Annals of Neurosciences最新文献

{"title":"The Psychology of Sexting: How Risk and Nomophobia Intersect.","authors":"Nayana Ratakonda, Durga Rangaswamy Pandian, Darshini Madanagopal, Lakshmi Rajesh, Ayitha Sai Madhumitha","doi":"10.1177/09727531251353055","DOIUrl":"10.1177/09727531251353055","url":null,"abstract":"<p><strong>Background: </strong>Sexting, the explicit sharing of digital content, is found common among young adults in this era. It appears to originate from a process of identity exploration and need for external validation or attention. Social media is used as a tool to validate this need, with easy access to smartphones and impulsivity contributing to its rise.</p><p><strong>Purpose: </strong>Nomophobia, the fear of being separated from one's mobile, has become a significant concern among young adults in today's digital era. This study aimed to examine the psychological and emotional implications of nomophobia, focusing on its relationship with risky decision-making and sexting behaviour.</p><p><strong>Methods: </strong>A sample of 206 young adults aged 18-25 is utilised. Data is collected using self-report questionnaires: the nomophobia questionnaire (NMP-Q), the sexting behaviour scale (SBS) and the domain-specific risk-taking scale (DOSPERT).</p><p><strong>Results: </strong>Linear regression was conducted to evaluate the predictive relationships between risky decision-making, sexting behaviour and nomophobia. Baron and Kenny's mediational analysis examined the role of sexting behaviour as a mediator. Results: This study found that males reported higher levels of risky decision-making (<i>M</i> = 4.03, <0.001) and marginally higher levels of sexting behaviour (<i>M</i> = 1.94, <i>p</i> = .051) compared to females. Regression analysis revealed that risky decision-making significantly predicted nomophobia (<i>β</i> = 0.454, <i>p</i> < .001), while sexting behaviour also emerged as a significant predictor of nomophobia (<i>β</i> = 0.502, <i>p</i> < .001). Baron and Kenny's analysis showed that sexting behaviour partially mediated the relationship between risky decision-making and nomophobia. Risky decision-making significantly predicted nomophobia (<i>β</i> = 0.454), and the indirect effect through sexting behaviour was also significant (<i>β</i> = 0.111).</p><p><strong>Conclusion: </strong>The findings highlight the significant role of risky decision-making and sexting behaviour in predicting nomophobia, with notable gender differences observed in these variables. This study emphasises the need for targeted strategies to address the psychological impact of excessive dependence on mobile devices among young adults.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251353055"},"PeriodicalIF":2.4,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Neuroprotection by Diosgenin and Pterostilbene Combination Against Neurotoxicity Induced by Amyloid-Β 1-42 in SH-SY5Y Differentiated Cell Models.","authors":"Syeda Jabeen Fatima, Devarakonda Krishna Prasad","doi":"10.1177/09727531251356049","DOIUrl":"10.1177/09727531251356049","url":null,"abstract":"<p><strong>Background: </strong>Alzheimer's disease (AD) is the predominant age-related neurodegenerative condition, characterised by the gradual and irreversible loss of neurons. Key pathological features include amyloid plaques and neurofibrillary tangles, which trigger a chronic inflammatory response in the brain, leading to microglial activation and proliferation.</p><p><strong>Purpose: </strong>This study evaluated the neuroprotective potential of diosgenin (DGN) and pterostilbene, two phytoconstituents with known antioxidant and anti-inflammatory properties, in amyloid-β 1-42 exposed SH-SY5Y cells.</p><p><strong>Methods: </strong>Human neuroblastoma cells were cultured and neurodifferentiated with retinoic acid, then exposed to amyloid-β 1-42 to simulate the AD model. Treatments included DGN (1.5 µM), pterostilbene (PTB) (1.5 µM), their combination (0.25 µM and 0.5 µM), and donepezil (1.2 µM) as a standard drug for comparison. The effects of treatments were assessed through cell viability, reactive oxygen species (ROS) levels, apoptosis, inflammatory cytokines, and BDNF levels using various assays, including flow cytometry, ELISA, Western blotting, and inhibitory assays for NOS, H₂O₂-mediated oxidative stress, DPPH, AChE, and β-secretase.</p><p><strong>Results: </strong>DGN and PTB combination indicated increased cell viability, reduced microglial activation, decreased apoptosis, and lower ROS levels, with the maximum effect observed in the combination group (0.5 µM). Combination treatments also showed maximum inhibition in various assays and reduced levels of cytokines while upregulating BDNF, highlighting their neuroprotective, anti-inflammatory, and antioxidant activities.</p><p><strong>Conclusion: </strong>The findings suggest that the combination of DGN and PTB may serve as an effective neuroinflammatory modulator in managing neurodegenerative diseases.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251356049"},"PeriodicalIF":2.4,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12289621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144726606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Exploratory Study on 'Vancharya' as a Therapeutic Approach to the Bio-field of Young Adults Using Electronic Photographic Imaging.","authors":"Madhu Pandey, Kritika Rastogi, Reetika Pal, Chhaya Gupta, Manju Agrawal, Ritu Tripathi Chakravarty, S Z H Zaidi","doi":"10.1177/09727531251340505","DOIUrl":"10.1177/09727531251340505","url":null,"abstract":"<p><strong>Background: </strong>Amid the fast-paced world, nature has a therapeutic modality for healing individuals both physiologically and psychologically. One such practice mentioned in an ancient Indian text is 'Vanacharya', which provides a deep connection with nature and a means of achieving overall well-being. Vancharya is a practice with profound roots in Indian spiritual and philosophical traditions that view the environment as a sacred and valuable source of knowledge and healing.</p><p><strong>Purpose: </strong>This purpose of this experimental research is to explore the therapeutic benefits of 'vancharya', in healing subtle systems of energy or the biofield present within the body like Aura Field (AF), Overall Alignment of Chakra (OAC), Overall, Chakra Energy (OCE), Stress Level (SL), Overall Energy Level (OEL).</p><p><strong>Methods: </strong>This research aims to evaluate the effect of 'vancharya', by examining 50 young adult participants over a one-week period (7 days). The study utilised a non-experimental single-group pre- and post-research design. The data collection was done using an advanced Biowell machine. The obtained data were analysed through a Paired Sample t-test by using SPSS software.</p><p><strong>Results: </strong>The obtained results indicated significant changes in the AF, OAC, OCE, while showing no significant impact on participants' SL and OEL. Subjects also reported improved sleep patterns, less impulsivity, reduced aggression and fewer fluctuations of mood during their sessions in day-to-day activities.</p><p><strong>Conclusion: </strong>Therefore, the research indicates that 'Vancharya' as a therapeutic modality had a significant impact on the subtle systems of energy among young adults. The obtained result from this intervention programme clearly indicates that subtle systems present in the body can have an impact as early as within 7 days itself, whereas, for visible impact within the individual (for instance stress level or overall energy level of the body), the duration of the intervention can be increased.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251340505"},"PeriodicalIF":2.4,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12283605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144706062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Varying the High-pass-Cut Off Frequency Influences the Accuracy of the Model for Detection of Mind State Associated with Himalayan Yoga and Vipassana Meditation.","authors":"Ritu Munjal, Tarun Varshney","doi":"10.1177/09727531251351067","DOIUrl":"10.1177/09727531251351067","url":null,"abstract":"<p><strong>Background: </strong>Meditation and <i>Yoga</i> practices are being adopted and gaining considerable interest as a tool that prevents the occurrence of numerous ailments. Meditation is well prescribed in several old religious manuscripts and has origins in past Indian practices that encourage emotional and personal well-being. Two different classification tasks were performed. One way to identify the mind state allied with <i>Vipassana</i> meditation and another was to identify the mind state allied with <i>Himalayan Yoga</i> meditation. The tasks were performed for classifying non-meditative and meditative states with varying cut-off frequencies to obtain the best results.</p><p><strong>Purpose: </strong>This study is mainly focused on how the high-pass cut-off influences the single-trial accuracy of the model. The performance of the model depends on appropriate pre-processing. The results of High-pass Filter (HPF) at different settings were methodically assessed. Although there are many factors on which the accuracy of the model depends, like the HPF, Independent Components Analysis (ICA), model building and the hyperparameter tuning. One important preprocessing step is to effectively choose the filter to improve the classification results.</p><p><strong>Methods: </strong>Inception Convolutional Gated Recurrent Neural Network (IC-RNN) and Convolutional Neural Network (CNN) models were designed and compared to examine the varying effects of HPF.</p><p><strong>Results and conclusion: </strong>The highest accuracy of 86.19% was attained for IC-RNN, and 99.45% was achieved for CNN model with filter setting at 1 Hz for the <i>Vipassana</i> meditation classification task. The highest accuracy of 88.15% was attained for IC-RNN, and 100% was achieved for CNN model with the same filter setting at 1 Hz for the <i>Himalayan Yoga</i> meditation classification task. HPF at 1 Hz steadily produced good results. Based on the outcomes, the guidelines are suggested for filter settings to increase the performance of the model.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251351067"},"PeriodicalIF":1.8,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144681843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurosteroid Levels in Pregnancy and Its Implications for Mental Health: A Literature Review.","authors":"Kuppan Gokulakrishnan, Viswanathan Mohan, B N Srikumar","doi":"10.1177/09727531251351075","DOIUrl":"10.1177/09727531251351075","url":null,"abstract":"<p><strong>Background: </strong>Perinatal mood disorders are being increasingly recognised and may have deleterious outcomes for the mother and offspring, underlining the importance of understanding their pathophysiology. Neurosteroids can alter the excitability of neurons through rapid non-genomic actions. Here, we review the changes in neurosteroids across pregnancy and their impact on maternal mental health.</p><p><strong>Summary: </strong>Among the neurosteroids, the most studied is allopregnanolone, followed by 5-DHP in pregnancy. Predominantly, allopregnanolone is shown to be increased across pregnancy with a drop in the post-partum levels. With respect to the mood changes in pregnancy and the role of neurosteroids, there are conflicting reports about pregnanolone and its isomers. However, a few studies reported that lower allopregnanolone levels during mid-pregnancy seem to be associated with an increased risk for postpartum depression (PPD).</p><p><strong>Key message: </strong>Thus, while there are reports that have examined individual neurosteroids across pregnancy, studies with serial measurements that include comprehensively all neurosteroids throughout pregnancy and their temporal relationship to mood are needed. Such studies will pave the way for a better understanding of the neurobiology of mood disorders in pregnancy. Additionally, it will facilitate the development of novel antenatal tests for potential predictive biomarkers, thus improving clinical decision-making, patient management and evolving appropriate preventive lifestyle interventions/therapeutic measures.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251351075"},"PeriodicalIF":1.8,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144681841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mindfulness-based Interventions for Emotional Dysregulation in Adolescents: A Systematic Review.","authors":"Nandini Sharma, Manju Agrawal, Rushi, Sayma Ayyub, Divya Rai","doi":"10.1177/09727531251355311","DOIUrl":"10.1177/09727531251355311","url":null,"abstract":"<p><strong>Background: </strong>Emotional dysregulation is a multidimensional construct, understood as frequent and intense experience of emotions combined with a lack of ability to cope with their occurrence. Adolescence represents a crucial developmental period where emotional dysregulation is being increasingly addressed as an emerging mental health issue, with implications on overall well-being, as well as a potential cause of psychopathology. Mindfulness is the awareness that surfaces through purposefully paying attention to the present moment and nonjudgmentally, exploring the layers of moment-to-moment experiences; Mindfulness-Based Interventions (MBIs) emphasise increasing the awareness of the thoughts, feelings, and actions through therapeutic application of Mindfulness techniques. The application of MBIs is conducive to reducing emotional regulation difficulties and has further led to the enhancement of self-regulation of emotions and behaviour.</p><p><strong>Summary: </strong>This study aims to understand the role of MBIs on emotional dysregulation among adolescents.The methodology comprised of a systematic review of literature following the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. The analysis of the literature highlighted that MBIs effectively reduce emotional dysregulation and improve emotional regulation. The findings suggest that MBIs have been found to reduce adolescents' emotional dysregulation and improve emotional regulation, coping skills, as well as neurological functioning, leading to positive outcomes as well as an enhancement of self-regulation of emotions.</p><p><strong>Key messages: </strong>Emotional dysregulation is a critical concern during adolescence and can lead to mental health challenges.Mindfulness-based interventions (MBIs) help enhance emotional awareness and self-regulation.Systematic review findings suggest MBIs effectively reduce emotional dysregulation among adolescents.MBIs can serve as a preventative and therapeutic strategy for adolescent mental health.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251355311"},"PeriodicalIF":1.8,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144681840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial Dysbiosis as an Emerging Pathology of Suicidal Behaviour? A Critical Review, Passing Through Depression to Chronic Pain.","authors":"Alessandra Costanza, Jacques Alexander, Andrea Amerio, Andrea Aguglia, Luca Magnani, Alberto Parise, Daniele Saverino, Gianluca Serafini, Mario Amore, Khoa D Nguyen","doi":"10.1177/09727531251349024","DOIUrl":"10.1177/09727531251349024","url":null,"abstract":"<p><strong>Background: </strong>Suicidal behaviour (SB) is one of the most complex neuropsychiatric conditions, with an etiopathogenesis that remains elusive despite a myriad of studies revealing its multifaceted nature, influenced by various biological, psychological, socioeconomic and cultural factors, usually with complex reciprocal and synergistic interactions. Emerging evidence has recently suggested a potential involvement of pathogens and host-tissue derived microbial species in contributing to SB. This review aims to provide a concise synthesis of clinical evidence focusing on the presence of microbial alterations in subjects with SB and in those exhibiting risk factors for SB, thereby exploring a possible new perspective in suicidology.</p><p><strong>Summary: </strong>We conducted a surveillance of the literature in the PUBMED database, from its inception to 10 May 2025, to identify associations between infection/microbial alterations with SB and some of its risk factors (by focusing on two pathologic examples of psychiatric and somatic origins, respectively: depression and chronic pain, two often closely related conditions). Major clinical findings were selected and synthesised into a hypothetical framework to support the presence of a microbe-related origin of SB. We found that SB was associated with selected infections, such as Toxoplasma gondii and Cytomegalovirus. Dysbiosis, including changes in diversity and/or abundance of selected microbial species, in the oral cavity, gastrointestinal tract, and other mucosal tissues, was observed in subjects with SB and individuals with psychiatric (depression) and somatic (chronic pain) risk factors of SB.</p><p><strong>Key message: </strong>Microbial dysbiosis might contribute to SB etiopathogenesis. Further studies in this emerging field of research are expected to provide additional mechanistic insights for an improved understanding, prevention, and therapeutic management of this neuropsychiatric condition.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251349024"},"PeriodicalIF":1.8,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144681839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nomophobia as an Emerging Psychopathology Psychophysiological Mechanisms and Clinical Implications.","authors":"Saumya Srivastava, Nidhi Verma, Deepak Kumar, Nrashant Singh, Krishan Kumar","doi":"10.1177/09727531251351082","DOIUrl":"10.1177/09727531251351082","url":null,"abstract":"<p><strong>Background: </strong>The phenomenon of anxiety stemming from the absence of a smartphone or mobile device, known as nomophobia, has become increasingly prevalent in contemporary society. This condition is particularly pronounced among young adults and is associated with several adverse psychological outcomes, including depression, anxiety, stress, somatic complaints and anxiety- related disorders.</p><p><strong>Purpose: </strong>This study aims to examine the prevalence of nomophobia and its psychopathological correlations.</p><p><strong>Methods: </strong>The study sample comprised <i>N</i> = 200 college/university students and working adults in the age group of 18-25 years. The Nomophobia Scale, developed by Yildirim and Correia (2015), and the short version of the Personality Assessment Inventory (PAI) by Morey (1991) were employed. The research utilised SPSS-26, a quantitative analysis software, and applied descriptive statistics along with Pearson Product-Moment correlation and simple linear regression.</p><p><strong>Findings: </strong>The results indicated a significant positive correlation between nomophobia and certain subscales of psychological symptoms, such as depression, somatic complaints, anxiety, and anxiety- related disorders. And Nomophobia significantly predicted psychopathologies among young adults.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251351082"},"PeriodicalIF":1.8,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12274209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microglial Dystrophy and Spatial Learning Impairments Following Exposure to Multiple Early-life Stressors in Rats.","authors":"Syed Mujtaba, Nisha Patro, Ishan Kumar Patro","doi":"10.1177/09727531251324716","DOIUrl":"10.1177/09727531251324716","url":null,"abstract":"<p><strong>Background: </strong>Adversities during perinatal critical windows act as a major risk factor for several psychopathologies during adolescence and adulthood. Protein malnutrition, infections, neurotoxicant exposure and social stressors are significant adverse factors encountered by neonates born to socio-economically compromised societies.</p><p><strong>Purpose: </strong>The purpose of this study is to understand how the cumulative exposure to multiple perinatal stressors can result in conditions that mimic various neurological disorders in affected individuals later in life. The present study aimed to understand the involvement of microglia, their activation, priming and dystrophy due to multi-hit exposure in severe spatial learning and memory impairments.</p><p><strong>Methods: </strong>Naïve female Wistar rats (<i>n</i> = 32; 140-150 gm) were divided into control and low protein (LP) groups and fed with 20% and 8% protein diets, respectively, starting from 15 days prior to breeding, followed by mating with healthy males. Pups from both control and LP groups, with their respective mothers, were maintained on their respective diets throughout the experimental regime. Both control and LP F1 Pups were injected intraperitoneally either with deltamethrin (DLT; 0.7 mg/kg body weight) from postnatal day (PND) 1-7 or lipopolysaccharide (LPS; 0.3 mg/kg body weight) at PND3 then a booster on PND5 or both in combination on specified days, forming eight groups: Control, Control+DLT, Control+LPS, Control+DLT+LPS, LP, LP+LPS, LP+DLT and LP+DLT+LPS (Multi-hit). Microglial priming was studied using immunohistochemical procedures, and spatial learning and memory were estimated by the Morris water maze test in F1 rats (1, 3, 6 months).</p><p><strong>Results: </strong>Results revealed that LP F1-treated rats were more susceptible to stressors with reduced brain weight, long-term microglial activation specifying primed states with enhanced expression of CD11b/CR3, MHC-II/OX-6 and ED2.</p><p><strong>Conclusion: </strong>Multi-hit exposure induced dystrophic changes in a large population of microglia, causing severe learning and memory impairments, suggesting that perinatal multi-hit exposure might become a significant risk factor for developmental disorders in adulthood.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251324716"},"PeriodicalIF":1.8,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12274212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender Differences in Quality of Life and Depression Among Post-bariatric Surgery Patients.","authors":"Vidhi Monga, Meenakshi Chauhan","doi":"10.1177/09727531251352630","DOIUrl":"10.1177/09727531251352630","url":null,"abstract":"<p><strong>Background: </strong>Obesity is a significant global health issue, leading to various physical and psychological complications. Bariatric surgery is considered to be an efficient treatment for obesity, contributing to weight loss and metabolic improvements. While the physical benefits of bariatric procedures are well documented, the psychological effects, particularly gender differences in quality of life and depression post-surgery, remain an area of interest in the Indian context.</p><p><strong>Purpose: </strong>The study aims to examine the gender changes in QoL and depression among individuals experienced the Surgery BS. It focuses on three surgical procedures: Roux-en-Y gastric Bypass (RYGB), One Anastomosis Gastric Bypass (OAGB) and sleeve gastrectomy (SG). The study hypothesised that gender differences exist in post-surgical QoL outcomes and depression levels.</p><p><strong>Methods: </strong>A quantitative, cross-sectional research design is employed to assess the gender differences among 200 post-bariatric surgery patients (100 males, 100 females) who had undergone surgery between 3 and 6 months. The equipment that is utilised is the WHOQoL-BREF and even the BDI-II. Hence, the ANOVA and <i>t</i>-tests are even conducted to examine the differences in gender and variations across the process of surgeries.</p><p><strong>Results: </strong>The results outlined that there is no significant difference in depression and Qol among the patients of post-bariatric surgery. The findings even demonstrated that no differences in QoL scores among distinct processes of surgeries among both genders. However, the core trend in depression stages is observed in males based on their surgery type, recommending the possible changes in the outcomes across distinct processes.</p><p><strong>Conclusion: </strong>The results identified no gender-based disparities in QoL and depression following surgery. While RYGB showed slightly higher QoL scores in males while SG exhibited greater levels of depression, these distinctions were not significant. The findings outline the significance of post-operative support for individuals, regardless of type, to enhance mental well-being and QoL.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251352630"},"PeriodicalIF":1.8,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12274327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}