Anatolian Journal of Cardiology最新文献

{"title":"A Composite Electrophysiological Descriptor of Atrioventricular Nodal Conduction and Non-inducible Atrioventricular Nodal Reentrant Tachycardia: Findings from a Retrospective Electrophysiological Cohort.","authors":"Aykan Çelik, Uğur Kocabaş, Elif Naz Uçak, Ali Efe Afşin, Tuncay Kırış, Mustafa Karaca","doi":"10.14744/AnatolJCardiol.2026.6595","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2026.6595","url":null,"abstract":"<p><strong>Objective: </strong>To examine whether a simple electrophysiological descriptor derived from routinely measured antegrade atrioventricular nodal conduction parameters is associated with non-inducible atrioventricular nodal reentrant tachycardia (AVNRT).</p><p><strong>Methods: </strong>This retrospective cohort included 387 consecutive patients undergoing electrophysiological study for clinically suspected AVNRT. The Total Antegrade Nodal Delay (TAND) index was defined as the sum of the atrio-His (AH) interval and antegrade Wenckebach cycle length (WBCL). Logistic regression, receiver operating characteristic analysis, and quadrant-based continuum analysis were performed. Because WBCL values were missing predominantly in inducible patients, complete-case and sensitivity analyses were conducted.</p><p><strong>Results: </strong>Non-inducible AVNRT occurred in 106 patients (27.4%). In the complete-case TAND cohort (n = 329), higher TAND values were associated with non-inducibility (odds ratio [OR] per 50-ms increase: 1.26, 95% CI: 1.02-1.56, P = .032), remaining significant after adjustment for age and sex (adjusted OR: 1.31, 95% CI: 1.05-1.63, P = .016). Discrimination was modest (area under the curve: 0.592, 95% CI: 0.525-0.659). After multiple imputation, the association remained directionally consistent but was attenuated (adjusted OR: 1.21, 95% CI: 0.99-1.46, P = .056). Quadrant analysis demonstrated a graded increase in non-inducibility from the low-AH/low-WBCL to the high-AH/high-WBCL quadrant (25.0% vs. 42.3%; trend OR: 1.32, 95% CI: 1.07-1.61, P = .008).</p><p><strong>Conclusion: </strong>Total Antegrade Nodal Delay was modestly associated with non-inducible AVNRT and may describe a group-level electrophysiological pattern characterized by slower antegrade nodal conduction and higher functional conduction thresholds. However, TAND should not be interpreted as a mechanistic requirement for AVNRT inducibility or as an individual-level prediction tool.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148824034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The BREATH2 Score as an Independent Predictor of 1-Year Mortality in Patients with Heart Failure with Preserved Ejection Fraction.","authors":"Halit Emre Yalvaç, Ezgi Çamlı Babayiğit, Hazal Dağhan","doi":"10.14744/AnatolJCardiol.2026.6689","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2026.6689","url":null,"abstract":"<p><strong>Background: </strong>Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome with substantial early morbidity and mortality. The BREATH2 score was recently developed as an echocardiography-independent screening tool for HFpEF. However, its prognostic significance has not been investigated. This study aimed to evaluate the association between the BREATH2 score and 1-year all-cause mortality in patients with established HFpEF.</p><p><strong>Methods: </strong>A total of 213 patients with HFpEF were retrospectively analyzed. The primary endpoint was 1-year all-cause mortality. Discriminative performance of the BREATH2, H2FPEF, and HFA-PEFF scores was assessed using receiver operating characteristic analysis. Multiple logistic regression was performed to identify independent predictors of mortality. Kaplan-Meier survival analysis was conducted using a prespecified BREATH2 cut-off (≥6).</p><p><strong>Results: </strong>During 12-month follow-up, 32 patients (15.0%) died. The BREATH2 score was significantly higher among non-survivors (P = .001). Receiver operating characteristic curve analysis demonstrated that BREATH2 had the highest discriminative ability for 1-year mortality (area under the curve [AUC] = 0.683, P < .001, 95% CI: 0.616-0.745), outperforming H2FPEF (AUC = 0.554, P = .324) and HFA-PEFF (AUC = 0.593, P < .001). In multiple analyses adjusting for age, creatinine, and N-terminal pro-B-type natriuretic peptide, BREATH2 remained independently associated with mortality (odds ratio = 1.658 per 1-point increase, P = .021, 95% CI: 1.078-2.551). Patients with BREATH2 ≥6 had significantly lower survival compared with those with lower scores(log-rank, P = .013).</p><p><strong>Conclusion: </strong>The BREATH2 score independently predicts 1-year mortality in patients with HFpEF. Beyond its diagnostic role, BREATH2 may serve as a practical early risk stratification tool at initial clinical presentation.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148824029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Osaka Prognostic Score in Assessing Infrapopliteal Lesion Complexity and Predicting Procedural Technical Success After Endovascular Intervention: A Retrospective Study.","authors":"Alperen Taş, Çağatay Tunca, Emine Cansu Yücel, Muhammed Erzurum, Ayşenur Özkaya İbiş, Mehmet Taha Özkan","doi":"10.14744/AnatolJCardiol.2026.6610","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2026.6610","url":null,"abstract":"<p><strong>Background: </strong>Peripheral artery disease (PAD) is a progressive atherosclerotic disorder affecting lower extremities. While anatomical classification systems like Trans-Atlantic Inter-Society Consensus (TASC) aid procedural planning, they lack systemic prognostic components. The Osaka Prognostic Score (OPS), incorporating C-reactive protein, albumin, and lymphocyte count, is an emerging biomarker-based index that may aid in stratifying PAD severity. This study aimed to evaluate whether OPS is associated with infrapopliteal lesion complexity and to determine its predictive value for procedural technical success in patients undergoing endovascular intervention.</p><p><strong>Methods: </strong>This retrospective study included 154 patients undergoing lower extremity percutaneous transluminal angioplasty. Procedures were performed using standard femoral access under fluoroscopic guidance. Technical success was defined as <30% residual stenosis without impairment. The OPS was calculated preoperatively, and outcomes were analyzed.</p><p><strong>Results: </strong>Higher OPS and low-density lipoprotein (LDL) levels were significantly associated with TASC C-D lesions. Technical success was significantly lower in advanced lesions. The OPS was independently associated with advanced lesion category and procedural technical failure, outperforming LDL in receiver operating characteristic analysis.</p><p><strong>Conclusion: </strong>The OPS was independently associated with infrapopliteal lesion complexity and procedural technical success in patients undergoing endovascular intervention for PAD. These findings suggest that OPS may serve as a useful adjunct to anatomical classification for preprocedural risk stratification. Further prospective studies with long-term clinical follow-up are needed to validate these findings.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148811582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-Session Percutaneous Left Atrial Appendage Occlusion and Atrial Septal Defect Closure Guided by Balloon Occlusion Testing in an Elderly Patient with Recurrent Gastrointestinal Bleeding Under Non-vitamin K Antagonist Oral Anticoagulants Therapy.","authors":"Şenol Coşkun, Teoman Kılıç","doi":"10.14744/AnatolJCardiol.2026.6723","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2026.6723","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148811606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Presentation, Diagnosis, Treatment, and Outcome of Heart Disease in Becker Muscular Dystrophy.","authors":"Josef Finsterer","doi":"10.14744/AnatolJCardiol.2026.6700","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2026.6700","url":null,"abstract":"<p><p>Becker muscular dystrophy (BMD) is a primary myopathy caused by mutations in the dystrophin gene on chromosome Xq21.2, which often affects the myocardium and cardiac conduction system. However, there is limited experience with cardiac disease in BMD. This review aims to summarize and discuss recent advances and future perspectives regarding the clinical presentation, diagnosis, treatment, and outcome of cardiac involvement in BMD. Data were retrieved by searching for relevant articles in the PubMed and Google Scholar databases. Cardiac disease in BMD is characterized by myocardial fibrosis, can be subclinical or clinical, and manifests as left or right ventricular systolic dysfunction with/without heart failure due to dilated or hypertrophic cardiomyopathy, diastolic dysfunction with preserved/decreased systolic function, conduction disturbances and supraventricular/ventricular arrhythmias, thrombus formation, arterial hypertension, pulmonary hypertension, left ventricular hypertrabeculation, coronary artery disease, and valve defects. Cardiac involvement in BMD must be detected and treated at an early stage, because it progresses over time and has a significant impact on the course of the disease. Established treatment methods include non-invasive therapies with small molecules and catheter-based invasive therapies (stent implantation, endocardial and epicardial ablation), device-related treatments (pacemaker, implantable cardioverter-defibrillator, cardiac resynchronization therapy, left ventricular assist device), and heart surgery. Cardiac involvement in BMD occurs in about two-thirds of patients, is subclinical in the early stages but becomes symptomatic as the heart disease progresses, requires early diagnosis, and can be treated with non-invasive and invasive therapies, with prognosis improving with early detection and adequate treatment.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148808107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antiplatelet Strategy After Drug-Coated Balloon Angioplasty for Isolated Side Branch Lesions: The Missing Piece of the Puzzle.","authors":"Ahmet Can Çakmak, Betül Sarıbıyık Çakmak","doi":"10.14744/AnatolJCardiol.2026.6889","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2026.6889","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148808102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between Estimated Pulse Wave Velocity and Mortality Risk in Patients with Atrial Fibrillation: A Retrospective Cohort Analysis of Medical Information Mart for Intensive Care-IV Database.","authors":"Nan Xia, Ye Cao","doi":"10.14744/AnatolJCardiol.2026.6392","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2026.6392","url":null,"abstract":"<p><strong>Objective: </strong>Pulse wave velocity (PWV) serves as a reliable indicator of arterial stiffness and is correlated with the occurrence and prognosis of cardiovascular diseases. This analysis investigates the connection of estimated PWV (ePWV) with mortality risk among atrial fibrillation (AF) patients.</p><p><strong>Methods: </strong>This retrospective cohort analysis incorporated data on critically ill AF patients derived from the Medical Information Mart for Intensive Care-IV (2008-2022). Estimated pulse wave velocity was computed by a validated formula. The connection of ePWV with mortality risk was examined using Cox regression analyses. Restricted cubic spline (RCS) curves were employed to evaluate the non-linear correlation and to determine the cutoff values for ePWV classification.</p><p><strong>Results: </strong>Of these 14 659 AF patients enrolled, 30-day mortality occurred in 2587 (17.65%) patients, and 1-year mortality in 4765 (32.51%) patients. The RCS curves presented a non-linear correlation of ePWV with both 30-day and 1-year mortality risk (P < .001). Patients with ePWV levels ≥ 11.302 m/s had a higher risk of 30-day mortality (hazard ratio [HR] = 1.20 [95% CI: 1.06-1.19]) and 1-year mortality (HR = 1.11 [95% CI: 1.02-1.21]) versus those with ePWV < 11.302 m/s, and this correlation was also observed in subgroups according to age, gender, Sequential Organ Failure Assessment (SOFA) score, heart failure, vasoactive drugs, and AF types (P < .05). Moreover, ePWV levels combined with the SOFA score were a better predictor of 30-day/1-year mortality than the SOFA score alone.</p><p><strong>Conclusion: </strong>Elevated ePWV levels were connected with a higher risk of short-term mortality among AF patients, and ePWV presented prognostic predictive ability.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148808084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Follow-Up of a Patient with Arterial Tortuosity Syndrome After Bilateral Pulmonary Artery Stent Implantation.","authors":"Çağan Yıldırım, Halil Ataş","doi":"10.14744/AnatolJCardiol.2026.6686","DOIUrl":"10.14744/AnatolJCardiol.2026.6686","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148720748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-Sectional Mediation and Biomarker Interpretation in the Report by Yan and Gao.","authors":"Hasan Burak İşleyen, Sercan Bulut","doi":"10.14744/AnatolJCardiol.2026.6665","DOIUrl":"10.14744/AnatolJCardiol.2026.6665","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148722505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Treatment of Ascending Aortic Pseudoaneurysms: A Case Series.","authors":"Fatma Can, Muhsin Melik, Gönül Zeren, İlhan İlker Avcı, Mustafa Azmi Sungur, Melih Öz, Utku Uluköksal, Barış Şimşek, Mehmet Fatih Yılmaz, Can Yücel Karabay","doi":"10.14744/AnatolJCardiol.2026.6424","DOIUrl":"10.14744/AnatolJCardiol.2026.6424","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148720076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}