Sante (Montrouge, France)最新文献

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[Community-based distribution of injectable contraceptives in an African setting: community trial in Madagascar]. [非洲地区以社区为基础分发注射避孕药具:马达加斯加的社区试验]。
Sante (Montrouge, France) Pub Date : 2011-01-01 DOI: 10.1684/san.2011.0232
Aurélie Brunie, Theresa Hatzell Hoke, Bakolisoa Razafindravony
{"title":"[Community-based distribution of injectable contraceptives in an African setting: community trial in Madagascar].","authors":"Aurélie Brunie,&nbsp;Theresa Hatzell Hoke,&nbsp;Bakolisoa Razafindravony","doi":"10.1684/san.2011.0232","DOIUrl":"https://doi.org/10.1684/san.2011.0232","url":null,"abstract":"<p><p>Community-based distribution of family planning provides a way of reaching underserved populations in developing countries. This article reports findings from an introductory trial of community-based distribution of Depot Medroxyprogesterone Acetate (DMPA), a progestin-only injectable contraceptive. The project, conducted in Madagascar in 2007 in collaboration with the Malagasy government, was intended to test the safety, acceptability, and contribution to policy goals of adding contraceptive injections to the range of methods already offered by paraprofessional community-based health workers in rural areas. In total, 61 agents in 13 communities were trained and initiated service offering DMPA. The intervention was evaluated after 7 months. Data collection included interviews with agents, their supervisors, and a sample of 303 clients, and review of agents' records. In support of the objectives, the descriptive analysis primarily examined the quality of agents' services (safety), three-month reinjection rates (acceptability), and DMPA uptake (contribution). Interviews with agents to test knowledge about correct practices indicated that they are able to provide high quality services. To capture mastery of essential techniques, a composite quality score was calculated from agents' answers. The average score was 23.3 out a maximum possible of 27. All agents scored at least 18 points, and 80% of them received 22 points or more. Interviews with clients further confirmed that agents were competent. The majority of clients were satisfied with the services they received, and a very large proportion (94%) of the women eligible for a second injection received it from the agent. There were no complaints from the communities, and women reported that acceptability among their partners was also high. Finally, the program attracted new users: the 61 agents recruited a total of 1,662 women over six months, 41% of whom were not using family planning when they initiated DMPA. Encouraged by the findings from the pilot project, the Malagasy government has proceeded to expand the program. As of March 2010, a total of 1,109 agents had been trained. At the international level, this study further contributes to the growing body of evidence that well-trained community-based health workers can safely provide injectable contraceptives, potentially helping to increase contraceptive coverage in rural areas with a nationally scaled-up program. While community-based family planning services in Latin America and Asia have included injectables since the 1970s, experiences in sub-Saharan Africa have been very limited. Madagascar was one of the first countries, and several others (Ethiopia, Kenya, Nigeria, Malawi, Rwanda, Uganda, and Zambia) are beginning to include injectables in community-based family planning programs. Furthermore, a recent technical consultation convened by the World Health Organization concluded that global evidence supports the introduction, continuati","PeriodicalId":79375,"journal":{"name":"Sante (Montrouge, France)","volume":"21 1","pages":"21-6"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1684/san.2011.0232","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29864680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
[Lipid profile of patients on chronic hemodialysis (Morocco)]. [慢性血液透析患者血脂(摩洛哥)]。
Sante (Montrouge, France) Pub Date : 2011-01-01 DOI: 10.1684/san.2011.0233
Samira Elmachtani Idrissi, Abdellah Dami, Sanae Bouhsain, Zohra Ouzzif, Toufik Aatif, Mustapha El Mezouari, Mohammed Asseraji, Omar Maoujoud, Mustapha El Allam, Zouhir Oualim, Saida Tellal
{"title":"[Lipid profile of patients on chronic hemodialysis (Morocco)].","authors":"Samira Elmachtani Idrissi,&nbsp;Abdellah Dami,&nbsp;Sanae Bouhsain,&nbsp;Zohra Ouzzif,&nbsp;Toufik Aatif,&nbsp;Mustapha El Mezouari,&nbsp;Mohammed Asseraji,&nbsp;Omar Maoujoud,&nbsp;Mustapha El Allam,&nbsp;Zouhir Oualim,&nbsp;Saida Tellal","doi":"10.1684/san.2011.0233","DOIUrl":"https://doi.org/10.1684/san.2011.0233","url":null,"abstract":"<p><strong>Introduction: </strong>Patients with end-stage renal disease (ESRD) receiving chronic hemodialysis show a high incidence and prevalence of cardiovascular disease of multifactorial etiology and an association between dyslipidemia and accelerated atherosclerosis.</p><p><strong>Objective: </strong>Our aim was to study lipid profiles in ESRD patients receiving dialysis regularly at our hospital (Morocco).Subjects and methods : The patient population consisted of 30 ESRD patients on maintenance haemodialysis. Matched control subjects were recruited among healthy normolipidemic patients. Concentrations of triglycerides (TG), total cholesterol (TC), high-density-lipoprotein cholesterol (HDL-C) and low-density-lipoprotein cholesterol (LDL-C) were measured. The atherogenic index (AI = TC/HDL-C ratio) was calculated.</p><p><strong>Results: </strong>The TG, the HDL-C levels and atherogenic index were significantly higher in groups of hemodialysis patients. We saw no increase in the levels of TC and LDL-C. The prevalence of dyslipidemia in hemodialysis group was high (80%). The most frequent lipid alterations were decreased HDL-C (70%), increased TG (33,3%) and increased LDL-C (23,3%); 50% of ESRD patients have more than two different dyslipidemic findings. AI was higher (≥ 5) in 33,3% of cases.</p><p><strong>Conclusion: </strong>The prevalence of dyslipidemia is higher than normal in ESRD patients on maintenance hemodialysis. Classically, these patients have had low levels of HDL-C and elevated TG levels. Strict control of dyslipidemia should be part of the cardiovascular risk prevention strategy in this population.</p>","PeriodicalId":79375,"journal":{"name":"Sante (Montrouge, France)","volume":"21 1","pages":"27-31"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1684/san.2011.0233","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29959430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Heavy metal in hair samples of 109 non-industrial (miners) population in Katanga. 加丹加省109名非工业(矿工)人口头发样本中的重金属。
Sante (Montrouge, France) Pub Date : 2011-01-01 DOI: 10.1684/san.2011.0229
Myriam Molayi Elenge, Jean-Claude Aubry, Luc Jacob, Christophe De Brouwer
{"title":"Heavy metal in hair samples of 109 non-industrial (miners) population in Katanga.","authors":"Myriam Molayi Elenge,&nbsp;Jean-Claude Aubry,&nbsp;Luc Jacob,&nbsp;Christophe De Brouwer","doi":"10.1684/san.2011.0229","DOIUrl":"https://doi.org/10.1684/san.2011.0229","url":null,"abstract":"<p><strong>Introduction: </strong>This survey aims at proposing reference values of metals in the hair, in the copper-belt (Province of Katanga).</p><p><strong>Materials and methods: </strong>We ran a descriptive study, in an etiologic perspective, on a sample of non-industrial population, constituted by students of the University of Lubumbashi, healthy and without medical treatment (n  = 109). Hair samples were analyzed by Inductively Coupled Plasma Mass Spectrometry (ICP-MS).</p><p><strong>Results: </strong>Twenty metals were identified and quantified: aluminium, antimony, silver, barium, cadmium, calcium, cerium, chromium, cobalt, copper, tin, iron, magnesium, manganese, mercury, molybdenum, nickel, lead, vanadium, and zinc.</p><p><strong>Discussion: </strong>Regarding similar surveys ran upon european no-industrial populations, our results are ranging in the same percentiles. They spread out those percentiles only when our results were too close to quantification limits (silver, tin, mercury, nickel and vanadium). For certain metals, in particular aluminium, cadmium, chromium, cobalt, copper, manganese, molybdenum and lead, we have obtained higher contents. Several reasons can explain this specificity: ICP-MS sensitivity, analysis and preparation technique difference, diet difference or simply public health issues…</p><p><strong>Conclusion: </strong>Our results are close to others surveys' values. They can be validated as reference values for Katanga general population and used to highlight occupational exposure.</p>","PeriodicalId":79375,"journal":{"name":"Sante (Montrouge, France)","volume":"21 1","pages":"41-6"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1684/san.2011.0229","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29960058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
[Factors associated with the quality of well water and the prevalence of waterborne diseases in the municipality of Abomey-Calavi in Benin]. [与贝宁Abomey-Calavi市井水质量和水媒疾病流行有关的因素]。
Sante (Montrouge, France) Pub Date : 2011-01-01 DOI: 10.1684/san.2011.0238
Cyriaque Degbey, Michel Makoutode, Victoire Agueh, Michele Dramaix, Christophe de Brouwer
{"title":"[Factors associated with the quality of well water and the prevalence of waterborne diseases in the municipality of Abomey-Calavi in Benin].","authors":"Cyriaque Degbey,&nbsp;Michel Makoutode,&nbsp;Victoire Agueh,&nbsp;Michele Dramaix,&nbsp;Christophe de Brouwer","doi":"10.1684/san.2011.0238","DOIUrl":"https://doi.org/10.1684/san.2011.0238","url":null,"abstract":"<p><p>The objective of this work is to assess the factors associated with the water quality of household wells, suggest solutions to improve it, and study the prevalence of water-borne diseases in this community. The quality of well water and the prevalence of waterborne diseases in the municipality were studied by analysis of the microbiological indicators currently used to assess drinking-water quality and the retrospective study of waterborne diseases treated in the local health centres. The wells surveyed were contaminated by Escherichia coli, Klebsiella pneumonia, Staphylococcus aureus, Salmonella spp, Clostridium perfringens and fecal streptococci, at prevalences of 12.5, 12.2, 12.2, 12.1, 12 and 11.1%, respectively. The high rates of diarrhea, urinary infections, typhoid fever and abdominal pain found in the retrospective study were consistent with the results of the well-water quality assessment. These results showed that human activity has strongly influenced water quality, especially the lack of sanitation in the different districts and neighbourhoods. Other factors affecting the vulnerability of well water include poor waste management by households, the low depth of the water table, the nature of the soil, and the permeability of the aquifer used. Improvement in water quality, sanitation, and personal hygiene will make it possible to reduce considerably the propagation of these diseases and several others. It is therefore important to provide these populations with the necessary equipment for an adequate drinking water supply, but also to promote health education to avoid water pollution. The search for solutions to these problems will lead to a plan for future action.</p>","PeriodicalId":79375,"journal":{"name":"Sante (Montrouge, France)","volume":"21 1","pages":"47-55"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29959433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
[Prevalence of maternal and placental malaria and of neonatal low birth weight in a semi-urban area of Bamako (Mali)]. [巴马科(马里)半城市地区孕产妇和胎盘疟疾患病率以及新生儿低出生体重]。
Sante (Montrouge, France) Pub Date : 2011-01-01 DOI: 10.1684/san.2011.0234
Aminata Famanta, Mahamadou Diakite, Sory Ibrahim Diawara, Seidina A Diakité, Saibou Doumbia, Karim Traoré, Drissa S Konaté, Mory Doumbia, Abdoul Salam Keita, Daouda Thiéro, Sékou Fantamady Traoré, Seydou Doumbia, Anatole Tounkara
{"title":"[Prevalence of maternal and placental malaria and of neonatal low birth weight in a semi-urban area of Bamako (Mali)].","authors":"Aminata Famanta,&nbsp;Mahamadou Diakite,&nbsp;Sory Ibrahim Diawara,&nbsp;Seidina A Diakité,&nbsp;Saibou Doumbia,&nbsp;Karim Traoré,&nbsp;Drissa S Konaté,&nbsp;Mory Doumbia,&nbsp;Abdoul Salam Keita,&nbsp;Daouda Thiéro,&nbsp;Sékou Fantamady Traoré,&nbsp;Seydou Doumbia,&nbsp;Anatole Tounkara","doi":"10.1684/san.2011.0234","DOIUrl":"https://doi.org/10.1684/san.2011.0234","url":null,"abstract":"<p><p>In 2006, the Malian government established a program for free insecticide-treated net (ITNs) distribution during antenatal care visit (ANC) and intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) for pregnant women. In March to November of 2009, we conducted a cross-sectional study in peri-urban areas of Bamako, Mali to determine the malaria prevalence among pregnant women and their newborn children in the context of this policy. We included 379 pregnant women aged 15 to 45 years. At delivery, malaria was diagnosed using peripheral thick smears in mothers and newborns, as well as umbilical cord blood and placental blood. The prevalence of Plasmodium falciparum malaria was 2.4, 1.6 and 0.5% respectively in mother, placenta and cord samples; we observed a low birth weight rate of 12.1%. Approximately 77% of our parturient were housewives. The illiteracy rate among this group was 72.3%. Of the 379 women, 73% had at least three prenatal visits, 83% had received at least one free ITNs and 72% had received IPTp-SP during antenatal visit. Among them, 81% claimed to have complied with IPTp-SP. No congenital malaria was found. The prevalence of malaria in both mother and newborn has show a significant decrease in Bamako, compared with previous studies before the implementation of IPTp-SP policy in Mali. A high rate of coverage and use of IPTp-SP and ITNs correlate with lower malaria prevalence in pregnant women.</p>","PeriodicalId":79375,"journal":{"name":"Sante (Montrouge, France)","volume":"21 1","pages":"3-7"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1684/san.2011.0234","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29959431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
[Blood supply and demand at the Fifth District Health Centre in Bamako (Mali)]. [巴马科(马里)第五区保健中心的血液供应和需求]。
Sante (Montrouge, France) Pub Date : 2011-01-01 DOI: 10.1684/san.2011.0237
Mamadou Traore, Alexandre Dumont, Amadou Balobo Kaya, Soumana Oumar Traore, Oumar Moussokoro Traore, Amadou Dolo
{"title":"[Blood supply and demand at the Fifth District Health Centre in Bamako (Mali)].","authors":"Mamadou Traore,&nbsp;Alexandre Dumont,&nbsp;Amadou Balobo Kaya,&nbsp;Soumana Oumar Traore,&nbsp;Oumar Moussokoro Traore,&nbsp;Amadou Dolo","doi":"10.1684/san.2011.0237","DOIUrl":"https://doi.org/10.1684/san.2011.0237","url":null,"abstract":"<p><strong>Background: </strong>An adequate uncontaminated blood supply is an essential element of an effective health care system. A regional blood transfusion policy was defined in 2004 by the Direction of Health in Bamako, Mali. The objective of this study is to analyse the coverage of transfusion needs at the Fifth District health Center in Bamako after the implementation of this policy.</p><p><strong>Method: </strong>This prospective study, conducted from December 2006 through May 2007, included 134 patients for whom transfusion orders were recorded in the laboratory. The coverage rate of transfusion needs was estimated by dividing the number of units transfused by the number of units that health professionals requested.</p><p><strong>Results: </strong>The blood supply was regular (46 units per month, on average) and consistent with demand (59 units per month on average). Overall, 75% of the transfusions were required for obstetric complications. All patients received at least one 450-mL unit of whole blood. The coverage of transfusion needs has reached 65% of the total number of units required (95% CI = 60-70%).</p><p><strong>Conclusion: </strong>The implementation of a functioning system of blood transfusion is complex. In Bamako, a system based on a centralized transfusion center met a high proportion of the needs in a reference hospital where demand was high while ensuring a high level of patient safety. Further studies are needed to guide the implementation of feasible and sustainable strategies for providing sufficient quantities of safe blood in other contexts and to assess the impact of these different strategies on global health, and on maternal health in particular.</p>","PeriodicalId":79375,"journal":{"name":"Sante (Montrouge, France)","volume":"21 1","pages":"33-40"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1684/san.2011.0237","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29972020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Pancreatic tuberculosis as a pseudotumor: a case report]. 胰腺结核作为假肿瘤:1例报告。
Sante (Montrouge, France) Pub Date : 2011-01-01 DOI: 10.1684/san.2011.0235
Mountassir Moujahid, Tarik Ziadi, Taoufik Lamsiah, Omar Ouzzad, Ahmed Moudden
{"title":"[Pancreatic tuberculosis as a pseudotumor: a case report].","authors":"Mountassir Moujahid,&nbsp;Tarik Ziadi,&nbsp;Taoufik Lamsiah,&nbsp;Omar Ouzzad,&nbsp;Ahmed Moudden","doi":"10.1684/san.2011.0235","DOIUrl":"https://doi.org/10.1684/san.2011.0235","url":null,"abstract":"<p><p>Tuberculosis is a major public health problem in our country. Abdominal tuberculosis ranks third among the extrapulmonary localisations and account for 3% of the various topographic forms in Morocco. The pancreas and peripancreatic locations are much rarer than peritoneal and intestinal lesions. They present a pseudotumoral appearance that creates a diagnostic emergency. We report a case of pancreatic tuberculosis observed in the general surgery department of the 5th Military Hospital.</p>","PeriodicalId":79375,"journal":{"name":"Sante (Montrouge, France)","volume":"21 1","pages":"61-3"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1684/san.2011.0235","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29959429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Tuberculosis of the breast in a man]. [男性乳房结核]。
Sante (Montrouge, France) Pub Date : 2011-01-01 DOI: 10.1684/san.2011.0236
Mountassir Moujahid, Tarik Ziadi, Taoufik Lamsiah, Omar Ouzzad, H Kechna, Ahmed Moudden
{"title":"[Tuberculosis of the breast in a man].","authors":"Mountassir Moujahid,&nbsp;Tarik Ziadi,&nbsp;Taoufik Lamsiah,&nbsp;Omar Ouzzad,&nbsp;H Kechna,&nbsp;Ahmed Moudden","doi":"10.1684/san.2011.0236","DOIUrl":"https://doi.org/10.1684/san.2011.0236","url":null,"abstract":"<p><p>Tuberculosis is a major public health problem in Morocco. A mammary localisation is very rare. The incidence of tuberculosis remains very low, even in developing countries where it is considered endemic, but the spread of the human immunodeficiency virus has led to an increased number of cases of extrapulmonary tuberculosis, even in the most developed countries. This disease presents essentially diagnostic problems, resolved only by histological and bacteriological study. The treatment is essentially medical, based on antibacterial chemotherapy associated with surgery in some advanced cases.</p>","PeriodicalId":79375,"journal":{"name":"Sante (Montrouge, France)","volume":"21 1","pages":"57-60"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1684/san.2011.0236","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29959432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
[Profile of immunoglobulins A, G, and M during breast milk maturation in a tropical area (Gabon)]. [热带地区(加蓬)母乳成熟期间免疫球蛋白A、G和M的概况]。
Sante (Montrouge, France) Pub Date : 2011-01-01 DOI: 10.1684/san.2011.0230
Félix Ovono Abessolo, Murielle Essomo Owono Megne-Mbo, Simon Ategbo, Marie Andrée N'negue, Elisabeth Lendoye, Régis Mvé Abaga, Serge Békale, Edouard Ngou-Milama
{"title":"[Profile of immunoglobulins A, G, and M during breast milk maturation in a tropical area (Gabon)].","authors":"Félix Ovono Abessolo,&nbsp;Murielle Essomo Owono Megne-Mbo,&nbsp;Simon Ategbo,&nbsp;Marie Andrée N'negue,&nbsp;Elisabeth Lendoye,&nbsp;Régis Mvé Abaga,&nbsp;Serge Békale,&nbsp;Edouard Ngou-Milama","doi":"10.1684/san.2011.0230","DOIUrl":"https://doi.org/10.1684/san.2011.0230","url":null,"abstract":"<p><strong>Objectives: </strong>To study the maturation of breast milk by the course of immunoglobulins A, G and M during the first three weeks of breast feeding.</p><p><strong>Material and methods: </strong>This longitudinal and prospective survey took place from August to October, 2007, in Libreville, the capital of Gabon. The population comprised women with no significant medical history who had given birth in the obstetrics department of Center Hospital of Libreville. Women who delivered at home, had stillbirths, or infants positive for HIV hepatitis B virus were excluded. Three samples were taken, on D1 for colostrum, D7 for the transitional milk and D21 for mature milk. Immunoglobulins were determined by nephelometry, with the Turbox Plus(®) system from Diagnostica Orion. Variables were compared with Spearman's non-parametric test. The survey of the kinetic has been made from the test of Friedman's test was used to assess the kinetics. Significance was set at p<0.05.</p><p><strong>Results: </strong>This survey included 60 mother-child pairs. The mean IgA concentration on D1 was 13.4 ± 5.9 g/L. This concentration fell very quickly by the end of the first week, to 2.3 ± 2.0 g/L on D8, and then stabilized through D21. This rapid drop explains the need for early breast feeding after birth. On the other hand, IgG and IgM concentrations varied less and about one-sixth as high as the IgA. This finding confirms that they were minor components of breast milk.</p><p><strong>Conclusion: </strong>This work shows the importance of the early immune protection provided by the mother to her child during the first week of life.</p>","PeriodicalId":79375,"journal":{"name":"Sante (Montrouge, France)","volume":"21 1","pages":"15-9"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1684/san.2011.0230","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29864685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
[Pregnancy and medical follow-up of women living with HIV/AIDS in Guadeloupe and Martinique (French West Indies): medical progress and social problems]. [瓜德罗普岛和马提尼克岛(法属西印度群岛)感染艾滋病毒/艾滋病妇女的怀孕和医疗后续行动:医疗进步和社会问题]。
Sante (Montrouge, France) Pub Date : 2011-01-01 DOI: 10.1684/san.2011.0231
Dolorès Pourette
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