Annals of Neurosciences最新文献

{"title":"Effectiveness of Psychosocial Intervention and Psychoeducation in Improving Psychological Well-being and Cognitive Functioning in Caregivers of Substance Use Issues: A Pilot Study.","authors":"K A Agnes Ashmitha, C N Ram Gopal, O T Sabari Sridhar, Kinjari Kancharla","doi":"10.1177/09727531231185925","DOIUrl":"10.1177/09727531231185925","url":null,"abstract":"<p><strong>Background: </strong>Family caregivers of individuals with substance use disorder (SUD) face significant challenges that can impact their well-being, coping abilities, and cognitive functioning. However, the empowerment of these caregivers often goes unnoticed, highlighting the need for supportive interventions.</p><p><strong>Purpose: </strong>To develop and evaluate the effectiveness of a one-on-one intervention program for family caregivers of SUD patients using pre-test and post-test assessments.</p><p><strong>Methods: </strong>A pilot study was conducted using a randomized controlled trial design with 40 family caregivers of individuals with SUD. Through a lottery method, participants were randomly assigned to either the control or experimental groups, with each group consisting of 20 caregivers. The intervention program consisted of 12 one-on-one sessions. Pre-test and post-test assessments utilized the Ryff Psychological Well-being Scale, Ways of Coping, revised by Lazarus and Folkman, the Hamilton Anxiety Rating Scale, and the Kingston Caregiver Stress Scale. Descriptive and inferential statistics were analyzed using SPSS software.</p><p><strong>Results: </strong>Significant differences were observed between the control and experimental groups in psychological well-being, cognitive functioning, coping, anxiety, and stress (<i>p</i> < .01). The one-on-one intervention program significantly improved well-being and coping skills while reducing anxiety and stress levels. Consequently, the program empowered caregivers and enhanced their psychological resilience in the caregiving process.</p><p><strong>Conclusion: </strong>The findings support the effectiveness of the one-on-one intervention program in enhancing the well-being, coping skills, cognitive functioning, anxiety, and stress levels of family caregivers of individuals with SUD. This intervention program has the potential to empower caregivers and enable them to better cope with the challenges they face in providing care.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46229010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Imperative for a Paradigm Shift in India's Healthcare Workforce.","authors":"Sunil Saini","doi":"10.1177/09727531241271428","DOIUrl":"10.1177/09727531241271428","url":null,"abstract":"","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Level of Self-Objectification among Adolescent Girls from Co-educational Schools and All-Girls Schools: A Comparative Study.","authors":"Mansi Dwivedi, Shivali Sharma, Laxmi Vajpeyi, S Z H Zaidi","doi":"10.1177/09727531231185929","DOIUrl":"10.1177/09727531231185929","url":null,"abstract":"<p><strong>Background: </strong>Indian females have been objectified since time immemorial. The ancient Indian texts and architecture have numerous instances of sexual objectification of females. In the present time, self-objectification in girls is evident from the increasing popularity of apps like Photoshop, the rise in the makeup industry, plastic and cosmetic surgeries, and so on. This is especially relevant for females across the globe and leads to huge negative effects on women's identities.</p><p><strong>Purpose: </strong>The aim of the present study is to assess and compare the levels of body surveillance (self-objectification), body shaming, and control beliefs in adolescent girls from co-educational schools and all-girls schools.</p><p><strong>Methods: </strong>Four hundred adolescent girls from Convent schools in different cities in Uttar Pradesh were included in the study using purposive (homogeneous) sampling based on the inclusion criteria. The Objectified Body Consciousness Scale (OBCS) was used to assess body surveillance (self-objectification), body shaming, and control beliefs.</p><p><strong>Results: </strong>The results of the study revealed that the level of body surveillance (self-objectification) was significantly high among Indian adolescent girls. It was found that all-girls schools had a higher level of body surveillance (self-objectification), body shaming, and control beliefs as compared to adolescent girls from co-educational schools.</p><p><strong>Conclusion: </strong>It can be concluded that the phenomenon of self-objectification has numerous implications for the physical and mental well-being of girls, particularly during their formative years. Healthy behaviors and positive thoughts are the best ways to respect and honor one's body. The research suggests the need for meditation, awareness workshops, and school-level counseling for adolescent girls, especially in all-girls schools.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49464163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Nitric Oxide Modulators in Neuroprotective Effects of Mangiferin in 6-Hydroxydopamine-induced Parkinson's Disease in Rats.","authors":"Prafulla Chandra Tiwari, Manju J Chaudhary, Rishi Pal, Rajendra Nath","doi":"10.1177/09727531231184698","DOIUrl":"10.1177/09727531231184698","url":null,"abstract":"<p><strong>Background: </strong>Parkinson's disease (PD) is typified by inflammation of dopaminergic neurons leading to the release of various inflammatory mediators. These mediators activate the transcription factor NF-κB, which in turn activates inducible nitric oxide synthase (iNOS), leading to increased inflammation.</p><p><strong>Purpose: </strong>This study was intended to study the effect of combination of mangiferin, a specific inhibitor of NF-κB with low-dose nitric oxide (NO) modulators.</p><p><strong>Methods: </strong>A total of eight Wistar rats weighing 200-250 g were used in each group. Stereotactic surgery was performed to induce 6-hydroxydopamine (6-OHDA) lesions. The treatment period extended from day 14 to day 42, during which time behavioral tests were performed to evaluate the effects of mangiferin and its combination with NO modulators. On day 42, the brains of the rats were removed for biochemical and molecular analyzes.</p><p><strong>Results: </strong>Mangiferin significantly improved locomotor activity and decreased inflammatory chemokines levels in rats with 6-OHDA lesions. Mangiferin therapy decreased myeloperoxidase (MPO) levels and reduced oxidative stress. In particular, caspase-3, caspase-9 and COX-2 activities were significantly reduced after the mangiferin treatment. A combination of 45-µg mangiferin and 10-mg/kg L-NAME showed the greatest improvement in locomotor, behavioral, biochemical, and molecular parameters impaired by 6-OHDA.</p><p><strong>Conclusion: </strong>In this study, mangiferin was found to protect rats with 6-OHDA lesions by inhibiting inflammation causing chemokines such as TNF-α and IL-6. Besides, the grouping of iNOS inhibitor L-NAME at a dose of 10 mg/kg with 45-µg mangiferin enhanced the anti-inflammatory and anti-Parkinsonian activity of mangiferin. Consequently, the combination therapy of mangiferin and L-NAME is promising for the treatment of PD. However, clinical trials will be required to evaluate the efficacy of this combination therapy in humans.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41792756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Effect on Cortical Activity in Young Indian Males in Response to \"OM\" Chanting: A High-Density Quantitative Electro-Encephalography Study.","authors":"Manorma Saini, Ankit Gurjar, Suriya Prakash Muthukrishnan, Simran Kaur, Ratna Sharma, Prashant T Tayade","doi":"10.1177/09727531231183219","DOIUrl":"10.1177/09727531231183219","url":null,"abstract":"<p><strong>Background: </strong>Meditation using the \"OM\" mantra is the most widely used practice in India. Though reports have been published about the relaxation effect during both verbal \"OM\" chanting and listening to \"OM\" chanting, there is a paucity of literature concerning the cortical areas activated/deactivated after verbal \"OM\" chanting and listening to \"OM\" chanting using quantitative electro-encephalography (qEEG).</p><p><strong>Purpose: </strong>The objective of this study was to compare the effects of verbal \"OM\" chanting and listening to \"OM\" chanting on cortical sources as compared to baseline, as assessed by qEEG.</p><p><strong>Method: </strong>Twenty adult male subjects with a mean age of 27.5 ± 7.5 years and no past or present history of psychiatric, neurological, or auditory disorders or previous exposure to yoga and meditation were recruited from the undergraduate and postgraduate student population of AIIMS, New Delhi. Subjects were given a paradigm designed using E-prime for both verbal and listening to \"OM\" chanting of 5 min each and a 5-min relaxation period in between the tasks. Electroencephalography recording was done using a 128-channel geodesic sensor net with band-pass filtered at 1-70 Hz, and 20-sec data of eyes-closed condition, post-verbal \"OM\", and post-listening to \"OM\" chanting were segmented and pre-processed. Further, source analysis was performed on the data using standardized low-resolution electromagnetic tomography.</p><p><strong>Result: </strong>The pre (baseline) versus post-verbal \"OM\" (<i>p</i> < .05) and post-listening to \"OM\" (<i>p</i> < .05) chanting showed significant differences in similar cortical areas in both verbal \"OM\" and listening to \"OM\" chanting except the three areas, that is, the orbital gyrus, the rectal gyrus, and the sub-callosal gyrus, which were additionally activated post-listening to \"OM\" chanting. Both verbal and listening to \"OM\" chanting induced activation of similar cortical areas, which were classified as the nodes/hubs of specific resting-state networks (RSNs) such as the attentional network, frontoparietal control network, and default mode network.</p><p><strong>Conclusion: </strong>The study results suggest that \"OM\" chanting could facilitate flexible switching between various RSNs to induce a relaxed state and could improve attention simultaneously.Both verbal and listening to \"OM\" chanting induced common activated areas that are classified into frontoparietal, dorsal attention, and default mode network areas. And it is hypothesized that flexible switching between these RSNs could induce a relaxed state and improve attention simultaneously with the possible role of the frontoparietal network.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45682936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative Functions of the Hypothalamus: Linking Cognition, Emotion and Physiology for Well-being and Adaptability","authors":"Mansi Goel, Aayushi Mittal, Vijaya Raje Jain, Akshay Bharadwaj, Shivani Modi, Gaurav Ahuja, Ankur Jain, Kaushal Kumar","doi":"10.1177/09727531241255492","DOIUrl":"https://doi.org/10.1177/09727531241255492","url":null,"abstract":"The hypothalamus, a small yet crucial neuroanatomical structure, integrates external (e.g., environmental) and internal (e.g., physiological/hormonal) stimuli. This integration governs various physiological processes and influences cognitive, emotional, and behavioral outcomes. It serves as a functional bridge between the nervous and endocrine systems, maintaining homeostasis and coordinating bodily functions. Recent advancements in the neurobiology of the hypothalamus have elucidated its functional map, establishing a causal relationship between its responses—such as respiration, sleep, and stress—and various physiological processes. The hypothalamus facilitates and coordinates these complex processes by processing diverse stimuli, enabling the body to maintain internal balance and respond effectively to external demands. This review delves into the hypothalamus’s intricate connections with cognition, emotion, and physiology, exploring how these interactions promote overall well-being and adaptability. Targeted external stimuli can modulate hypothalamic neuronal activities, impacting the physiological, cognitive, and emotional landscape. The review highlights non-invasive techniques, such as controlled breathing exercises, optimized sleep architecture, and stress management, as potential methods to enhance hypothalamic function. Ultimately, this comprehensive review underscores the multifaceted role of the hypothalamus in integrating signals, maintaining homeostasis, and influencing cognition, emotion, and physiology.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141354751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the Association Between Type 2 Diabetes Mellitus and Cognitive Impairment: A Single-centre Experience","authors":"T. Suvvari, Chandra Shekar Kali","doi":"10.1177/09727531241252327","DOIUrl":"https://doi.org/10.1177/09727531241252327","url":null,"abstract":"The global prevalence of diabetes mellitus has been increasing, leading to a rise in morbidity associated with the disease. While diabetic nephropathy, retinopathy and neuropathy are routinely screened in diabetic patients, the cognitive decline associated with diabetes is often overlooked. The purpose of this study is to investigate the prevalence of cognitive impairment and its associated risk factors among patients with type 2 diabetes mellitus (T2DM). An observational cross-sectional study was conducted for two months. The Montreal Cognitive Assessment (MoCA) test, which consists of 30 questions, was used to assess cognitive function. In-depth clinical history along with glycaemic parameters were collected. The chi-square test was used to find out the association between categorical variables and cognitive impairment. Pearson’s correlation test was performed to determine the correlation between glycaemic parameters and cognitive impairment. A total of 96 patients participated in the study. The mean HbA1c (%) was 9.08 ± 1.73, and the mean MoCA score was 25.14 ± 1.63. Mild cognitive impairment (MCI) was noted in 56% patients. Attention was the most common cognitive domain defect found in all MCI patients—100%. Delayed recall and memory were the second most common cognitive domain defect found—92.5%. Higher HbA1c, high FBS and higher PPBS were found to be statistically associated with MCI. A negative correlation was found between glycaemic parameters (HbA1c, FBS and PPBS levels) and MoCA scores. More than half of our study participants reported mild cognitive impairment. It highlights the need for the implementation of routine cognitive testing for diabetes patients. There is a strong negative correlation between MoCA scores and parameters of glycaemic control; higher levels of HbA1c, FBS, and PPBS are seen in people with a lower MoCA score, indicating mild cognitive impairment. Further studies are needed to evaluate whether improving glucose levels helps in improving cognition or not.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141356167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Broad Autism Phenotype and Gait in Parents of Children With and Without Autism Spectrum Disorder","authors":"Umer Jon Ganai, B. Bhushan, K. S. Venkatesh","doi":"10.1177/09727531241249533","DOIUrl":"https://doi.org/10.1177/09727531241249533","url":null,"abstract":"Autism spectrum disorder (ASD) is a highly heritable neurodevelopmental disorder. Research has shown that parents and relatives of children with ASD often exhibit subthreshold ASD-like characteristics known as broad autism phenotype (BAP) as well as impairments in motor behaviours. The current study aimed to examine the BAP traits and motor behaviours, that is, gait in 44 parents of children with ASD and in 48 parents of typically developing children (TD). The BAP traits were measured using the broad autism phenotype questionnaire (BAPQ), and a low-cost computer vision-based framework was utilised to quantify the gait in children with ASD and their parents and TD children and their parents. The parents of children with ASD consistently displayed significantly higher scores on rigid personality and pragmatic language, however, there were no significant differences between the two group of parents on aloof personality of BAP traits. On gait parameters, the parents of children with ASD had a reduced gait speed in comparison to parents of TD children. There were no meaningful similarities in gait parameters of children with ASD and their parents. These findings support the presence of ASD-like traits in the parents of children with ASD and gait speed as a putative motor endophenotype of ASD.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141369254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amlodipine Attenuates Carrageenan-induced Oxidative Stress Targeting Transsynaptic \u2028Neuronal Damage by Promoting Survival of \u2028Retinal Ganglion Cells in Adult Zebrafish \u2028(Danio rerio)","authors":"Ashirbad Nanda, S. Aparna, Rudra Narayan Sahoo, M. Patri","doi":"10.1177/09727531241246671","DOIUrl":"https://doi.org/10.1177/09727531241246671","url":null,"abstract":"Transsynaptic degeneration of retinal ganglion cells (RGCs) likely plays a role in progressive loss of vision in glaucoma. Carrageenan (Carr), obtained from seaweed (Rhodophyceae), a sulphated polysaccharide extracted from a species of red algae ( Chondrus crispus), is a reversible gel mostly used in eye-drop preparation due to its hydrocolloid nature. But Carr-induced inflammation causing oxidative stress in animals has not yet been evaluated. It was reported that amlodipine (AML) can inhibit inflammatory cytokines by lowering intracellular calcium concentration and increasing antioxidant defences. In this study, we examined the impact of AML administration on Carr-induced oxidative stress, causing free radial–mediated neurodegeneration and behavioural alteration in zebrafish. We aimed to evaluate the behavioural alteration in zebrafish using the novel tank diving test (NTDT) and the light-dark preference test (LDPT) as invaluable tools for analysing visual functions. To understand the role of the antioxidant defence system, oxidative stress biomarkers such as lipid peroxidation and CAT activity were analysed. RGCs of the retina of the eye and neurons of the optical tectum (TeO) in the brain were investigated by histopathological studies. Carr-treated groups swam in random patterns and showed an increased number of transitions and spent more time in alter zones, whereas controls prefer perceived motion. AML significantly attenuates the increased lipid peroxidation level and decreased CAT activity with Carr administration. Histopathological analysis showed an increase in the percentage of pyknotic cell counts after Carr treatment, whereas AML supplementation significantly reduced the pyknotic RGC cell count in the retina and TeO of the brain. Findings showed the effectiveness of AML as an antioxidant and neuroprotective agent by reducing pyckonsis in developmental RGCs and possible repair mechanisms against Carr-induced oxidative stress. This study may be useful to know the underlying mechanisms of weakening and eliminating central neurons for synaptic connections in the visual system of zebrafish.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141376520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical and Psychological Intervention for Indian Adult Patients with Cancer: A Randomised Control Study","authors":"V. Barre, Padmaja G., Suvashisa Rana, Ravi Kumar Saxena, Sujata Satapathy","doi":"10.1177/09727531241244781","DOIUrl":"https://doi.org/10.1177/09727531241244781","url":null,"abstract":"Contemporary cancer care primarily focuses on advanced biomedical treatments, often overlooking the psychological and social challenges associated with the illness (psychosocial factors). This oversight can undermine the efficacy of healthcare and subsequently impact the overall well-being of cancer patients. There is a widespread consensus among medical professionals that psychological factors play a crucial role in the care and treatment of cancer patients. The main aim of this study was to examine the effects of treatment as usual (TAU) and a combined intervention (CI) of TAU and psychological intervention (PI) on stress, coping strategies and quality of life among adult cancer patients. The present study employed a pretest–post-test control group design comprising two groups—Group I (a control group involving TAU only) and Group II (an experimental group involving TAU and PI). In Group I ( n1 = 30), the patients with cancer were randomly selected from a pool of 105 cancer patients from three cancer types, lung cancer (LC), breast cancer (BC) and head/neck cancer (HNC), and were administered only TAU (e.g., surgery, chemotherapy and radiation‑hormonal therapy). In Group II ( n2 = 30), the participants were administered not only the regular TAU but also the PI involving psychoeducation, cognitive-behavioural therapy (CBT) and guided imagery. Three research instruments, namely QSC-R23, Brief Cope Inventory and EORTC QLQ-C30 version 3.0, were used for the present study. The study findings revealed that both TAU and CI resulted in positive outcomes across the measured variables. Notably, there was a decrease in stress levels and an improvement in coping strategies, encompassing problem-focused, emotion-focused and adaptive coping. Furthermore, participants showed a decreased reliance on maladaptive coping strategies and reported an enhanced quality of life, as evidenced by improvements in symptom scales. The study indicated that combining PI with TAU resulted in better outcomes, highlighting the effectiveness of CI (TAU with PI) for cancer patients compared to TAU alone.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140967849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}