Optimising Paediatric Brain Mapping with Single-Pulse Transcranial Magnetic Stimulation: A New Protocol and Insights.

IF 1.8 Q4 NEUROSCIENCES

Annals of Neurosciences Pub Date : 2025-06-12 DOI:10.1177/09727531251340157

Rudraksh Banga, Aliya Mufti, Suman Jain, Sheffali Gulati, Kanwal Preet Kochhar, Md Iqbal Alam, Sanjay Wadhwa, Kapil Sikka, Rohit Saxena

{"title":"Optimising Paediatric Brain Mapping with Single-Pulse Transcranial Magnetic Stimulation: A New Protocol and Insights.","authors":"Rudraksh Banga, Aliya Mufti, Suman Jain, Sheffali Gulati, Kanwal Preet Kochhar, Md Iqbal Alam, Sanjay Wadhwa, Kapil Sikka, Rohit Saxena","doi":"10.1177/09727531251340157","DOIUrl":null,"url":null,"abstract":"Background: Single-pulse paradigms of transcranial magnetic stimulation (TMS) have been used to understand cortical excitability and reorganisation.Purpose: This study aims to develop a protocol for mapping of the primary motor cortex (M1) using single-pulse TMS in children.Methods: A 11×11 manual grid was created around the hotspot of abductor pollicis brevis (APB). Motor-evoked potential (MEP) amplitude was recorded from 41 sites around the hotspot of APB and analysed.Results: Maximum MEP amplitude was recorded from the hotspot that reduced as distance increased. Heat maps generated were consistent among the participants.Conclusion: In children, 41 single-pulse TMS stimulations with interstimulus interval of two seconds provide reliable information about motor maps. This procedure will aid in understanding cortical reorganisation in children with neurodevelopmental disorders.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251340157"},"PeriodicalIF":1.8000,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162552/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Neurosciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/09727531251340157","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Single-pulse paradigms of transcranial magnetic stimulation (TMS) have been used to understand cortical excitability and reorganisation.

Purpose: This study aims to develop a protocol for mapping of the primary motor cortex (M1) using single-pulse TMS in children.

Methods: A 11×11 manual grid was created around the hotspot of abductor pollicis brevis (APB). Motor-evoked potential (MEP) amplitude was recorded from 41 sites around the hotspot of APB and analysed.

Results: Maximum MEP amplitude was recorded from the hotspot that reduced as distance increased. Heat maps generated were consistent among the participants.

Conclusion: In children, 41 single-pulse TMS stimulations with interstimulus interval of two seconds provide reliable information about motor maps. This procedure will aid in understanding cortical reorganisation in children with neurodevelopmental disorders.

查看原文本刊更多论文

单脉冲经颅磁刺激优化儿科脑制图：一个新的方案和见解。

背景：单脉冲经颅磁刺激（TMS）已被用于理解皮层的兴奋性和重组。目的：本研究旨在开发一种使用单脉冲TMS绘制儿童初级运动皮层（M1）的方案。方法：在诱拐者短掌（APB）热点周围建立11×11人工网格。在APB热点周围的41个位点记录运动诱发电位（MEP）振幅并进行分析。结果：在热点处记录到最大MEP振幅，随距离增加而减小。生成的热图在参与者中是一致的。结论：41次刺激间隔为2秒的单脉冲TMS刺激可提供可靠的运动图谱信息。这一过程将有助于理解神经发育障碍儿童的皮层重组。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Annals of Neurosciences NEUROSCIENCES-

CiteScore

2.40

自引率

0.00%

发文量