Annals of Neurosciences最新文献

{"title":"Neuro Receptor Signal Detecting and Monitoring Smart Devices for Biological Changes in Cognitive Health Conditions","authors":"Vivek Reddy M, Ganesh Gnk, Rudhresh D, Vaishnavi Parimala T, Gaddam Narasimha Rao","doi":"10.1177/09727531231206888","DOIUrl":"https://doi.org/10.1177/09727531231206888","url":null,"abstract":"Currently, wearable sensors significantly impact health care through continuous monitoring and event prediction. The types and clinical applications of wearable technology for the prevention of mental illnesses, as well as associated health authority rules, are covered in the current review. The technologies behind wearable ECG monitors, biosensors, electronic skin patches, neural interfaces, retinal prosthesis, and smart contact lenses were discussed. We described how sensors will examine neuronal impulses using verified machine-learning algorithms running in real-time. These sensors will closely monitor body signals and demonstrate continuous sensing with wireless functionality. The wearable applications in the following medical fields were covered in our review: sleep, neurology, mental health, anxiety, depression, Parkinson’s disease, epilepsy, seizures, and schizophrenia. These mental health conditions can cause serious issues, even death. Inflammation brought on by mental health problems can worsen hypothalamic-pituitary-adrenal axis dysfunction and interfere with certain neuroregulatory systems such as the neural peptide Y, serotonergic, and cholinergic systems. Severe depressive disorder symptoms are correlated with elevated Interleukin (IL-6) levels. On the basis of previous and present data collected utilizing a variety of sensory modalities, researchers are currently investigating ways to identify or detect the current mental state. This review explores the potential of various mental health monitoring technologies. The types and clinical uses of wearable technology, such as ECG monitors, biosensors, electronic skin patches, brain interfaces, retinal prostheses, and smart contact lenses, were covered in the current review will be beneficial for patients with mental health problems like Alzheimer, epilepsy, dementia. The sensors will closely monitor bodily signals with wireless functionality while using machine learning algorithms to analyse neural impulses in real time.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":"7 12","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139439472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Citrus Odour Produces Resilient Response to Cognitive Load and Enhances Performance in the N-Back Task","authors":"Deep Shikha, P. Ojha, Kamla Kant Shukla, Om Lata Bhagat, A. Dixit","doi":"10.1177/09727531231215556","DOIUrl":"https://doi.org/10.1177/09727531231215556","url":null,"abstract":"Background: Olfactory pathway and limbic system demonstrate a close nexus, which paves common ground for investigating the effects of smell on emotions, cognitive load and autonomic functions. Notably, olfactory stimulation during the administration of cognitive load may interfere with the performance. Purpose: The study is planned to investigate the effect of citrus inhalation on cognitive performance, through psychophysiological assessments. Methods: Thirty male participants were subjected to the cognitive load with the 2-back task in control and experimental sessions. Olfactory stimulation was administered with a pure citrus odour through an aroma diffuser. Electrocardiogram (ECG) for heart rate variability (HRV); photoplethysmography (PPG), and electrodermal activity (EDA) were recorded in experimental and control sessions. Results: Citrus odour significantly improved the performance in 2-back task. A paired t-test revealed that the target correct response numbers and target accuracy were significantly increased with the citrus odour inhalation. The EDA showed a rise in the skin conductance level with the 2-back task that was suppressed with the citrus odour administration. The HRV measures, pNN50, RMSSD, and HF power demonstrated a significant increase in the citrus smell. Conclusion: Importantly, citrus odour produced resilience to cognitive stress due to the cognitive task and it was reflected in the EDA. Olfactory stimulation with citrus improved the scores in the 2-back task performance. Though there was no alteration in the overall variability of cardiac oscillation but there was a conspicuous shift of autonomic balance towards the parasympathetic system with the citrus inhalation. The observed finding advocates the use of citrus odour as a cognitive stress-suppressing measure for cognitive enhancement.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":"62 34","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139385453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Need for E-module-based Validated Yoga Protocol","authors":"R. Padmavathi, K. S. Dhamodhini, K. Maheshkumar, Kantipudi Suvarna Jyothi, Silambanan Santhi","doi":"10.1177/09727531231213471","DOIUrl":"https://doi.org/10.1177/09727531231213471","url":null,"abstract":"","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":"82 12","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139156735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Accuracy of Common Mortality Prognostic Scales in Very Old Patients with Intracerebral Haemorrhage","authors":"Rafael Batista, Marta Pereira, Deise Catamo Vaz, Helena Buque, H. Nzwalo, A. Marreiros","doi":"10.1177/09727531231185200","DOIUrl":"https://doi.org/10.1177/09727531231185200","url":null,"abstract":"Spontaneous intracerebral haemorrhage (SICH) is the most severe form of all stroke types. Stratification of SICH severity is important for group comparisons and treatment decisions. The existing prognostic scores for clinical prediction in SICH have not been specifically validated in the very old (≥75 years). Therefore, we aimed to evaluate the accuracy of different SICH vital prognostic scores in the very old. To compare the short-term accuracy of three vital prognostic scores: Functional Outcome in Patients with Primary Intracerebral Haemorrhage (FUNC), Modified Emergency Department Intracerebral Haemorrhage (mEDICH) and the Intracerebral Haemorrhage Score (‘ICH score’) in patients aged 75 or older. Comparison of the discriminative performance of three SICH prognostic scores in a consecutive case series of patients ≥75 years. The prognostic discrimination was assessed using the area under the receiver operating characteristic curve (AUROC). Additionally, a binary logistic regression was conducted to determine independent prognostic factors associated with mortality. The case-fatality was 40.6%. The AUROC and Younden index for the three scores was as it follows: ‘ICH score’ 0.882 and 0.648; mEDICH 0.867 and 0.571; FUNC 0.802 and 0.519. The main independent risk factors of death were presence of intraventricular extension (OR = 4.000,95% CI= 1.933–8.276), INR value (OR = 2.173, 95% CI = 1.146–4.117), haemorrhage volume (OR = 1.881, 95% CI = 1.029–3.440) and GCS (OR = 0.119, 95% CI = 0.060–0.236) for mEDICH. Haemorrhage volume (OR = 3.020, 95% CI = 1.806–5.050) and GCS (OR = 0.043, 95% CI = 0.013–0.151) for FUNC. Haemorrhage volume (OR = 4.950, 95% CI = 2.249–10.897) and intraventricular haemorrhage (OR = 3.811, 95% CI = 1.833–7.924) for ‘ICH score’. The three scores (‘ICH score’, FUNC and mEDICH) showed an excellent capability of discriminating the group of elderly patients at risk of short-term death. Age per se may not be crucial for accurate discrimination of death in the group of elderly. Instead, the inclusion of available physiological markers of fragility would be more scientifically meaningful than age.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":"47 6","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139161923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changing Horizon in Teaching Profession in India: Issues and Challenges","authors":"Shikha Verma, Mitima Sachdeva, Amita Bajpai","doi":"10.1177/09727531231208290","DOIUrl":"https://doi.org/10.1177/09727531231208290","url":null,"abstract":"Background: The education system is the lifeline of a nation. If the education system is strong and free from issues, the nation will, certainly, progress. Teachers have a key role in nation-building. Their opinions for overcoming the issues and challenges of education in the changing horizon can work as a roadmap to quality education. Purpose: The researcher has surveyed 450 teaching professionals to explore the issues and challenges of the changing horizon for teaching professionals in India. Methods: The researcher has developed a five-point rating scale, after an extensive literature review of regulations and reports of commissions and regulatory bodies. MS Excel 2016 version is used and analysis has been done by finding the frequency of respondents on each point of the rating scale. Then, the results have been interpreted and concluded. Results: The recommendations to overcome the issues and challenges for teaching professionals are also given in the changing horizon in India. Conclusion: Concerned professionals must consider factors including adequate infrastructure, up-to-date curricula, qualified faculty, suitable class sizes, learning materials, financial support and well-planned guidelines for quality education in order to improve education quality. A new teacher education program named as Integrated Teacher Education Programme (ITEP)1 and a reform in educational policy as New Education Policy (2020)2 have begun. All the teaching professionals are hopefully waiting for their implementation. A great future for everyone will undoubtedly result from our work.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":"53 42","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138949599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disruption in Sleep and Circadian Rhythm: A Potential Accelerator in Alzheimer’s Disease Progression","authors":"Abdul Hadi Khan, Ali Abdullah, Muhammad Saqlain Mustafa, Muhammad Abdul Qadeer","doi":"10.1177/09727531231200958","DOIUrl":"https://doi.org/10.1177/09727531231200958","url":null,"abstract":"","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135242934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting Beta-Amyloid Protein with Monoclonal Antibodies: A New Hope for Alzheimer’s Treatment","authors":"Farheen Ashraf, Fatimah Kashif Rasool, Muhammad Musab Nafees Uddin, Mohammad Arham Siddiq, Muhammad Saqlain Mustafa","doi":"10.1177/09727531231190989","DOIUrl":"https://doi.org/10.1177/09727531231190989","url":null,"abstract":"","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135242939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in Prenatal Management of Spina Bifida","authors":"Areej Shakil, Burhanuddin Sohail Rangwala, Tooba Noor, Aimen Waqar Khan, Hussain Sohail Rangwala","doi":"10.1177/09727531231189939","DOIUrl":"https://doi.org/10.1177/09727531231189939","url":null,"abstract":"","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":"8 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135391060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Longitudinal Two-Armed Randomized Controlled Trial Protocol to Evaluate the Efficacy of Yoga on Progression of Disease in Early Parkinson’s Disease","authors":"Parameshwar Some, Vijaya Majumdar, Manjunath N. K., Kuldeep Shetty, Atmakur Snigdha","doi":"10.1177/09727531231198298","DOIUrl":"https://doi.org/10.1177/09727531231198298","url":null,"abstract":"Background Numerous studies have shown that yoga can aid patients with Parkinson’s disease (PD) in managing their motor function, functional mobility, balance, anxiety, and overall quality of life. However, most of the reported research either needed more power or evaluated the results during or after the intervention. Due to the long-standing nature of PD, there are still few longitudinal studies investigating the potential of yoga to decrease the progression of the disease. Purpose We study whether sustained adjunct yoga intervention slows PD progression. Methods Over 18 months, this study will investigate the long-term benefits of yoga-based intervention in Parkinson’s patients. The concept of “intention-to-treat (ITT)” will be employed. From the outpatient clinic of the Swami Vivekananda Yoga Anusandhana Samsthana in India, 160 patients with PD will be chosen. They will then be randomly assigned to either the interventional or control groups (1:1). The adjunct intervention group will participate in 21 daily contact yoga sessions (60 min) at the University Medical Center, followed by continued tele-supervised home practice and at-home self-practice. The effectiveness of the adjunct intervention will be evaluated at four different time points (baseline, 3-, 9-, 12-, and 18-month post-randomization). The primary endpoint will be the difference in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at baseline and after 18 months of intervention. Secondary outcomes will include subscores of MDS-UPDRS I, II, and IV, Parkinson’s Disease Questionnaire (PDQ)-39 scores, treatment adherence, the PDQ-39, the Depression, Anxiety, and Stress Scale-21, and the Scales for Outcomes in PD-Sleep Scale (SCOPA-S). The primary outcome will be analyzed using mixed-effect models for repeated measures, adjusted for covariates as fixed effects. Results The protocol was conceptualized in October 2021 and approved by the Institutional Ethics Committee of SVYASA. Recruitment began in February 2022 and is underway with patient enrollment. Conclusion To our knowledge, this is the first controlled study to examine the long-term effects of yoga as an adjuvant therapy on the progression of PD. Key message This would be the first long-term trial to assess the potential of an adjunct yoga intervention to modulate disease progression in early Parkinson’s patients.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":"68 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135479886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Capital and Work Engagement: Moderating Role of Social Relationships","authors":"Kalyani Biswal, Kailash B. L. Srivastava, Sayed Firoj Alli","doi":"10.1177/09727531231198964","DOIUrl":"https://doi.org/10.1177/09727531231198964","url":null,"abstract":"Background Employees are the real capital of any organisation, and to keep the employees productive and functional, employers need to focus on the psychological capital and social relationship of the employees to keep them engaged in their work. This study examined the emerging field of constructs of psychological and social capital to examine Indian employee’s behaviour. Purpose The purpose of this study is to examine a comprehensive model of the relationship between employees’ psychological capital and work engagement. Furthermore, it examines the moderating effect of social relationships between them. Methods This is a primary survey conducted mainly on the manufacturing industry. A sample of 375 mid- and senior-level executives of different age groups was considered in the study from India’s public and private manufacturing sectors administering a questionnaire survey. A random sampling technique was used for data collection. This study applied SPSS and Amos software to validate the measurement model. Results The results indicate a significant correlation among PsyCap, work engagement, and social relationships. PsyCap and social relationships are positively connected to work engagement. Thus, these results provide preliminary support for our hypotheses. The finding suggests that psychological capital and social relationships positively influence work engagement, and social relationships moderate the association between positive psychological capital and work engagement. It helps employees get better engaged at work. Conclusion Organisations must develop psychological capital to provide resources to employees and share a supportive relationship. Developing and maintaining a supportive relationship for employees and employers is important. In the future, both qualitative research methods and longitudinal data from other sectors can be used to understand the interplay between social and psychological capital for enhancing work engagement. Developing and cultivating positive social relations can help employees utilise their psychological strength to better engage in work.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135480558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}