of distress compared to couples with no children (RR: 1.55; 95% CI 1.27-1.83), and the largest PE was for loneliness (RR: 1.16; 95% CI 1.05-1.27), though financial strain contributed (RR: 1.05; 95% CI 0.99-1.12). Single parents demonstrated the highest levels of distress, but confounder adjustment suggested uncertain effects with wide confidence intervals. Findings were similar in April 2020 and when stratified by sex.</p><p><strong>Conclusion: </strong>Access to childcare/schooling, financial security and social connection are important mechanisms that need addressing to avoid widening mental health inequalities during public health crises.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9651867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep disorders related to index and comorbid mental disorders and psychotropic drugs. 与睡眠障碍相关的指数和共病精神障碍及精神药物。
IF 3.7 3区 医学
Annals of General Psychiatry Pub Date : 2023-05-27 DOI: 10.1186/s12991-023-00452-3
Ray M Merrill, McKay K Ashton, Emily Angell
{"title":"Sleep disorders related to index and comorbid mental disorders and psychotropic drugs.","authors":"Ray M Merrill,&nbsp;McKay K Ashton,&nbsp;Emily Angell","doi":"10.1186/s12991-023-00452-3","DOIUrl":"https://doi.org/10.1186/s12991-023-00452-3","url":null,"abstract":"<p><strong>Purpose: </strong>Mental disorders positively associate with sleep disorders. This study will explore the moderating influence of comorbid mental disorders and whether selected psychotropic drugs correlate with sleep disorders after adjusting for mental disorders.</p><p><strong>Methods: </strong>A retrospective cohort study design was employed using medical claim data from the Deseret Mutual Benefit Administrators (DMBA). Mental disorders, psychotropic drug use, and demographic data were extracted from claim files for ages 18-64, years 2016-2020.</p><p><strong>Results: </strong>Approximately 11.7% filed one or more claims for a sleep disorder [insomnia (2.2%) and sleep apnea (9.7%)]. Rates for selected mental disorders ranged from 0.09% for schizophrenia to 8.4% for anxiety. The rate of insomnia is greater in those with bipolar disorder or schizophrenia than in other mental disorders. The rate of sleep apnea is greater in those with bipolar disorder and depression. There is a significantly positive association between mental disorders and insomnia and sleep apnea, more so for insomnia, especially if they had other comorbid mental disorders. Psychotropic drugs other than CNS stimulants, primarily sedatives (non-barbiturate) and psychostimulants, explain much of the positive association between anxiety, depression, and bipolar disorder with insomnia. Psychotropic drugs with the largest effect on sleep disorders are sedatives (non-barbiturate) and psychostimulants for insomnia and psychostimulants and anticonvulsants for sleep apnea.</p><p><strong>Conclusion: </strong>Mental disorders positively correlate with insomnia and sleep apnea. The positive association is greater when multiple mental illness exists. Bipolar disorder and schizophrenia are most strongly associated with insomnia, and bipolar disorder and depression are most strongly associated with sleep disorders. Psychotropic drugs other than CNS stimulants, primarily sedatives (non-barbiturate) and psychostimulants for treating anxiety, depression, or bipolar disorder are associated with higher levels of insomnia and sleep apnea.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2023-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9544827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The relationship between coping strategies with sexual satisfaction and sexual intimacy in women with multiple sclerosis. 多发性硬化症女性患者的应对策略与性满意度和性亲密关系之间的关系。
IF 3.6 3区 医学
Annals of General Psychiatry Pub Date : 2023-05-25 DOI: 10.1186/s12991-023-00451-4
Samaneh Imanpour Barough, Hedyeh Riazi, Zohreh Keshavarz, Maliheh Nasiri, Ali Montazeri
{"title":"The relationship between coping strategies with sexual satisfaction and sexual intimacy in women with multiple sclerosis.","authors":"Samaneh Imanpour Barough, Hedyeh Riazi, Zohreh Keshavarz, Maliheh Nasiri, Ali Montazeri","doi":"10.1186/s12991-023-00451-4","DOIUrl":"10.1186/s12991-023-00451-4","url":null,"abstract":"<p><strong>Background: </strong>Multiple sclerosis profoundly affects the sexual aspects of patients' life, especially in women. Various coping strategies are used by women with multiple sclerosis to overcome, tolerate, or minimize these sexual effects. The present study aimed to assess the relationship between sexual satisfaction, sexual intimacy, and coping strategies in women with multiple sclerosis.</p><p><strong>Methods: </strong>This cross-sectional study was performed on a sample of 122 married women who were members of Iran's MS society in Tehran, Iran. The study was conducted from December 2018 to September 2019. Data were collected using the Index of Sexual Satisfaction (ISS), the Sexual Intimacy Questionnaire (SIQ), and the Folkman and Lazarus Coping Strategies Questionnaire. Frequency, percentage, mean and standard deviation were used to explore the observations. Independent t-test and logistic regression were applied to analyze the data using the SPSS-23.</p><p><strong>Results: </strong>The majority (n = 71, 58.2%) used an emotion-focused coping strategy with the highest score for the escape-avoidance subscale [mean (SD): 13.29 (5.40)]. However, 41.8% of the patients (n = 51) used a problem-focused coping strategy with the highest score for the positive reappraisal strategy subscale [mean (SD): 10.50 (4.96)]. The sexual satisfaction in women with problem-focused coping strategies was significantly higher than women who used emotion-focused coping strategies (95.6 vs. 84.71, P-value = 0.001). There was a negative association between sexual intimacy and higher emotion-focused coping strategy (OR = 0.919, 95% CI 0.872-0.968, P = 0.001).</p><p><strong>Conclusions: </strong>Problem-focused coping strategy in women with multiple sclerosis increases sexual satisfaction, while the emotion-focused coping strategy has a significant negative relationship with sexual intimacy.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10210498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9524972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gut microbiota and its relation to inflammation in patients with bipolar depression: a cross-sectional study. 双相抑郁症患者肠道菌群及其与炎症的关系:一项横断面研究。
IF 3.7 3区 医学
Annals of General Psychiatry Pub Date : 2023-05-19 DOI: 10.1186/s12991-023-00453-2
Tingting Huang, Yushan Shang, Chunxiao Dai, Qixiu Zhang, Shaohua Hu, Jian Xie
{"title":"Gut microbiota and its relation to inflammation in patients with bipolar depression: a cross-sectional study.","authors":"Tingting Huang,&nbsp;Yushan Shang,&nbsp;Chunxiao Dai,&nbsp;Qixiu Zhang,&nbsp;Shaohua Hu,&nbsp;Jian Xie","doi":"10.1186/s12991-023-00453-2","DOIUrl":"https://doi.org/10.1186/s12991-023-00453-2","url":null,"abstract":"<p><strong>Background: </strong>To explore the gut microbiota characteristics in depressed patients with bipolar disorder (BD) as well as the connection between the gut microbiota and inflammatory markers.</p><p><strong>Methods: </strong>Totally 72 depressed BD patients and 16 healthy controls (HCs) were enrolled in the study. Blood and feces samples were taken from each subject. With the help of 16S-ribosomal RNA gene sequencing, the characteristics of the gut microbiota in each participant were examined. Correlation analysis was then utilized to assess the relationship between the gut microbiota and clinical parameters.</p><p><strong>Results: </strong>We found the taxonomic composition of the gut microbiota, but not its diversity, was significantly different in BD patients compared to HCs. We found the abundance of Bacilli, Lactobacillales and genus Veillonella were higher in BD patients than in HCs, while genus Dorea was more abundant in HCs. Additionally, correlation analysis showed that the bacterial genera' abundance in BD patients was strongly correlated with the severity of depression and inflammatory markers.</p><p><strong>Conclusions: </strong>According to these results, the gut microbiota characteristics were changed in depressed BD patients, which may have been associated with the severity of depression and the inflammatory pathways.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2023-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9853304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Study on association of serum uric acid levels with bipolar disorder: systematic review and meta-analysis in Chinese patients. 血清尿酸水平与双相情感障碍的相关性研究:中国患者的系统回顾和荟萃分析。
IF 3.7 3区 医学
Annals of General Psychiatry Pub Date : 2023-05-18 DOI: 10.1186/s12991-023-00450-5
Haihan Chen, Fengli Sun, Weidong Jin
{"title":"Study on association of serum uric acid levels with bipolar disorder: systematic review and meta-analysis in Chinese patients.","authors":"Haihan Chen,&nbsp;Fengli Sun,&nbsp;Weidong Jin","doi":"10.1186/s12991-023-00450-5","DOIUrl":"https://doi.org/10.1186/s12991-023-00450-5","url":null,"abstract":"<p><strong>Background: </strong>The purine system represented by uric acid may be involved in the pathogenesis of bipolar disorder, This study intends to explore the association of serum uric acid levels with bipolar disorder in Chinese patients through meta-analysis.</p><p><strong>Methods: </strong>Electronic databases, including PubMed, Embase, Web of Science, and China National Knowledge Infrastructure (CNKI), searching from inception to December 2022. Randomized Controlled Trials that reported serum uric acid levels and bipolar disorder were included. Two investigators independently extracted data and RevMan5.4 and Stata14.2 were used for statistical analyses.</p><p><strong>Results: </strong>Twenty-eight studies with 4482 bipolar disorder, 1568 depression, 785 schizophrenia, and 2876 healthy control subjects were included in this meta-analysis. The results of the meta-analysis showed that serum uric acid levels in the bipolar disorder group were significantly higher than those in depression [SMD 0.53 (0.37, 0.70), p < 0.00001], schizophrenia [SMD 0.27 (0.05, 0.49), p = 0.02] and healthy control group [SMD 0.87 (0.67, 1.06), p < 0.00001]. Subgroup-analysis showed that in Chinese people with bipolar disorder, uric acid levels of the manic episode were higher than the depressed episode [SMD 0.31 (0.22, 0.41), p < 0.00001].</p><p><strong>Conclusion: </strong>Our results indicated a strong association between serum uric acid levels and bipolar disorder in Chinese patients, but further studies about whether uric acid levels can be a biomarker for bipolar disorder still need to investigate.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9496362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alternation in functional connectivity within default mode network after psychodynamic psychotherapy in borderline personality disorder. 边缘型人格障碍心理动力治疗后默认模式网络功能连通性的变化。
IF 3.7 3区 医学
Annals of General Psychiatry Pub Date : 2023-05-11 DOI: 10.1186/s12991-023-00449-y
Saba Amiri, Fatemeh Sadat Mirfazeli, Jordan Grafman, Homa Mohammadsadeghi, Mehrdad Eftekhar, Nazila Karimzad, Maryam Mohebbi, Shabnam Nohesara
{"title":"Alternation in functional connectivity within default mode network after psychodynamic psychotherapy in borderline personality disorder.","authors":"Saba Amiri,&nbsp;Fatemeh Sadat Mirfazeli,&nbsp;Jordan Grafman,&nbsp;Homa Mohammadsadeghi,&nbsp;Mehrdad Eftekhar,&nbsp;Nazila Karimzad,&nbsp;Maryam Mohebbi,&nbsp;Shabnam Nohesara","doi":"10.1186/s12991-023-00449-y","DOIUrl":"https://doi.org/10.1186/s12991-023-00449-y","url":null,"abstract":"<p><strong>Background: </strong>Borderline personality disorder (BPD) is characterized by impairments in emotion regulation, impulse control, and interpersonal and social functioning along with a deficit in emotional awareness and empathy. In this study, we investigated whether functional connectivity (FC) within the default mode network (DMN) is affected by 1-year psychodynamic psychotherapy in patients with BPD.</p><p><strong>Methods: </strong>Nine BPD patients filled out the demography, Interpersonal Reactive Index (IRI), Toronto Alexithymia Scale 20 (TAS 20), the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST), and the Borderline Evaluation Severity over Time (BEST) questionnaire. The BPD group (9F) and the control group (9F) had a mean ± SD age of 28.2 ± 5.3 years and 30.4 ± 6.1 years, respectively. BPD subjects underwent longitudinal resting-state fMRI before psychodynamic psychotherapy and then every 4 months for a year after initiating psychotherapy. FC in DMN was characterized by calculating the nodal degree, a measure of centrality in the graph theory.</p><p><strong>Results: </strong>The results indicated that patients with BPD present with aberrant DMN connectivity compared to healthy controls. Over a year of psychotherapy, the patients with BPD showed both FC changes (decreasing nodal degree in the dorsal anterior cingulate cortex and increasing in other cingulate cortex regions) and behavioral improvement in their symptoms and substance use. There was also a significant positive association between the decreased nodal degree in regions of the dorsal cingulate cortex and a decrease in the score of the TAS-20 indicating difficulty in identifying feelings after psychotherapy.</p><p><strong>Conclusion: </strong>In BPD, there is altered FC within the DMN and disruption in self-processing and emotion regulation. Psychotherapy may modify the DMN connectivity and that modification is associated with positive changes in BPD emotional symptoms.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2023-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9457611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term consequences of COVID-19 on mental health and the impact of a physically active lifestyle: a narrative review. 2019冠状病毒病对心理健康的长期影响和积极运动生活方式的影响:述评
IF 3.7 3区 医学
Annals of General Psychiatry Pub Date : 2023-05-11 DOI: 10.1186/s12991-023-00448-z
Leonardo Roever, Bruno Raphael Ribeiro Cavalcante, Alex Cleber Improta-Caria
{"title":"Long-term consequences of COVID-19 on mental health and the impact of a physically active lifestyle: a narrative review.","authors":"Leonardo Roever,&nbsp;Bruno Raphael Ribeiro Cavalcante,&nbsp;Alex Cleber Improta-Caria","doi":"10.1186/s12991-023-00448-z","DOIUrl":"https://doi.org/10.1186/s12991-023-00448-z","url":null,"abstract":"<p><strong>Background: </strong>Coronavirus-19 disease (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Respiratory viruses damage not only the upper respiratory tract in humans, but also several different organs such as the brain. Some of the neurological consequences of COVID-19 reported are anosmia, headache, stroke, declined cognitive function, and impaired mental health, among others. People who had COVID-19 have a higher risk of sequelae in the central nervous system (CNS). However, it is not known which are all possible sequelae and how long will last the long-term effects of the COVID-19 pandemic on behavioral patterns and quality of life.</p><p><strong>Aim: </strong>We intend to address the long-term impacts of COVID-19 on mental health and the relevance of physical exercise during the pandemic.</p><p><strong>Methods: </strong>We conducted a literature search using PubMed to find the articles that were related to these themes.</p><p><strong>Results: </strong>We found 23,489 papers initially, and then we applied the inclusion/exclusion criteria to narrow down our search to 3617 articles and selected 1380 eligible articles after a thorough reading of titles and abstracts. The findings indicated that COVID-19 impacted general mental health and led many not only hospitalized patients to develop cognitive decline, memory impairment, anxiety, sleep alterations, and depressive-like behavior. Furthermore, the fear of vaccines and their effects had negatively affected mental health and directly impacted mortality rates in unvaccinated COVID-19 patients.</p><p><strong>Conclusions: </strong>Preventive measures must be undertaken, such as the vaccination of the entire population, vaccination hesitancy discouragement by creating awareness among individuals, and people's engagement in a physically active lifestyle, since being physically active is a low-cost and effective measure to restore or inhibit the negative outcomes from COVID-19 on mental health.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2023-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9451304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Two clinicians for one patient, is it worth it? Patients' perspective on receiving treatment from a pair of clinicians, in a psychiatric emergency and crisis unit. 一个病人两个医生,值得吗?病人的观点,接受治疗从一对临床医生,在精神科急诊和危机单元。
IF 3.7 3区 医学
Annals of General Psychiatry Pub Date : 2023-04-27 DOI: 10.1186/s12991-023-00446-1
Caroline Dedeystère Pobelov, Orest Weber, Sonia Krenz, Yves Dorogi, Laurent Michaud
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