Clinical and experimental hypertension. Part B, Hypertension in pregnancy最新文献_第4页

The effect of essential fatty acid and specific vitamin supplements on vascular sensitivity in the mid-trimester of human pregnancy. 必需脂肪酸和特定维生素补充剂对人类妊娠中期血管敏感性的影响。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309006084

P M O'Brien, F Broughton Pipkin

引用次数: 9

The relationship between posture and plasma catecholamines in the pregnant woman. 孕妇体位与血浆儿茶酚胺的关系。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309006087

I Rabau-Friedman, E Peleg, S Mashiach, T Rosenthal

引用次数: 1

Altered ferrokinetics in toxemia of pregnancy: a possible indicator of decreased red cell survival. 妊娠毒血症的铁动力学改变:红细胞存活降低的可能指标。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309023469

S S Entman, L D Richardson, A P Killam

{"title":"Altered ferrokinetics in toxemia of pregnancy: a possible indicator of decreased red cell survival.","authors":"S S Entman, L D Richardson, A P Killam","doi":"10.3109/10641958309023469","DOIUrl":"https://doi.org/10.3109/10641958309023469","url":null,"abstract":"Serum iron concentration was increased in women with toxemia of pregnancy (mean 135 mcg/dl) compared to normotensive parturients (62 mcg/dl) and chronic hypertensive parturients (72 mcg/dl). Mean iron for eclamptics was 203 mcg/dl; for severe preeclamptics, 137 mcg/dl, independent of hepatic or renal function. Recovery to normal postpartum levels occurred in 1-3 days. Concomitant increase in serum ferritin (mean: 59 ng/ml vs. 19 ng/ml for normals) persisted longer. When hepatocellular injury occurred, mean ferritin increased to 421 ng/ml. Increased iron was independent of transferrin concentration. Serum hemoglobin was detectable in 15 of 25 toxemic patients who had elevated serum iron; only 3 of these patients had clinically significant levels. Serum haptoglobin was significantly decreased in 4 of 25 patients. Reticulocyte count averaged 2.5%, with an average hematocrit of 38%. It is hypothesized that serum iron and ferritin increase in response to catabolism of released hemoglobin. The magnitude of iron increase is greater than could be derived from intravascular hemolysis and suggests an extravascular locus.","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"2 1","pages":"171-8"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958309023469","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17922980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Severe preeclampsia - maternal and fetal outcome. 严重先兆子痫-母体和胎儿的结局。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209139862

T J Beneditti, J K Benedetti, M A Stenchever

引用次数: 13

Response of the renin-aldosterone system and antidiuretic hormone to oral water loading and hypertonic saline infusion during and after pregnancy. 妊娠期间和妊娠后肾素醛固酮系统和抗利尿激素对口服水负荷和高渗生理盐水输注的反应。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209139861

M B Vaklotton, J M Davison, A M Riondel, M D Lindheimer

{"title":"Response of the renin-aldosterone system and antidiuretic hormone to oral water loading and hypertonic saline infusion during and after pregnancy.","authors":"M B Vaklotton, J M Davison, A M Riondel, M D Lindheimer","doi":"10.3109/10641958209139861","DOIUrl":"https://doi.org/10.3109/10641958209139861","url":null,"abstract":"Amongst the man physiological changes in human pregnancy are the sustained stimulation of the renin-angiotensin system and a decreases in plasma osmolality (Posm). In this study the effect osmolar and water loading on the renin-angiotensin system and arginine vasopressin (AVP) secretion has been tested in seven women during the third trimester and again 8-10 weeks after delivery. Pregnant women had markedly increased plasma renin substrate (PRS), plasma renin activity (PRA) and plasma renin concentration (PRC) values as well as aldosterone levels when compared to their post-partum values. Osmolar loading with intravenous infusion of hypertonic saline resulted in a decrease in PRA and aldosterone levels both during and after pregnancy but even at the end of the infusion the pregnant women still had values greater than the pre-infusion levels obtained post-partum. Surprisingly, oral water loading also significantly decreased PRA and aldosterone levels in pregnancy, possibly related to the redistribution of extracellular fluid centrally when the pregnant women were in left lateral recumbency. Despite the decreased basal Posm of pregnancy, urinary AVP increased and decreased appropriately during osmolar and water loading. Exact characterisation of the resetting of the threshold for AVP secretion in pregnancy awaits the development of a reliable radioimmunoassay for the determination of AVP in human pregnancy plasma.","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 2-3","pages":"385-400"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209139861","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17809092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Pregnancy-associated hypertension: interrelationships of volume and blood pressure changes. 妊娠高血压:容积和血压变化的相互关系。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209037179

E D Gallery

{"title":"Pregnancy-associated hypertension: interrelationships of volume and blood pressure changes.","authors":"E D Gallery","doi":"10.3109/10641958209037179","DOIUrl":"https://doi.org/10.3109/10641958209037179","url":null,"abstract":"In normal human pregnancy there is considerable expansion of both plasma volume and total extracellular fluid volume, together with marked diminution of vascular reactivity in response to intravenous infusion of vasopressor agents. Pregnancy-associated hypertension (pre-eclampsia) is characterised by increased vascular reactivity, vasoconstriction and a fall in plasma volume associated with a shift of fluid from intravascular to interstitial fluid space. Direct expansion of plasma volume in patients with pregnancy-associated hypertension leads to partial correction of the abnormalities of volume homeostasis together with a significant fall in blood pressure. Certain forms of antihypertensive therapy also lead to reversal of volume contraction and improvement in cardiac function. This is associated with lowered vascular resistance and improved placental function, leading to improved pregnancy outcome. Although these observations do not elucidate the ultimate cause/causes of pregnancy-associated hypertension, they help to unravel the pathologic mechanisms by which the syndrome causes its effects and to suggest rational paths by which therapeutic endeavours may be expected to benefit mother and fetus.","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 1","pages":"39-47"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209037179","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17817396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

A prospective study of urinary prostaglandins E in women with normal and hypertensive pregnancies. 正常妊娠和高血压妊娠妇女尿前列腺素E的前瞻性研究。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209009625

J M Moutquin, N Leblanc

{"title":"A prospective study of urinary prostaglandins E in women with normal and hypertensive pregnancies.","authors":"J M Moutquin, N Leblanc","doi":"10.3109/10641958209009625","DOIUrl":"https://doi.org/10.3109/10641958209009625","url":null,"abstract":"Studies in vitro suggest that pregnancy induced hypertension, or toxemia, is associated with decreased placental prostaglandins E (PGE) levels. To validate this observation in vivo PGE were measured weekly in 24h urine collections, in a prospective cross-sectional study in 9 women from 7 to 40 weeks. In addition, urinary PGE levels were also measured in 28 hospitalized pregnant women with either chronic hypertension or toxemia. Prostaglandins E were measured by radioimmunoassay after organic extraction and silicic acid separation. Urinary PGE levels during pregnancy (normotensive and chronic hypertensive women) were significantly elevated than those of the non-pregnant state. Mean urinary PGE levels in toxemic patients were significantly decreased compared to those of normal pregnancy and patients with chronic hypertension but they were similar to the mean levels of the non-pregnant state. One fetal death attributed to aggravation of chronic hypertension and one eclampsia were associated with undetectable levels of maternal urinary PGE. In conclusion, normal pregnancy is associated with a significant increase of urinary PGE; chronic hypertension and occurrence of toxemia are associated with significant diminution of urinary PGE excretion.","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 4","pages":"539-52"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209009625","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17942557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Renin angiotensin aldosterone system and adrenergic system in normotensive and hypertensive pregnancy. 正常妊娠和高血压妊娠中的肾素、血管紧张素、醛固酮系统和肾上腺素能系统。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209009620

B Coevoet, P Fievet, E Comoy, F Legrand, R Makdassi, P Verhoest, J C Boulanger, A Fournier

{"title":"Renin angiotensin aldosterone system and adrenergic system in normotensive and hypertensive pregnancy.","authors":"B Coevoet, P Fievet, E Comoy, F Legrand, R Makdassi, P Verhoest, J C Boulanger, A Fournier","doi":"10.3109/10641958209009620","DOIUrl":"https://doi.org/10.3109/10641958209009620","url":null,"abstract":"We have measured simultaneously plasma renin activity (PRA), aldosterone and catecholamines in the plasma of 3 groups of pregnant women after the 20th week: group 1 of 16 normotensive controls, group II of 17 women with rest responding hypertension (RRH), group III of 18 women with permanent hypertension (PIH). All the patients were ambulatory on a normal salt diet. PRA was significantly higher in the RRH than in the control and PIH groups (15,8 +/- 2,3ng/ml/l versus 6,7 +/- 0,5 and 8,9 +/- 0,9 respectively). Plasma epinephrine (PE) and norepinephrine (PNE) were significantly higher in the PIH than in the control and RRH groups (respectively 135 +/- 28 pg/ml versus 56 +/- 13 and 63 +/- 17 for PE and 387 +/- 91 versus 206 +/- 32 and 200 +/- 47 pg/ml for PNE). In the PIH group there was a negative correlation between PRA and blood uric acid. It is concluded that the adrenic system is activated in PIH whereas the renin angiotensin system is activated in RRH of pregnancy.","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 4","pages":"479-91"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209009620","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17814475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Maternal mortality in eclampsia in the Guinea Savannah region of Nigeria. 尼日利亚几内亚萨凡纳地区子痫的孕产妇死亡率。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209009624

C C Ekwempu

引用次数: 1

The effect of prostaglandin E1 on the pressor response to angiotensin II in second trimester human pregnancy and in the non-pregnant subject. 前列腺素E1对人类妊娠中期和非妊娠受试者血管紧张素II升压反应的影响。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209009621

F Broughton Pipkin, P M O'Brien, L J Sant-Cassia

{"title":"The effect of prostaglandin E1 on the pressor response to angiotensin II in second trimester human pregnancy and in the non-pregnant subject.","authors":"F Broughton Pipkin, P M O'Brien, L J Sant-Cassia","doi":"10.3109/10641958209009621","DOIUrl":"https://doi.org/10.3109/10641958209009621","url":null,"abstract":"The effect of a simultaneous infusion of prostaglandin E1 (PGE1) on the pressor response to angiotensin II (AII) has been studied in 8 pregnant and six non-pregnant subjects to date. PGE1 15 ng kg−1 min−1 had no effect on basal blood pressures in the pregnant patients, but increased heart rate by 9.1 ± 1.6 bpm (P<0.001). Six of these eight wanen had scanewhat diminished pressor responses to AII (4, 8 and 16 ng kg−1 min−1) during PGE1 infusion; this difference reached statistical significance at the lowest dose of AII (P<0.05). PGE1 10 ng kg−1 min−1 slightly increased basal diastolic pressure in the non-pregnant subjects (P<0.05) and increased heart rate by a similar amount (8.4 ± 1.8 bpm, P<0.01). Again, the overall pressor response to AII was sanewhat diminished in the majority of these subjects. The pregnant patients exhibiting the greatest initial pressor response to AII were those in whom the greatest decrease in response was seen; this correlation achieved statistical significance at 8 and 16 ng kg−1...","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 4","pages":"493-504"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209009621","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18179581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6