Clinical and experimental dialysis and apheresis最新文献

The sympathetic nervous system in the pathogenesis of acute renal failure. 交感神经系统在急性肾功能衰竭发病机制中的作用。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076043

A Iaina, H E Eliahou

引用次数: 20

The role of tubuloglomerular feedback in acute impairment of renal function in obstructive jaundice. 小管肾小球反馈在梗阻性黄疸急性肾功能损害中的作用。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076040

P Wunderlich, M Hermle, J M Davis, M Mihatsch, F Brunner, G Thiel

{"title":"The role of tubuloglomerular feedback in acute impairment of renal function in obstructive jaundice.","authors":"P Wunderlich, M Hermle, J M Davis, M Mihatsch, F Brunner, G Thiel","doi":"10.3109/08860228309076040","DOIUrl":"https://doi.org/10.3109/08860228309076040","url":null,"abstract":"Acute renal functional impairment not infrequently accompanies liver dysfunction and, particularly with bile duct obstruction, may be extremely severe. Recent studies suggest that tubuloglomerular feedback (TGF) activated by circulating non-electrolyte factors which occur during liver dysfunction may contribute to the intense renal vasoconstriction thought to be central to the functional renal impairment. In this study, serum from two patients with obstructive jaundice (OJ) and renal impairment, and from rats with OJ due to bile duct ligation were either dialysed or treated with furosemide, known to block electrolyte-mediated TGF. These sera, when perfused into loops of Henle in rat nephrons, induced a significant fall of 28% in stop-flow pressure, an indirect measure of glomerular capillary pressure thus implying arteriolar vasoconstriction. These findings are consistent with the hypothesis that circulating, non-electrolyte factors, which stimulate TGF, occur in cases of obstructive jaundice and that these may contribute to the renal impairment.","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228309076040","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17933395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Adrenal responsiveness during and after intermittent haemodialysis. 间歇性血液透析期间和之后的肾上腺反应性。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076049

D Grekas, A Tourkantonis, A Pharmakiotis

{"title":"Adrenal responsiveness during and after intermittent haemodialysis.","authors":"D Grekas, A Tourkantonis, A Pharmakiotis","doi":"10.3109/08860228309076049","DOIUrl":"https://doi.org/10.3109/08860228309076049","url":null,"abstract":"ACTH and cortisol were measured by radioimmunoassay in 15 patients undergoing long term haemodialysis. Also a basal ACTH stimulation test was done by administration of 250 micrograms of Synachten (Synthetic ACTH, CIBA foundation) and the results compared with those of normal controls and end-stage chronic renal failure patients (CRF). All 15 had been receiving intermittent haemodialysis three times weekly for 5 hours on a twin coil dialyser. The duration of dialysis was from 6 to 20 months and the mean value of pre - dialysis serum creatinine was 1093 +/- 182 mumol/l. Both hormones had significantly risen in the middle and at the end of dialysis (p less than 0.005), While they had fallen back to normal mean levels 24 hours after dialysis. The Synachten stimulation test showed that adrenal response was within normal limits in both groups of patients, but dialysis patients responded significantly better (p less than 0.05) than patients with end stage CRF. We concluded that the adrenal responsiveness is within normal limits during and after regular haemodialysis and our likely explanation is a fall in plasma volume produced by the extracorporeal circulation and the increased turnover of cortisol during haemodialysis.","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228309076049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17384202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

The liaison psychiatrist and the outpatient hemodialysis unit. Part I: Reliability and validity of staff assessments of patient compliance on a hemodialysis unit. 联络精神科医生和血液透析门诊。第一部分:工作人员对血液透析单位患者依从性评估的可靠性和有效性。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076062

M Manley

引用次数: 2

Prognostic patterns in acute renal failure: the New York Hospital, 1981-1982. 急性肾衰竭的预后模式:纽约医院，1981-1982。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076045

M C Frankel, A M Weinstein, K H Stenzel

引用次数: 21

Compensatory hypertrophy of single nephrons following ischemic injury in the rat. 大鼠缺血性损伤后单个肾单位代偿性肥大。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076042

W F Finn

引用次数: 1

Renal functional and metabolic studies on the role of preventive measures in experimental acute ischemic renal failure. 预防措施在实验性急性缺血性肾功能衰竭中的作用的肾功能和代谢研究。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076041

H J Kramer, A Neumark, S Schmidt, D Klingmüller, K Glänzer

{"title":"Renal functional and metabolic studies on the role of preventive measures in experimental acute ischemic renal failure.","authors":"H J Kramer, A Neumark, S Schmidt, D Klingmüller, K Glänzer","doi":"10.3109/08860228309076041","DOIUrl":"https://doi.org/10.3109/08860228309076041","url":null,"abstract":"In the present study 1 h of total occlusion of the left renal artery in conscious rats was chosen as experimental model of ischemic acute renal failure (ARF), while the contralateral kidney was left intact. Chronic high dietary sodium intake, acute isotonic saline infusion, or administration of saralasin did not protect from ARF. Furosemide, mannitol, and verapamil converted oliguric into non-oliguric ARF in 100%, 75%, and 60% of the animals, resp. Protection from oliguria and preservation of GFR inversely correlated with the depression of cortical ATP-concentration (control: 1.32 +/- 0.07 mumoles/g wet weight) 6 h after ischemia by 16%, 41%, and 58% in mannitol- and verapamil- treated rats and in untreated rats, resp. At this time, Na-K-ATPase enzyme activities in renal cortex and papilla were unaffected, while enzyme activity in outer medulla was suppressed from 15.4 +/- 1.4 to 9.4 +/- 1.0 mumoles Pi/mg protein h in all groups of animals. The results suggest that in this model of ARF renal ischemia not only affects cellular energy supply in renal cortex but also causes severe structural and functional impairment in the outer medulla, probably leading to tubular obstruction and depression of glomerular function. Pharmacological protection from ischemic oliguric ARF cannot be achieved by prior induction of high urine flow rates alone but depends on the degree of metabolic and functional reserve of the injured tubular epithelium.","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228309076041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17470381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

When transplantation is not the answer. 移植并不能解决问题。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076060

P G Wilson

引用次数: 1

A pharmacokinetic evaluation of the effect of plasma exchange on tobramycin disposition. 血浆置换对妥布霉素处置影响的药代动力学评价。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076052

S M Ouellette, J A Visconti, M S Kennedy

引用次数: 12

A CAPD patient group on sexuality--a critical view. CAPD的性取向病人小组，一个批判的观点。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076058

U Davenport, L Strawgate-Kanefsky

引用次数: 2