Serghei Covantsev, Oleg Arnaut, Karina Mulaeva, Olga Belic
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引用次数: 0
摘要
肾小叶化(也称为胎儿或胚胎小叶化)是一种罕见的发育变异,其肾脏小叶之间有明显的解剖间隙,在0.5-4%的成年人中可见。材料和方法:本研究取材于与肾脏病理无关的死亡患者的54个肾脏,将其固定在10%的甲醛溶液中,然后仔细解剖。结果:胎儿分叶组(n = 16)与长度M = 9.89相关(SD = 0.6, p = 0.15)。相比之下,没有分叶的肾脏(n = 38)的数值长度较长,M = 10.29 (SD = 0.607, p = 0.098)。为了检验分叶化与不同长度有统计学意义相关的假设,我们进行了Mann-Whitney检验,结果表明分叶化的肾脏长度较小U = 198, Z =−2.04,p = 0.04。交叉表法还显示,肾分叶化可能受到极动脉存在的影响,r = 0.41 (p <0.02)。似然比为7.28,df 1, p = 0.003,优势比为6.857 (CI 95% = 1.84 ~ 25.61)。Logistic回归分析显示,有分叶的肾脏出现极动脉的可能性是没有分叶的肾脏的6.85倍。结论:我们的研究数据表明,尽管没有病理条件与分叶肾有关,但当胎儿持续分叶时,血管变异(特别是极动脉)的发生率更高。
Introduction: Renal lobulation (also known as fetal or embryonic lobulation) is a rare variation during development in which renal lobules have a visible anatomical space between them, and this can be seen in 0.5–4% of adults. Material and methods: this study was conducted on 54 human kidneys from patients who died due to causes unrelated to renal pathology which were fixed in a 10% formaldehyde solution and then carefully dissected. Results: The group with fetal lobulation (n = 16) was associated with a length M = 9.89 (SD = 0.6, p = 0.15). By comparison, the kidneys without lobulation (n = 38) were associated with a numerically longer length M = 10.29 (SD = 0.607, p = 0.098). To test the hypothesis that lobulation is associated with a statistically significant different length a Mann–Whitney test was performed, which indicated that the length of the kidneys is smaller in scase of lobulation U = 198, Z = −2.04, p = 0.04. Cross-tabulation also demonstrated that kidney lobulation may be influenced by the presence of polar arteries with r = 0.41 (p < 0.02). The likelihood ratio was 7.28, df 1, p = 0.003, with an odds ratio of 6.857 (CI 95% = 1.84–25.61). Logistic regression analysis demonstrated that kidneys with lobulation were 6.85 times more likely to have polar arteries than kidneys without lobulation. Conclusions: the data from our research indicate that even though no pathological conditions have been linked with lobulated kidneys, the incidence of vascular variations (specifically polar arteries) is higher when there is persistent fetal lobulation.