Annals of Neurosciences最新文献

{"title":"Common Yoga Protocol Modulates Traditional Architecture of Personality and Its Association with the Socio-demographic Variables of Prisoners: An Exploratory Study.","authors":"Kalyan Maity, Manjari Rain, Nishant Dixit, Saurabh Kumar, Manish Darmora, Prashant Verma, Swati Kumari Choudhary, Monika Gautam, Kiran Sharma, Amit Singh, Raman Nautiyal, Sanjib Patra, Pooja Nadholta, Krishan Kumar, Vijaya Majumdar, Akshay Anand","doi":"10.1177/09727531251335421","DOIUrl":"https://doi.org/10.1177/09727531251335421","url":null,"abstract":"<p><strong>Background: </strong>Criminal behaviour is influenced by various factors, including social, environmental and individual personality traits. Research has indicated that individuals with psychopathic traits, challenging temperaments and low self-control are more likely to engage in criminal activities. While Yoga has been associated with reducing psychological distress among prison inmates, the application of traditional <i>Vedic</i> philosophy-based personality measures, particularly <i>Triguna</i> (<i>Sattva, Rajas</i> and <i>Tamas</i>), has not been explored within this context.</p><p><strong>Purpose: </strong>This study aimed to explore the effect of the common Yoga protocol (CYP) on <i>Vedic</i> personality traits among prisoners and examine their association with socio-demographic factors.</p><p><strong>Methods: </strong>This exploratory analysis involved a randomised controlled trial with 191 prisoners diagnosed with mild to moderate cognitive impairment, focusing on perceived stress and cognitive improvement. Participants were randomly assigned to either a Yoga group (<i>n</i> = 96) or a control group (<i>n</i> = 95). The Yoga group practiced CYP for two months, while the control group maintained their usual routines. <i>Vedic</i> personality traits were assessed at baseline and post-intervention. A per-protocol analysis was conducted on 88 participants from the Yoga group and 66 from the control group who completed the study.</p><p><strong>Results: </strong>The Yoga group exhibited a significant increase in <i>Sattva</i> (<i>P</i> ≤ .001) and significant decreases in both <i>Rajas</i> (<i>P</i> ≤ .001) and <i>Tamas</i> (<i>P</i> ≤ .001) compared to the control group. Within the Yoga group, <i>Sattva</i> was negatively correlated with age (<i>r</i> = -0.237, <i>P</i> ≤ .05) and BMI (<i>r</i> = -0.220, <i>P</i> ≤ .05), while <i>Tamas</i> was positively correlated with age (<i>r</i> = 0.265, <i>P</i> ≤ .05) and BMI (<i>r</i> = 0.252, <i>P</i> ≤ .05).</p><p><strong>Conclusion: </strong>The CYP effectively enhances the positive attribute, that is, <i>Sattva</i>, while reducing negative attributes, that is, <i>Rajas</i> and <i>Tamas</i> of personality among prisoners. Incorporating Yoga into daily prison routines may serve as an effective rehabilitation tool and improve our understanding of the criminal psychology of inmates.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251335421"},"PeriodicalIF":1.8,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12075168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifestyle Disease Investments and Philanthropy Require Higher Inputs than Infectious Diseases for India and Developed World.","authors":"Saurabh Kumar, H R Nagendra, Akshay Anand","doi":"10.1177/09727531251340500","DOIUrl":"10.1177/09727531251340500","url":null,"abstract":"","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"149-150"},"PeriodicalIF":1.8,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expressed Emotions in Patients with Mild to Moderate Ulcerative Colitis: A Descriptive Study.","authors":"Shaini Suraj, Anand Prakash, Pradeep Patil, Deepa Sangolkar, Nayna Rane","doi":"10.1177/09727531251330071","DOIUrl":"https://doi.org/10.1177/09727531251330071","url":null,"abstract":"<p><strong>Background: </strong>Ulcerative colitis (UC) is an autoimmune disease with phases of relapse and remission. Empirical data shows that expressed emotion (EE) is one of the important stressors which shows a direct association with the recurrence of illness. Though a huge amount of research has been done on mental illness, in this research, it has been used to see how this construct effects people with UC.</p><p><strong>Purpose: </strong>To assess the level of EE among patients with mild-to-moderate UC. It also aims to find whether there is a significant difference among UC patients with respective to demographic variables like age, gender, education, marital status and socio-economic status (SES).</p><p><strong>Methods: </strong>It followed a quantitative approach and descriptive survey research design. The sample size was 100, including both males and females (50 each) in the age group of 30-50 years. The tools used were the family emotional involvement (EI) and criticism scale (FEICS) to quantify the perceived criticism (PC) and EI. Inferential statistics and a chi-square test were used.</p><p><strong>Results: </strong>UC patients showed a mean PC score of 14.87 out of 28 and a mean EI score of 17.24 out of 28. UC patients had a total mean score of 32.11, which depicted high EE. There was no significant association found between the demographic variables in this study and EE.</p><p><strong>Conclusion: </strong>The present findings show that patients with UC show moderate PC but high EI. For UC, the family environment can be improved by better interventions in the form of family counselling and psychoeducation. Fostering coping skills, stress management and effective communication in families will help in emotional regulation among patients of UC.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251330071"},"PeriodicalIF":1.8,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Spectrum of Non-motor Symptoms in Correlation with Quality of Life in Parkinson's Disease and Atypical Parkinsonism: Evidence in Reaching Consensus.","authors":"Madhusudan Tapdia, Anand Kumar, Ajay Kumar Yadav, Varun Kumar Singh, Abhishek Pathak, Rameshwar Nath Chaurasia, Vijaya Nath Mishra, Navneet Kumar Dubey, Neetu Rani Dhiman, Monika Shailesh, Deepika Joshi","doi":"10.1177/09727531251321234","DOIUrl":"https://doi.org/10.1177/09727531251321234","url":null,"abstract":"<p><strong>Background: </strong>Non-motor symptoms (NMS) are frequently overlooked, yet they significantly contribute to the progression of Parkinson's disease (PD) or atypical parkinsonism (AP), which include multiple system atrophy (MSA), progressive supranuclear palsy (PSP). Moreover, discrepancies exist in non-motor symptom scale (NMSS) scores for AP and PD, and no consensus has yet been reached.</p><p><strong>Purpose: </strong>We evaluated and compared the NMS and their association with life quality in patients with AP and PD.</p><p><strong>Methods: </strong>This cross-sectional observational report at a single-centre enrolling 204 patients (155 PD, 49 AP (27 MSA), and 22 PSP) from a tertiary care hospital's movement disorder clinic. We used Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS UPDRS)-III and modified Hoehn and Yahr (H&Y) to compute a motor score and disease severity, respectively. We assessed patients' mental capabilities, such as cognitive impairment, through a Mini-Mental State Examination (MMSE). Meanwhile, the NMSS determined the NMSs. Quality of life (QoL) was estimated by PD Questionnaire-39 (PDQ-39).</p><p><strong>Results: </strong>We observed insignificant differences between the PD and atypical parkinsonian syndrome (APS) groups based on disease duration and gender. Worsened motor disability and disease severity were observed in AP (PSP>MSA) (<i>P</i> < .001). The mean NMSS scores for PD, PSP and MSA were 23.7 ± 27.9, 47.6 ± 41.3 and 65.6 ± 35.5, respectively (<i>P</i> < .05). MSA had a comparatively high score for sexual, cardiovascular and urinary domains, while PSP scored higher for memory/attention domains. In contrast, PD group revealed significantly lower scores for perceptual and sexual domains.</p><p><strong>Conclusion: </strong>Compared to PD, NMS was severe and highly prevalent among AP (MSA > PSP), which could be confirmed through the prevalence of sexual cardiovascular and urinary domains in MSA, while attention and mood/cognition, and sleep in PSP.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251321234"},"PeriodicalIF":1.8,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report of Acute Ischaemic Stroke Associated with T​uberculous Meningitis.","authors":"Harsahaj Singh Wilkhoo, Priyanshi Gundaniya, Harshavardhini Visvanathan, Swastika Chatterjee, Ann Dzagnidze","doi":"10.1177/09727531251322546","DOIUrl":"https://doi.org/10.1177/09727531251322546","url":null,"abstract":"<p><strong>Background: </strong>Tuberculous meningitis (TBM) is a severe form of tuberculosis (TB) that affects the meninges, frequently causing major neurological problems. Timely diagnosis and care are crucial to avoid unfavourable consequences, particularly in vulnerable populations.</p><p><strong>Purpose: </strong>This case report aims to highlight the diagnostic problems and management complications of TBM, especially when combined with rare neurological events such as acute ischaemic stroke (AIS).</p><p><strong>Methods: </strong>An 84-year-old female presented with disorientation, seizures, aphasia and hemiparesis. The initial imaging revealed normotensive hydrocephalus and bilateral delta activity on the electroencephalogram (EEG). Despite anti-fungal treatment, CT imaging revealed widespread inflammatory alterations. Sputum and cerebrospinal fluid (CSF) tests were done and revealed the presence of <i>Mycobacterium tuberculosis</i>. MRI indicated several acute lesions, which are symptomatic of TBM.</p><p><strong>Results: </strong>The patient developed AIS, a relatively rare complication of TBM. Treatment was initiated with a combination of anti-TB drugs and corticosteroids. While corticosteroids reduced inflammation and mortality risk, their potential to contribute to long-term disability was noted as an area of concern.</p><p><strong>Conclusion: </strong>This case underscores the critical role of MRI in the early detection of TBM-related complications. Although corticosteroids improve short-term outcomes, their impact on long-term disability necessitates further research. Effective management strategies tailored to vulnerable populations are essential to improve the prognosis of TBM patients.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251322546"},"PeriodicalIF":1.8,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Exploratory Randomised Trial to Assess the Effect of Nadi Shodhan Pranayama as an Adjunct Versus Standard Non-pharmacological Management in Hypertensives.","authors":"Gauri Mittal, Monika Pathania, Praag Bhardwaj, Minakshi Dhar, Meenakshi Khapre, Sunita Mittal","doi":"10.1177/09727531251318810","DOIUrl":"https://doi.org/10.1177/09727531251318810","url":null,"abstract":"<p><strong>Background: </strong>Nadi shodhan pranayama, which is also known as Anulom-vilom pranayama or alternate nostril breathing, has been demonstrated to elicit a decrease in systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate, owing to its stress-reducing effects. One of the most promising quantitative markers of autonomic activity is heart rate variability (HRV).</p><p><strong>Purpose: </strong>This study was done to study the immediate and long-term effects of 10 minutes of nadi shodhan pranayama, preceded by two minutes of yogic deep abdominal breathing, on blood pressure and other autonomic parameters.</p><p><strong>Methods: </strong>Baseline parameters of BP, HRV, Pittsburgh Sleep Quality Index (PSQI) and Hamilton Anxiety Rating Scale (HAM-A) were measured at first visit. Patients were randomised into test and control groups, and the test group was given intervention. BP and HRV were measured once again immediately after intervention for test subjects. After six weeks, BP, HRV, PSQI and HAM-A were repeated.</p><p><strong>Results: </strong>Immediately after the intervention, the test group showed a significant reduction in SBP, DBP and mean heart rate (MHR) with an increase in R-R interval, standard deviation of the NN interval (SDNN), the square root of the mean squared differences of successive NN intervals and high frequency. At follow-up, the test group had a lower SBP and low frequency/high frequency ratio and a higher SDNN and total power, compared to the control group.</p><p><strong>Conclusion: </strong>The practice of nadi shodhan pranayama, preceded by two minutes of yogic deep abdominal breathing, reduced the systolic and diastolic BP and improved HRV-related autonomic parameters, in patients of hypertension on pharmacological therapy, immediately after 10 minutes of practice and after 10 minutes of daily practice for six weeks.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251318810"},"PeriodicalIF":1.8,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burnout Among Mental Health Professionals in India: A Qualitative Enquiry.","authors":"Swapnil Sinha, Supriya Chaturvedi, Ramya Srivastava, Sakchham Shukla, Shivali Sharma","doi":"10.1177/09727531251327477","DOIUrl":"https://doi.org/10.1177/09727531251327477","url":null,"abstract":"<p><strong>Background: </strong>Burnout poses a significant occupational risk to mental health professionals (MHPs), compromising the quality of care provided to clients and eroding clinicians' overall well-being. There is a dearth of studies examining burnout in MHPs within the Indian context. The unique challenges faced by Indian MHPs necessitate localised research. Context-specific research is vital for grasping the complexities of burnout among Indian MHPs.</p><p><strong>Purpose: </strong>The present study intends to explore three research questions: (a) How do MHPs experience burnout in Indian setting? (b) What are the factors that contribute to burnout among MHPs? (c) What are the strategies used by MHPs to cope with burnout?</p><p><strong>Methods: </strong>To develop an insight about these research questions, the researchers used a semi-structured interview schedule and interviewed eight MHPs (five females and three males; age range: 28-50 years). After acquiring consent from each participant, the interview was audio-recorded and manually transcribed by the researchers. Data were analysed using thematic analysis based on the conceptualisation given by Braun and Clarke.</p><p><strong>Results: </strong>Three major themes were developed: (a) experiences of burnout: being in a bind, (b) facets of burnout: candle burning from both sides and (c) protective factors of burnout: a ray of hope, along with subsequent sub-themes and minor themes.</p><p><strong>Conclusion: </strong>The study significantly enhances the burnout literature by providing contextualised accounts of its effects on diverse MHPs in India. Through in-depth explorations, it sheds new light on burnout among Indian MHPs, sharing their personal stories and offering a rich tapestry of experiences. The data underscore the critical need for prioritising practitioner well-being.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251327477"},"PeriodicalIF":1.8,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11993544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracortical Injection of Okadaic Acid Increases Locomotor Activity and Decreases Anxiety-like Behaviour in Adult Male Rats: Potential Involvement of NMDA Receptor.","authors":"Reena Sarah Jacob, Sowmya Gunasekaran, Mantosh Kumar, Ramakrishnapillai Vyomakesannair Omkumar","doi":"10.1177/09727531251314999","DOIUrl":"https://doi.org/10.1177/09727531251314999","url":null,"abstract":"<p><strong>Background: </strong>Neuronal transmission through the <i>N</i>-methyl-d-aspartate receptor (NMDAR) is a key event in synaptic plasticity and excitotoxicity. The channel properties and biochemical signalling activities of the receptor are regulated by phosphatases such as protein phosphatase 1. While the immediate consequences of NMDAR activation have been reported previously, the long-term behavioural changes remain unclear.</p><p><strong>Purpose: </strong>We attempted to investigate the long-term behavioural effects of <i>N</i>-methyl-d-aspartic acid (NMDA) injection and the role of phosphatases during NMDAR signalling.</p><p><strong>Methods: </strong>NMDAR was activated by stereotaxic injection of NMDA into the prefrontal cortex of adult rats. To elucidate the role of phosphatases in mediating NMDAR signalling and associated animal behaviour, okadaic acid (OA), a phosphatase inhibitor, was administered before NMDA injection. The animals were tested for their general locomotion and cognitive function using behavioural assays.</p><p><strong>Results: </strong>A single injection of NMDA impaired cognition in the long term. Interestingly, intracortical OA injection resulted in increased locomotor activity and decreased anxiety-like behaviour in animals without major cognitive effects.</p><p><strong>Conclusion: </strong>We demonstrate that the inhibition of phosphatases during NMDAR signalling can affect locomotion and anxiety-like behaviour in adult male rats. Our study underscores the potential of modulating phosphatases as a pharmacological target for anxiety disorders.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251314999"},"PeriodicalIF":1.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11985480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EEG Microstates as a Functional Marker of Performance During Emotional Interference.","authors":"Tulika Rajawat, Chaithanya Leon, Simran Kaur, Suriya Prakash Muthukrishnan, Prashant Tayade, Ratna Sharma","doi":"10.1177/09727531251321261","DOIUrl":"10.1177/09727531251321261","url":null,"abstract":"<p><strong>Background: </strong>In order to understand social interactions, integration of emotional valence and semantic information plays a pertinent role. Emotional interference is reflected as a decline in executive function in the presence of emotional stimuli (faces and valenced words). We hypothesise that apart from what we perceive, the intrinsic brain activity may also influence the behavioural outcome.</p><p><strong>Purpose: </strong>We aimed to investigate the role of the pre-stimulus EEG microstate in determining the performance of an individual in an emotional interference task.</p><p><strong>Methods: </strong>Twenty healthy participants performed the emotional interference task, while microstate parameters were derived from single trial 128 channel EEG during correct and error trials.</p><p><strong>Results: </strong>We found that four microstate maps could represent the response accuracy of the preceding behavioural response during emotional interference. The intracranial generators of the pre-trial microstate during emotional interference revealed the areas related to phonological processing (middle temporal and superior temporal gyri), emotional processing (inferior parietal, parahippocampal, transverse temporal gyri), conflict resolution (inferior frontal gyrus and insula) and motor responses (pre-central gyrus).</p><p><strong>Conclusion: </strong>In addition to the valence and semantics of the stimuli, the pre-stimulus microstate may help to determine subsequent performance.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251321261"},"PeriodicalIF":1.8,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11969491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Anapanasati Meditation on Thought Patterns and Subjective Well-being Among Orphan Adolescents.","authors":"Tintisha Basu, Pragyan Dangwal, Mahesh Deokar","doi":"10.1177/09727531251326381","DOIUrl":"10.1177/09727531251326381","url":null,"abstract":"<p><strong>Background: </strong>Over 2000 years old, Anapanasati meditation is the technique of mindful breathing where Anapana is breathing and sati is mindfulness. Anapanasati meditation focuses on training the mind to be sensitive to one or more of the entire body, rupture, pleasure and the mind itself-steadying, satisfying or releasing the mind (Satipathannasutta).</p><p><strong>Purpose: </strong>Mindfulness can be enhanced with the extensive practice of mindfulness meditation. The study was conducted to see the effect of Anapanasati meditation on orphan adolescents.</p><p><strong>Methods: </strong>The total sample size comprised 54 orphan adolescents from the Indian city of Pune, Maharashtra. The population had an equal number of male and female participants. Anapanasati meditation was taught to the adolescents for 3 months. Content analysis was used to analyse the subjective experiences of the individuals over a period of 3 months after inter-coder reliability for the items.</p><p><strong>Results: </strong>Appraisal of others' emotions, emotional regulation, sharing feelings with their peers and a promising future saw a maximum increase after Anapanasati meditation. This content analysis provides valuable insights into the impact of meditation on emotional experiences.</p><p><strong>Conclusion: </strong>While stability is observed in various emotional facets, there are nuanced changes that hint at the transformative potential of meditation, particularly in enhancing self-awareness and regulating negative emotions. These findings contribute to the growing body of knowledge on meditation's psychological effects and underscore the need for further research to explore the intricacies of emotional changes during and after meditation.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251326381"},"PeriodicalIF":1.8,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}