Anatolian Journal of Cardiology最新文献

{"title":"Ultrasound-Assisted Catheter-Directed Thrombolytic Therapy Vs. Anticoagulation in Acute Intermediate-High Risk Pulmonary Embolism: A Quasi-Experimental Study.","authors":"Barkın Kültürsay, Berhan Keskin, Seda Tanyeri, Hacer Ceren Tokgöz, Aykun Hakgör, Çağdaş Buluş, Deniz Mutlu, Ahmet Sekban, Dicle Sırma, Şeyhmus Külahçıoğlu, Abdulkadir Uslu, Ali Karagöz, İbrahim Halil Tanboğa, Nihal Özdemir, Cihangir Kaymaz","doi":"10.14744/AnatolJCardiol.2025.5127","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2025.5127","url":null,"abstract":"<p><strong>Background: </strong>Given the bleeding risk associated with full-dose intravenous thrombolytic treatment and the absence of randomized clinical trial evidence, current guidelines do not recommend reperfusion treatments as first-line therapy for intermediate-high risk (IHR) pulmonary embolism (PE). The aim of this study was to evaluate the effectiveness and safety of ultrasound-assisted catheter-directed thrombolysis (USAT) compared to anticoagulation therapy alone in patients with IHR PE.</p><p><strong>Methods: </strong>A total of 425 patients diagnosed with acute PE and determined as IHR, 203 of whom underwent USAT, and 222 patients receiving only anticoagulants as the control group, were included. Baseline and post-treatment right ventricle (RV) function in echocardiography, tomographic RV/left ventricle (RV/LV) ratio, Qanadli score (Qs), and % changes from baseline were taken as primary effectiveness outcomes. For safety outcomes, major and minor bleeding and in-hospital all-cause death were adopted. Propensity score analysis was performed to reduce confounders and bias.</p><p><strong>Results: </strong>The USAT treatment was found to be associated with improved RV function and decreased Qs, but no significant effect was observed on the RV/LV ratio and its change. Bleeding events were more frequent in the USAT group (P < .001 for both), and no difference was observed in terms of mortality.</p><p><strong>Conclusion: </strong>The study, based on real-life data, has shown that a moderate-dose, slow-infusion tissue-type plasminogen activator regimen is superior to anticoagulant therapy alone in terms of reducing pulmonary arterial thrombus burden, restoring RV dysfunction, and improving clinical outcomes in acute PE patients at IHR. However, it has also resulted in a slight increase in bleeding events.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining ECG Parameters for Electrical Risk Score in Patients with Non-ST Elevation Myocardial Infarction.","authors":"Can Ramazan Öncel, Ali Çoner, Cemal Köseoğlu","doi":"10.14744/AnatolJCardiol.2025.5205","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2025.5205","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visualization of Double-Chambered Left Ventricle by Multimodality Imaging.","authors":"Zhenni Wu, Yali Yang, Lin He, Yuman Li","doi":"10.14744/AnatolJCardiol.2025.5307","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2025.5307","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Bail-Out 2-Stent Technique for Coronary Bifurcation Disease: Reverse Controlled Balloon- Crush.","authors":"Berkay Serter, Ahmet Güner, Koray Çiloğlu, Abdullah Doğan, Fatih Uzun","doi":"10.14744/AnatolJCardiol.2025.5231","DOIUrl":"10.14744/AnatolJCardiol.2025.5231","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":"29 4","pages":"5011-5012"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to Letter to the Editor: \"Unmet Need for Deep Diving into Intracoronary Imaging\".","authors":"Mert Doğan, Ahmet Hakan Ateş, Uğur Canpolat","doi":"10.14744/AnatolJCardiol.2025.5226","DOIUrl":"10.14744/AnatolJCardiol.2025.5226","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":"29 4","pages":"207-208"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence in Cardiology: General Perspectives and Focus on Interventional Cardiology.","authors":"Giuseppe Biondi-Zoccai, Fabrizio D'Ascenzo, Salvatore Giordano, Ulvi Mirzoyev, Çetin Erol, Sabrina Cenciarelli, Pietro Leone, Francesco Versaci","doi":"10.14744/AnatolJCardiol.2025.5237","DOIUrl":"10.14744/AnatolJCardiol.2025.5237","url":null,"abstract":"<p><p>Artificial intelligence (AI) is being intensively applied to cardiology, particularly in diagnostics, risk prediction, treatment planning, and invasive procedures. While AI-driven advancements have demonstrated promise, their real-world implementation remains constrained by critical challenges. Current AI applications, such as electrocardiogram interpretation and automated imaging analysis, have improved diagnostic accuracy and workflow efficiency, yet generalizability, regulatory hurdles, and integration into existing clinical workflows remain major obstacles. Algorithmic bias and the lack of explainable AI further complicate widespread adoption, potentially leading to disparities in healthcare outcomes. In interventional cardiology, robotic-assisted percutaneous coronary intervention has emerged as a technological innovation, but comparative clinical evidence supporting its superiority (or even non-inferiority) over conventional approaches is still limited. Additionally, AI-based decision support systems in high-risk cardiovascular procedures require rigorous validation to ensure safety and reliability. Ethical considerations, including patient data security and region-specific regulatory frameworks, also pose significant barriers. Addressing these challenges requires interdisciplinary collaboration, robust external validation, and the development of transparent, interpretable AI models. This review provides a critical appraisal of the current role of AI in cardiology, emphasizing both its potential and its limitations, and outlines future directions to facilitate its responsible integration into clinical practice.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":"29 4","pages":"152-163"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unmet Need for Deep Diving into Intracoronary Imaging.","authors":"Aykun Hakgör, Berhan Keskin, Seda Tanyeri Uzel, Barkın Kültürsay","doi":"10.14744/AnatolJCardiol.2025.5222","DOIUrl":"10.14744/AnatolJCardiol.2025.5222","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":"29 4","pages":"205-206"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Articial Intelligence in Cardiology and new studies..","authors":"Çetin Erol","doi":"10.14744/AnatolJCardiol.2025.4","DOIUrl":"10.14744/AnatolJCardiol.2025.4","url":null,"abstract":"","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":"29 4","pages":"151"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic-Assisted Coronary Artery Bypass Grafting vs. Percutaneous Coronary Intervention Strategies for Ostial Left Anterior Descending Lesions.","authors":"Mehmet Köseoğlu, Cemalettin Akman, Ahmet Güner, Koray Çiloğlu, Berkay Serter, Ünal Aydın, Ahmet Yaşar Çizgici, Ersin Kadiroğulları, Taner İyigün, Cemil Can, Ali Rıza Demir, Fatih Furkan Bedir, Ezgi Gültekin Güner, Abdullah Doğan, Yasin Ay, Fatih Uzun","doi":"10.14744/AnatolJCardiol.2025.5050","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2025.5050","url":null,"abstract":"<p><strong>Background: </strong>The comparison of outcomes of robotic-assisted coronary artery bypass grafting (RA-CABG) vs. stenting techniques (ostial or crossover stenting) for ostial left anterior descending (LAD) artery lesions is still lacking. This retrospective study sought to determine the midterm outcomes of RA-CABG, crossover stenting (CS), and ostial stent implantation (OSI) in patients with ostial LAD disease.</p><p><strong>Methods: </strong>All cases were divided into 3 groups as follows: RA-CABG (group 1) (n = 157), CS (group 2) (n = 104), and OSI (group 3) (n = 178). The primary endpoint was defined  as  the major adverse cardiac and cerebral events (MACCE), which included cardiac death, target vessel myocardial infarction, target vessel revascularization (TVR), stroke, and stent thrombosis or symptomatic graft occlusion during follow-up. This is the first investigation comparing midterm outcomes of RA-CABG, CS, and OSI as revascularization options for ostial LAD lesions.</p><p><strong>Results: </strong>A total of 439 consecutive individuals [male: 341 (77.6%), mean age: 59.58 ± 9.35 years] with ostial LAD disease were included in this study. The rates of MACCE (P = .020 for groups 3 vs. 1; P = .011 for groups 3 vs. 2) and clinically driven TVR (15.7 vs. 4.5%, P = .001 for groups 3 vs. 1; 15.7 vs. 5.8%, P = .014 for groups 3 vs. 2) were notably higher in group 3 than the others. The mid-term MACCE [(adjusted hazard ratio = 2.129  [95%  confidence interval: 1.360-3.334], P = .001)]  in  the  overall  population  significantly  differed  between group 3 and the others.</p><p><strong>Conclusion: </strong> The findings of the study suggest that OSI for ostial LAD lesions was associated with higher midterm MACCE and TVR rates than revascularization with RA-CABG or CS.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 Infection, Vaccination, and Severe Coronary Artery Disease in Türkiye: A Retrospective Analysis.","authors":"Esma Çetinkaya, Ayşe Taş","doi":"10.14744/AnatolJCardiol.2025.5105","DOIUrl":"https://doi.org/10.14744/AnatolJCardiol.2025.5105","url":null,"abstract":"<p><strong>Background: </strong>This study addresses a topic that has been explored globally but has not yet been investigated in the Türkiye. Considering that all diseases and treatments may vary due to genetic diversity, the aim is to examine the effects of the coronavirus disease 2019 (COVID-19) vaccine and COVID-19 disease on heart conditions in patients in the Türkiye.</p><p><strong>Methods: </strong>A total of 1935 patients who underwent angiography were included in the study. Descriptive statistics were provided in terms of numbers and percentages, as well as means and SD.</p><p><strong>Results: </strong>There was no relationship found between the occurrence of COVID-19 at any time before data collection and the presence of severe coronary artery disease (CAD). Additionally, there was no relationship found between the time elapsed between COVID-19 infection and angiography and the presence of severe CAD among individuals who underwent angiography at a later date (n = 689). Between November 2021 and May 2022 (fifth 6 months) and May 2022 and November 2022 (sixth 6 months), the rates of severe CAD in angiograms conducted compared to the baseline were higher. There was no significant relationship found between the number of doses of messenger ribonucleic acid (mRNA) vaccine received and the risk of developing severe CAD (P = .139). Similarly, there was no significant relationship found between the number of doses of inactivated vaccine received and the risk of developing severe CAD (P = .382).</p><p><strong>Conclusion: </strong>In the long term, neither infection nor vaccination increases the risk of cardiovascular disease, regardless of the time elapsed since the COVID-19 infection or the type of vaccination received.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}