Annals of African Medicine最新文献

{"title":"Journey from H1N1 to Acute Hemorrhagic Leukoencephalitis.","authors":"K M Srinath, Maneesha Chowdary Bellam, M Basava Chethan, K Nandini","doi":"10.4103/aam.aam_108_24","DOIUrl":"10.4103/aam.aam_108_24","url":null,"abstract":"<p><strong>Abstract: </strong>A diabetic female in her early fifties experienced a 2-day fever, treated with over-the-counter meds. Later, she became less responsive and was hospitalized. On admission, she exhibited irrelevant speech, drowsiness, and neck stiffness. Computed tomography (CT) and magnetic resonance imaging (MRI) scans were initially normal. Meningoencephalitis was suspected and started on empirical antibiotics and antivirals. Her condition declined, causing a seizure and necessitating intubation and mechanical ventilation. A lumbar puncture showed high glucose and protein, but low cell counts in the cerebrospinal fluid. Contrast MRI revealed features of acute hemorrhagic leukoencephalitis. Swab for H1N1 influenza was positive. Treatment with intravenous methylprednisolone, ceftriaxone, acyclovir, and oseltamivir resulted in significant recovery.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Plasma Cholesterol Profile in Sudanese Patients with Hypertension.","authors":"Gad Allah Modawe, Ryan Gesmalla, Nada Mirghani, Reham Mutasem, Fatima Adnan, Awatef Elseddig, Roba Emad, Abdelmarouf Mohieldein","doi":"10.4103/aam.aam_87_24","DOIUrl":"https://doi.org/10.4103/aam.aam_87_24","url":null,"abstract":"<p><strong>Context: </strong>Hypertension (HTN) is a common disease which ultimately leads to mortality from cardiovascular diseases (CVDs).</p><p><strong>Aims: </strong>This study aimed to assess the cholesterol profile among Sudanese patients with HTN in Khartoum State, Sudan.</p><p><strong>Subjects and methods: </strong>A case-control study was conducted in Khartoum State from January 2023 to April 2023. A total of 100 subjects were enrolled in the study: 50 HTN patients as the case group and 50 normotensive individuals as the control group. The plasma cholesterol profile was measured using spectrophotometric methods. The data were analyzed using SPSS.</p><p><strong>Results: </strong>Plasma levels of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) were significantly higher in patients compared to healthy controls (P = 0.000). In contrast, plasma level of high-density lipoprotein cholesterol (HDL-C) was significantly lower in patients than in the control group (P = 0.001). TC was significantly positively correlated with age, systolic blood pressure (SBP), and diastolic blood pressure (DBP) (P = 0.001, P = 0.000, and P = 0.000, respectively). Similarly, plasma LDL-C was significantly positively correlated with SBP, DBP, and age (P = 0.001, P = 0.001, and P = 0.001, respectively). Conversely, plasma HDL-C was significantly negatively correlated with SBP, DBP, age, and body mass index (BMI) (P = 0.000, P = 0.000, P = 0.007, and P = 0.006, respectively).</p><p><strong>Conclusions: </strong>Hypertensive patients showed significantly higher plasma TC and LDL-C but lower HDL-C compared to healthy controls. TC and LDL-C levels significantly positively correlated with age, SBP, and DBP, whereas HDL-C was significantly negatively correlated with SBP, DBP, age, and BMI. Cholesterol management in hypertensive patients reduces the risk for CVDs, a major concern for patients with HTN.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating Megakaryocytes in a Peripheral Blood Smear at the Feathered Edge: An Incidental Finding in a Case of Systemic Inflammatory Response Syndrome.","authors":"Anurag Singh, Akanksha Singh, Ram Nawal Rao","doi":"10.4103/aam.aam_145_24","DOIUrl":"https://doi.org/10.4103/aam.aam_145_24","url":null,"abstract":"<p><strong>Abstract: </strong>Megakaryocytes are large cells with lobulated nuclei found within the bone marrow and comprising 0.01% of all nucleated cells. Circulating megakaryocytes in the peripheral blood smear (PBS) have been rarely described in the literature. We here report a case of a 41-year-old female presented with generalized weakness, high-grade fever (100.8°F), and nausea. Hematology laboratory reports showed anemia and leukocytosis (18.9 × 103/L) with a predominance of neutrophils (95%) and mature megakaryocytes in her PBS at the feathered edge. The laboratory findings of clinical chemistry revealed elevated urea, creatinine, and deranged liver function. This case highlights the rare occurrence of megakaryocytes in the PB of a patient suffering from systemic inflammatory response syndrome. The primary objective of the case study is to gain a better understanding of megakaryocyte biology and its role in the pathogenesis of systemic inflammatory responses.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastric Adenocarcinoma at the Anastomotic Site Three Decades after Gastrojejunostomy: A Case Report with Literature Review.","authors":"Raghav Gupta, Varun Teja Pudota, Prabhat Bhaskarrao Nichkaode","doi":"10.4103/aam.aam_41_25","DOIUrl":"https://doi.org/10.4103/aam.aam_41_25","url":null,"abstract":"<p><strong>Abstract: </strong>Malignancy at the gastrojejunostomy site, though rare, is a recognized long-term risk factor of the procedure. Such malignancies, though uncommon, pose diagnostic and therapeutic challenges. We report a case of a 63-year-old male presenting with a rare complication of gastric carcinoma at the loop gastrojejunostomy site 30 years after surgery for duodenal ulcer-induced gastric outlet obstruction. The patient's symptoms included chronic intermittent upper abdominal pain, postprandial bilious vomiting, significant weight loss, and anorexia. The diagnosis was established through imaging and endoscopic biopsy, revealing a poorly differentiated carcinoma. Following preoperative optimization, the patient underwent subtotal radical gastrectomy with Roux-en-Y reconstruction with D2 lymphadenectomy. Histopathology confirmed poorly cohesive gastric carcinoma (signet ring cell type) with extensive lymph node metastasis (pT4a pN3a M0). Postoperative recovery was uneventful, and the patient was discharged on a CAPEOX regimen for adjuvant chemotherapy. This case highlights the importance of vigilance in patients with long-standing gastrojejunostomy, given the risk of malignancy at the anastomotic site.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human Papillomavirus Vaccine Hesitancy and Barriers in Achieving 100% Vaccine Coverage: A Web-based Cross-sectional Study.","authors":"Asmita Kaundal, Prachi Renjhen, Shikha Sharma, Sonal Prasad, Poojan Dogra Marwaha, Harpreet Kaur","doi":"10.4103/aam.aam_86_24","DOIUrl":"https://doi.org/10.4103/aam.aam_86_24","url":null,"abstract":"<p><strong>Introduction: </strong>The human papillomavirus (HPV) vaccine is one of the most effective primary measures to prevent HPV-related infections and deadly cancers. Despite the availability of the HPV vaccine in the market for almost 17 years, it still remains underutilized. This study is planned with the objective to find out the reasons for vaccine hesitancy (VH) among the Indian population.</p><p><strong>Materials and methods: </strong>Web-based cross-sectional study done using a snowball sampling method. A prevalidated questionnaire containing 15 items was circulated through social media, and responses were evaluated for causes of VH.</p><p><strong>Results: </strong>Out of 1018 study participants, the majority were between 15 and 20 years (64.1%) of age. Most participants were females (60.5% vs. 39.5%). Out of all, 37.8% were sexually active. Most (99%) of the study participants did not have any children. The majority were students (72.2%). Most (87%) had heard about HPV vaccination, and teachers (46.2%) were the most common source of their information. Only 15.4% of the participants were aware that the vaccine was for both boys and girls. Only 15.9% knew that HPV vaccination can protect from genital warts, oropharyngeal carcinoma, cervical cancer, anal cancer, and vulvar and vaginal cancers. The majority (80.9%) were unvaccinated, and unawareness about the vaccine was the most common reason (38.2%) for that. Among vaccinated, majority experienced no major side effects (90.2%).</p><p><strong>Conclusion: </strong>VH is one of the major barriers limiting 100% utilization of HPV vaccine across the country and needs to be addressed to combat the HPV virus-related disease.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness and Attitude of Primary School Teachers toward Absence Seizure in the Eastern Province, Saudi Arabia.","authors":"Rabab Mousa Alhaddad, Nora Isa Almuslim, Thamer Abdullah Alsubaie, Fatimah Ali Albahrani, Fatimah Muhanna Alhubail","doi":"10.4103/aam.aam_116_23","DOIUrl":"https://doi.org/10.4103/aam.aam_116_23","url":null,"abstract":"<p><strong>Objectives: </strong>This research aimed to measure awareness of absence seizures and their effect on academic performance among elementary school teachers in Saudi Arabia's Eastern Province, in addition to measuring their desire to attend awareness-raising workshops that teach them about the disease.</p><p><strong>Methodology: </strong>A cross-sectional study was conducted from August 2022 to March 2023. A total of 509 elementary school teachers in the eastern province of Saudi Arabia completed a self-administrated online questionnaire. The validity and reliability of the questionnaire were established through face validity and a pilot study.</p><p><strong>Results: </strong>The teachers' ages ranged from 20 to more than 50 years (mean: 39.8 ± 11.4 years), and 360 (70.7%) teachers were females. Regarding experience, 139 (27.3%) had worked for <5 years, 111 (21.8%) for 5-10 years, and 259 (50.9%) for more than 10 years. Exact 102 (20%) teachers had overall good knowledge and awareness of absence epilepsy compared to 407 (80%) with an overall poor knowledge level. Four hundred and forty-seven (87.8%) of the teachers agreed that it is important to inform their schools about the child's disease. Exact 483 (94.9%) teachers were willing to learn more about absence epilepsy, and 475 (93.3%) supported the establishment of training courses for teachers to raise awareness of absence epilepsy.</p><p><strong>Conclusion: </strong>Although the vast majority were willing to learn more about absence epilepsy and had a good level of awareness about its effect on academic performance, primary school teachers in Saudi Arabia's Eastern Province demonstrated inadequate knowledge about the disease itself.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To Study the Safety and Efficacy of Fixed Dose Combination of Indacaterolmaleate 110 µg + Glycopyrrinium 50 µg versus Tiotropium 9 µg + Formoterol 12 µg in Patients with Chronic Obstructive Airway Disease.","authors":"Javeeria Shabbir, Imrana Masood, Shah Mohd Abbas Waseem, Syed Yusuf Masood","doi":"10.4103/aam.aam_120_24","DOIUrl":"https://doi.org/10.4103/aam.aam_120_24","url":null,"abstract":"<p><strong>Background: </strong>The efficacy and safety of once-daily fixed-dose combination of indacaterol maleate (IND) 110 μg with glycopyrronium 25 μg (GLY) via Rotahaler device versus tiotropium (TRP) 9 μg + formoterol (FOR) 112 μg was evaluated in patients with chronic obstructive airway disease.</p><p><strong>Objective: </strong>(1) To study and compare the effect of inhaled IND/GLY (110/50 μg) once-daily (OD) fixed-dose combination versus FOR/TRP (9/12 μg) twice daily (BD) on lung function in chronic obstructive pulmonary disease (COPD) patients by evaluating forced expiratory volume in 1 s (FEV1), 1 h postinhalation on days 28th, 56th, and 84th of the treatment. (2) To assess patient-reported outcomes (PROs) using COPD assessment test (CAT) scores, intake of rescue medications, and frequency of exacerbations.</p><p><strong>Materials and methods: </strong>In this prospective observational comparative study, patients were randomly assigned in a 1:1 ratio to two sequences: sequence 1 (n = 50) receiving IND/GLY (110/50 μg) once daily and sequence 2 (n = 50) receiving TRP/FOR (9/12 μg) twice daily. The evaluation of postinhalation FEV1 at 1 h after treatment was conducted on days 28, 56, and 84.</p><p><strong>Result: </strong>Patients in the IND/GLY sequence showed significantly higher FEV1, 1 h postinhalation than those in TRP/FOR. A higher proportion of the patients stated that they were very satisfied with IND/GLY versus TRP/FOR about dyspnea reduction and showed a significant improvement in CAT score. IND/GLY demonstrated a good safety and tolerability profile.</p><p><strong>Conclusion: </strong>This study indicated that, beyond FEV1, important PROs as well as lung function improved with the use of long-acting IND/GLY combination when compared with TRP/FOR.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathogenesis and Current Treatment Strategies in Rheumatoid Arthritis: A Systematic Review Article.","authors":"Debajani Deka","doi":"10.4103/aam.aam_11_24","DOIUrl":"https://doi.org/10.4103/aam.aam_11_24","url":null,"abstract":"<p><strong>Abstract: </strong>Rheumatoid arthritis (RA) is a chronic, symmetrical, and inflammatory autoimmune disease that initially affects small joints, progressing to larger joints, and eventually the skin, eyes, heart, kidneys, and lungs. It has been recorded that RA affects 0.5%-1% of the adult population of developed regions. It initially affects small joints, progressing to larger joints, and eventually the skin, eyes, heart, kidneys, and lungs. Often, the bone and cartilage of joints are destroyed, and tendons and ligaments weaken. All this damage to the joints causes deformities and bone erosion, usually very painful for a patient. RA by producing inflammatory cytokines and proteinases, such as matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases that perpetuate joint destruction by abnormal proliferation of synovium. Under the influence of synovial cells, cytokines such as - Interleukin (IL)-1 and IL-17 chondrocytes are destroyed by apoptosis. Again the extracellular matrix secretes a proteinase called MMPs that damages the type 2 collagen fibers of the cartilage matrix causing biomechanical changes to the joint movements. This way with destruction of articular cartilage of the joint surface by hyperplastic synovium leads to a reduction of joint space. The difference between the hyaline cartilage of the articular surface and other hyaline cartilage is that articular hyaline cartilage never undergoes regeneration. With limited membrane permeability and poor gastrointestinal stability, monoclonal antibodies (mABs) do not have good oral bioavailability (<1%). For this reason, they are usually not administered orally, and parenteral administration is mostly by intravenous, subcutaneous (SC), and intramuscular (IM) injections. When mABs are injected IM or SC, the absorption process from the site of injection is through the interstitial space and into the lymphatic system, with subsequent draining into the systemic circulation. Although IM and SC routes of administration offer lower bioavailability because of proteolytic degradation in the interstitial fluid or the lymphatic system, the SC route is the most widely used due to convenience and the possibility of patient self-administration. For these last two routes of administration, the peak plasma concentration after a single dose is achieved 3-7 days after administration, due to the slow absorption into the systemic circulation. Other potential routes of administration include intravitreal, intraperitoneal, and pulmonary. CRD NUMBER-42024601637.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To Compare the Efficacy of Preoperative Oral 50 g of Maltodextrin versus 50 g of Glucose in Reducing Postoperative Nausea and Vomiting, in Patients Undergoing Laparoscopic Cholecystectomy under General Anesthesia: A Randomized Controlled Double-blind Study.","authors":"Girish Bandigowdanahalli Kumararadhya, Akshay Hiryur Manjunatha Swamy, Darshini Shivaramu, Sonia Jacob, K N Archana, S Vyshnavi","doi":"10.4103/aam.aam_272_24","DOIUrl":"https://doi.org/10.4103/aam.aam_272_24","url":null,"abstract":"<p><strong>Background: </strong>Postoperative nausea and vomiting (PONV) is the second most common complaint following general anesthesia. Despite multimodal strategies to reduce PONV, it still occurs in 20%-30% of patients. Major surgery induces metabolic changes, resulting in insulin resistance. Oral carbohydrate (CHO) loading 2 h before surgery modifies insulin resistance and improves postoperative patient comfort including reduction of PONV.</p><p><strong>Patients and methods: </strong>The present study was a prospective, randomized controlled double-blinded study. 105 patients aged 18-60 years undergoing laparoscopic cholecystectomy under general anesthesia were randomized into three groups: M (50 mg of oral maltodextrin in 100 ml water), G (50 mg of oral glucose in 100 ml water), and C (100 ml of plain water). Each group received the samples 2 h before induction and underwent routine induction and intervention. Their vital parameters were monitored perioperatively and were also evaluated for PONV and perioperative comfort levels.</p><p><strong>Results: </strong>Statistically significant relationship between the groups and postoperative comfort score (χ2 = 34.56, P ≤ 0.001, Cramé's V = 0.41). Analysis of variance test showed difference between the different groups and postextubation General Random Blood Sugar (GRBS) (F = 16.11, P ≤ 0.001). No significant difference was seen among the three groups in preoperative comfort scores (χ2 = 0.72, P = 0.699, Cramé's V = 0.08) and preoperative GRBS (P = 0.055).</p><p><strong>Conclusion: </strong>It was concluded that the oral intake of CHO drink 2 h before surgery improves the comfort of patients by reducing preoperative hunger and thirst along with smaller postoperative glucose spike in the maltodextrin group.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of STOP-BANG and Berlin Questionnaire in the Prediction of Overweight and Obese Patients Developing Desaturation during Induction of General Anesthesia: A Prospective Observational Study.","authors":"Srinivas Hebbal Thammaiah, Akshitha Jayakumar, Rashmi Hosahalli Sreenath, K N Archana, Vyshnavi Sriram","doi":"10.4103/aam.aam_240_24","DOIUrl":"https://doi.org/10.4103/aam.aam_240_24","url":null,"abstract":"<p><strong>Introduction: </strong>Obstructive sleep apnea increases perioperative risk due to compromised airway patency. This study compared the predictive capabilities of the STOP-BANG and Berlin Questionnaires for intraoperative desaturation among overweight and obese patients undergoing general endotracheal anesthesia.</p><p><strong>Aims: </strong>The study primarily aimed to compare desaturation onset time and time to reach 93% oxygen saturation on room air during induction of general anesthesia. Secondary objectives included assessing associated airway complications.</p><p><strong>Settings and design: </strong>A prospective observational study was conducted at a tertiary hospital with overweight and obese patients undergoing elective surgeries under general endotracheal anesthesia.</p><p><strong>Subjects and methods: </strong>Hundred patients aged 18-60 years, body mass index ≥ 25 belonging to the American Society of Anesthesiologists Physical Status Class I-II, divided based on assessment by STOP-BANG (Group S) and Berlin (Group B) Questionnaire participated in the study. Standard anesthesia protocols were followed. SpO2, heart rate, and blood pressure were monitored. Desaturation onset, duration, and airway complications were recorded.</p><p><strong>Statistical analysis used: </strong>Comparisons were made using t-tests and Chi-square tests, with significance set at P < 0.05.</p><p><strong>Results: </strong>Group S had significantly lower SpO2 during induction (P = 0.001) and intubation (P = 0.007), shorter desaturation onset (1.12 vs. 1.55 min, P = 0.00089), and shorter desaturation duration (1.56 vs. 2.21 min, P = 0.013). More patients in Group S required advanced airway equipment (6 vs. 4), and 18% had postoperative desaturation versus none in Group B (P = 0.002). Higher STOP-BANG scores showed stronger correlations with lower SpO2, earlier desaturation onset, longer desaturation periods, and increased airway complications. Conclusions: The STOP-BANG questionnaire is a superior tool for predicting desaturation among overweight and obese patients during induction of general endotracheal anesthesia.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}