{"title":"Reply to Letter to the Editor: \"Current Guidelines Should be Taken into Consideration in the Management of Dyslipidemia\".","authors":"Taner Şen","doi":":10.14744/AnatolJCardiol.2024.5027","DOIUrl":":10.14744/AnatolJCardiol.2024.5027","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":"29 2","pages":"106-107"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11793798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmet Güner, Ahmet Yaşar Çizgici, Fatih Furkan Bedir, İbrahim Faruk Aktürk, Fatih Uzun
{"title":"Double TAP Technique for Left Main Trifurcation.","authors":"Ahmet Güner, Ahmet Yaşar Çizgici, Fatih Furkan Bedir, İbrahim Faruk Aktürk, Fatih Uzun","doi":"10.14744/AnatolJCardiol.2025.5078","DOIUrl":"10.14744/AnatolJCardiol.2025.5078","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":"29 2","pages":"108-109"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11793805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hüseyin Bozbaş, Cem Barçın, Mohamed Asfour, Savaş A Çelebi, Ersin Çam, Erdoğan İlkay
{"title":"Caval Valve Implantation Procedure in 7 Cases of Torrential Tricuspid Regurgitation and Step-by-Step Description of the Procedure.","authors":"Hüseyin Bozbaş, Cem Barçın, Mohamed Asfour, Savaş A Çelebi, Ersin Çam, Erdoğan İlkay","doi":"10.14744/AnatolJCardiol.2025.4750","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2025.4750","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Nitroglycerine Injection on Radial Artery Outcomes in Distal Transradial Access.","authors":"Mehmet Karaca, Bahadır Dağdeviren","doi":"10.14744/AnatolJCardiol.2025.4877","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2025.4877","url":null,"abstract":"<p><strong>Background: </strong>Preventive measures for radial artery complications in distal transradial approach are not fully studied. Our aim was to investigate the role of nitroglycerine injection in patients undergoing coronary angiography via distal transradial access.</p><p><strong>Methods: </strong>In this study, 168 patients who underwent angiographic procedures performed via distal transradial route with or without nitroglycerine injection were evaluated. Demographic, angiographic, and laboratory characteristics were recorded. Radial artery outcomes, including radial artery spasm, radial artery occlusion, and hematoma were compared between these groups and P values < .05 indicated significant differences.</p><p><strong>Results: </strong>Radial artery outcome occurred in 22% of the study population (n = 37), with radial artery spasm being the most encountered complication (n = 28, 16.7%). The groups were not different in terms of radial artery complications. Procedural features were also comparable except for the total contrast volume used.</p><p><strong>Conclusion: </strong>Coronary angiographic procedures could be performed safely using distal transradial access without nitroglycerine injection.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Müge Akbulut, Arzu Keskin Aktan, Gizem Sonugür, Saadet Özen Akarca, Aslı Nur Bahar, Hatice Kavak, Gonca Akbulut
{"title":"Protective Effects of SIRT2 Inhibition on Cardiac Fibrosis.","authors":"Müge Akbulut, Arzu Keskin Aktan, Gizem Sonugür, Saadet Özen Akarca, Aslı Nur Bahar, Hatice Kavak, Gonca Akbulut","doi":"10.14744/AnatolJCardiol.2025.4770","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2025.4770","url":null,"abstract":"<p><strong>Background: </strong>A primary factor in the pathogenesis of aging is oxidative stress, with cardiac inflammation and fibrosis being contributed to by increased oxidative stress as organisms age. Oxidative stress enhances the cardiac fibrotic signaling pathway, with reactive oxygen species inducing cardiac fibrosis through increased expression of the profibrotic factor transforming growth factor-beta 1 (TGF-β1). Furthermore, Wnt/β-catenin signaling pathway is implicated in interstitial fibrosis, which is associated with TGF-β. Sirtuin 2 (SIRT2) is expressed in heart tissue, with protective effects in pathological cardiac hypertrophy. We aimed to investigate the mechanisms of cardiac fibrosis in D-Galactose (D-Gal)-induced accelerated aging, focusing on TGF-β1, β-catenin, and SIRT2.</p><p><strong>Methods: </strong>A total of 30 young male Sprague-Dawley rats were randomly divided into 4 groups: control group, D-Gal group, D-Gal + 4% dimethyl sulfoxide (DMSO) group, and D-Gal + the SIRT2 inhibitor (AGK2) group. After 10 weeks, the rats were sacrificed, and their hearts were removed. SIRT2 expression levels were measured by western blot and gene expression levels of TGF-β1 and β-catenin by quantitative real-time polymerase chain reaction.</p><p><strong>Results: </strong>Transforming growth factor-beta 1 (TGF-β1) mRNA expression in heart tissue was higher in the D-Gal group compared to all other groups. β-catenin mRNA expression was higher in the D-Gal group than in the D-Gal + AGK2 group. SIRT2 protein expression was higher in the D-Gal + DMSO group compared to the control group. Sirtuin 2 expression was lower in the D-Gal + AGK2 group compared to the D-Gal and D-Gal + DMSO groups.</p><p><strong>Conclusion: </strong>Sirtuin 2 inhibition attenuates fibrosis, as evidenced by the downregulation of TGF-β1 and β-catenin. Thus, targeting SIRT2 may represent a potential therapeutic strategy for diseases characterized by cardiac fibrosis in the future.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Uğur Nadir Karakulak, Cem Çöteli, Hikmet Yorgun, Kudret Aytemir
{"title":"Severe Diarrhea After Atrial Fibrillation Ablation and The Role of Vagal Plexus: A Case Series.","authors":"Uğur Nadir Karakulak, Cem Çöteli, Hikmet Yorgun, Kudret Aytemir","doi":"10.14744/AnatolJCardiol.2025.4722","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2025.4722","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Similar to the Original: Accessory Mitral Valve.","authors":"Uğur Nadir Karakulak","doi":"10.14744/AnatolJCardiol.2025.4328","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2025.4328","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adult-Onset Still's Disease: A Rare Cause of Acute Severe Mitral Regurgitation.","authors":"Ezgi Çamlı Babayiğit, Emre Şener, Erdi Babayiğit","doi":"10.14744/AnatolJCardiol.2025.4984","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2025.4984","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alaa S Algazzar, Raghad M Aljondi, Eilaf Majdi Metwalli, Ghazal Y Dhaher, Hanan H Mushaeb, Renad H Aljadani, Rahaf S Balahmar, Awatif Hafiz, Mohamed A Qutub
{"title":"Comparison of 1-Year Clinical Outcomes Between Ticagrelor Versus Clopidogrel in Type 2 Diabetes Patients After Implantation of Small Diameter Stents.","authors":"Alaa S Algazzar, Raghad M Aljondi, Eilaf Majdi Metwalli, Ghazal Y Dhaher, Hanan H Mushaeb, Renad H Aljadani, Rahaf S Balahmar, Awatif Hafiz, Mohamed A Qutub","doi":"10.14744/AnatolJCardiol.2024.4603","DOIUrl":"10.14744/AnatolJCardiol.2024.4603","url":null,"abstract":"<p><strong>Background: </strong>Type 2 diabetes mellitus (T2DM) patients with small-diameter stents (SDS), that are equal to or less than 2.5 mm in diameter, face increased risks of restenosis and complications. This study aimed to evaluate the 1-year follow-up to assess the rate of major adverse cardiac events (MACE) and bleeding risk between ticagrelor and clopidogrel in T2DM patients after SDS implantation.</p><p><strong>Methods: </strong>The study was a single-center, prospective controlled registry trial, which included 332 T2DM patients who underwent percutaneous coronary intervention with SDS implantation. Follow-up was conducted for 1 year.</p><p><strong>Results: </strong>Following propensity score matching, the 1-year analysis revealed no significant difference in the risk of the composite MACE between clopidogrel and ticagrelor groups (P = .295). Male gender, history of ischemic heart disease, ejection fraction (EF), coronary lesion type, and chronic kidney disease (CKD) were identified as potential predictors for the composite endpoint. In a subanalysis of CKD patients, the 12-month rates of composites of cardiac death (CD), myocardial infarction (MI), stroke, and target vessel revascularization (TVR) were lower in the ticagrelor group than in the clopidogrel group (P = .024). However, the ticagrelor group was associated with a higher rate of bleeding compared to the clopidogrel group (20% vs. 9%) (P = .041).</p><p><strong>Conclusion: </strong>Our study demonstrated that ticagrelor did not show improvement in the composite of CD, MI, stroke, TVR, or the risk of bleeding events defined by the BARC criteria in patients with T2DM and SDS compared with clopidogrel emphasizing the importance of individualized treatment decisions based on patient characteristics. However, the results may not be representative of the entire population.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11793804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}