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Clinical and experimental dialysis and apheresis最新文献

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Results of hemodialysis & hemoperfusion in the treatment of acute arsenic ingestion. 血液透析与血液灌流治疗急性砷摄入的效果。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076031
S B Smith, D G Wombolt, R Venkatesan
{"title":"Results of hemodialysis & hemoperfusion in the treatment of acute arsenic ingestion.","authors":"S B Smith,&nbsp;D G Wombolt,&nbsp;R Venkatesan","doi":"10.3109/08860228109076031","DOIUrl":"https://doi.org/10.3109/08860228109076031","url":null,"abstract":"<p><p>Hemodialysis and charcoal hemoperfusion have been used in the last few years for the treatment of acute toxin ingestion. We used these methods to treat a patient with a known ingestion of 1.3 grams of arsenic trioxide. We measured blood and urine levels of arsenic prior to and after dialytic therapy in addition to before and after conventional chelation therapy. The blood and urine levels showed no significant change with any therapy and clinically he lapsed into prolonged coma. In view of the lack of laboratory and clinical response, we feel that hemodialysis and hemoperfusion may not be indicated in acute massive ingestion. Supportive care to maintain blood pressure and urinary output may be all there is to offer. In recent years both hemodialysis and hemoperfusion have been introduced as treatment of accidental or deliberate drug or toxin ingestion. (1-4) There have been previous reports on the supposedly successful treatment of arsenic ingestion with hemodialysis. (5-6) We report our experience with a massive ingestion of arsenic trioxide. This patient received treatment with conventional chelating agents, standard hemodialysis, as well as hemoperfusion, without evidence of significant removal of arsenic or clinical benefit.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18353543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Inherited renal disease and genetic counseling. 遗传性肾脏疾病和遗传咨询。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076015
M R Kaplan
{"title":"Inherited renal disease and genetic counseling.","authors":"M R Kaplan","doi":"10.3109/08860228109076015","DOIUrl":"https://doi.org/10.3109/08860228109076015","url":null,"abstract":"<p><p>Inherited renal abnormalities and diseases are less common than acquired disorders. However, they are of great interest because their study results in increased understanding of the embryogenesis and physiology of the kidney, the pathogenesis of acquired disease, improved therapeutic approaches and accuracy of genetic counseling. Inherited defects of the kidney may be structural, functional or part of genetically transmitted systemic diseases that have major effects on renal structure and/or functions. Most structural defects of the kidney, with the exception of varying forms of cystic disease and the hereditary nephritides, are congenital and only rarely inherited in a Mendelian sense. The majority of genetically transmitted abnormalities of proximal and distal tubular function are caused by inborn metabolic errors or enzyme defects and deficiencies. Amniocentesis, ultrasonography and enzymatic assays have made the prenatal diagnosis of many inherited renal diseases possible so that more accurate counseling early therapeutic intervention may be provided.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17339912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Prevention of renal stone disease. 预防肾结石疾病。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076012
H E Williams
{"title":"Prevention of renal stone disease.","authors":"H E Williams","doi":"10.3109/08860228109076012","DOIUrl":"https://doi.org/10.3109/08860228109076012","url":null,"abstract":"The accurate prevention of renal stone disease is dependent upon a thorough understanding of the pathophysiologic mechanisms involved in the formation of renal calculi. An understanding of these mechanisms in the formation of calcium oxalate stones has allowed the development of some effective preventive therapeutic approaches.","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18084621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Stroke and gangrene: complications of therapeutic plasma exchange therapy. 脑卒中和坏疽:血浆交换治疗的并发症。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076033
N J Doll, J E Salvaggio
{"title":"Stroke and gangrene: complications of therapeutic plasma exchange therapy.","authors":"N J Doll,&nbsp;J E Salvaggio","doi":"10.3109/08860228109076033","DOIUrl":"https://doi.org/10.3109/08860228109076033","url":null,"abstract":"<p><p>Two patients underwent therapeutic plasma exchange therapy. One patient with advanced rheumatoid arthritis developed a stroke after his fifth exchange. The other patient, with progressive systemic sclerosis, required a below the knee amputation secondary to shunt problems. These cases are presented to caution physicians in selecting patients for pheresis procedures and suggest that major complications can occur with this technique.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076033","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18353544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Systemic lupus erythematosus. 系统性红斑狼疮。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076007
C L Christian
{"title":"Systemic lupus erythematosus.","authors":"C L Christian","doi":"10.3109/08860228109076007","DOIUrl":"https://doi.org/10.3109/08860228109076007","url":null,"abstract":"1.1 What is it? Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect various organs of the body, especially the skin, joints, blood, kidneys and central nervous system. \"Chronic\" means that it can last for a long time. \"Autoimmune\" means that there is a disorder of the immune system, which, instead of protecting the body from bacteria and viruses, attacks the patient’s own tissues. The name \"systemic lupus erythematosus\" dates back to the early 20th century. \"Systemic\" means that it affects many organs of the body. The word \"lupus\" is derived from the Latin word for \"wolf\" and it refers to the characteristic butterfly-like rash on the face, which is similar to the white markings on a wolf’s face. \"Erythematosus\" in Greek means \"red\" and it refers to the redness of the skin rash.","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18344672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Lymphocyte populations in maintenance hemodialysis patients - reassessment and analysis of B cell subtypes. 维持性血液透析患者的淋巴细胞群——B细胞亚型的重新评估和分析。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076025
W E Hoy, R V Cestero, R B Freeman
{"title":"Lymphocyte populations in maintenance hemodialysis patients - reassessment and analysis of B cell subtypes.","authors":"W E Hoy,&nbsp;R V Cestero,&nbsp;R B Freeman","doi":"10.3109/08860228109076025","DOIUrl":"https://doi.org/10.3109/08860228109076025","url":null,"abstract":"<p><p>Maintenance hemodialysis patients are known to be lymphopenic, and it was previously felt that T and B cells were equally and moderately depressed. With modification of the B cell technique, however, we have shown that MHD patients have a relatively more pronounced depression of B cells, with decreased proportions and markedly reduced total numbers. B cells bearing specific immunoglobulin types are all proportionally reduced. This marked B cell deficiency could be responsible for the increased rate of some infections in MHD subjects. Its relationship to azotemia, malnutrition, toxic or deficiency states, or dialysis itself is unknown, and the stages of cellular maturation or interaction which are affected have not been identified.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18345589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Depression of heart function after angiotensin II infusion in patients on chronic hemodialysis. 慢性血液透析患者血管紧张素ⅱ输注对心功能的影响。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076026
K Watanabe, Y Aizawa, A Shibata, N Obata, N Kobayashi, T Ohta
{"title":"Depression of heart function after angiotensin II infusion in patients on chronic hemodialysis.","authors":"K Watanabe,&nbsp;Y Aizawa,&nbsp;A Shibata,&nbsp;N Obata,&nbsp;N Kobayashi,&nbsp;T Ohta","doi":"10.3109/08860228109076026","DOIUrl":"https://doi.org/10.3109/08860228109076026","url":null,"abstract":"<p><p>The response of heart function to angiotensin II (AT II) was studied in 18 patients on regular hemodialysis. The mean age was 33 years and they had been dialyzed for 55 months in the average. AT II was infused from a large vein and systolic blood pressure was raised by 40 mmHg. Before and after the change in blood pressure, M-mode echocardiogram of left ventricle was recorded. Left ventricular enddiastolic dimension, stroke index and cardiac index were found to be normal except for 9 patients who showed cardiac index above 4.0L/min/m2. No significant change was found in these parameters after the rise of blood pressure by AT II. Control ejection fraction (EF) was slightly but nonsignificantly lower in the patients than the healthy subjects; 0.73 +/- 0.13 vs. 0.80 +/- 0.05. Though significant falls in EF were found in the patient and in the healthy group, the former showed a profound depression of EF to 0.64 +/- 0.10. This value was significantly lower than the value of the latter group; 0.76 +/- 0.04 (p less than 0.01). Since none had overt heart failure, a depression of EF after AT II can be regarded as subclinical abnormality of heart function. AT II will be useful to detect this limited reserve of heart function in patients on regular hemodialysis who may show normal function at rest.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18352570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quinidine pharmacokinetics in continuous ambulatory peritoneal dialysis. 奎尼丁在连续流动腹膜透析中的药代动力学。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076030
T W Chin, S Pancorbo, C Comty
{"title":"Quinidine pharmacokinetics in continuous ambulatory peritoneal dialysis.","authors":"T W Chin,&nbsp;S Pancorbo,&nbsp;C Comty","doi":"10.3109/08860228109076030","DOIUrl":"https://doi.org/10.3109/08860228109076030","url":null,"abstract":"<p><p>The clearance of quinidine was evaluated in a patient undergoing continuous ambulatory peritoneal dialysis (CAPD). The dialysis clearance of quinidine was 0.793 ml/min which represented only 0.61% of the total body clearance (154.21 ml/min) of the drug. The elimination half-life of quinidine was 5.44 hours. Based on our results, dosage adjustment of quinidine does not appear to be necessary for patients undergoing CAPD.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18352574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Environmental factors in renal disease. 肾脏疾病的环境因素。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076008
M M Reidenberg
{"title":"Environmental factors in renal disease.","authors":"M M Reidenberg","doi":"10.3109/08860228109076008","DOIUrl":"https://doi.org/10.3109/08860228109076008","url":null,"abstract":"(1981). Environmental Factors in Renal Disease. Clinical and Experimental Dialysis and Apheresis: Vol. 5, No. 1-2, pp. 101-109.","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18084619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An evaluation of the standard bubble time technique for the measurement of extracorporeal blood flow. 测量体外血流的标准泡时间技术的评价。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076016
G A Zasuwa, R Sawyer
{"title":"An evaluation of the standard bubble time technique for the measurement of extracorporeal blood flow.","authors":"G A Zasuwa,&nbsp;R Sawyer","doi":"10.3109/08860228109076016","DOIUrl":"https://doi.org/10.3109/08860228109076016","url":null,"abstract":"<p><p>Manual BT is the standard technique to use when measuring Qb for dialysis. An electro-optical system (QB-1) was devised for the measurement of BT and its relationship to real Qb. We investigated the accuracy of standard manual timing methods, the roller pump induced effects of high amplitude low frequency pulses (HALFP), the fundamental pulse of flow (Lp), and the effect of hematocrit (HCT) on BT. Blood with 15, 24, and 38 HCT was used. During dialysis, BT's were measured manually and by QB-1. With Qb greater than 200 ml/min, variations in length became insignificant. HCT did not influence BT at the values studied. In conclusion, 1) QB-1 is more accurate than manual measurements of BT, especially at higher Qb. 2) Qb greater than 200 ml/min dampens the effects of HALFP at any length of tubing. 3) HCT has no effect on BT.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18344673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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