Annals of Neurosciences最新文献

{"title":"Prevalence and Predictors of Anxiety and Depression in Indian Patients with \u2028Type 2 Diabetes","authors":"Pramod Tripathi, Baby Sharma, Nidhi Kadam, Mayurika Das Biswas, Diptika Tiwari, Anagha Vyawahare, T. Kathrikolly, Maheshkumar Kuppusamy, Venugopal Vijayakumar","doi":"10.1177/09727531241244569","DOIUrl":"https://doi.org/10.1177/09727531241244569","url":null,"abstract":"Numerous investigations indicate the presence of a reciprocal association between type 2 diabetes (T2D) and a range of mental health conditions. However, research on the factors that contribute to depression and anxiety in T2D patients in India is scarce. The present study aims to identify the prevalence and predictors of depression and anxiety in patients with T2D in India. A cross-sectional study that included 2,730 patients with T2D was conducted at the Freedom from Diabetes Clinic in Pune, India. Anxiety and depression were measured by the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorders-7 (GAD-7) Scale. Binary logistic regression was applied to identify the factors predicting anxiety and depression. The prevalence of depression and anxiety were 20.3% and 17.3%, respectively. The major predictors of anxiety and depression were female gender, obesity, unmarried marital status, poor glycaemic control and the presence of comorbid conditions. This study’s findings highlight a significant prevalence of depression and anxiety among patients with T2D in India, with key predictors including gender, obesity, marital status, glycaemic control and comorbid conditions. These findings highlight the critical need for integrated mental health support in routine diabetes care to manage depression and anxiety.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140967348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Life in Caregivers of Alcohol Use Disorder Patients: Role of Family Functioning \u2028and Social Support","authors":"Hunny Kalra, S. Tung","doi":"10.1177/09727531241246896","DOIUrl":"https://doi.org/10.1177/09727531241246896","url":null,"abstract":"Background: Caring for alcohol use disorder (AUD) patients poses significant challenges, impacting caregivers’ quality of life (QOL) across all the dimensions. Following Lazarus and Folkman’s Transactional Model of Stress and Coping, family functioning (FF) and social support (SS) are crucial coping resources. Purpose: This study aims to explore how FF and SS relate to QOL in caregivers of individuals with AUD, recognising their pivotal role in navigating diverse caregiving-related stressors. Methods: A sample of 128 primary caregivers for AUD patients was collected from two psychiatric hospitals in Amritsar, Punjab. Data were collected using assessment tools, such as the World Health Organization Quality of Life Brief Version (WHOQOL–BREF), Family Assessment Device and PGI Social Support Questionnaire, and were analysed through the Pearson product moment correlation and multiple regression analysis. Results: FF ( r = –0.603) and SS ( r = 0.641) exhibited significant correlations with caregivers’ QOL. Multiple regression analysis confirmed that both FF (β = –0.345) and SS (β = 0.436) significantly predicted QOL among caregivers. Approximately 49% of the variance in QOL was explained by the linear combination of SS and FF. Conclusion: Developing tailored programs is essential to enhance caregivers’ physical, mental, social and environmental well-being. Healthcare professionals should recognise the intricate connections among these dimensions, crafting holistic approaches to nurture a supportive caregiving environment.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Verification of Source Activations in a 3D Brain Model Using ‘CLEVER’ Algorithm for Mental Arithmetic Conditions","authors":"Jeenal Rambhia, Rajendra Sutar","doi":"10.1177/09727531241234727","DOIUrl":"https://doi.org/10.1177/09727531241234727","url":null,"abstract":"Background: Living conditions are becoming challenging day by day. Mental stress on individuals is increasing due to multiple reasons. As mental stress is a major cause of mental illness, it must be detected at the earliest to prevent serious conditions such as depression and anxiety. Purpose: The focus of this study is to detect the exact location of the source which causes such damage. In this article, we analyse the mental conditions of subjects under a workload of performing mental arithmetic calculations for various frequency bands and plot the topography to understand the areas of active potentials. Methods: We propose a Novel Cluster Ensemble Verifier (CLEVER) algorithm, which combines two different techniques: clustering and source localisation. The proposed algorithm is highly efficient in identifying the exact location of the source. It is seen that the topographic plots of the independent component analysis (ICA), which has the maximum percentage of relative variance, correlates to the cluster generated. We are able to give the percentage-wise contribution of every component which is responsible for brain source activation with less time complexity. Results: Out of 72 subjects, in 67 subjects, 299 out of 433 components originate from the occipital and parietal areas of the brain with a maximum power of 43.5 µv 2 . As an example, the relative variance of one component is found to be contributing up to 74.03% to source activations. Clusters show similarity across the subjects in the parietal and occipital areas of the brain. The dataset used for experimentation is EEGMAT from Physionet’s repository. The computation time for the algorithms is 17.6 ± 3.2 minutes. Conclusion: Findings show that during mental arithmetic calculations, both occipital and parietal areas of the brain are involved. As the data is acquired by orally mentioning the mathematical problem, subjects tend to visualise the numbers while finding the solution, which is reflected in the occipital area of the brain. CLEVER algorithm verifies the origin of the activity in the occipital and parietal areas of the brain.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140676568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital Mental Health: Role of Artificial \u2028Intelligence in Psychotherapy","authors":"Sandhya Bhatt","doi":"10.1177/09727531231221612","DOIUrl":"https://doi.org/10.1177/09727531231221612","url":null,"abstract":"Background: It is estimated that 6%–7% of the population suffers from mental disorders. WHO reported that one in four families is likely to have at least one member with a behavioural or mental disorder. Post-pandemic, the world has experienced a huge surge in mental health issues. Unfortunately, not everyone is able to access the available mental health services due to constraints such as lack of financial assistance, living in remote areas, fear of being stigmatised and lack of awareness. The emergence of online mental health services could solve some of these problems, as these are easily accessible to people from anywhere, are cost effective and also reduce the fear of being judged or labelled. Lots of efforts are being made today to integrate artificial intelligence with the traditional form of psychotherapy. The role of chatbots for mental health services in the form of e-therapies has been found to be highly relevant and important. Summary: The present study aims to systematically review the evidence on the use of AI-based methods for treating mental health issues. Overall, 95 studies were extracted using some of the popular databases such as Mendeley, PubM, INFO and DOAJ. The terms used in the search included ‘psychotherapy’, ‘online therapies’, ‘artificial intelligence’ and ‘online counselling’. Finally, after screening, 13 studies were selected based on the eligibility criteria. Most of these studies had employed conversational agents as an intervention. The results obtained showed the significant positive consequences of using AI-based approaches in treating mental health issues. Key Message: The study strongly suggests integrating AI with the traditional form of counselling.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140672854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design, Development and Validation of a Customised Mind–Body Module Towards \u2028Resilience Building and Wellness Promotion","authors":"Haritha Dhanasekar, Arthi Balakrishnan, D. C. Mathangi, Sudhakar Singh","doi":"10.1177/09727531241234411","DOIUrl":"https://doi.org/10.1177/09727531241234411","url":null,"abstract":"Background: In today’s world, developing resilience is crucial for managing stress, preserving mental and emotional health, managing work–life balance, fostering self-growth and good relationships and promoting physical health. Nourishing the mind–body connection, using methods for stress reduction and self-care and incorporating a Mind Body Module can contribute to resilience-building initiatives as well as help in wellness promotion. Purpose: This study aims to design, develop and validate a resilience-building module that incorporates mind–body practices. Method: The existing literature on traditional yoga texts and published scientific studies in the area of mind–body practices was used to build the Mind Body Module. Through this approach, a total of 26 practices were identified based on the strength of evidence. Each of these practices was scored by subject matter experts, and the content validity ratio (CVR) was calculated using Lawshe’s formula for validation. Result: The practices/techniques that scored ≥50% along with those suggested by the experts were grouped, and an eight-week module for resilience building and wellness promotion was developed. Conclusion: The Mind Body Module crafted to foster resilience has brought together the knowledge from the Indian system and the well-being practices from the West in a cogent manner. The module’s viability and effectiveness will be evaluated appropriately.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140693557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autoimmune GFAP Astrocytopathy—Beyond the Known Horizon, India’s First Multifaceted Institutional Experience","authors":"Safwan Ahmed, Vimala Christina Colaco K., S. Kannoth, Fathima Raeesa, Z. Misri, Don G. Mascarenhas, Sindhu Nair","doi":"10.1177/09727531241230213","DOIUrl":"https://doi.org/10.1177/09727531241230213","url":null,"abstract":"Background: Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is an immune-mediated inflammatory disease of the central nervous system, the clinical phenotype of which includes meningoencephalitis, myelitis, optic neuritis, seizures, movement disorders, autonomic dysfunction among others, affecting people across all ages. Due to its recent discovery, there is a paucity of literature on this topic and an absolute lack of Indian case series. Purpose: This study aims to shed light on the variable presentations of anti-GFAP astrocytopathy and review the existing literature on the topic. Methods: This was a retrospective study that included all patients who tested positive in the cerebrospinal fluid(CSF) and/or serum for GFAP immunoglobulin G between February 2023 and August 2023, after obtaining ethical clearance. Relevant clinical, demographic data was collected from the electronic medical records. A descriptive analysis of data was done and the current available literature was reviewed. Results: Our case series included four patients (F:M::3:1) with a median age of 28 years at symptom onset. Two of the cases had a relapsing-remitting disease pattern, while the other two had monophasic illnesses. The clinical spectrum we encountered included ataxia, tremors, myoclonus, seizures, recurrent myelitis, brain stem syndromes, autonomic dysfunction and psychiatric manifestations. All four patients responded remarkably to steroids and two patients are on rituximab therapy. Conclusion: Autoimmune GFAP astrocytopathy encompasses an expanding clinical spectrum and should be considered in the context of myelitis, optic neuritis, ataxia, papillitis, seizures, autonomic dysfunction and movement disorders occurring in isolation or more commonly in varying combinations. Our case series, the first in India, shows a favourable clinical profile and the primary hurdle encountered in all four cases was to establish a diagnosis, further stressing the need for a predictive diagnostic algorithm.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140748124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational Stress Among Middle-Aged Professionals in India.","authors":"Syed Sajid Husain Kazmi, Jyotsana Shukla, Rakesh Kumar Tripathi, S Z H Zaidi","doi":"10.1177/09727531231184299","DOIUrl":"10.1177/09727531231184299","url":null,"abstract":"<p><strong>Background: </strong>Professional world nowadays is very competitive, and surviving the cutthroat competition while sustaining work-related stress and pressure is an important task for employees. Professionals are required to meet daily and monthly objectives and may encounter work-related stressors.</p><p><strong>Purpose: </strong>The study aims to explore occupational stress among middle-aged professionals in the age range of 45-60 years from the marketing, banking, and teaching sectors.</p><p><strong>Methods: </strong>A total sample of 180 consented middle-aged professionals in the age range of 45-60 years from the banking, teaching, and marketing sectors were included in the study using a purposive and snowball sampling technique. Professionals having serious medical or psychiatric conditions and undergoing treatment for the same were excluded. The Occupational Stress Index was administered to assess different types of occupational stressors. The statistical analysis was done using the Statistical Package for Social Sciences version 20 software. A descriptive analysis and a one-way analysis of variance (ANOVA) were used to get meaningful results.</p><p><strong>Results: </strong>Results revealed that 40% of the middle-aged professionals reported experiencing minimal levels of occupational stress, followed by 32.2% experiencing moderate levels and 27.8% experiencing high levels of occupational stress. Additionally, it was found that a significantly higher percentage (91.6%) of banking professionals reported low levels of occupational stress compared to their counterparts. Eighty percent of marketing professionals reported experiencing high levels of occupational stress, whereas a majority (73.3%) of teaching professionals reported moderate levels of occupational stress.</p><p><strong>Conclusion: </strong>Occupational stress with different severity levels is found to be common among middle-aged professionals, which is a risk factor to develop mental health problems and affects well-being. Large-scale primary and secondary interventions are required to manage stress and facilitate professional growth and development in India.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11060131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41266220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study of Reliability and Validity of Constructs of Neuromarketing Among Indian Consumers.","authors":"Shruti Traymbak, Anju Shukla, Mili Dutta","doi":"10.1177/09727531231181868","DOIUrl":"10.1177/09727531231181868","url":null,"abstract":"<p><strong>Background: </strong>Consumer behavior research and neurology are combined in the emerging discipline of neuromarketing. Neuromarketing is considered to be one of emerging field to study how consumer's brain reacts to advertisement and other brand's message by observing brainwave, eye, and skin response. The current study examined the emerging field of constructs of neuromarketing like social, attention, technology, and emotions to examine Indian consumer's buying behavior.</p><p><strong>Purpose: </strong>To study the validity and reliability of constructs of neuromarketing that examines consumer's buying behavior among Indian consumers.</p><p><strong>Methods: </strong>A sample of 191 people of different age groups was considered in the study. A random sampling technique was used for data collection. The self-designed questionnaire used for the measurement of neuromarketing constructs and consumers' buying behavior. The current study applied SPSS and AMOS software to validate the measurement model of neuromarketing.</p><p><strong>Results: </strong>The Kaiser-Meyer-Olkin (KMO) and Bartlett's Test's value is 0.784 and this value confirmed that the sample is adequate for factor analysis. Apart from that, the five constructs of neuromarketing - Attention (A), Social (SC), Technological (T), Emotion (E), and Consumer Buying Behavior (BB) had shown the value of Cronbach's alpha to be more than 0.7. Confirmatory Factor Analysis (CFA) had shown value of average variance explained of each constructs 0.5 and composite reliability more than 0.7 which indicates excellent construct validity of constructs for model formation of neuromarketing. The study also validates measurement research model of neuromarketing on the basis of model fit index (chi-square/df = 3.397, RMSEA = 0.10, GFI = 0.92, and CFI = 0.87).</p><p><strong>Conclusion: </strong>The present study had shown good validity and reliability of constructs of neuromarketing and also proved that marketers can apply these constructs to examine behavior pattern of consumers.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11060134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41745202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Brainstem Auditory Evoked Potentials in Subjects with Family History of Hypertension.","authors":"Dibyodyuti Samaddar, Shivangi Sinha, Raj Shekhar, Samir Kumar Singh, Anita Gupta, Tej Bali Singh","doi":"10.1177/09727531231184680","DOIUrl":"10.1177/09727531231184680","url":null,"abstract":"<p><strong>Background: </strong>Hypertension (HTN) has a genetic predisposition and it also impairs microcirculation, thereby, affecting the well vascularized structures like the brainstem and causing changes in Brainstem Auditory Evoked Potentials (BAEPs).</p><p><strong>Purpose: </strong>To find out the usefulness of BAEPs as a screening tool in apparently healthy individuals with a family history of HTN.</p><p><strong>Methods: </strong>One hundred and ten volunteers, aged 17 to 23 years, were enrolled in the study as participants with proper consent. After excluding the subjects with existing diseases or co-morbidities (e.g. diabetes, HTN, schizophrenia, neuropathy, etc.), those on ototoxic or neurotoxic drugs, a preliminary physical examination was performed, following which BAEPs were recorded with a proper device. Statistical analysis is done with SPSS 2016 software using the chi-square test.</p><p><strong>Results: </strong>A consistent distortion in the inter-peak latency of III-V waves is noted when a family history of HTN is present in either parent or maternal grandparents. Other statistically significant findings are present in V/I% (HTN in mother), wave I (HTN in paternal grandfather), wave III (HTN in maternal grandfather), and inter-peak latency I-V (HTN in maternal grandmother).</p><p><strong>Conclusion: </strong>BAEP may be used as a screening tool in individuals with a family history of HTN with supportive evidence from further studies in the near future.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11060133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45863811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurodevelopmental Disorders: Role of Non-invasive Neuromodulation Therapies.","authors":"Barre Vijaya Prasad, Vaibhav Patil, Krishan K Sony","doi":"10.1177/09727531241245664","DOIUrl":"https://doi.org/10.1177/09727531241245664","url":null,"abstract":"","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11060127/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}