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Clinical and experimental dialysis and apheresis最新文献

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The role of lead in renal failure. 铅在肾衰竭中的作用。
Clinical and experimental dialysis and apheresis Pub Date : 1982-01-01 DOI: 10.3109/08860228209050819
R P Wedeen
{"title":"The role of lead in renal failure.","authors":"R P Wedeen","doi":"10.3109/08860228209050819","DOIUrl":"https://doi.org/10.3109/08860228209050819","url":null,"abstract":"<p><p>The CaNa2EDTA lead mobilization test permits identification of lead nephropathy in a variety of situations in which past-exposure is uncertain and acute symptoms of lead poisoning are lacking. In addition to lead workers and moonshiners, lead nephropathy has been identified in gout patients with renal failure and in hypertensives with renal failure. The presence of excessive mobilizable lead in these patients and its absence in control patients with comparable renal dysfunction suggests that unrecognized lead poisoning is sometimes responsible for renal failure in gout and hypertension. Use of the EDTA lead-mobilization test may thus permit prevention and sometimes treatment of renal failure in patients who might otherwise enter the End-Stage Renal-Disease Program. The controversies surrounding interstitial nephritis in lead poisoning, gout and hypertension may in part be explained by the surreptitious role of lead.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228209050819","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17811523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Gardnerella vaginalis (hemophilus vaginalis), an unusual cause of peritonitis in C.A.P.D. 阴道加德纳菌(阴道血友病)，腹膜炎的一个不寻常的原因，在c.a.p.d
Clinical and experimental dialysis and apheresis Pub Date : 1982-01-01 DOI: 10.3109/08860228209049852
M De Paepe, N Lameire, G Claeys, G Verschraegen
{"title":"Gardnerella vaginalis (hemophilus vaginalis), an unusual cause of peritonitis in C.A.P.D.","authors":"M De Paepe,&nbsp;N Lameire,&nbsp;G Claeys,&nbsp;G Verschraegen","doi":"10.3109/08860228209049852","DOIUrl":"https://doi.org/10.3109/08860228209049852","url":null,"abstract":"<p><p>Gardnerella vaginalis is usually associated with nonspecific bacterial vaginitis. This paper presents a CAPD patiënt with peritonitis due to G. vaginalis. The infection route remained speculative. Treatment with gentamicin was not successful while the clinical signs of peritonitis disappeared within 24 hours after starting cefazolin.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228209049852","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18034374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Acute hemodynamic effects of Brescia-Cimino arteriovenous fistula for hemodialysis. 布雷西亚-西米诺动静脉瘘对血液透析的急性血流动力学影响。
Clinical and experimental dialysis and apheresis Pub Date : 1982-01-01 DOI: 10.3109/08860228209050809
A Balbarini, G Tartarini, M Tuoni, R Palla, A Barsotti, M Mariani
{"title":"Acute hemodynamic effects of Brescia-Cimino arteriovenous fistula for hemodialysis.","authors":"A Balbarini,&nbsp;G Tartarini,&nbsp;M Tuoni,&nbsp;R Palla,&nbsp;A Barsotti,&nbsp;M Mariani","doi":"10.3109/08860228209050809","DOIUrl":"https://doi.org/10.3109/08860228209050809","url":null,"abstract":"<p><p>In ten uremic patients, who were not yet undergoing periodic hemodialysis and in whom we were creating a 1 cm, distal, side-to-side arteriovenous fistula of Brescia-Cimino type for hemodialysis, the acute hemodynamic changes of the systemic and pulmonary circulations were studied immediately after the opening of the fistula. An increase in cardiac output (Q) was observed in one patient, the other patients showing either no change or a slight reduction. In the four patients in whom the Q decreased there was a significant reduction of total blood volume (TBV) and stroke volume (SV) and an increase in systemic vascular resistance (SVR) (p less than 0.05, p less than 0.05, p less than 0.01 respectively). At the level of pulmonary circulation, in these patients a decrease in pulmonary blood volume (PBV) (mean = 20%) and a significant increase in pulmonary vascular resistance (PVR) were also observed. In five patients who had been on chronic hemodialysis and who presented the clinical picture of cardiac failure, the acute hemodynamic changes following temporary closure of the fistula (by a sphygmomanometer) were studied: a significant decrease (p less than 0.05) in Q, TBV and SV was observed. The difference between the two values of Q (i.e. fistula open and closed) was considered to indicate the magnitude of the flow across the fistula.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228209050809","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35220363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of stagnant fluid films during simulated peritoneal dialysis: in-vitro and in-vivo studies. 模拟腹膜透析期间滞流膜的评估:体外和体内研究。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076021
J Rubin, K Kirchner, J Bower
{"title":"Evaluation of stagnant fluid films during simulated peritoneal dialysis: in-vitro and in-vivo studies.","authors":"J Rubin,&nbsp;K Kirchner,&nbsp;J Bower","doi":"10.3109/08860228109076021","DOIUrl":"https://doi.org/10.3109/08860228109076021","url":null,"abstract":"<p><p>Peritoneal dialysis as conventionally performed is an intermittent low dialysate flow system. Few studies have explored the effects of the intermittent nature of dialysate flow. Using an in-vitro model, we demonstrated that conventional peritoneal dialysis permits the development of stagnant fluid films and that by disruption of these films, dialysance could be augmented. We tested and confirmed these observations by carrying out peritoneal dialysis in rats. Stagnant fluid films may be an important contributor to overall membrane resistance in the peritoneal dialysis system</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076021","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18345586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Experience with subclavian vein for vascular access. 锁骨下静脉血管通路经验。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076022
S B Smith, D G Wombolt, R L Hurwitz, J R Wheeler, M Goldberg
{"title":"Experience with subclavian vein for vascular access.","authors":"S B Smith,&nbsp;D G Wombolt,&nbsp;R L Hurwitz,&nbsp;J R Wheeler,&nbsp;M Goldberg","doi":"10.3109/08860228109076022","DOIUrl":"https://doi.org/10.3109/08860228109076022","url":null,"abstract":"<p><p>We report our experience with the subclavian vein as a route for temporary vascular access. By modifying the technique described by Uldall one can place these catheters at the bedside without the need of a separate exit tunnel. They are easily maintained in place and allow for early discharge home while awaiting permanent vascular access maturation. The results of approximately 600 dialysis treatments showed adequate clearence with a mean postdialysis drop in creatinine of 5.0mg./dl. and BUN of 46mg./dl. Complication rates were minimal with no hemo or pneumothorax. The rate of complications between bedside and operating room placement was not different. We feel the low complication rate, the ease of insertion, and the patency at home makes this an attractive alternative to other means of temporary dialysis such as: peritoneal dialysis, repeat femoral vein catheterization or arteriovenous shunts.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18345587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Gel layer limited haemofiltration rates can be increased by vortex mixing. 凝胶层限制的血液过滤率可以通过涡流混合来提高。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076028
M A Jeffree, J Peacock, I J Sobey, B J Bellhouse
{"title":"Gel layer limited haemofiltration rates can be increased by vortex mixing.","authors":"M A Jeffree,&nbsp;J Peacock,&nbsp;I J Sobey,&nbsp;B J Bellhouse","doi":"10.3109/08860228109076028","DOIUrl":"https://doi.org/10.3109/08860228109076028","url":null,"abstract":"<p><p>Haemofiltration has been used since 1976 as an alternative to haemodialysis in the treatment of chronic renal failure (1). Ultrafiltration flow rates (UFR) from blood are slow and it has been observed that when blood or plasma is ultrafiltered using highly permeable membranes, the UFR reaches a maximum which is independent of trans-membrane pressure (delta Pm) (2). We have confirmed this result during steady flow through an ultrafilter employing polyacrylonitrile membrane (Rhône Poulenc AN 69) but have also shown that this maximum can be exceeded by a factor of eight in the same device when vortex mixing is induced by pulsing the blood flow over furrowed channels.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076028","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18352572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
Diabetic glomerulopathy may be preventable. 糖尿病肾小球是可以预防的。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076006
A Friedman, C Levitz, M Hirsch, K M Butt
{"title":"Diabetic glomerulopathy may be preventable.","authors":"A Friedman,&nbsp;C Levitz,&nbsp;M Hirsch,&nbsp;K M Butt","doi":"10.3109/08860228109076006","DOIUrl":"https://doi.org/10.3109/08860228109076006","url":null,"abstract":"<p><p>Variation in blood glucose levels throughout the day was assessed in six diabetic maintenance hemodialysis patients and six diabetic renal transplant recipients. None of the twelve studied patients had good control. Glucose levels greater than 300 mg/dl were noted in four of six dialysis patients and five of six transplant recipients. A regimen of self blood glucose measurement and multiple insulin doses was instituted for four transplant and three dialysis patients. Each patient achieved the desired glucose range of 60 to 120 mg/dl most of the time, with a resultant fall in mean hemoglobin A1c concentration from 10.3% to 7.9%. It is suggested that a long term trial of self glucose monitoring might prove beneficial to treated uremic diabetics.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18084481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Vasculitic diseases. Vasculitic疾病。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076004
J E Balow
{"title":"Vasculitic diseases.","authors":"J E Balow","doi":"10.3109/08860228109076004","DOIUrl":"https://doi.org/10.3109/08860228109076004","url":null,"abstract":"","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17187581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Immunosuppressive treatment in the prevention of renal failure in primary glomerular diseases. 免疫抑制治疗在预防原发性肾小球疾病肾衰竭中的作用。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076003
R J Glassock
{"title":"Immunosuppressive treatment in the prevention of renal failure in primary glomerular diseases.","authors":"R J Glassock","doi":"10.3109/08860228109076003","DOIUrl":"https://doi.org/10.3109/08860228109076003","url":null,"abstract":"<p><p>Despite the relative paucity of well controlled studies, there is reason for cautious optimism with respect to favorably influencing the course of certain primary glomerular diseases with pharmacologic therapy. Particularly promising in this regard is the role of corticosteroids in membranous nephropathy, anticoagulant and antithrombotic agents in membranoproliferative glomerulonephritis and high-dose \"pulse\" steroids, \"quadruple therapy\" or plasma exchange with immunosuppression in idiopathic crescentic glomerulonephritis. Further controlled trials are urgently needed in the various forms of mesangial proliferative glomerulonephritis, including Berger's disease, in focal and segmental glomerulosclerosis and membranous nephropathy in which reduced GFR or steroid resistance has been demonstrated. It seems quite clear that even a temporary delay in the onset of ESRD, if such can be obtained with a minimum of lasting side effects, is a reasonable goal of therapy considering the expense of maintenance dialysis and transplantation.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18084479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Mechanisms of progression in glomerulonephritis. 肾小球肾炎的进展机制。
Clinical and experimental dialysis and apheresis Pub Date : 1981-01-01 DOI: 10.3109/08860228109076002
D S Baldwin
{"title":"Mechanisms of progression in glomerulonephritis.","authors":"D S Baldwin","doi":"10.3109/08860228109076002","DOIUrl":"https://doi.org/10.3109/08860228109076002","url":null,"abstract":"<p><p>Although most forms of glomerulonephritis in man are thought to have an immunopathogenesis, certain clinical and experimental observations support the role of other non-immunologic mechanisms in the progression of these diseases. 1. Intra-renal vascular disease thought to be secondary to hypertension, may be responsible for ischemic glomerular sclerosis. 2. Hypertension may damage the diseased glomerulus directly, as has been demonstrated in experimental glomerulonephritis, in the remnant kidney, and in experimental diabetes mellitus. 3. Alterations in glomerular structure and function in the remnant kidney suggest that adaptations to nephron loss may contribute to further renal damage. 4. Glomerular sclerosis occurs under circumstances where immunologic mechanisms are highly unlikely, such as aging, reflex nephropathy, chronic aminonucleoside administration, and protein loading. 5. Preservation of renal function can be achieved by phosphorus restriction in the remnant kidney and in nephrotoxic serum nephritis.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228109076002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18084618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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