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Clinical and experimental hypertension. Part B, Hypertension in pregnancy最新文献

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Uteroplacental blood flow in pre-eclampsia measurements with indium-113m and a computer-linked gamma camera. 用铟-113m和电脑连接的伽马照相机测量子痫前期子宫血流。
Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209037184
N O Lunell, L E Nylund, R Lewander, B Sarby
{"title":"Uteroplacental blood flow in pre-eclampsia measurements with indium-113m and a computer-linked gamma camera.","authors":"N O Lunell,&nbsp;L E Nylund,&nbsp;R Lewander,&nbsp;B Sarby","doi":"10.3109/10641958209037184","DOIUrl":"https://doi.org/10.3109/10641958209037184","url":null,"abstract":"<p><p>Uteroplacental blood flow was measured with a computer-linked gamma camera after intravenous injection of 1 mCi indium-113m. Results of the measurements from 32 pre-eclamptic pregnancies and 37 normal controls are compared. The uteroplacental blood flow was measured as an index calculated from the rise time and maximum activity of the isotope accumulation curve. The uteroplacental blood flow was reduced with 50% in pre-eclampsia. In severe pre-eclampsia it was more compromised than in mild pre-eclampsia. A diminished uteroplacental blood flow was found in pre-eclampsia even in the absence of intrauterine growth retardation. The maternal placental circulation in the supine position was reduced with one third compared to that in the left lateral recumbent position.</p>","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 1","pages":"105-17"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209037184","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18199350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 158
Adrenergic beta-receptor blockers in hypertension of pregnancy. 肾上腺素能受体阻滞剂在妊娠高血压中的作用。
Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01
B Sandström
{"title":"Adrenergic beta-receptor blockers in hypertension of pregnancy.","authors":"B Sandström","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This is a study of the selective beta-blocking agent metoprolol in combination with either thiazide or hydralazine in 184 hypertensive gravidae. The effects on the mother and the fetus are compared with those of 97 hypertensive gravidae treated with a combination of hydralazine and a thiazide. The combination of metoprolol and hydralazine seems to be the most favourable one judged by both maternal well-being, fetal intrauterine growth, ten-minute Apgar score and perinatal mortality. At birth the concentration of metoprolol shows a ratio of 1:1 between maternal plasma and umbilical plasma and furthermore the ratio between maternal plasma and breast milk is 1:4. The newborns of mothers on beta-blocking therapy did not differ from those of mothers on hydralazine regarding heart rate, plasma glucose or plasma bilirubin. These data indicate that fetal danger from selective beta-blocking agents during pregnancy may have been overestimated.</p>","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 1","pages":"127-41"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17201345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic regime on pregnancy induced hypertension. 妊娠高血压的治疗方案。
Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209009616
T L Liu
{"title":"Therapeutic regime on pregnancy induced hypertension.","authors":"T L Liu","doi":"10.3109/10641958209009616","DOIUrl":"https://doi.org/10.3109/10641958209009616","url":null,"abstract":"","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 4","pages":"417-28"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209009616","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17252533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colloid osmotic pressure changes during hypertensive pregnancy. 高血压妊娠期间胶体渗透压的变化。
Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209037180
R Goodlin, C Kurpershoek, H Haesslein
{"title":"Colloid osmotic pressure changes during hypertensive pregnancy.","authors":"R Goodlin,&nbsp;C Kurpershoek,&nbsp;H Haesslein","doi":"10.3109/10641958209037180","DOIUrl":"https://doi.org/10.3109/10641958209037180","url":null,"abstract":"<p><p>Colloid osmotic pressure (COP) was measured in maternal serum of normal and hypertensive gravidae, and in their amniotic fluid. Both normal and hypertensive gravidae in the third trimester at bed rest and those treated for hypertension have low COP. Likewise, postpartum women may have low serum COP values apparently unrelated to any disease process. Amniotic fluid COP is low in both normal and hypertensive gravidae. COP Measurements therefore, seemingly offers little information regarding the health of pregnant women. Serum COP may increase in some hypertensive gravidae receiving saline infusion, probably reflecting abnormal renal function and hypovolemia. High serum triglyceride values coexisting with low COP may represent hepatic efforts to produce other colloid osmotic-active substances in the semi-chronic situation, although our findings in the acute situation did not support this hypothesis.</p>","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 1","pages":"49-56"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209037180","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18200414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Simplified technique to produce toxemia in the rat: considerations on cause of toxemia. 大鼠产生毒血症的简化技术:对毒血症原因的思考。
Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209037183
M M Abitbol
{"title":"Simplified technique to produce toxemia in the rat: considerations on cause of toxemia.","authors":"M M Abitbol","doi":"10.3109/10641958209037183","DOIUrl":"https://doi.org/10.3109/10641958209037183","url":null,"abstract":"<p><p>Under ether anesthesia a silver clip was placed around the abdominal aorta of pregnant rats, thus reducing the uterine blood flow by 35-45%. This resulted in a toxemia-like syndrome comparable to the one previously produced in other animal species. Consideration is given to the hypothesis that, in a similar way, compression of the abdominal aorta by the pregnant uterus in humans produces uterine ischemia leading to toxemia.</p>","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 1","pages":"93-103"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209037183","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18200416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 43
3rd Congress of the International Society for the Study of Hypertension in Pregnancy. October 24-27, 1982, Dallas, Texas. Abstracts. 第三届妊娠期高血压研究国际学会大会。1982年10月24日至27日，德克萨斯州达拉斯。摘要。
Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209139858
{"title":"3rd Congress of the International Society for the Study of Hypertension in Pregnancy. October 24-27, 1982, Dallas, Texas. Abstracts.","authors":"","doi":"10.3109/10641958209139858","DOIUrl":"https://doi.org/10.3109/10641958209139858","url":null,"abstract":"","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 2-3","pages":"143-368"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209139858","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18155188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The rabbit: a suitable model for investigation of vascular responsiveness during pregnancy. 兔:妊娠期血管反应性研究的合适模型。
Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209009617
M I Lee, G K Oakes, R Lam, C J Hobel
{"title":"The rabbit: a suitable model for investigation of vascular responsiveness during pregnancy.","authors":"M I Lee,&nbsp;G K Oakes,&nbsp;R Lam,&nbsp;C J Hobel","doi":"10.3109/10641958209009617","DOIUrl":"https://doi.org/10.3109/10641958209009617","url":null,"abstract":"<p><p>The decreased vascular response to angiotensin II that characterizes normal pregnancy is lost in pregnancy induced hypertension and associated with an increase in response to norepinephrine. These alterations in vascular responsiveness have not been thoroughly investigated and are poorly understood. Suitable models manifesting physiologic conditions known to exist in human pregnancy have not been satisfactorily demonstrated. We investigated the chronically catheterized and unmedicated rabbit for similarities of four conditions known to occur during human pregnancy. We compared mean arterial pressure and vascular response to angiotensin II and to norepinephrine in 19 non-pregnant and 16 pregnant animals. Plasma levels of angiotensin II, norepinephrine, epinephrine, and dopamine levels were measured and compared. We found striking similarities for conditions investigated in our rabbit model when compared with data reported in the literature for human pregnancy. We conclude the rabbit is a suitable model for investigating alterations of vascular response during pregnancy.</p>","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 4","pages":"429-39"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209009617","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18179578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Clinical background of preeclampsia in Japanese women. 日本妇女先兆子痫的临床背景。
Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209009622
N Furuhashi, M Suzuki, H Kono, M Tanaka, T Takahashi, M Hiruta
{"title":"Clinical background of preeclampsia in Japanese women.","authors":"N Furuhashi,&nbsp;M Suzuki,&nbsp;H Kono,&nbsp;M Tanaka,&nbsp;T Takahashi,&nbsp;M Hiruta","doi":"10.3109/10641958209009622","DOIUrl":"https://doi.org/10.3109/10641958209009622","url":null,"abstract":"<p><p>In Japan, the maternal mortality rate from preeclampsia is still high. In this study, we analyzed the clinical background of 70(1.5%) cases of severe preeclampsia in 4,633 deliveries in our clinic. The main family history was hypertension (34.2%). The medical complication of this pregnancy were nephritis (11.4%), hypertension (5.7%) and diabetes mellitus (4.3%). In previous obstetrical complication, preeclampsia was found very high frequency (44.4%). In this pregnancy, the cesarean section was done for 15 (21.4%) cases. There was a significant high frequency of low birth weight infant in preeclampsia (2,400 +/- 925 gr, mean +/- S.D.). The stillbirth was found in 12 (17.1%) cases. The perinatal mortality rate was 169/1,000 deliveries, this was a significantly higher than total rate (15/1,000 deliveries). These data suggest that it is important to control medical complications before to be pregnant to prevent preeclampsia.</p>","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 4","pages":"505-10"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209009622","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18179582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Progesterone therapy in pregnancy induced hypertension therapeutic value and hormonal profile. 孕激素在妊娠高血压中的治疗价值及激素谱分析。
Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209009619
M B Sammour, M N El-makhzangy, M M Fawzy, A Schindler
{"title":"Progesterone therapy in pregnancy induced hypertension therapeutic value and hormonal profile.","authors":"M B Sammour,&nbsp;M N El-makhzangy,&nbsp;M M Fawzy,&nbsp;A Schindler","doi":"10.3109/10641958209009619","DOIUrl":"https://doi.org/10.3109/10641958209009619","url":null,"abstract":"<p><p>The study was carried on 25 primigravidae with severe pre-eclamptic toxaemia (PET) and 19 normal pregnancies as a control group. 15 cases of PET were treated by 600 mg. progesterone daily for variable duration between one and six weeks. Daily blood samples were assayed for progesterone, dihydroprogesterone, estriol, estradiol, placental lactogen and prolactin. Under progesterone therapy there was a significant decrease in both systolic and diastolic blood pressure, significant increase in urinary output, amelioration of the edema, slight reduction in weight gain, but no change in the proteinuria. Prolactin was the only hormone that showed significant rise in the group of PET when compared with normal pregnancy.</p>","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 4","pages":"455-78"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209009619","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18179580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
A prospective study of circulating prolactin during primigravid pregnancy. 初孕期间循环催乳素的前瞻性研究。
Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1982-01-01 DOI: 10.3109/10641958209037181
R H Hayashi, T M Siler-Khodr, R A Becker
{"title":"A prospective study of circulating prolactin during primigravid pregnancy.","authors":"R H Hayashi,&nbsp;T M Siler-Khodr,&nbsp;R A Becker","doi":"10.3109/10641958209037181","DOIUrl":"https://doi.org/10.3109/10641958209037181","url":null,"abstract":"<p><p>A prospective, cross-sectional study of 164 primigravid patients was conducted to determine the role of prolactin in the pathogenesis of pregnancy induced hypertension. Clinically normal patients had peripheral venous blood sampled from the lateral and recumbent positions monthly in the morning during their last two trimesters in labor and six weeks postpartum. One-third of the patients had 24 hour urine collections. Homologous double antibody radioimmunoassays were performed to determine prolactin levels. The data were analyzed according to pregnancy outcome: pregnancy-induced hypertension or normotensive throughout pregnancy. Acute positional change did not influence prolactin level. Prolactin levels were significantly elevated in the hypertensive outcome group only at 37-39 weeks and were not correlated with sodium excretion. We conclude that circulating prolactin does not play a significant role in pathogenesis of pregnancy-induced hypertension, but perhaps the elevated levels may be reflecting pathophysiologic changes.</p>","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"1 1","pages":"57-71"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958209037181","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18200415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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