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Renal Lobulation—A Benign Macroanatomical Variation? 肾分叶——一种良性宏观解剖学变异?
Anatomia Pub Date : 2023-11-08 DOI: 10.3390/anatomia2040030
Serghei Covantsev, Oleg Arnaut, Karina Mulaeva, Olga Belic
{"title":"Renal Lobulation—A Benign Macroanatomical Variation?","authors":"Serghei Covantsev, Oleg Arnaut, Karina Mulaeva, Olga Belic","doi":"10.3390/anatomia2040030","DOIUrl":"https://doi.org/10.3390/anatomia2040030","url":null,"abstract":"Introduction: Renal lobulation (also known as fetal or embryonic lobulation) is a rare variation during development in which renal lobules have a visible anatomical space between them, and this can be seen in 0.5–4% of adults. Material and methods: this study was conducted on 54 human kidneys from patients who died due to causes unrelated to renal pathology which were fixed in a 10% formaldehyde solution and then carefully dissected. Results: The group with fetal lobulation (n = 16) was associated with a length M = 9.89 (SD = 0.6, p = 0.15). By comparison, the kidneys without lobulation (n = 38) were associated with a numerically longer length M = 10.29 (SD = 0.607, p = 0.098). To test the hypothesis that lobulation is associated with a statistically significant different length a Mann–Whitney test was performed, which indicated that the length of the kidneys is smaller in scase of lobulation U = 198, Z = −2.04, p = 0.04. Cross-tabulation also demonstrated that kidney lobulation may be influenced by the presence of polar arteries with r = 0.41 (p < 0.02). The likelihood ratio was 7.28, df 1, p = 0.003, with an odds ratio of 6.857 (CI 95% = 1.84–25.61). Logistic regression analysis demonstrated that kidneys with lobulation were 6.85 times more likely to have polar arteries than kidneys without lobulation. Conclusions: the data from our research indicate that even though no pathological conditions have been linked with lobulated kidneys, the incidence of vascular variations (specifically polar arteries) is higher when there is persistent fetal lobulation.","PeriodicalId":7888,"journal":{"name":"Anatomia","volume":"49 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135430508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hippocampal Asymmetry Increases with Age 海马体不对称性随年龄增长而增加
Anatomia Pub Date : 2023-10-16 DOI: 10.3390/anatomia2040029
Florian Kurth, Eileen Luders
{"title":"Hippocampal Asymmetry Increases with Age","authors":"Florian Kurth, Eileen Luders","doi":"10.3390/anatomia2040029","DOIUrl":"https://doi.org/10.3390/anatomia2040029","url":null,"abstract":"It is unclear whether differences between the two brain hemispheres become larger or smaller with increasing age. Given that the hippocampus is particularly susceptible to age-related changes, here, we set out to investigate the correlation between chronological age and hippocampal asymmetry, both for the hippocampal complex as a whole and in cytoarchitectonically defined subregions (cornu ammonis 1, 2, 3, dentate gyrus, subiculum, and entorhinal cortex). We analyzed T1-weighted data of the brain from a sample of 725 healthy individuals (406 women/319 men) spanning a wide age range (36–100 years) from The Lifespan Human Connectome Project in Aging. Correlations between the absolute asymmetry index and chronological age were positive for all six subregions and also for the hippocampal complex as a whole, albeit effects the effects were not significant for the dentate gyrus. This suggests that, overall, hippocampal asymmetry increases with increasing age (i.e., the left and right hippocampi become more different over time). Given that the subregions of the hippocampal complex serve different brain functions, follow-up research is needed to explore the functional implications within the framework of brain aging. In addition, longitudinal studies will be necessary to confirm the observed cross-sectional effects.","PeriodicalId":7888,"journal":{"name":"Anatomia","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136112820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Bilateral Variation in the Branches of the Internal Thoracic Artery: A Case Report 胸内动脉分支罕见双侧变异1例
Anatomia Pub Date : 2023-10-12 DOI: 10.3390/anatomia2040028
Jihad S. Hawi, Rosalyn A. Jurjus, Hisham S. Daouk, Maya N. Ghazi, Charbel A. Basset, Francesco Cappello, Inaya Hajj Hussein, Angelo Leone, Abdo R. Jurjus
{"title":"A Rare Bilateral Variation in the Branches of the Internal Thoracic Artery: A Case Report","authors":"Jihad S. Hawi, Rosalyn A. Jurjus, Hisham S. Daouk, Maya N. Ghazi, Charbel A. Basset, Francesco Cappello, Inaya Hajj Hussein, Angelo Leone, Abdo R. Jurjus","doi":"10.3390/anatomia2040028","DOIUrl":"https://doi.org/10.3390/anatomia2040028","url":null,"abstract":"Background: Anatomical variations and, in particular, arterial variations constitute an important chapter in the learning of Clinical Anatomy. Purpose: The purpose of this report is to describe a rare bilateral anatomical variation in the internal thoracic artery (ITA) in a 60-year-old corpse and to depict its extreme clinical importance in coronary artery bypass surgery. Methods: The rare bilateral aberrant branches of the internal thoracic artery and their course in the thorax were incidentally discovered during routine anatomy dissection of the thorax at the Faculty of Medicine and Medical Sciences of the University of Balamand. The findings were thoroughly documented using digital photography, and the dissection followed the instructions from the “16th Edition of Grant’s Dissector”. Results: In the observed case, the left aberrant branch of ITA descends laterally and gives medial and lateral anterior intercostal branches at the first six intercostal spaces. Conversely, the right aberrant artery, which branches from the ITA, descends laterally and gives medial and lateral branches to every intercostal space in the first five intercostal spaces. Conclusion: This report emphasizes that any unexpected variations in the lateral aberrant branches of the internal thoracic artery may complicate the surgical procedure. Bilateral aberrant lateral branches of the internal thoracic artery constitute rare anatomical variations of the internal thoracic artery and have been rarely reported in the literature. Such a course for aberrant lateral branches in the thorax poses possible lethal complications during several procedures involving the thorax, including basic coronary artery bypass graft, thoracocentesis and intercostal paracentesis and breast reconstruction.","PeriodicalId":7888,"journal":{"name":"Anatomia","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136013961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Anatomy of Prostate Cancer and Its Implications in Active Surveillance and Early Intervention Strategies 前列腺癌的分子解剖及其在主动监测和早期干预策略中的意义
Anatomia Pub Date : 2023-10-10 DOI: 10.3390/anatomia2040027
Sandy Figiel, Géraldine Cancel-Tassin, Ian G. Mills, Alastair D. Lamb, Gaelle Fromont, Olivier Cussenot
{"title":"Molecular Anatomy of Prostate Cancer and Its Implications in Active Surveillance and Early Intervention Strategies","authors":"Sandy Figiel, Géraldine Cancel-Tassin, Ian G. Mills, Alastair D. Lamb, Gaelle Fromont, Olivier Cussenot","doi":"10.3390/anatomia2040027","DOIUrl":"https://doi.org/10.3390/anatomia2040027","url":null,"abstract":"Understanding prostate carcinogenesis is crucial not only for identifying new treatment targets but also for developing effective strategies to manage the asymptomatic form of the disease. There is a lack of consensus about predicting the indolent form of the disease prostate cancer, leading to uncertainties regarding treatment initiation. This review aims to enhance the assessment and management of early prostate cancer by providing a comprehensive picture of the molecular anatomy of the prostate, synthesising current evidence, highlighting knowledge gaps, and identifying future directions. It presents evidence for the efficacy of active surveillance as an alternative treatment strategy and its potential benefits in specific patient groups through androgen receptor disruption. Overall, an improved understanding of prostate carcinogenesis and its molecular underpinnings can pave the way for tailored and precise management approaches for this common cancer. Further development and validation of molecule-based assessment tools are needed. Integrating genomic, proteomic, and phenotypic models, as well as functional approaches, can help predict outcomes. This facilitates selecting candidates for active surveillance and targeting interventions for higher-risk cases, contributing to more precise management strategies.","PeriodicalId":7888,"journal":{"name":"Anatomia","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136356705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiological Diagnosis and Imaging of Femoral Shaft Fractures 股骨干骨折的影像学诊断
Anatomia Pub Date : 2023-09-07 DOI: 10.3390/anatomia2030026
Kathleen H Miao, Julia H. Miao
{"title":"Radiological Diagnosis and Imaging of Femoral Shaft Fractures","authors":"Kathleen H Miao, Julia H. Miao","doi":"10.3390/anatomia2030026","DOIUrl":"https://doi.org/10.3390/anatomia2030026","url":null,"abstract":"Femoral shaft fractures (FSFs) are common orthopedic injuries, often resulting from high-energy trauma such as motor vehicle collisions, low-energy trauma, osteoporosis, or pathological conditions. They account for a significant portion of long bone fractures. Radiologic imaging plays a pivotal role in the diagnosis of these fractures, providing crucial information about fracture characteristics, associated injuries, and successful treatment and management planning. This paper provides a comprehensive review of the anatomy, pathophysiology, and classification systems of FSFs. Diagnostic imaging modalities, including radiograph, computed tomography (CT), and magnetic resonance imaging (MRI), and their essential roles are highlighted, driving treatment and management as well as prognosis for FSFs and illuminating the anatomical considerations that influence the choice of approach and fixation techniques. Radiological diagnosis and imaging of FSFs are vital for orthopedic surgeons, radiologists, and healthcare professionals involved in the care of patients with these injuries and optimizing patient outcomes.","PeriodicalId":7888,"journal":{"name":"Anatomia","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80956021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metacognition through an Iterative Anatomy AI Chatbot: An Innovative Playing Field for Educating the Future Generation of Medical Students 通过迭代解剖人工智能聊天机器人的元认知:教育下一代医学生的创新竞争环境
Anatomia Pub Date : 2023-09-06 DOI: 10.3390/anatomia2030025
Varna Taranikanti, Cameron J. Davidson
{"title":"Metacognition through an Iterative Anatomy AI Chatbot: An Innovative Playing Field for Educating the Future Generation of Medical Students","authors":"Varna Taranikanti, Cameron J. Davidson","doi":"10.3390/anatomia2030025","DOIUrl":"https://doi.org/10.3390/anatomia2030025","url":null,"abstract":"Medical educators face many challenges instructing future medical students, specifically in the integration of learning technologies. To overcome these challenges, educators must implement learner-centered and interactive teaching strategies. Anatomical sciences are the cornerstone of medical education and provide the bedrock to layer conceptual understanding of the human body. With the “medical knowledge boom”, most medical schools have reduced the curricular time for anatomy instruction, resulting in a paucity of knowledge and issues incorporating anatomical knowledge in clinical scenarios. Modern pedagogical techniques combining AI chatbots with concurrent metacognitive frameworks can foster a deeper understanding of anatomical knowledge and analysis of clinical cases. Student reflection on the learning process allows for monitoring their progress and tailoring of learning strategies to their specific capabilities and needs. A.I. technology can aid in scaffolding knowledge with practical applications via iterative and immediate feedback in case- or problem-based learning formats. The use of textual conversations actively engages students and simulates conversations with instructors. In this communication, we advocate for the incorporation of AI technologies fused with a metacognitive framework as a medium to foster increased critical thinking and skill development that enhances comprehension. These skills are important for medical students’ lifelong learning process.","PeriodicalId":7888,"journal":{"name":"Anatomia","volume":"17 12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78497080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Anatomist and Co-Founder of Polish Veterinary Education—Ludwik Henryk Bojanus (1776–1827) 解剖学家和波兰兽医教育的联合创始人-路德维克·亨利克·波加努斯(1776-1827)
Anatomia Pub Date : 2023-09-04 DOI: 10.3390/anatomia2030024
Jarosław Sobolewski, M. Zdun
{"title":"Anatomist and Co-Founder of Polish Veterinary Education—Ludwik Henryk Bojanus (1776–1827)","authors":"Jarosław Sobolewski, M. Zdun","doi":"10.3390/anatomia2030024","DOIUrl":"https://doi.org/10.3390/anatomia2030024","url":null,"abstract":"Ludwig Henry Bojanus was born on 16 July 1776 in Buchsweiler, Alsace. After studying in Jena and Vienna, L. H. Bojanus enrolled at the University of Jena for his doctoral studies. Bojanus’s scientific activities are closely associated with Vilnius, where he was a professor of veterinary medicine from 1806 (he was elected to this position in 1804). In 1815, he became a professor of comparative anatomy. These were the times of the greatest flourishing of Vilnius University, where the foundations of modern Polish science were being laid. At Vilnius University, he established a technical and anatomical-pathological office for the zoo, a veterinary clinic and a model forge for shoeing horses in 1823. Bojanus founded a veterinary school in Vilnius and drew up a plan for a veterinary institute, which was not opened until 1832, simultaneously with the opening of the medico-surgical academy. He became known as one of Europe’s most prominent anatomists and zoologists. A lasting memorial to the scientist is the monograph “Anatomy of the Tortoise”, which many scholars still point to today as a model of accurate and precise anatomical research. He was the first to identify the anatomical differences between the European bison (Bos bonasus) and the aurochs (Bos primigenius). In his lectures on comparative anatomy, Bojanus presented the principle of uninterrupted development. He can be described as one of the most decisive and consistent evolutionists before Darwin. He died in 1827.","PeriodicalId":7888,"journal":{"name":"Anatomia","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73648021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Prostate Is Not a Pill and Therefore Has No Capsule 前列腺不是药丸,所以没有胶囊
Anatomia Pub Date : 2023-08-14 DOI: 10.3390/anatomia2030023
J. Kläger, Gabriel Wasinger, A. Oszwald, E. Compérat
{"title":"The Prostate Is Not a Pill and Therefore Has No Capsule","authors":"J. Kläger, Gabriel Wasinger, A. Oszwald, E. Compérat","doi":"10.3390/anatomia2030023","DOIUrl":"https://doi.org/10.3390/anatomia2030023","url":null,"abstract":"Tumor staging of prostate cancer is a fundamental principle in management and therapy, with a hallmark being tumor growth beyond the organ boundary. Often, this is referred to as “capsule penetration”, suggesting the existence of a true prostatic capsule that would facilitate the determination of tumor penetration. In fact, the prostate does not have a true capsule and, depending on the anatomic area, it blends with the surrounding fibrous, adipose and muscular tissue. This makes it sometimes difficult or impossible to unequivocally identify extraprostatic tumor extension. It is necessary to appreciate this difficulty in order to better understand the significance of extraprostatic tumor extension.","PeriodicalId":7888,"journal":{"name":"Anatomia","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85611139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brain Abscess Secondary to an Apparently Benign Transorbital Injury: An Infrequent Case Report with Literature Review 脑脓肿继发于明显良性的眼眶损伤:一例罕见病例报告并文献复习
Anatomia Pub Date : 2023-08-09 DOI: 10.3390/anatomia2030022
H. Bečulić, Emir Begagić, Rasim Skomorac, Aldin Jusic, E. Selimović, Lejla Čejvan, Mirza Pojskić
{"title":"Brain Abscess Secondary to an Apparently Benign Transorbital Injury: An Infrequent Case Report with Literature Review","authors":"H. Bečulić, Emir Begagić, Rasim Skomorac, Aldin Jusic, E. Selimović, Lejla Čejvan, Mirza Pojskić","doi":"10.3390/anatomia2030022","DOIUrl":"https://doi.org/10.3390/anatomia2030022","url":null,"abstract":"Intraorbital and transorbital injuries are included in the group of head injuries with low frequency. In particular, such injuries rarely result in infectious processes in the brain parenchyma. This case presents a case where a 57-year-old man reported to the neurosurgery department that he had sustained an injury to the conjunctiva of the upper eyelid a month earlier. The patient was injured by a tree branch, which he removed on his own initiative. After persistent eye abduction palsy, an MRI was performed, which showed a compressive mass in the frontal lobe of the brain. A surgical procedure was indicated, which found a piece of twig 3 mm long inside the abscess. Surgical intervention and antibiotic therapy led to the complete recovery of the patient.","PeriodicalId":7888,"journal":{"name":"Anatomia","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87947202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Geometric Anatomy Basis for Safe and Effective Focal Ablation of Prostate Cancer by Irreversible Electroporation (IRE) 不可逆电穿孔(IRE)安全有效的前列腺癌病灶消融的几何解剖学基础
Anatomia Pub Date : 2023-08-04 DOI: 10.3390/anatomia2030021
O. Cussenot, R. Macpherson, T. Leslie, L. Lunelli, G. Marra, M. Laniado, F. Hamdy, R. Bryant
{"title":"Geometric Anatomy Basis for Safe and Effective Focal Ablation of Prostate Cancer by Irreversible Electroporation (IRE)","authors":"O. Cussenot, R. Macpherson, T. Leslie, L. Lunelli, G. Marra, M. Laniado, F. Hamdy, R. Bryant","doi":"10.3390/anatomia2030021","DOIUrl":"https://doi.org/10.3390/anatomia2030021","url":null,"abstract":"Irreversible electroporation (IRE) is a recent and minimally invasive method of partial prostate ablation. However, knowledge of the essential landmarks of prostate anatomy is crucial to achieving safe and effective partial ablation by IRE. High-quality imaging of the prostate is essential before the procedure. The individual morphological pattern of the prostate must be taken into account and detailed mapping with measurement of the lesion is necessary to determine optimal needle placement. The entire tumour volume must be covered while ensuring the safety of critical anatomical structures such as the rectum, urethra, nerve bundles and sphincter muscle.","PeriodicalId":7888,"journal":{"name":"Anatomia","volume":"118 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75769275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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