International journal of fertility and menopausal studies最新文献_第8页

Breast cancer risk among women using silicone gel breast implants. 使用硅胶隆胸的女性患乳腺癌的风险

International journal of fertility and menopausal studies Pub Date : 1995-09-01

D A Edelman, S Grant, W A van Os

引用次数: 0

Menstrual characteristics of women suffering from insulin-dependent diabetes mellitus. 胰岛素依赖型糖尿病患者的月经特征。

International journal of fertility and menopausal studies Pub Date : 1995-09-01

A Yeshaya, R Orvieto, D Dicker, M Karp, Z Ben-Rafael

{"title":"Menstrual characteristics of women suffering from insulin-dependent diabetes mellitus.","authors":"A Yeshaya, R Orvieto, D Dicker, M Karp, Z Ben-Rafael","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To assess the frequency of menarche and menstrual disturbances among women suffering from insulin-dependent diabetes mellitus, and to evaluate their correlation to the onset of diabetes, its duration, and complications.Research design and methods: Retrospective analysis of the menstrual regularity and gynecologic and fertility history of 100 women suffering from insulin-dependent diabetes mellitus. These data were compared with information obtained from the patients' medical records regarding the age at onset of diabetes, its management, control, and complications.Results: The average age at menarche was 13.5 years. Delayed menarche tended to appear in girls whose diabetes was diagnosed before the age of menarche, and before the age of 10 years. Menstrual disturbances, such as oligomenorrhea, amenorrhea, and polymenorrhea, occurred in 32% of the women. A significant correlation was found between late menarche and menstrual disturbances. Furthermore, patients with diabetic complications had a higher incidence of menstrual disorders compared with uncomplicated diabetic patients.Conclusions: It appears that women with insulin-dependent diabetes mellitus who had been diagnosed prior to menarche had a higher probability of delayed menarche, and were at higher risk for development of menstrual disturbances, including amenorrhea with subsequent fertility disorders.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"40 5","pages":"269-73"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19536978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human embryo co-culture: results of a randomized prospective study. 人类胚胎共培养:一项随机前瞻性研究的结果。

International journal of fertility and menopausal studies Pub Date : 1995-09-01

M C Magli, L Gianaroli, A P Ferraretti, D Fortini, A Fiorentino, A D'Errico

引用次数: 0

Hemostatic effects of two oral contraceptives containing low doses of ethinyl estradiol and either gestodene or norgestimate: an open, randomized, parallel-group study. 两种口服避孕药含有低剂量炔雌醇和孕stogene或norgestimate的止血效果:一项开放、随机、平行组研究。

International journal of fertility and menopausal studies Pub Date : 1995-09-01

U H Winkler, C Oberhoff, U Bier, A E Schindler, D Gillain

{"title":"Hemostatic effects of two oral contraceptives containing low doses of ethinyl estradiol and either gestodene or norgestimate: an open, randomized, parallel-group study.","authors":"U H Winkler, C Oberhoff, U Bier, A E Schindler, D Gillain","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To determine effects on blood clotting of two modern low-dose monophasic oral contraceptives.Subjects and methods: We measured in vivo markers of intravascular coagulatory and fibrinolytic activity in 40 volunteers randomly assigned to one of two low-dose oral contraceptives (OCs) for 6 months; one contained 35 micrograms of ethinyl estradiol (EE) plus 250 micrograms of norgestimate and the other, 30 micrograms of EE plus 75 micrograms of gestodene.Results: Both formulations increased coagulatory as well as fibrinolytic activity over baseline: circulating reactive products of thrombin increased by 40%, and plasmin activity by 60%, after 3 months of treatment. Six months of OC use increased hemostatic activity substantially over that with 3 months of use. Differences between both OC formulations were marginal and clinically insignificant.Conclusion: The data suggest an EE-dose-dependent, balanced activation of in vivo coagulation and fibrinolysis in users of currently available, combined OCs. However, there is considerable consumption of coagulation inhibiting factors, suggesting that women with congenital deficiencies of antithrombin III and protein C should not use combined OCs.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"40 5","pages":"260-8"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19536976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonbacterial pyospermia: a consequence of clomiphene citrate therapy. 非细菌性精子症:柠檬酸克罗米芬治疗的结果。

International journal of fertility and menopausal studies Pub Date : 1995-07-01

G J Matthews, M Goldstein, J M Henry, P N Schlegel

{"title":"Nonbacterial pyospermia: a consequence of clomiphene citrate therapy.","authors":"G J Matthews, M Goldstein, J M Henry, P N Schlegel","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Since the development of nonbacterial pyospermia in previously nonpyospermic men treated with clomiphene citrate (CC) has been observed, and nonbacterial prostatitis has been after antiestrogen treatment in an animal model, we sought characterize the occurrence of nonbacterial pyospermia in men treated with CC.Patients and methods: Forty-two nonpyospermic men with low serum testosterone levels treated with 25 mg CC/day were retrospectively compared to 27 untreated nonpyospermic men referred for infertility evaluation.Results: Spontaneous nonbacterial pyospermia developed in CC-treated men [14.3%] at rate nearly twice that observed in controls [7.4%]. Serum testosterone increased in CC-treated men, both pyospermic and nonpyospermic. However, only CC-treated, nonpyospermic men demonstrated improvement in semen characteristics. CC-treated men who developed pyospermia were older than nonpyospermic men [pyospermic, 41.7 +/- 8.1 years; nonpyospermic, 35.6 +/- 4.9 years-P < .01). Men over 35 years of age were over six times as likely to develop pyospermia as men under 35 years of age (P < .05). Eight nonpyospermic, CC-treated men (8/36, 22.2%) have contributed to pregnancies leading to live births, whereas no pyospermic man has done so.Conclusion: These findings support an association between a nonbacterial inflammatory response of the human male reproductive tract and CC treatment. This pyospermia may occur without significant deterioration of semen characteristics and with an appropriate response to treatment in terms of serum testosterone level. Men over the age of 35 are statistically more likely to develop pyospermia with this therapy. Our results suggest that clomiphene citrate-associated pyospermia has a negative effect on male fertility.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"40 4","pages":"187-91"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19502475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect on sperm-immobilizing antibodies on the spontaneous and calcium-ionophore (A23187)-induced acrosome reaction. 精子固定抗体对自发和钙离子载体(A23187)诱导顶体反应的影响。

International journal of fertility and menopausal studies Pub Date : 1995-07-01

I Tasdemir, M Tasdemir, J Fukuda, H Kodama, T Matsui, T Tanaka

{"title":"Effect on sperm-immobilizing antibodies on the spontaneous and calcium-ionophore (A23187)-induced acrosome reaction.","authors":"I Tasdemir, M Tasdemir, J Fukuda, H Kodama, T Matsui, T Tanaka","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To study the effect of sperm-immobilizing antibodies on spontaneous and A23187-induced acrosome reactions.Material and methods: Swim-up spermatozoa obtained from a fertile donor were incubated with 16 sera containing sperm-immobilizing antibodies obtained from infertile women and 3 control sera obtained from healthy females. The acrosome loss, either occurring spontaneously or induced by 10-microM A23181, were examined by staining sperm with Pisum sativum agglutinin labeled with fluorescein isothiocyanate.Results: The incidence of the spontaneous acrosome reaction of spermatozoa incubated with anti-sperm antibodies (6.25 +/- 1.4%) was significantly (P < .001) lower than that of the spermatozoa incubated with control sera (12 +/- 0.8%). The incidence of A23187-induced and inducible (incidence of induced minus spontaneous) acrosome reactions of spermatozoa incubated with sera-positive for sperm antibodies (10.4 +/- 1.3% and 4.2 +/- 1.5%) was also significantly lower (P < .001) than that of spermatozoa incubated with control sera (30.7 +/- 0.5% and 18.7 +/- 1.2%).Conclusion: Sperm immobilizing antibodies interfere with fertilization by inhibiting the acrosome reaction.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"40 4","pages":"192-5"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19502476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conservative management options for cervical pregnancy; case reports and literature review. 宫颈妊娠的保守治疗方案;病例报告及文献回顾。

International journal of fertility and menopausal studies Pub Date : 1995-07-01

M D Creinin, V A Feldstein

{"title":"Conservative management options for cervical pregnancy; case reports and literature review.","authors":"M D Creinin, V A Feldstein","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To describe three cases of cervical pregnancy treated successfully with different conservative methods and review the literature on conservative treatment of cervical pregnancy over the last 30 years.Methods: Three patients treated conservatively for cervical pregnancy are reported. The literature regarding the conservative management of cervical pregnancy since 1965 was compiled using a MEDLINE search for articles published since 1980 and by reviewing the reference lists of published manuscripts.Results: Three cases of cervical pregnancy were successfully treated using methotrexate with leucovorin rescue, methotrexate without leucovorin rescue, and curettage after angiographic embolization of the right hypogastric and left uterine arteries. Review of conservatively managed cases of cervical pregnancy since 1965 indicates that medical management with methotrexate and preoperative angiographic embolization of the uterine blood supply, when appropriate, results in successful treatment without the need for transfusion.Conclusions: Clinical suspicion of cervical pregnancy early in gestation with preoperative diagnosis may safely allow conservative treatment. Different clinical scenarios may preclude or limit which conservative management options are best for each case.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"40 4","pages":"175-86"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19502474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between serum estradiol concentration and IGF-I, IGF-II and IGF-binding proteins in patients with premature ovarian failure on short-term estradiol therapy. 短期雌二醇治疗卵巢早衰患者血清雌二醇浓度与IGF-I、IGF-II及igf结合蛋白的关系

International journal of fertility and menopausal studies Pub Date : 1995-07-01

A N Elias, S C Stone, R Tayyanipour, M R Pandian, F J Rojas, G Gwinup

{"title":"Relationship between serum estradiol concentration and IGF-I, IGF-II and IGF-binding proteins in patients with premature ovarian failure on short-term estradiol therapy.","authors":"A N Elias, S C Stone, R Tayyanipour, M R Pandian, F J Rojas, G Gwinup","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Insulin-like growth factors (IGFs) exert stimulatory effects on follicular growth and development, and early embryogenesis. In view of this, we studied the effect of short-term estradiol treatment, as used in preparing the uterus for embryo implantation, on the serum concentrations of IGFs and their binding proteins (IGFBP) in patients with premature ovarian failure (POF).Patients and methods: Twenty-four patients with POF, enrolled in an assisted reproduction program, were treated with increasing doses of estradiol up to 8 mg daily for 6 weeks. Blood was sampled for measurement of serum estradiol, IGF-I, IGF-II, and IGFBP 1, 2 and 3 at various times during estradiol treatment.Results: There was no significant correlation between serum estradiol concentrations and the serum concentrations of IGF-I and IGF-II. As expected, IGF-I and IGF-II concentrations in serum correlated positively with the serum concentration of IGFBP-3, the major IGF-binding protein in serum.Conclusion: The results of this study suggest that estradiol therapy as used to prepare the uterus for implantation has no significant effect on serum IGF-I and IGF-II concentrations, and therefore probably does not influence, via an IGF-mediated mechanism, the success of implantation and early embryonic development.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"40 4","pages":"196-201"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19502477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A system for simultaneous bilateral tubal cannulation. 同时双侧输卵管插管系统。

International journal of fertility and menopausal studies Pub Date : 1995-07-01

E Confino

{"title":"A system for simultaneous bilateral tubal cannulation.","authors":"E Confino","doi":"","DOIUrl":"","url":null,"abstract":"Objective: The efficacy of a new system for simultaneous bilateral tubal cannulation under tactile impression was evaluated.Methods: Two radiologically detectable selective salpingography catheters (Bard Gynecology and Urology, Covington, GA) were glued back to back in a \"T\" configuration similar to an intrauterine device. A sliding plastic sleeve contained the straightened catheters and the uterus was cannulated under tactile impression. The sleeve was then withdrawn and the catheters opened within the uterine cavity and wedged into the right and left tubal ostia simultaneously. Selective injection of water-soluble radiologic contrast material into the tubes resulted in selective salpingography and determined successful tubal cannulation. Withdrawal of the catheters back into the sleeve allowed injection of contrast material into the uterine cavity.Patients: The system was evaluated in 14 consenting patients scheduled for hysterosalpingogram during infertility evaluation.Results: Bilateral selective salpingography was achieved successfully under tactile impression in 12/14 (86%) patients. In two patients with either distorted or very small uterine cavity, the catheter tips embedded into the lateral uterine walls and did not selectively cannulate the tubal ostia. Reapplication of the system under fluoroscopy allowed bilateral selective salpingography of these two patients.Conclusion: Simultaneous bilateral selective salpingography eliminated the need for cervical cannula, significantly reduced fluoroscopy time to seconds, and demonstrated that tactile cannulation is successful in normal uteri. Application of this system for simultaneous tubal cannulation is identical to intratubal uterine device insertion, a procedure familiar to all gynecologists. Therefore, this catheter system may further contribute to simplification of transcervical access into the fallopian tubes for diagnosis and treatment.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"40 4","pages":"202-5"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19502478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Norethindrone--a review of therapeutic applications. 去甲thindrone——治疗应用综述。

International journal of fertility and menopausal studies Pub Date : 1995-07-01

H F Taitel, M E Kafrissen

引用次数: 0