{"title":"单脉冲经颅磁刺激优化儿科脑制图：一个新的方案和见解。","authors":"Rudraksh Banga, Aliya Mufti, Suman Jain, Sheffali Gulati, Kanwal Preet Kochhar, Md Iqbal Alam, Sanjay Wadhwa, Kapil Sikka, Rohit Saxena","doi":"10.1177/09727531251340157","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Single-pulse paradigms of transcranial magnetic stimulation (TMS) have been used to understand cortical excitability and reorganisation.</p><p><strong>Purpose: </strong>This study aims to develop a protocol for mapping of the primary motor cortex (M1) using single-pulse TMS in children.</p><p><strong>Methods: </strong>A 11×11 manual grid was created around the hotspot of abductor pollicis brevis (APB). Motor-evoked potential (MEP) amplitude was recorded from 41 sites around the hotspot of APB and analysed.</p><p><strong>Results: </strong>Maximum MEP amplitude was recorded from the hotspot that reduced as distance increased. Heat maps generated were consistent among the participants.</p><p><strong>Conclusion: </strong>In children, 41 single-pulse TMS stimulations with interstimulus interval of two seconds provide reliable information about motor maps. This procedure will aid in understanding cortical reorganisation in children with neurodevelopmental disorders.</p>","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":" ","pages":"09727531251340157"},"PeriodicalIF":1.8000,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162552/pdf/","citationCount":"0","resultStr":"{\"title\":\"Optimising Paediatric Brain Mapping with Single-Pulse Transcranial Magnetic Stimulation: A New Protocol and Insights.\",\"authors\":\"Rudraksh Banga, Aliya Mufti, Suman Jain, Sheffali Gulati, Kanwal Preet Kochhar, Md Iqbal Alam, Sanjay Wadhwa, Kapil Sikka, Rohit Saxena\",\"doi\":\"10.1177/09727531251340157\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Single-pulse paradigms of transcranial magnetic stimulation (TMS) have been used to understand cortical excitability and reorganisation.</p><p><strong>Purpose: </strong>This study aims to develop a protocol for mapping of the primary motor cortex (M1) using single-pulse TMS in children.</p><p><strong>Methods: </strong>A 11×11 manual grid was created around the hotspot of abductor pollicis brevis (APB). Motor-evoked potential (MEP) amplitude was recorded from 41 sites around the hotspot of APB and analysed.</p><p><strong>Results: </strong>Maximum MEP amplitude was recorded from the hotspot that reduced as distance increased. Heat maps generated were consistent among the participants.</p><p><strong>Conclusion: </strong>In children, 41 single-pulse TMS stimulations with interstimulus interval of two seconds provide reliable information about motor maps. This procedure will aid in understanding cortical reorganisation in children with neurodevelopmental disorders.</p>\",\"PeriodicalId\":7921,\"journal\":{\"name\":\"Annals of Neurosciences\",\"volume\":\" \",\"pages\":\"09727531251340157\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-06-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162552/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Neurosciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/09727531251340157\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Neurosciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/09727531251340157","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
Optimising Paediatric Brain Mapping with Single-Pulse Transcranial Magnetic Stimulation: A New Protocol and Insights.
Background: Single-pulse paradigms of transcranial magnetic stimulation (TMS) have been used to understand cortical excitability and reorganisation.
Purpose: This study aims to develop a protocol for mapping of the primary motor cortex (M1) using single-pulse TMS in children.
Methods: A 11×11 manual grid was created around the hotspot of abductor pollicis brevis (APB). Motor-evoked potential (MEP) amplitude was recorded from 41 sites around the hotspot of APB and analysed.
Results: Maximum MEP amplitude was recorded from the hotspot that reduced as distance increased. Heat maps generated were consistent among the participants.
Conclusion: In children, 41 single-pulse TMS stimulations with interstimulus interval of two seconds provide reliable information about motor maps. This procedure will aid in understanding cortical reorganisation in children with neurodevelopmental disorders.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
